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Author Etxebeste, A.; Dauvergne, D.; Fontana, M.; Letang, J.M.; Llosa, G.; Muñoz, E.; Oliver, J.F.; Testa, E.; Sarrut, D.
Title CCMod: a GATE module for Compton camera imaging simulation Type Journal Article
Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 65 Issue 5 Pages 055004 - 17pp
Keywords Monte Carlo; simulation; gamma imaging; Compton camera
Abstract Compton cameras are gamma-ray imaging systems which have been proposed for a wide variety of applications such as medical imaging, nuclear decommissioning or homeland security. In the design and optimization of such a system Monte Carlo simulations play an essential role. In this work, we propose a generic module to perform Monte Carlo simulations and analyses of Compton Camera imaging which is included in the open-source GATE/Geant4 platform. Several digitization stages have been implemented within the module to mimic the performance of the most commonly employed detectors (e.g. monolithic blocks, pixelated scintillator crystals, strip detectors...). Time coincidence sorter and sequence coincidence reconstruction are also available in order to aim at providing modules to facilitate the comparison and reproduction of the data taken with different prototypes. All processing steps may be performed during the simulation (on-the-fly mode) or as a post-process of the output files (offline mode). The predictions of the module have been compared with experimental data in terms of energy spectra, angular resolution, efficiency and back-projection image reconstruction. Consistent results within a 3-sigma interval were obtained for the energy spectra except for low energies where small differences arise. The angular resolution measure for incident photons of 1275 keV was also in good agreement between both data sets with a value close to 13 degrees. Moreover, with the aim of demonstrating the versatility of such a tool the performance of two different Compton camera designs was evaluated and compared.
Address [Etxebeste, A.; Letang, J. M.; Sarrut, D.] Univ Lyon 1, Univ Lyon, CREATIS, CNRS UMR5220,Inserm U1044,INSA Lyon, Lyon, France, Email: ane.etxebeste@creatis.insa-lyon.fr
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000519034800001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4321
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Author Etxebeste, A.; Barrio, J.; Bernabeu, J.; Lacasta, C.; Llosa, G.; Muñoz, E.; Ros, A.; Oliver, J.F.
Title Study of sensitivity and resolution for full ring PET prototypes based on continuous crystals and analytical modeling of the light distribution Type Journal Article
Year 2019 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 64 Issue 3 Pages 035015 - 17pp
Keywords continuous crystals; NEMA NU 4-2008; positron emission tomography (PET); Monte Carlo simulations; image reconstruction; depth of interaction
Abstract Sensitivity and spatial resolution are the main parameters to maximize in the performance of a PET scanner. For this purpose, detectors consisting of a combination of continuous crystals optically coupled to segmented photodetectors have been employed. With the use of continuous crystals the sensitivity is increased with respect to the pixelated crystals. In addition, spatial resolution is no longer limited to the crystal size. The main drawback is the difficulty in determining the interaction position. In this work, we present the characterization of the performance of a full ring based on cuboid continuous crystals coupled to SiPMs. To this end, we have employed the simulations developed in a previous work for our experimental detector head. Sensitivity could be further enhanced by using tapered crystals. This enhancement is obtained by increasing the solid angle coverage, reducing the wedge-shaped gaps between contiguous detectors. The performance of the scanners based on both crystal geometries was characterized following NEMA NU 4-2008 standardized protocol in order to compare them. An average sensitivity gain over the entire axial field of view of 13.63% has been obtained with tapered geometry while similar performance of the spatial resolution has been proven with both scanners. The activity at which NECR and true peak occur is smaller and the peak value is greater for tapered crystals than for cuboid crystals. Moreover, a higher degree of homogeneity was obtained in the sensitivity map due to the tighter packing of the crystals, which reduces the gaps and results in a better recovery of homogeneous regions than for the cuboid configuration. Some of the results obtained, such as spatial resolution, depend on the interaction position estimation and may vary if other method is employed.
Address [Etxebeste, Ane; Barrio, John; Bernabeu, Jose; Lacasta, Carlos; Llosa, Gabriela; Munoz, Enrique; Ros, Ana; Oliver, Josef F.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: ane.etxebeste@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000457182500004 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3897
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Author Muñoz, E.; Barrio, J.; Bernabeu, J.; Etxebeste, A.; Lacasta, C.; Llosa, G.; Ros, A.; Roser, J.; Oliver, J.F.
Title Study and comparison of different sensitivity models for a two-plane Compton camera Type Journal Article
Year 2018 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 63 Issue 13 Pages 135004 - 19pp
Keywords Compton camera imaging; MLEM; Monte Carlo simulations; image quality
Abstract Given the strong variations in the sensitivity of Compton cameras for the detection of events originating from different points in the field of view (FoV), sensitivity correction is often necessary in Compton image reconstruction. Several approaches for the calculation of the sensitivity matrix have been proposed in the literature. While most of these models are easily implemented and can be useful in many cases, they usually assume high angular coverage over the scattered photon, which is not the case for our prototype. In this work, we have derived an analytical model that allows us to calculate a detailed sensitivity matrix, which has been compared to other sensitivity models in the literature. Specifically, the proposed model describes the probability of measuring a useful event in a two-plane Compton camera, including the most relevant physical processes involved. The model has been used to obtain an expression for the system and sensitivity matrices for iterative image reconstruction. These matrices have been validated taking Monte Carlo simulations as a reference. In order to study the impact of the sensitivity, images reconstructed with our sensitivity model and with other models have been compared. Images have been reconstructed from several simulated sources, including point-like sources and extended distributions of activity, and also from experimental data measured with Na-22 sources. Results show that our sensitivity model is the best suited for our prototype. Although other models in the literature perform successfully in many scenarios, they are not applicable in all the geometrical configurations of interest for our system. In general, our model allows to effectively recover the intensity of point-like sources at different positions in the FoV and to reconstruct regions of homogeneous activity with minimal variance. Moreover, it can be employed for all Compton camera configurations, including those with low angular coverage over the scatterer.
Address [Munoz, Enrique; Barrio, John; Bernabeu, Jose; Etxebeste, Ane; Lacasta, Carlos; Llosa, Gabriela; Ros, Ana; Roser, Jorge; Oliver, Josep F.] Univ Valencia, CSIC, Inst Fis Corpuscular, IFIC, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000436390800004 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 3639
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Author Martin-Luna, P.; Esperante, D.; Prieto, A.F.; Fuster-Martinez, N.; Rivas, I.G.; Gimeno, B.; Ginestar, D.; Gonzalez-Iglesias, D.; Hueso, J.L.; Llosa, G.; Martinez-Reviriego, P.; Meneses-Felipe, A.; Riera, J.; Regueiro, P.V.; Hueso-Gonzalez, F.
Title Simulation of electron transport and secondary emission in a photomultiplier tube and validation Type Journal Article
Year 2024 Publication Sensors and Actuators A-Physical Abbreviated Journal Sens. Actuator A-Phys.
Volume 365 Issue Pages 114859 - 10pp
Keywords Photomultiplier tube; Photodetector; Proton therapy; Monte Carlo simulation; Measurement
Abstract The electron amplification and transport within a photomultiplier tube (PMT) has been investigated by developing an in-house Monte Carlo simulation code. The secondary electron emission in the dynodes is implemented via an effective electron model and the Modified Vaughan's model, whereas the transport is computed with the Boris leapfrog algorithm. The PMT gain, rise time and transit time have been studied as a function of supply voltage and external magnetostatic field. A good agreement with experimental measurements using a Hamamatsu R13408-100 PMT was obtained. The simulations have been conducted following different treatments of the underlying geometry: three-dimensional, two-dimensional and intermediate (2.5D). The validity of these approaches is compared. The developed framework will help in understanding the behavior of PMTs under highly intense and irregular illumination or varying external magnetic fields, as in the case of prompt gamma-ray measurements during pencil-beam proton therapy; and aid in optimizing the design of voltage dividers with behavioral circuit models.
Address [Martin-Luna, Pablo; Esperante, Daniel; Fuster-Martinez, Nuria; Gimeno, Benito; Gonzalez-Iglesias, Daniel; Llosa, Gabriela; Martinez-Reviriego, Pablo; Meneses-Felipe, Alba; Hueso-Gonzalez, Fernando] CSIC UV, Inst Fis Corpuscular IFIC, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: pablo.martin@uv.es
Corporate Author Thesis
Publisher Elsevier Science Sa Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0924-4247 ISBN Medium
Area Expedition Conference
Notes WOS:001131902700001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 5876
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Author Jordan, D.; Algora, A.; Tain, J.L.
Title An event generator for simulations of complex beta-decay experiments Type Journal Article
Year 2016 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 828 Issue Pages 52-57
Keywords Monte Carlo event generator; Complex beta-decay experiments simulations
Abstract This article describes a Monte Carlo event generator for the design, optimization and performance characterization of beta decay spectroscopy experimental set-ups. The event generator has been developed within the Geant4 simulation architecture and provides new features and greater flexibility in comparison with the current available decay generator.
Address [Jordan, D.; Algora, A.; Tain, J. L.] Univ Valencia, CSIC, Ctr Mixto, Inst Fis Corpuscular, Valencia, Spain, Email: jordan@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000377399700007 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 2714
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