Abstract: Compton cameras can offer advantages over gamma cameras for some applications, since they are well suited for multitracer imaging and for imaging high-energy radiotracers, such as those employed in radionuclide therapy. While in conventional clinical settings state-of-the-art Compton cameras cannot compete with well-established methods such as PET and SPECT, there are specific scenarios in which they can constitute an advantageous alternative. The combination of PET and Compton imaging can benefit from the improved resolution and sensitivity of current PET technology and, at the same time, overcome PET limitations in the use of multiple radiotracers. Such a system can provide simultaneous assessment of different radiotracers under identical conditions and reduce errors associated with physical factors that can change between acquisitions. Advances are being made both in instrumentation developments combining PET and Compton cameras for multimodal or three-gamma imaging systems, and in image reconstruction, addressing the challenges imposed by the combination of the two modalities or the new techniques. This review article summarizes the advances made in Compton cameras for medical imaging and their combination with PET.

Abstract: We study the energy loss of excited monopolium in an atomic medium. We perform a classical calculation in line with a similar calculation performed for charged particles which leads in the non-relativistic limit to the Bethe-Bloch formula except for the density dependence of the medium, which we do not consider in this paper. Our result shows that for maximally deformed Rydberg states, the ionization of monopolium in a light atomic medium is similar to that of light ions.

Abstract: We report on a hybrid in-beam PET and prompt-gamma Compton imaging system aimed at quasi real-time ion-range verification in proton-therapy treatments. Proof-of-concept experiments were carried out at the radiobiology beam line of the CNA cyclotron facility using a set of two synchronous Compton imagers and different target materials. The time structure of the 18 MeV proton beam was shaped with a series of beam-on and beam-off intervals, thereby mimicking a pulsed proton beam on a long time scale. During beam-on intervals, Compton imagingwas performed utilizing the high energy. -rays promptly emitted from the nuclear reactions occurring in the targets. In the course of the beam-off intervals in situ positron-emission tomography was accomplished with the same imagers using the beta+ decay of activated nuclei. The targets used were stacks of different materials covering also various proton ranges and energies. A systematic study on the performance of these two complementary imaging techniques is reported and the experimental results interpreted on the basis ofMonte Carlo calculations. The results demonstrate the possibility to combine both imaging techniques in a concomitant way, where high-efficiency prompt-gamma imaging is complemented with the high spatial accuracy of PET. Empowered by these results we suggest that a pulsed beam with a suitable duty cycle, in conjunction with in situ Compton- and PET-imaging may help to attain complementary information and quasi real-time range monitoring with high accuracy.

Abstract: We present a detailed study of the lowest-lying 1/2(-) and 3/2(-) Lambda Q resonances both in the heavy 2 2 quark (bottom and charm) and the strange sectors. We have paid special attention to the interplay between the constituent quark-model and chiral baryon-meson degrees of freedom, which are coupled using a unitarized scheme consistent with leading-order heavy quark symmetries. We show that the Lambda(b)(5912) [J(P) = 1/2(-)], Lambda(b)(5920) [J(P) = 3/2(-)] and the Lambda(c)(2625) [J(P) = 3/2-], and the Lambda(1520) [J(P) = 3/2(-)] admitting larger breaking corrections, are heavyquark spin-flavor siblings. They can be seen as dressed quark-model states with Sigma Q(()*()) pi molecular components of the order of 30%. The J(P)=1(-) Lambda(2595) has, however, a higher molecular 2 probability of at least 50%, and even values greater than 70% can be easily accommodated. This is because it is located almost on top of the threshold of the Sigma(c)pi pair, which largely influences its properties. Although the light degrees of freedom in this resonance would be coupled to spin-parity 1(-) as in the Lambda(b)(5912), Lambda(b)(5920) and Lambda(c)(2625), the Lambda(c)(2595) should not be considered as a heavy-quark spin-flavor partner of the former ones. We also show that the Lambda(1405) chiral two-pole pattern does not have analogs in the 1 – charmed and bottomed sectors, because the 2 N D-(*()) and N (B) over bar (()*()) channels do not play for heavy quarks the decisive role that the N (K) over bar does in the strange sector, and the notable influence of the bare quark-model states for the charm and bottom resonances. Finally, we predict the existence of two Lambda(b)(6070) and two Lambda(c)(2765) heavy-quark spin and flavor sibling odd parity states.

Abstract: We propose a generalized Kim-Shifman-Vainshtein-Zakharov-type axion framework in which colored fermions and scalars act as two -loop Majorana neutrino -mass mediators. The global Peccei-Quinn symmetry under which exotic fermions are charged solves the strong CP problem. Within our general proposal, various setups can be distinguished by probing the axion-to-photon coupling at helioscopes and haloscopes. We also comment on axion dark -matter production in the early Universe.