Otal, A., Celada, F., Chimeno, J., Vijande, J., Pellejero, S., Perez-Calatayud, M. J., et al. (2022). Review on Treatment Planning Systems for Cervix Brachytherapy (Interventional Radiotherapy): Some Desirable and Convenient Practical Aspects to Be Implemented from Radiation Oncologist and Medical Physics Perspectives. Cancers, 14(14), 3467–15pp.
Abstract: Simple Summary There are no brachytherapy treatment planning systems (TPS) exclusively for the treatment of cervical tumours, so general-purpose TPSs are used. However, these treatments have some particular features concerning the treatment of other pathologies, especially in the case of exclusive use of MRI as an imaging modality and the presence of gynaecological applicators in combination with an interstitial part. That is why it is essential to review the latest versions of commercial TPSs to find the potential features to improve with the help of a group of experimented medical physicists and radiation oncologists. Furthermore, after reviewing the recent literature for advances applicable to cervical brachytherapy and through his own clinical experience, possible improvements are proposed to software providers for the development of new tools. Intracavitary brachytherapy (BT, Interventional Radiotherapy, IRT), plays an essential role in the curative intent of locally advanced cervical cancer, for which the conventional approach involves external beam radiotherapy with concurrent chemotherapy followed by BT. This work aims to review the different methodologies used by commercially available treatment planning systems (TPSs) in exclusive magnetic resonance imaging-based (MRI) cervix BT with interstitial component treatments. Practical aspects and improvements to be implemented into the TPSs are discussed. This review is based on the clinical expertise of a group of radiation oncologists and medical physicists and on interactive demos provided by the software manufacturers. The TPS versions considered include all the new tools currently in development for future commercial releases. The specialists from the supplier companies were asked to propose solutions to some of the challenges often encountered in a clinical environment through a questionnaire. The results include not only such answers but also comments by the authors that, in their opinion, could help solve the challenges covered in these questions. This study summarizes the possibilities offered nowadays by commercial TPSs, highlighting the absence of some useful tools that would notably improve the planning of MR-based interstitial component cervix brachytherapy.
|
Navarro-Salas, J., & Pla, S. (2022). Particle Creation and the Schwinger Model. Symmetry-Basel, 14(11), 2435–9pp.
Abstract: We study the particle creation process in the Schwinger model coupled with an external classical source. One can approach the problem by taking advantage of the fact that the full quantized model is solvable and equivalent to a (massive) gauge field with a non-local effective action. Alternatively, one can also face the problem by following the standard semiclassical route. This means quantizing the massless Dirac field and considering the electromagnetic field as a classical background. We evaluate the energy created by a generic, homogeneous, and time-dependent source. The results match exactly in both approaches. This proves in a very direct and economical way the validity of the semiclassical approach for the (massless) Schwinger model, in agreement with a previous analysis based on the linear response equation. Our discussion suggests that a similar analysis for the massive Schwinger model could be used as a non-trivial laboratory to confront a fully quantized solvable model with its semiclassical approximation, therefore mimicking the long-standing confrontation of quantum gravity with quantum field theory in curved spacetime.
|
Ramirez-Uribe, S., Hernandez-Pinto, R. J., Rodrigo, G., & Sborlini, G. F. R. (2022). From Five-Loop Scattering Amplitudes to Open Trees with the Loop-Tree Duality. Symmetry-Basel, 14(12), 2571–14pp.
Abstract: Characterizing multiloop topologies is an important step towards developing novel methods at high perturbative orders in quantum field theory. In this article, we exploit the Loop-Tree Duality (LTD) formalism to analyse multiloop topologies that appear for the first time at five loops. Explicitly, we open the loops into connected trees and group them according to their topological properties. Then, we identify a kernel generator, the so-called N7MLT universal topology, that allows us to describe any scattering amplitude of up to five loops. Furthermore, we provide factorization and recursion relations that enable us to write these multiloop topologies in terms of simpler subtopologies, including several subsets of Feynman diagrams with an arbitrary number of loops. Our approach takes advantage of many symmetries present in the graphical description of the original fundamental five-loop topologies. The results obtained in this article might shed light into a more efficient determination of higher-order corrections to the running couplings, which are crucial in the current and future precision physics program.
|
DUNE Collaboration(Abud, A. A. et al), Antonova, M., Barenboim, G., Cervera-Villanueva, A., De Romeri, V., Fernandez Menendez, P., et al. (2022). Design, construction and operation of the ProtoDUNE-SP Liquid Argon TPC. J. Instrum., 17(1), P01005–111pp.
Abstract: The ProtoDUNE-SP detector is a single-phase liquid argon time projection chamber (LArTPC) that was constructed and operated in the CERN North Area at the end of the H4 beamline. This detector is a prototype for the first far detector module of the Deep Underground Neutrino Experiment (DUNE), which will be constructed at the Sandford Underground Research Facility (SURF) in Lead, South Dakota, U.S.A. The ProtoDUNE-SP detector incorporates full-size components as designed for DUNE and has an active volume of 7 x 6 x 7.2 m3. The H4 beam delivers incident particles with well-measured momenta and high-purity particle identification. ProtoDUNE-SP's successful operation between 2018 and 2020 demonstrates the effectiveness of the single-phase far detector design. This paper describes the design, construction, assembly and operation of the detector components.
Keywords: Noble liquid detectors (scintillation, ionization, double-phase); Photon detectors for UV; visible and IR photons (solid-state) (PIN diodes, APDs, Si-PMTs, G-APDs, CCDs, EBCCDs, EMCCDs, CMOS imagers, etc); Scintillators; scintillation and light emission processes (solid, gas and liquid scintillators); Time projection Chambers (TPC)
|
ATLAS Collaboration(Aad, G. et al), Amos, K. R., Aparisi Pozo, J. A., Bailey, A. J., Cabrera Urban, S., Cardillo, F., et al. (2022). Operation and performance of the ATLAS semiconductor tracker in LHC Run 2. J. Instrum., 17(1), P01013–56pp.
Abstract: The semiconductor tracker (SCT) is one of the tracking systems for charged particles in the ATLAS detector. It consists of 4088 silicon strip sensor modules. During Run 2 (2015-2018) the Large Hadron Collider delivered an integrated luminosity of 156 fb(-1) to the ATLAS experiment at a centre-of-mass proton-proton collision energy of 13 TeV. The instantaneous luminosity and pile-up conditions were far in excess of those assumed in the original design of the SCT detector. Due to improvements to the data acquisition system, the SCT operated stably throughout Run 2. It was available for 99.9% of the integrated luminosity and achieved a data-quality efficiency of 99.85%. Detailed studies have been made of the leakage current in SCT modules and the evolution of the full depletion voltage, which are used to study the impact of radiation damage to the modules. '
|
