Records |
Author |
Etxebeste, A.; Barrio, J.; Bernabeu, J.; Lacasta, C.; Llosa, G.; Muñoz, E.; Ros, A.; Oliver, J.F. |
Title |
Study of sensitivity and resolution for full ring PET prototypes based on continuous crystals and analytical modeling of the light distribution |
Type |
Journal Article |
Year |
2019 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
Volume ![sorted by Volume (numeric) field, ascending order (up)](img/sort_asc.gif) |
64 |
Issue |
3 |
Pages |
035015 - 17pp |
Keywords |
continuous crystals; NEMA NU 4-2008; positron emission tomography (PET); Monte Carlo simulations; image reconstruction; depth of interaction |
Abstract |
Sensitivity and spatial resolution are the main parameters to maximize in the performance of a PET scanner. For this purpose, detectors consisting of a combination of continuous crystals optically coupled to segmented photodetectors have been employed. With the use of continuous crystals the sensitivity is increased with respect to the pixelated crystals. In addition, spatial resolution is no longer limited to the crystal size. The main drawback is the difficulty in determining the interaction position. In this work, we present the characterization of the performance of a full ring based on cuboid continuous crystals coupled to SiPMs. To this end, we have employed the simulations developed in a previous work for our experimental detector head. Sensitivity could be further enhanced by using tapered crystals. This enhancement is obtained by increasing the solid angle coverage, reducing the wedge-shaped gaps between contiguous detectors. The performance of the scanners based on both crystal geometries was characterized following NEMA NU 4-2008 standardized protocol in order to compare them. An average sensitivity gain over the entire axial field of view of 13.63% has been obtained with tapered geometry while similar performance of the spatial resolution has been proven with both scanners. The activity at which NECR and true peak occur is smaller and the peak value is greater for tapered crystals than for cuboid crystals. Moreover, a higher degree of homogeneity was obtained in the sensitivity map due to the tighter packing of the crystals, which reduces the gaps and results in a better recovery of homogeneous regions than for the cuboid configuration. Some of the results obtained, such as spatial resolution, depend on the interaction position estimation and may vary if other method is employed. |
Address |
[Etxebeste, Ane; Barrio, John; Bernabeu, Jose; Lacasta, Carlos; Llosa, Gabriela; Munoz, Enrique; Ros, Ana; Oliver, Josef F.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: ane.etxebeste@ific.uv.es |
Corporate Author |
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Thesis |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
|
Area |
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Expedition |
|
Conference |
|
Notes |
WOS:000457182500004 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
3897 |
Permanent link to this record |
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Author |
Barrientos, L.; Borja-Lloret, M.; Casaña, J.V.; Dendooven, P.; Garcia Lopez, J.G.; Hueso-Gonzalez, F.; Jiméeez-Ramos, M.C.; Perez-Curbelo, J.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G. |
Title |
Gamma-ray sources imaging and test-beam results with MACACO III Compton camera |
Type |
Journal Article |
Year |
2024 |
Publication |
Physica Medica |
Abbreviated Journal |
Phys. Medica |
Volume ![sorted by Volume (numeric) field, ascending order (up)](img/sort_asc.gif) |
117 |
Issue |
|
Pages |
103199 - 10pp |
Keywords |
Hadron therapy; Compton camera; Scintillator crystals; Silicon photomultipliers |
Abstract |
Hadron therapy is a radiotherapy modality which offers a precise energy deposition to the tumors and a dose reduction to healthy tissue as compared to conventional methods. However, methods for real-time monitoring are required to ensure that the radiation dose is deposited on the target. The IRIS group of IFIC-Valencia developed a Compton camera prototype for this purpose, intending to image the Prompt Gammas emitted by the tissue during irradiation. The system detectors are composed of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. After an initial characterization in the laboratory, in order to assess the system capabilities for future experiments in proton therapy centers, different tests were carried out in two facilities: PARTREC (Groningen, The Netherlands) and the CNA cyclotron (Sevilla, Spain). Characterization studies performed at PARTREC indicated that the detectors linearity was improved with respect to the previous version and an energy resolution of 5.2 % FWHM at 511 keV was achieved. Moreover, the imaging capabilities of the system were evaluated with a line source of 68Ge and a point-like source of 241Am-9Be. Images at 4.439 MeV were obtained from irradiation of a graphite target with an 18 MeV proton beam at CNA, to perform a study of the system potential to detect shifts at different intensities. In this sense, the system was able to distinguish 1 mm variations in the target position at different beam current intensities for measurement times of 1800 and 600 s. |
Address |
[Barrientos, L.; Borja-Lloret, M.; Casana, J. V.; Hueso-Gonzalez, F.; Perez-Curbelo, J.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Luis.Barrientos@ific.uv.es |
Corporate Author |
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Thesis |
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Publisher |
Elsevier Sci Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1120-1797 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
|
Notes |
WOS:001145147400001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
5892 |
Permanent link to this record |
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Author |
Barrientos, L.; Borja-Lloret, M.; Casana, J.V.; Hueso-Gonzalez, F.; Ros, A.; Roser, J.; Senra, C.; Solaz, C.; Viegas, R.; Llosa, G. |
Title |
System characterization and performance studies with MACACO III Compton camera |
Type |
Journal Article |
Year |
2023 |
Publication |
Radiation Physics and Chemistry |
Abbreviated Journal |
Radiat. Phys. Chem. |
Volume ![sorted by Volume (numeric) field, ascending order (up)](img/sort_asc.gif) |
208 |
Issue |
|
Pages |
110922 - 13pp |
Keywords |
Compton camera; Scintillator crystals; Silicon photomultipliers |
Abstract |
The IRIS group of IFIC-Valencia has developed a Compton camera prototype. The system detectors are made of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. Two models of silicon photomultipliers arrays with different micro pixel pitch (25 and 50 μm) have been chosen as possible candidates to improve the response of the new system. Characterization studies with a 22Na point-like source have indicated that the 25 μm photodetector provided better performance in terms of energy resolution (5.2% FWHM at 511 keV) and angular resolution (6.9 degrees FWHM at 1275 keV), and more stability with temperature variations. In addition, MACACO III imaging capabilities have been assessed using a structure composed of thirty-seven 22Na point-like sources. Furthermore, in order to evaluate possible ways of improving the system performance, several studies have been carried out by means of simulations both in realistic and performance improved conditions. In this work, the system performance is evaluated for its future application in different areas. |
Address |
[Barrientos, L.; Borja-Lloret, M.; Casana, J. V.; Hueso-Gonzalez, F.; Ros, A.; Roser, J.; Senra, C.; Solaz, C.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IF, Valencia, Spain, Email: Luis.Barrientos@ific.uv.es; |
Corporate Author |
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Thesis |
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Publisher |
Pergamon-Elsevier Science Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0969-806x |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
|
Notes |
WOS:000962800400001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
no |
Call Number |
IFIC @ pastor @ |
Serial |
5511 |
Permanent link to this record |
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Author |
Scandale, W et al; Lari, L. |
Title |
Deflection of high energy protons by multiple volume reflections in a modified multi-strip silicon deflector |
Type |
Journal Article |
Year |
2014 |
Publication |
Nuclear Instruments & Methods in Physics Research B |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. B |
Volume ![sorted by Volume (numeric) field, ascending order (up)](img/sort_asc.gif) |
338 |
Issue |
|
Pages |
108-111 |
Keywords |
Accelerator; Beam collimation; Crystal; Channeling; Volume reflection |
Abstract |
The effect of multiple volume reflections in one crystal was observed in each of several bent silicon strips for 400 GeV/c protons. This considerably increased the particle deflections. Some particles were also deflected due to channeling in one of the subsequent strips. As a result, the incident beam was strongly spread because of opposite directions of the deflections. A modified multi-strip deflector produced by periodic grooves on the surface of a thick silicon plate was used for these measurements. This technique provides perfect mutual alignment between crystal strips. Such multi-strip deflector may be effective for collider beam halo collimation and a study is planned at the CERN SPS circulating beam. |
Address |
[Scandale, W.; Arduini, G.; Butcher, M.; Cerutti, F.; Gilardoni, S.; Lari, L.; Lechner, A.; Losito, R.; Masi, A.; Mereghetti, A.; Metral, E.; Mirarchi, D.; Montesano, S.; Redaelli, S.; Schoofs, P.; Smirnov, G.] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland |
Corporate Author |
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Thesis |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-583x |
ISBN |
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Medium |
|
Area |
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Expedition |
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Conference |
|
Notes |
WOS:000343390400016 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
1974 |
Permanent link to this record |
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Author |
Llosa, G.; Barrio, J.; Lacasta, C.; Callier, S.; Raux, L.; de La Taille, C. |
Title |
First tests in the application of silicon photomultiplier arrays to dose monitoring in hadron therapy |
Type |
Journal Article |
Year |
2011 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
Volume ![sorted by Volume (numeric) field, ascending order (up)](img/sort_asc.gif) |
648 |
Issue |
|
Pages |
S96-S99 |
Keywords |
Hadron therapy; Compton imaging; LaBr3; Continuous crystal; SiPM; MPPC; G-APD |
Abstract |
A detector head composed of a continuous LaBr3 crystal coupled to a silicon photomultiplier array has been mounted and tested, for its use in a Compton telescope for dose monitoring in hadron therapy. The LaBr3 crystal has 16 mm x 18 mm x 5 mm size, and it is surrounded with reflecting material in five faces. The SiPM array has 16 (4 x 4) elements of 3 mm x 3 mm size. The SPIROC1 ASIC has been employed as readout electronics. The detector shows a linear behavior up to 1275 keV. The energy resolution obtained at 511 keV is 7% FWHM, and it varies as one over the square root of the energy up to the energies tested. The variations among the detector channels are within 12%. A preliminary measurement of the timing resolution gives 7 ns FWHM. The spatial resolution obtained with the center of gravity method is 1.2 mm FWHM. The tests performed confirm the correct functioning of the detector. |
Address |
[Llosa, G.; Barrio, J.; Lacasta, C.] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: gabriela.llosa@ific.uv.es |
Corporate Author |
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Thesis |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
|
ISSN |
0168-9002 |
ISBN |
|
Medium |
|
Area |
|
Expedition |
|
Conference |
|
Notes |
WOS:000305376900026 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
1068 |
Permanent link to this record |