Abstract: GW190521 is the compact binary with the largest masses observed to date, with at least one black hole in the pair-instability gap. This event has also been claimed to be associated with an optical flare observed by the Zwicky Transient Facility in an active galactic nucleus (AGN), possibly due to the postmerger motion of the merger remnant in the AGN gaseous disk. The Laser Interferometer Space Antenna (LISA) may detect up to ten such gas-rich black-hole binaries months to years before their detection by Laser Interferometer Gravitational Wave Observatory or Virgo-like interferometers, localizing them in the sky within approximate to 1 degrees(2). LISA will also measure directly deviations from purely vacuum and stationary waveforms arising from gas accretion, dynamical friction, and orbital motion around the AGN's massive black hole (acceleration, strong lensing, and Doppler modulation). LISA will therefore be crucial to enable us to point electromagnetic telescopes ahead of time toward this novel class of gas-rich sources, to gain direct insight on their physics, and to disentangle environmental effects from corrections to general relativity that may also appear in the waveforms at low frequencies.

Abstract: Patient Trajectories (PTs) are a method of representing the temporal evolution of patients. They can include information from different sources and be used in socio-medical or clinical domains. PTs have generally been used to generate and study the most common trajectories in, for instance, the development of a disease. On the other hand, healthcare predictive models generally rely on static snapshots of patient information. Only a few works about prediction in healthcare have been found that use PTs, and therefore benefit from their temporal dimension. All of them, however, have used PTs created from single-source information. Therefore, the use of longitudinal multi-scale data to build PTs and use them to obtain predictions about health conditions is yet to be explored. Our hypothesis is that local similarities on small chunks of PTs can identify similar patients concerning their future morbidities. The objectives of this work are (1) to develop a methodology to identify local similarities between PTs before the occurrence of morbidities to predict these on new query individuals; and (2) to validate this methodology on risk prediction of cardiovascular diseases (CVD) occurrence in patients with diabetes. We have proposed a novel formal definition of PTs based on sequences of longitudinal multi-scale data. Moreover, a dynamic programming methodology to identify local alignments on PTs for predicting future morbidities is proposed. Both the proposed methodology for PT definition and the alignment algorithm are generic to be applied on any clinical domain. We validated this solution for predicting CVD in patients with diabetes and we achieved a precision of 0.33, a recall of 0.72 and a specificity of 0.38. Therefore, the proposed solution in the diabetes use case can result of utmost utility to secondary screening.

Abstract: The decoupling of heavy fields as required by the Appelquist-Carazzone theorem plays a fundamental role in the construction of any effective field theory. However, it is not a trivial task to implement a renormalization prescription that produces the expected decoupling of massive fields, and it is even more difficult in curved spacetime. Focused on this idea, we consider the renormalization of the one-loop effective action for the Yukawa interaction with a background scalar field in curved space. We compute the beta functions within a generalized DeWitt-Schwinger subtraction procedure and discuss the decoupling in the running of the coupling constants. For the case of a quantized scalar field, all the beta function exhibit decoupling, including also the gravitational ones. For a quantized Dirac field, decoupling appears almost for all the beta functions. We obtain the anomalous result that the mass of the background scalar field does not decouple.

Abstract: We report on spectroscopic information and lifetime measurements in the neutron-rich I-135,I-137,I-139 isotopes. This is the first lifetime data on iodine isotopes beyond N = 82. Excited states were populated in fast neutron-induced fission of U-238 at the ALTO facility of IJCLab with the LICORNE neutron source and detected using the hybrid nu-ball spectrometer. The level schemes of the I-135,I-137,I-139 isotopes are revised in terms of excited states with up to maximum spin-parity of (33/2(+)), populated for the first time in fast neutron-induced fission. We provide first results on the lifetimes of the (9/2(1)(+)) and (13/2(1)(+)) states in I-137 and I-139, and the (17/2(1)(+)) state in 137I. In addition, we give upper lifetime limits for the (11/2(1)(+)) states in I135-139, the (15/2(1)(+)) state in I-137, the (17/2(1)(+)) state in I-139, and reexamine the (29/2(1)(+)) state in I-137. The isomeric data in I-13(5) are reinvestigated, such as the previously known (15/2(1)(+)) and (23/21) isomers with T-1/2 of 1.64(14) and 4.6(7) ns, respectively, as obtained in this work. The new spectroscopic information is compared to that from spontaneous or thermal-neutron induced fission and discussed in the context of large scale shell-model (LSSM) calculations for the region beyond Sn-132, indicating the behavior of collectivity for the three valence-proton iodine chain with N = 82, 84, 86.

Abstract: The vacuum expectation value v(s) of a Higgs triplet field Delta carrying two units of lepton number L induces neutrino masses alpha v(s). The neutral component of Delta gives rise to two Higgs particles, a pseudoscalar A and a scalar S. The most general renormalizable Higgs potential V for Delta and the Standard-Model Higgs doublet Phi does not permit the possibility that the mass of either A or S is small, of order v(s), while the other mass is heavy enough to forbid the decay Z -> AS to comply with LEP 1 data. We present a model with additional dimension-6 terms in V, in which this feature is absent and either A or S can be chosen light. Subsequently we propose the model as a remedy to cosmological anomalies, namely the tension between observed and predicted tensor-to-scalar mode ratios in the cosmic microwave background and the different values of the Hubble constant measured at different cosmological scales. Furthermore, if Delta dominantly couples to the third-generation doublet L-tau = (v(tau), tau), the deficit of v(tau) events at IceCube can be explained. The singly and doubly charged triplet Higgs bosons are lighter than 280 GeV and 400 GeV, respectively, and could be found at the LHC.