Abstract: Nowadays, the options available to perform external dosimetric audits of the high dose rate (HDR) brachytherapy treatment process are limited. In this work, we present a methodology that allows for performing dosimetric audits in this field. A phantom was designed and manufactured for this purpose. The criteria for its design, together with the in-house measurements for its characterization, are presented. The result is a user-friendly system that can be mailed to perform dosimetric audits in HDR brachytherapy on-site for systems using either Iridium-192 (Ir-192) or Cobalt-60 (Co-60) sources. Objectives: The main goal of this work is to design and characterize a user-friendly methodology to perform mailed dosimetric audits in high dose rate (HDR) brachytherapy for systems using either Iridium-192 (Ir-192) or Cobalt-60 (Co-60) sources. Methods: A solid phantom was designed and manufactured with four catheters and a central slot to place one dosimeter. Irradiations with an Elekta MicroSelectron V2 for Ir-192, and with a BEBIG Multisource for Co-60 were performed for its characterization. For the dose measurements, nanoDots, a type of optically stimulated luminescent dosimeters (OSLDs), were characterized. Monte Carlo (MC) simulations were performed to evaluate the scatter conditions of the irradiation set-up and to study differences in the photon spectra of different Ir-192 sources (Microselectron V2, Flexisource, BEBIG Ir2.A85-2 and Varisource VS2000) reaching the dosimeter in the irradiation set-up. Results: MC simulations indicate that the surface material on which the phantom is supported during the irradiations does not affect the absorbed dose in the nanoDot. Generally, differences below 5% were found in the photon spectra reaching the detector when comparing the Microselectron V2, the Flexisource and the BEBIG models. However, differences up to 20% are observed between the V2 and the Varisource VS2000 models. The calibration coefficients and the uncertainty in the dose measurement were evaluated. Conclusions: The system described here is able to perform dosimetric audits in HDR brachytherapy for systems using either Ir-192 or Co-60 sources. No significant differences are observed between the photon spectra reaching the detector for the MicroSelectron V2, the Flexisource and the BEBIG Ir-192 sources. For the Varisource VS2000, a higher uncertainty is considered in the dose measurement to allow for the nanoDot response.

Abstract: We present a new algorithm for anomaly detection called Anomaly Awareness. The algorithm learns about normal events while being made aware of the anomalies through a modification of the cost function. We show how this method works in different Particle Physics situations and in standard Computer Vision tasks. For example, we apply the method to images from a Fat Jet topology generated by Standard Model Top and QCD events, and test it against an array of new physics scenarios, including Higgs production with EFT effects and resonances decaying into two, three or four subjets. We find that the algorithm is effective identifying anomalies not seen before, and becomes robust as we make it aware of a varied-enough set of anomalies.

Abstract: We report on recent experimental results on beta decay into self-conjugate ( N = Z) nuclei with mass number 58 <= A <= 70. Super-allowed b decays from the J(pi) = 0(+) ground state of a Z = N + 2 parent nucleus are to the isobaric analogue state through so-called Fermi transitions and to J(pi) = 1(+) states by way of Gamow-Teller (GT) transitions. The operator of the latter decay is a generator of Wigner's SU(4) algebra and as a consequence GT transitions obey selection rules associated with this symmetry. Since SU(4) is progressively broken with increasing A, mainly as a consequence of the spinorbit interaction, this symmetry is not relevant for the nuclei considered here. We argue, however, that the pseudo-spin-orbit splitting can be small in nuclei with 58 <= A <= 70, in which case nuclear states exhibit an approximate pseudo-SU(4) symmetry. To test this conjecture, GT decay strength is calculated with use of a schematic Hamiltonian with pseudo-SU(4) symmetry. Some generic features of the GT beta decay due to pseudo-SU(4) symmetry are pointed out. The experimentally observed GT strength indicates a restoration of pseudo-SU(4) symmetry for A = 70.