Records |
Author |
Torres-Espallardo, I.; Diblen, F.; Rohling, H.; Solevi, P.; Gillam, J.; Watts, D.; Espana, S.; Vandenberghe, S.; Fiedler, F.; Rafecas, M. |
Title |
Evaluation of resistive-plate-chamber-based TOF-PET applied to in-beam particle therapy monitoring |
Type |
Journal Article |
Year |
2015 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
Volume ![sorted by Volume (numeric) field, descending order (down)](img/sort_desc.gif) |
60 |
Issue |
9 |
Pages |
N187-N208 |
Keywords |
PET; in-beam; RPC; particle therapy; TOF; range deviation; partial-ring |
Abstract |
Particle therapy is a highly conformal radiotherapy technique which reduces the dose deposited to the surrounding normal tissues. In order to fully exploit its advantages, treatment monitoring is necessary to minimize uncertainties related to the dose delivery. Up to now, the only clinically feasible technique for the monitoring of therapeutic irradiation with particle beams is Positron Emission Tomography (PET). In this work we have compared a Resistive Plate Chamber (RPC)-based PET scanner with a scintillation-crystal-based PET scanner for this application. In general, the main advantages of the RPC-PET system are its excellent timing resolution, low cost, and the possibility of building large area systems. We simulated a partial-ring scannerbeam monitoring, which has an intrinsically low positron yield compared to diagnostic PET. In addition, for in-beam PET there is a further data loss due to the partial ring configuration. In order to improve the performance of the RPC-based scanner, an improved version of the RPC detector (modifying the thickness of the gas and glass layers), providing a larger sensitivity, has been simulated and compared with an axially extended version of the crystal-based device. The improved version of the RPC shows better performance than the prototype, but the extended version of the crystal-based PET outperforms all other options. based on an RPC prototype under construction within the Fondazione per Adroterapia Oncologica (TERA). For comparison with the crystal-based PET scanner we have chosen the geometry of a commercially available PET scanner, the Philips Gemini TF. The coincidence time resolution used in the simulations takes into account the current achievable values as well as expected improvements of both technologies. Several scenarios (including patient data) have been simulated to evaluate the performance of different scanners. Initial results have shown that the low sensitivity of the RPC hampers its application to hadron |
Address |
[Torres-Espallardo, I.; Solevi, P.; Gillam, J.; Rafecas, M.] UV, CSIC, Inst Fis Corpuscular IFIC, E-46071 Valencia, Spain, Email: irene.torres@uv.es |
Corporate Author |
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Thesis |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000354104700003 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
2227 |
Permanent link to this record |
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Author |
Solevi, P.; Magrin, G.; Moro, D.; Mayer, R. |
Title |
Monte Carlo study of microdosimetric diamond detectors |
Type |
Journal Article |
Year |
2015 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
Volume ![sorted by Volume (numeric) field, descending order (down)](img/sort_desc.gif) |
60 |
Issue |
18 |
Pages |
7069-7083 |
Keywords |
ion-beam therapy; microdosimetry; diamonds; GATE |
Abstract |
Ion-beam therapy provides a high dose conformity and increased radiobiological effectiveness with respect to conventional radiation-therapy. Strict constraints on the maximum uncertainty on the biological weighted dose and consequently on the biological weighting factor require the determination of the radiation quality, defined as the types and energy spectra of the radiation at a specific point. However the experimental determination of radiation quality, in particular for an internal target, is not simple and the features of ion interactions and treatment delivery require dedicated and optimized detectors. Recently chemical vapor deposition (CVD) diamond detectors have been suggested as ion-beam therapy microdosimeters. Diamond detectors can be manufactured with small cross sections and thin shapes, ideal to cope with the high fluence rate. However the sensitive volume of solid state detectors significantly deviates from conventional microdosimeters, with a diameter that can be up to 1000 times the height. This difference requires a redefinition of the concept of sensitive thickness and a deep study of the secondary to primary radiation, of the wall effects and of the impact of the orientation of the detector with respect to the radiation field. The present work intends to study through Monte Carlo simulations the impact of the detector geometry on the determination of radiation quality quantities, in particular on the relative contribution of primary and secondary radiation. The dependence of microdosimetric quantities such as the unrestricted linear energy L and the lineal energy y are investigated for different detector cross sections, by varying the particle type (carbon ions and protons) and its energy. |
Address |
[Solevi, Paola; Magrin, Giulio; Mayer, Ramona] EBG MedAustron, A-2700 Wiener Neustadt, Austria, Email: paola.solevi@ovgu.de |
Corporate Author |
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Thesis |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000361124000004 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
2379 |
Permanent link to this record |
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Author |
n_TOF Collaboration (Guerrero, C. et al); Giubrone, G.; Tain, J.L. |
Title |
Characterization of the New n_TOF Neutron Beam: Fluence, Profile and Resolution |
Type |
Journal Article |
Year |
2011 |
Publication |
Journal of the Korean Physical Society |
Abbreviated Journal |
J. Korean Phys. Soc. |
Volume ![sorted by Volume (numeric) field, descending order (down)](img/sort_desc.gif) |
59 |
Issue |
2 |
Pages |
1624-1627 |
Keywords |
n_TOF; Time-of-flight; Neutron beam; Nuclear data; Cross sections |
Abstract |
After a halt of four years, the nTOF spallation neutron facility at CERN has resumed operation in November 2008 with a new spallation target characterized by an improved safety and engineering design, resulting in a more robust overall performance and efficient cooling. The first measurement during the 2009 run has aimed at the full characterization of the neutron beam. Several detectors, such as calibrated fission chambers, the nTOF Silicon Monitor, a MicroMegas detector with (10)B and (235)U samples, as well as liquid and solid scintillators have been used in order to characterize the properties of the neutron fluence. The spatial profile of the beam has been studied with a specially designed “X-Y” MicroMegas which provided a 2D image of the beam as a function of neutron energy. Both properties have been compared with simulations performed. with the FLUKA code. The characterization of the resolution function is based on results from simulations which have been verified by the study of narrow capture resonances. of (56)Fe, which were measured as part of a new campaign of (n,gamma) measurements on Fe and Ni isotopes. |
Address |
[Guerrero, C; Becares, V; Cano-Ott, D; Fernandez-Ordonez, M; Gonzalez-Romero, E; Martin-Fuertes, F; Martinez, T; Mendoza, E; Pina, G; Quinones, J; Vlachoudis, V] Ctr Invest Energet Medioambientales & Tecnol, Madrid 28040, Spain, Email: carlos.guerrero@ciemat.es |
Corporate Author |
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Thesis |
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Publisher |
Korean Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0374-4884 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000294080700041 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ elepoucu @ |
Serial |
735 |
Permanent link to this record |
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Author |
Piersanti, L.; Bellini, F.; Bini, F.; Collamati, F.; De Lucia, E.; Durante, M.; Faccini, R.; Ferroni, F.; Fiore, S.; Iarocci, E.; La Tessa, C.; Marafini, M.; Mattei, I.; Patera, V.; Ortega, P.G.; Sarti, A.; Schuy, C.; Sciubba, A.; Vanstalle, M.; Voena, C. |
Title |
Measurement of charged particle yields from PMMA irradiated by a 220 MeV/u C-12 beam |
Type |
Journal Article |
Year |
2014 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
Volume ![sorted by Volume (numeric) field, descending order (down)](img/sort_desc.gif) |
59 |
Issue |
7 |
Pages |
1857-1872 |
Keywords |
drift chamber; LYSO; hadrontherapy; carbon ion beam; dose monitoring |
Abstract |
The radiation used in hadrontherapy treatments interacts with the patient body producing secondary particles, either neutral or charged, that can be used for dose and Bragg peak monitoring and to provide a fast feedback on the treatment plans. Recent results obtained from the authors on simplified setups (mono-energetic primary beams interacting with homogeneous tissue like target) have already indicated the correlation that exists between the flux of these secondaries coming from the target (e.g. protons and photons) and the position of the primary beam Bragg peak. In this paper, the measurements of charged particle fluxes produced by the interaction of a 220 MeV/u carbon ion beam at GSI, Darmstadt, with a polymethyl methacrylate target are reported. The emission region of protons (p), deuterons (d) and tritons (t) has been characterized using a drift chamber while the particle time-of-flight, used to compute the kinetic energy spectra, was measured with a LYSO scintillator.The energy released in the LYSO crystal was used for particle identification purposes. The measurements were repeated with the setup at 60 degrees and 90 degrees with respect to the primary beam direction. The accuracy on the fragments emission profile reconstruction and its relationship with the Bragg peak position have been studied. Based on the acquired experimental evidence, a method to monitor the dose profile and the position of the Bragg peak inside the target is proposed. |
Address |
[Piersanti, L.; De Lucia, E.; Iarocci, E.; Mattei, I.; Sarti, A.] Ist Nazl Fis Nucl, Lab Nazl Frascati, I-00044 Frascati, Italy, Email: vincenzo.patera@lnf.infn.it |
Corporate Author |
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Thesis |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000333186200020 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
1735 |
Permanent link to this record |
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Author |
Martin-Luna, P.; Gimeno, B.; Gonzalez-Iglesias, D.; Esperante, D.; Blanch, C.; Fuster-Martinez, N.; Martinez-Reviriego, P.; Fuster, J. |
Title |
On the Magnetic Field of a Finite Solenoid |
Type |
Journal Article |
Year |
2023 |
Publication |
IEEE Transactions on Magnetics |
Abbreviated Journal |
IEEE Trans. Magn. |
Volume ![sorted by Volume (numeric) field, descending order (down)](img/sort_desc.gif) |
59 |
Issue |
4 |
Pages |
7000106 - 6pp |
Keywords |
Solenoids; Magnetic fields; Integral equations; Magnetostatics; Magnetostatic waves; Particle beams; NASA; Elliptic integrals; finite solenoid; magnetostatics |
Abstract |
The magnetostatic field of a finite solenoid with infinitely thin walls carrying a dc current oriented in the azimuthal direction is calculated everywhere in space in terms of complete elliptic integrals by direct integration of the Biot-Savart law. The solution is particularized near the solenoid axis and in the midplane perpendicular to the axis obtaining expressions that agree with some typical approximations that are made in introductory courses of electromagnetism or in the technical literature. The range of validity of these approximations has been studied comparing them with the obtained general expression. |
Address |
[Martin-Luna, P.; Gimeno, B.; Gonzalez-Iglesias, D.; Esperante, D.; Blanch, C.; Fuster-Martinez, N.; Martinez-Reviriego, P.; Fuster, J.] Univ Valencia, Inst Corpuscular Phys IFIC, CSIC, Paterna 46980, Spain, Email: Pablo.Martin@uv.es |
Corporate Author |
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Thesis |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0018-9464 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001006992700005 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
no |
Call Number |
IFIC @ pastor @ |
Serial |
5552 |
Permanent link to this record |