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Author Piriz, G.H.; Gonzalez-Sprinberg, G.A.; Ballester, F.; Vijande, J. doi  openurl
  Title Dosimetry of Large Field Valencia applicators for Cobalt-60-based brachytherapy Type Journal Article
  Year 2024 Publication Medical Physics Abbreviated Journal Med. Phys.  
  Volume (up) Issue Pages 5pp  
  Keywords dosimetry; Monte Carlo; skin brachytherapy; Valencia applicators  
  Abstract BackgroundNon-melanoma skin cancer is one of the most common types of cancer and one of the main approaches is brachytherapy. For small lesions, the treatment of this cancer with brachytherapy can be done with two commercial applicators, one of these is the Large Field Valencia Applicators (LFVA).PurposeThe aim of this study is to test the capabilities of the LFVA to use clinically 60Co sources instead of the 192Ir ones. This study was designed for the same dwell positions and weights for both sources.MethodsThe Penelope Monte Carlo code was used to evaluate dose distribution in a water phantom when a 60Co source is considered. The LFVA design and the optimized dwell weights reported for the case of 192Ir are maintained with the only exception of the dwell weight of the central position, that was increased. 2D dose distributions, field flatness, symmetry and the leakage dose distribution around the applicator were calculated.ResultsWhen comparing the dose distributions of both sources, field flatness and symmetry remain unchanged. The only evident difference is an increase of the penumbra regions for all depths when using the 60Co source. Regarding leakage, the maximum dose within the air volume surrounding the applicator is in the order of 20% of the prescription dose for the 60Co source, but it decreases to less than 5% at about 1 cm distance.ConclusionsFlatness and symmetry remains unaltered as compared with 192Ir sources, while an increase in leakage has been observed. This proves the feasibility of using the LFVA in a larger range of clinical applications.  
  Address [Piriz, Gustavo H.; Gonzalez-Sprinberg, Gabriel A.] Univ Republica, Fac Sci, Med Phys Unit, Montevideo, Uruguay, Email: ghpiriz@gmail.com  
  Corporate Author Thesis  
  Publisher Wiley Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0094-2405 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001187737100001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 6011  
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Author Asai, M.; Cortes-Giraldo, M.A.; Gimenez-Alventosa, V.; Gimenez, V.; Salvat, F. doi  openurl
  Title The PENELOPE Physics Models and Transport Mechanics. Implementation into Geant4 Type Journal Article
  Year 2021 Publication Frontiers in Physics Abbreviated Journal Front. Physics  
  Volume (up) 9 Issue Pages 738735 - 20pp  
  Keywords coupled electron-photon transport; Monte Carlo simulation; PENELOPE code system; random-hinge method; Geant4 toolkit  
  Abstract A translation of the penelope physics subroutines to C++, designed as an extension of the Geant4 toolkit, is presented. The Fortran code system penelope performs Monte Carlo simulation of coupled electron-photon transport in arbitrary materials for a wide energy range, nominally from 50 eV up to 1 GeV. Penelope implements the most reliable interaction models that are currently available, limited only by the required generality of the code. In addition, the transport of electrons and positrons is simulated by means of an elaborate class II scheme in which hard interactions (involving deflection angles or energy transfers larger than pre-defined cutoffs) are simulated from the associated restricted differential cross sections. After a brief description of the interaction models adopted for photons and electrons/positrons, we describe the details of the class-II algorithm used for tracking electrons and positrons. The C++ classes are adapted to the specific code structure of Geant4. They provide a complete description of the interactions and transport mechanics of electrons/positrons and photons in arbitrary materials, which can be activated from the G4ProcessManager to produce simulation results equivalent to those from the original penelope programs. The combined code, named PenG4, benefits from the multi-threading capabilities and advanced geometry and statistical tools of Geant4.  
  Address [Asai, Makoto] SLAC Natl Accelerator Lab, Menlo Pk, CA USA, Email: miancortes@us.es;  
  Corporate Author Thesis  
  Publisher Frontiers Media Sa Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2296-424x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000742889400001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5080  
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Author Campanario, F.; Kubocz, M. url  doi
openurl 
  Title Higgs boson CP-properties of the gluonic contributions in Higgs plus three jet production via gluon fusion at the LHC Type Journal Article
  Year 2014 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.  
  Volume (up) 10 Issue 10 Pages 173 - 16pp  
  Keywords QCD Phenomenology; Monte Carlo Simulations  
  Abstract in high energy hadronic collisions, a general CP-violating Higgs boson Phi with accompanying jets can be efficiently produced via gluon fusion, which is mediated by heavy quark loops. In this article, we study the dominant sub-channel gg -> ggg Phi of the gluon fusion production process with triple real emission corrections at order alpha(5)(s). We go beyond the heavy top-quark approximation and include the full mass dependence of the top- and bottom-quark contributions. Furthermore, in a specific model we demonstrate the features of our program and show the impact of bottom-quark loop contributions in combination with large values of tan beta on differential distributions sensitive to CP-rneasurements of the Higgs boson.  
  Address [Campanario, Francisco] Univ Valencia CSIC, IFIC, Div Theory, E-46100 Valencia, Spain, Email: francisco.campanario@ific.uv.es;  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1029-8479 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000344652800003 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2007  
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Author Oliver, S.; Gimenez-Alventosa, V.; Berumen, F.; Gimenez, V.; Beaulieu, L.; Ballester, F.; Vijande, J. doi  openurl
  Title Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy Type Journal Article
  Year 2023 Publication Zeitschrift für Medizinische Physik Abbreviated Journal Z. Med. Phys.  
  Volume (up) 33 Issue 4 Pages 511-528  
  Keywords Monte Carlo; PenRed; Brachytherapy; DICOM; Medical physics  
  Abstract Purpose: The purpose of this study is to validate the PenRed Monte Carlo framework for clinical applications in brachytherapy. PenRed is a C++ version of Penelope Monte Carlo code with additional tallies and utilities. Methods and materials: Six benchmarking scenarios are explored to validate the use of PenRed and its improved bachytherapy-oriented capabilities for HDR brachytherapy. A new tally allowing the evaluation of collisional kerma for any material using the track length kerma estimator and the possibility to obtain the seed positions, weights and directions processing directly the DICOM file are now implemented in the PenRed distribution. The four non-clinical test cases developed by the Joint AAPM-ESTRO-ABG-ABS WG-DCAB were evaluated by comparing local and global absorbed dose differences with respect to established reference datasets. A prostate and a palliative lung cases, were also studied. For them, absorbed dose ratios, global absorbed dose differences, and cumulative dose-volume histograms were obtained and discussed. Results: The air-kerma strength and the dose rate constant corresponding to the two sources agree with the reference datatests within 0.3% (Sk) and 0.1% (K). With respect to the first three WG-DCAB test cases, more than 99.8% of the voxels present local (global) differences within +/- 1%(+/- 0.1%) of the reference datasets. For test Case 4 reference dataset, more than 94.9%(97.5%) of voxels show an agreement within +/- 1%(+/- 0.1%), better than similar benchmarking calculations in the literature. The track length kerma estimator scorer implemented increases the numerical efficiency of brachytherapy calculations two orders of magnitude, while the specific brachytherapy source allows the user to avoid the use of error-prone intermediate steps to translate the DICOM information into the simulation. In both clinical cases, only minor absorbed dose differences arise in the low-dose isodoses. 99.8% and 100% of the voxels have a global absorbed dose difference ratio within +/- 0.2%for the prostate and lung cases, respectively. The role played by the different segmentation and composition material in the bone structures was discussed, obtaining negligible absorbed dose differ-ences. Dose-volume histograms were in agreement with the reference data.Conclusions: PenRed incorporates new tallies and utilities and has been validated for its use for detailed and precise high-dose-rate brachytherapy simulations.  
  Address [Oliver, S.] Univ Politecn Valencia, Inst Segur Ind, Radiofis & Medioambiental ISIRYM, Camide Vera s n, Valencia 46022, Spain, Email: sanolgi@upvnet.upv.es  
  Corporate Author Thesis  
  Publisher Elsevier Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0939-3889 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001137118400001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5885  
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Author Pujades, M.C.; Granero, D.; Vijande, J.; Ballester, F.; Perez-Calatayud, J.; Papagiannis, P.; Siebert, F.A. doi  openurl
  Title Air-kerma evaluation at the maze entrance of HDR brachytherapy facilities Type Journal Article
  Year 2014 Publication Journal of Radiological Protection Abbreviated Journal J. Radiol. Prot.  
  Volume (up) 34 Issue 4 Pages 741-753  
  Keywords bunker; shielding; NCRP 151; brachytherapy; Monte Carlo  
  Abstract In the absence of procedures for evaluating the design of brachytherapy (BT) facilities for radiation protection purposes, the methodology used for external beam radiotherapy facilities is often adapted. The purpose of this study is to adapt the NCRP 151 methodology for estimating the air-kerma rate at the door in BT facilities. Such methodology was checked against Monte Carlo (MC) techniques using the code Geant4. Five different facility designs were studied for Ir-192 and Co-60 HDR applications to account for several different bunker layouts. For the estimation of the lead thickness needed at the door, the use of transmission data for the real spectra at the door instead of the ones emitted by Ir-192 and Co-60 will reduce the lead thickness by a factor of five for Ir-192 and ten for Co-60. This will significantly lighten the door and hence simplify construction and operating requirements for all bunkers. The adaptation proposed in this study to estimate the air-kerma rate at the door depends on the complexity of the maze: it provides good results for bunkers with a maze (i.e. similar to those used for linacs for which the NCRP 151 methodology was developed) but fails for less conventional designs. For those facilities, a specific Monte Carlo study is in order for reasons of safety and cost-effectiveness.  
  Address [Pujades, M. C.] Natl Ctr Dosimetry CND, Valencia, Spain, Email: mpuclau@gmail.com  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0952-4746 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000345895800005 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2031  
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