| Records |
| Author |
Borja-Lloret, M.; Barrientos, L.; Bernabeu, J.; Lacasta, C.; Muñoz, E.; Ros, A.; Roser, J.; Viegas, R.; Llosa, G. |
| Title |
Influence of the background in Compton camera images for proton therapy treatment monitoring |
Type |
Journal Article |
Year  |
2023 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
| Volume |
68 |
Issue |
14 |
Pages |
144001 - 16pp |
| Keywords |
Compton imaging; Compton camera; proton therapy; treatment monitoring; Monte Carlo simulation; image reconstruction; background |
| Abstract |
Objective. Background events are one of the most relevant contributions to image degradation in Compton camera imaging for hadron therapy treatment monitoring. A study of the background and its contribution to image degradation is important to define future strategies to reduce the background in the system. Approach. In this simulation study, the percentage of different kinds of events and their contribution to the reconstructed image in a two-layer Compton camera have been evaluated. To this end, GATE v8.2 simulations of a proton beam impinging on a PMMA phantom have been carried out, for different proton beam energies and at different beam intensities. Main results. For a simulated Compton camera made of Lanthanum (III) Bromide monolithic crystals, coincidences caused by neutrons arriving from the phantom are the most common type of background produced by secondary radiations in the Compton camera, causing between 13% and 33% of the detected coincidences, depending on the beam energy. Results also show that random coincidences are a significant cause of image degradation at high beam intensities, and their influence in the reconstructed images is studied for values of the time coincidence windows from 500 ps to 100 ns. Significance. Results indicate the timing capabilities required to retrieve the fall-off position with good precision. Still, the noise observed in the image when no randoms are considered make us consider further background rejection methods. |
| Address |
[Borja-Lloret, M.; Barrientos, L.; Bernabeu, J.; Lacasta, C.; Munoz, E.; Ros, A.; Roser, J.; Viegas, R.; Llosa, G.] Inst Fis Corpuscular IFIC, CSIC UV, Valencia, Spain, Email: Marina.Borja@csic.es |
| Corporate Author |
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Thesis |
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| Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0031-9155 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:001022671300001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
5571 |
| Permanent link to this record |
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| Author |
Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Muñoz, E.; Ros, A.; Viegas, R.; Llosa, G. |
| Title |
Joint image reconstruction algorithm in Compton cameras |
Type |
Journal Article |
| Year |
2022 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
| Volume |
67 |
Issue |
15 |
Pages |
155009 - 15pp |
| Keywords |
Compton camera; compton imaging; hadron therapy; image reconstruction; LM-MLEM; Monte Carlo simulations; multi-layer compton telescope |
| Abstract |
Objective. To demonstrate the benefits of using an joint image reconstruction algorithm based on the List Mode Maximum Likelihood Expectation Maximization that combines events measured in different channels of information of a Compton camera. Approach. Both simulations and experimental data are employed to show the algorithm performance. Main results. The obtained joint images present improved image quality and yield better estimates of displacements of high-energy gamma-ray emitting sources. The algorithm also provides images that are more stable than any individual channel against the noisy convergence that characterizes Maximum Likelihood based algorithms. Significance. The joint reconstruction algorithm can improve the quality and robustness of Compton camera images. It also has high versatility, as it can be easily adapted to any Compton camera geometry. It is thus expected to represent an important step in the optimization of Compton camera imaging. |
| Address |
[Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Munoz, E.; Ros, A.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Jorge.Roser@ific.uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0031-9155 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
|
| Notes |
WOS:000827830200001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
5298 |
| Permanent link to this record |
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| Author |
Balibrea-Correa, J.; Lerendegui-Marco, J.; Babiano-Suarez, V.; Caballero, L.; Calvo, D.; Ladarescu, I.; Olleros-Rodriguez, P.; Domingo-Pardo, C. |
| Title |
Machine Learning aided 3D-position reconstruction in large LaCl3 crystals |
Type |
Journal Article |
| Year |
2021 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
| Volume |
1001 |
Issue |
|
Pages |
165249 - 17pp |
| Keywords |
Gamma-ray; Position sensitive detectors; Monolithic crystals; Compton imaging; Machine Learning; Convolutional Neural Networks; Total Energy Detector; Neutron capture cross-section |
| Abstract |
We investigate five different models to reconstruct the 3D gamma-ray hit coordinates in five large LaCl3(Ce) monolithic crystals optically coupled to pixelated silicon photomultipliers. These scintillators have a base surface of 50 x 50 mm(2) and five different thicknesses, from 10 mm to 30 mm. Four of these models are analytical prescriptions and one is based on a Convolutional Neural Network. Average resolutions close to 1-2 mm fwhm are obtained in the transverse crystal plane for crystal thicknesses between 10 mm and 20 mm using analytical models. For thicker crystals average resolutions of about 3-5 mm fwhm are obtained. Depth of interaction resolutions between 1 mm and 4 mm are achieved depending on the distance of the interaction point to the photosensor surface. We propose a Machine Learning algorithm to correct for linearity distortions and pin-cushion effects. The latter allows one to keep a large field of view of about 70%-80% of the crystal surface, regardless of crystal thickness. This work is aimed at optimizing the performance of the so-called Total Energy Detector with Compton imaging capability (i-TED) for time-of-flight neutron capture cross-section measurements. |
| Address |
[Balibrea-Correa, J.; Lerendegui-Marco, J.; Babiano-Suarez, V.; Caballero, L.; Calvo, D.; Ladarescu, I.; Olleros-Rodriguez, P.; Domingo-Pardo, C.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: javier.balibrea@ific.uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Elsevier |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0168-9002 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
|
| Notes |
WOS:000641308300007 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
4803 |
| Permanent link to this record |
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| Author |
Babiano, V.; Balibrea, J.; Caballero, L.; Calvo, D.; Ladarescu, I.; Mira Prats, S.; Domingo-Pardo, C. |
| Title |
First i-TED demonstrator: A Compton imager with Dynamic Electronic Collimation |
Type |
Journal Article |
| Year |
2020 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
| Volume |
953 |
Issue |
|
Pages |
163228 - 9pp |
| Keywords |
Compton imaging; Position-sensitive detectors; Monolithic crystals; Silicon photomultiplier |
| Abstract |
i-TED consists of both a total energy detector and a Compton camera primarily intended for the measurement of neutron capture cross sections by means of the simultaneous combination of neutron time-of-flight (TOF) and gamma-ray imaging techniques. TOF allows one to obtain a neutron-energy differential capture yield, whereas the imaging capability is intended for the discrimination of radiative background sources, that have a spatial origin different from that of the capture sample under investigation. A distinctive feature of i-TED is the embedded Dynamic Electronic Collimation (DEC) concept, which allows for a trade-off between efficiency and image resolution. Here we report on some general design considerations and first performance characterization measurements made with an i-TED demonstrator in order to explore its gamma-ray detection and imaging capabilities. |
| Address |
[Babiano, V; Balibrea, J.; Caballero, L.; Calvo, D.; Ladarescu, I; Mira Prats, S.; Domingo-Pardo, C.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: domingo@ific.uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Elsevier |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0168-9002 |
ISBN |
|
Medium |
|
| Area |
|
Expedition |
|
Conference |
|
| Notes |
WOS:000506419900045 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
4250 |
| Permanent link to this record |
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| Author |
Muñoz, E.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Llosa, G.; Ros, A.; Roser, J.; Oliver, J.F. |
| Title |
A spectral reconstruction algorithm for two-plane Compton cameras |
Type |
Journal Article |
| Year |
2020 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
| Volume |
65 |
Issue |
2 |
Pages |
025011 - 17pp |
| Keywords |
Compton imaging; Compton camera; hadron therapy; image reconstruction |
| Abstract |
One factor limiting the current applicability extent of hadron therapy is the lack of a reliable method for real time treatment monitoring. The use of Compton imaging systems as monitors requires the correct reconstruction of the distribution of prompt gamma productions during patient irradiation. In order to extract the maximum information from all the measurable events, we implemented a spectral reconstruction method that assigns to all events a probability of being either partial or total energy depositions. The method, implemented in a list-mode maximum likelihood expectation maximization algorithm, generates a four dimensional image in the joint spatial-spectral domain, in which the voxels containing the emission positions and energies are obtained. The analytical model used for the system response function is also employed to derive an analytical expression for the sensitivity, which is calculated via Monte Carlo integration. The performance of the method is evaluated through reconstruction of various experimental and simulated sources with different spatial and energy distributions. The results show that the proposed method can recover the spectral and spatial information simultaneously, but only under the assumption of ideal measurements. The analysis of the Monte Carlo simulations has led to the identification of two important degradation sources: the mispositioning of the gamma interaction point and the missing energy recorded in the interaction. Both factors are related to the high energy transferred to the recoil electrons, which can travel far from the interaction point and even escape the detector. These effects prevent the direct application of the current method in more realistic scenarios. Nevertheless, experimental point-like sources have been accurately reconstructed and the spatial distributions and spectral emission of complex simulated phantoms can be identified. |
| Address |
[Munoz, Enrique; Barrientos, Luis; Bernabeu, Jose; Borja-Lloret, Marina; Llosa, Gabriela; Ros, Ana; Roser, Jorge; Oliver, Josep F.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
|
Original Title |
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| Series Editor |
|
Series Title |
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Abbreviated Series Title |
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| Series Volume |
|
Series Issue |
|
Edition |
|
| ISSN |
0031-9155 |
ISBN |
|
Medium |
|
| Area |
|
Expedition |
|
Conference |
|
| Notes |
WOS:000520111400001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
4332 |
| Permanent link to this record |
