Abstract: Generally, the dynamics of test particles around galaxies, as well as the corresponding mass deficit, is explained by postulating the existence of a hypothetical dark matter. In fact, the behavior of the rotation curves shows the existence of a constant velocity region, near the baryonic matter distribution, followed by a quick decay at large distances. In this work, we consider the possibility that the behavior of the rotational velocities of test particles gravitating around galaxies can be explained within the framework of the recently proposed hybrid metric-Palatini gravitational theory. The latter is constructed by modifying the metric Einstein-Hilbert action with an f(R) term in the Palatini formalism. It was shown that the theory unifies local constraints and the late-time cosmic acceleration, even if the scalar field is very light. In the intermediate galactic scale, we show explicitly that in the hybrid metric-Palatini model the tangential velocity can be explicitly obtained as a function of the scalar field of the equivalent scalar-tensor description. The model predictions are compared model with a small sample of rotation curves of low surface brightness galaxies, respectively, and a good agreement between the theoretical rotation Curves and the observational data is found. The possibility of constraining the form of the scalar field and the parameters of the model by using the stellar velocity dispersions is also analyzed. Furthermore, the Doppler velocity shifts are also obtained in terms of the scalar field. All the physical and geometrical quantities and the numerical parameters in the hybrid metric-Palatini model can be expressed in terms of observable/measurable parameters, such as the tangential velocity, the baryonic mass of the galaxy, the Doppler frequency shifts, and the stellar dispersion velocity, respectively. Therefore, the obtained results open the possibility of testing the hybrid metric-Palatini gravitational models at the galactic or extra-galactic scale by using direct astronomical and astrophysical observations.

Abstract: We study the interaction between two B = 1 states in a chiral soliton model where baryons are described as non-topological solitons. By using the hedgehog solution for the B = 1 states we construct three possible B = 2 configurations to analyze the role of the relative orientation of the hedgehog quills in the dynamics. The strong dependence of the intersoliton interaction on these relative orientations reveals that studies of dense hadronic matter using this model should take into account their implications.

Abstract: The European PARTNER project developed a prototypical system for sharing hadron therapy data. This system allows doctors and patients to record and report treatment-related events during and after hadron therapy. It presents doctors and statisticians with an integrated view of adverse events across institutions, using open-source components for data federation, semantics, and analysis. There is a particular emphasis upon semantic consistency, achieved through intelligent, annotated form designs. The system as presented is ready for use in a clinical setting, and amenable to further customization. The essential contribution of the work reported here lies in the novel data integration and reporting methods, as well as the approach to software sustainability achieved through the use of community-supported open-source components.

Abstract: In the development of prototype systems for positron emission tomography a valid and robust image reconstruction algorithm is required. However, prototypes often employ novel detector and system geometries which may change rapidly under optimization. In addition, developing systems generally produce highly granular, or possibly continuous detection domains which require some level of on-the-fly calculation for retention of measurement precision. In this investigation a new method of on-the-fly system matrix calculation is proposed that provides advantages in application to such list-mode systems in terms of flexibility in system modeling. The new method is easily adaptable to complicated system geometries and available computational resources. Detection uncertainty models are used as random number generators to produce ensembles of possible photon trajectories at image reconstruction time for each datum in the measurement list. However, the result of this approach is that the system matrix elements change at each iteration in a non-repetitive manner. The resulting algorithm is considered the simulation of a one-pass list (SOPL) which is generated and the list traversed during image reconstruction. SOPL alters the system matrix in use at each iteration and so behavior within the maximum likelihood-expectation maximization algorithm was investigated. A two-pixel system and a small two dimensional imaging model are used to illustrate the process and quantify aspects of the algorithm. The two-dimensional imaging system showed that, while incurring a penalty in image resolution, in comparison to a non-random equal-computation counterpart, SOPL provides much enhanced noise properties. In addition, enhancement in system matrix quality is straightforward (by increasing the number of samples in the ensemble) so that the resolution penalty can be recovered when desired while retaining improvement in noise properties. Finally the approach is tested and validated against a standard (highly accurate) system matrix using experimental data from a prototype system-the AX-PET.

Abstract: AX-PET is a novel PET detector based on axially oriented crystals and orthogonal wavelength shifter (WLS) strips, both individually read out by silicon photo-multipliers. Its design decouples sensitivity and spatial resolution, by reducing the parallax error due to the layered arrangement of the crystals. Additionally the granularity of AX-PET enhances the capability to track photons within the detector yielding a large fraction of inter-crystal scatter events. These events, if properly processed, can be included in the reconstruction stage further increasing the sensitivity. Its unique features require dedicated Monte-Carlo simulations, enabling the development of the device, interpreting data and allowing the development of reconstruction codes. At the same time the non-conventional design of AX-PET poses several challenges to the simulation and modeling tasks, mostly related to the light transport and distribution within the crystals and WLS strips, as well as the electronics readout. In this work we present a hybrid simulation tool based on an analytical model and a Monte-Carlo based description of the AX-PET demonstrator. It was extensively validated against experimental data, providing excellent agreement.