Abstract: We recall that the chiral unitary approach for the interaction of pseudoscalar mesons with the baryons of the decuplet predicts two states for the Xi(1820) resonance, one with a narrow width and the other one with a large width. We contrast this fact with the recent BESIII measurement of the K- Lambda mass distribution in the psi(3686) decay to K- Lambda Xi(+), which demands a width much larger than the average of the PDG, and show how the consideration of the two Xi(1820) states provides a natural explanation to the experimental data.

Abstract: In the framework of the low -energy effective theory containing, in addition to the Standard -Model fields, heavy neutral leptons (HNLs), we compute the decay rates of neutral and charged kaons into HNLs. We consider both lepton -number -conserving and lepton -number -violating four-fermion operators, taking into account also the contribution of active -heavy neutrino mixing. Assuming that the produced HNLs are longlived, we perform simulations and calculate the sensitivities of future long -lived -particle (LLP) detectors at the high -luminosity LHC as well as the near detector of the Deep Underground Neutrino Experiment (DUNE -ND) to the considered scenario. When applicable, we also recast the existing bounds on the minimal mixing case obtained by NA62, T2K, and PS191. Our findings show that, while the future LHC LLP detectors can probe currently allowed parameter space only in certain benchmark scenarios, DUNE -ND should be sensitive to parameter space beyond the current bounds in almost all the benchmark scenarios, and, for some of the effective operators considered, it can even probe new -physics scales in excess of 3000 TeV.

Abstract: Metalenses are composed of nanostructures for focusing light and have been widely explored in many exciting applications. However, their expanding dimensions pose simulation challenges. We propose a method to simulate metalenses in a timely manner using vectorial wave and ray tracing models. We sample the metalens's radial phase gradient and locally approximate the phase profile by a linear phase response. Each sampling point is modeled as a binary blazed grating, employing the chosen nanostructure, to build a transfer function set. The metalens transmission or reflection is then obtained by applying the corresponding transfer function to the incoming field on the regions surrounding each sampling point. Fourier optics is used to calculate the scattered fields under arbitrary illumination for the vectorial wave method, and a Monte Carlo algorithm is used in the ray tracing formalism. We validated our method against finite -difference time domain simulations at 632 nm, and we were able to simulate metalenses larger than 3000 wavelengths in diameter on a personal computer.

Abstract: The MoEDAL's Apparatus for Penetrating Particles (MAPP) Experiment is designed to expand the search for new physics at the LHC, significantly extending the physics program of the baseline MoEDAL Experiment. The Phase-1 MAPP detector (MAPP-1) is currently undergoing installation at the LHC's UA83 gallery adjacent to the LHCb/MoEDAL region at Interaction Point 8 and will begin data-taking in early 2024. The focus of the MAPP experiment is on the quest for new feebly interacting particles – avatars of new physics with extremely small Standard Model couplings, such as minicharged particles (mCPs). In this study, we present the results of a comprehensive analysis of MAPP-1's sensitivity to mCPs arising in the canonical model involving the kinetic mixing of a massless dark U(1) gauge field with the Standard Model hypercharge gauge field. We focus on several dominant production mechanisms of mCPs at the LHC across the mass-mixing parameter space of interest to MAPP: Drell-Yan pair production, direct decays of heavy quarkonia and light vector mesons, and single Dalitz decays of pseudoscalar mesons. The 95% confidence level background-free sensitivity of MAPP-1 for mCPs produced at the LHC's Run 3 and the HL-LHC through these mechanisms, along with projected constraints on the minicharged strongly interacting dark matter window, are reported. Our results indicate that MAPP-1 exhibits sensitivity to sizable regions of unconstrained parameter space and can probe effective charges as low as 8 x 10 -4 e and 6 x 10 -4 e for Run 3 and the HL-LHC, respectively.

Abstract: In small clinical studies, the application of transcranial photobiomodulation (PBM), which typically delivers low-intensity near-infrared (NIR) to treat the brain, has led to some remarkable results in the treatment of dementia and several neurodegenerative diseases. However, despite the extensive literature detailing the mechanisms of action underlying PBM outcomes, the specific mechanisms affecting neurodegenerative diseases are not entirely clear. While large clinical trials are warranted to validate these findings, evidence of the mechanisms can explain and thus provide credible support for PBM as a potential treatment for these diseases. Tubulin and its polymerized state of microtubules have been known to play important roles in the pathology of Alzheimer's and other neurodegenerative diseases. Thus, we investigated the effects of PBM on these cellular structures in the quest for insights into the underlying therapeutic mechanisms. In this study, we employed a Raman spectroscopic analysis of the amide I band of polymerized samples of tubulin exposed to pulsed low-intensity NIR radiation (810 nm, 10 Hz, 22.5 J/cm2 dose). Peaks in the Raman fingerprint region (300-1900 cm-1)-in particular, in the amide I band (1600-1700 cm-1)-were used to quantify the percentage of protein secondary structures. Under this band, hidden signals of C=O stretching, belonging to different structures, are superimposed, producing a complex signal as a result. An accurate decomposition of the amide I band is therefore required for the reliable analysis of the conformation of proteins, which we achieved through a straightforward method employing a Voigt profile. This approach was validated through secondary structure analyses of unexposed control samples, for which comparisons with other values available in the literature could be conducted. Subsequently, using this validated method, we present novel findings of statistically significant alterations in the secondary structures of polymerized NIR-exposed tubulin, characterized by a notable decrease in alpha-helix content and a concurrent increase in beta-sheets compared to the control samples. This PBM-induced alpha-helix to beta-sheet transition connects to reduced microtubule stability and the introduction of dynamism to allow for the remodeling and, consequently, refreshing of microtubule structures. This newly discovered mechanism could have implications for reducing the risks associated with brain aging, including neurodegenerative diseases like Alzheimer's disease, through the introduction of an intervention following this transition.