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Doncel, M., Cederwall, B., Gadea, A., Gerl, J., Kojouharov, I., Martin, S., et al. (2017). Performance and imaging capabilities of the DEGAS high-resolution gamma-ray detector array for the DESPEC experiment at FAIR. Nucl. Instrum. Methods Phys. Res. A, 873, 36–38.
Abstract: Monte Carlo simulations of one of the possible configurations of the imaging phase for the DEGAS spectrometer situated at the DESPEC/NUSTAR experiment have been performed. The geometry consists of the coupling of the high-resolution gamma spectroscopy array, AGATA, with a high-resolution segmented planar detector utilized as an implantation detector in a compact configuration. The sensitivity and performance of the array in terms of efficiency and imaging capability is deduced.
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Clinthorne, N., Brzezinski, K., Chesi, E., Cochran, E., Grkovski, M., Grosicar, B., et al. (2013). Silicon as an unconventional detector in positron emission tomography. Nucl. Instrum. Methods Phys. Res. A, 699, 216–220.
Abstract: Positron emission tomography (PET) is a widely used technique in medical imaging and in studying small animal models of human disease. In the conventional approach, the 511 keV annihilation photons emitted from a patient or small animal are detected by a ring of scintillators such as LYSO read out by arrays of photodetectors. Although this has been successful in achieving similar to 5 mm FWHM spatial resolution in human studies and similar to 1 mm resolution in dedicated small animal instruments, there is interest in significantly improving these figures. Silicon, although its stopping power is modest for 511 keV photons, offers a number of potential advantages over more conventional approaches including the potential for high intrinsic spatial resolution in 3D. To evaluate silicon in a variety of PET “magnifying glass” configurations, an instrument was constructed that consists of an outer partial-ring of PET scintillation detectors into which various arrangements of silicon detectors are inserted to emulate dual-ring or imaging probe geometries. Measurements using the test instrument demonstrated the capability of clearly resolving point sources of Na-22 having a 1.5 mm center-to-center spacing as well as the 1.2 mm rods of a F-18-filled resolution phantom. Although many challenges remain, silicon has potential to become the PET detector of choice when spatial resolution is the primary consideration. (C) 2012 Elsevier B.V. All rights reserved.
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Domingo-Pardo, C. (2012). A new technique for 3D gamma-ray imaging: Conceptual study of a 3D camera. Nucl. Instrum. Methods Phys. Res. A, 675, 123–132.
Abstract: A novel technique for 3D gamma-ray imaging is presented. This method combines the positron annihilation Compton scattering imaging technique with a supplementary position sensitive detector, which registers gamma-rays scattered in the object at angles of about 90 degrees. The 3D coordinates of the scattering location can be determined rather accurately by applying the Compton principle. This method requires access to the object from two orthogonal sides and allows one to achieve a position resolution of few mm in all three space coordinates. A feasibility study for a 3D camera is presented based on Monte Carlo calculations.
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Llosa, G., Barrio, J., Cabello, J., Crespo, A., Lacasta, C., Rafecas, M., et al. (2012). Detector characterization and first coincidence tests of a Compton telescope based on LaBr3 crystals and SiPMs. Nucl. Instrum. Methods Phys. Res. A, 695, 105–108.
Abstract: A Compton telescope for dose monitoring in hadron therapy consisting of several layers of continuous LaBr3 crystals coupled to silicon photomultiplier (SiPM) arrays is under development within the ENVISION project. In order to test the possibility of employing such detectors for the telescope, a detector head consisting of a continuous 16 mm x 18 mm x 5 mm LaBr3 crystal coupled to a SiPM array has been assembled and characterized, employing the SPIROC1 ASIC as readout electronics. The best energy resolution obtained at 511 key is 6.5% FWHM and the timing resolution is 3.1 ns FWHM. A position determination method for continuous crystals is being tested, with promising results. In addition, the detector has been operated in time coincidence with a second detector layer, to determine the coincidence capabilities of the system. The first tests are satisfactory, and encourage the development of larger detectors that will compose the telescope prototype.
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Llosa, G., Barrio, J., Lacasta, C., Callier, S., Raux, L., & de La Taille, C. (2011). First tests in the application of silicon photomultiplier arrays to dose monitoring in hadron therapy. Nucl. Instrum. Methods Phys. Res. A, 648, S96–S99.
Abstract: A detector head composed of a continuous LaBr3 crystal coupled to a silicon photomultiplier array has been mounted and tested, for its use in a Compton telescope for dose monitoring in hadron therapy. The LaBr3 crystal has 16 mm x 18 mm x 5 mm size, and it is surrounded with reflecting material in five faces. The SiPM array has 16 (4 x 4) elements of 3 mm x 3 mm size. The SPIROC1 ASIC has been employed as readout electronics. The detector shows a linear behavior up to 1275 keV. The energy resolution obtained at 511 keV is 7% FWHM, and it varies as one over the square root of the energy up to the energies tested. The variations among the detector channels are within 12%. A preliminary measurement of the timing resolution gives 7 ns FWHM. The spatial resolution obtained with the center of gravity method is 1.2 mm FWHM. The tests performed confirm the correct functioning of the detector.
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AGATA Collaboration, Doncel, M., Quintana, B., Gadea, A., Recchia, F., & Farnea, E. (2011). Background rejection capabilities of a Compton imaging telescope setup with a DSSD Ge planar detector and AGATA. Nucl. Instrum. Methods Phys. Res. A, 648, S131–S134.
Abstract: In this work, we show the first Monte Carlo results about the performance of the Ge array which we propose for the DESPEC experiment at FAIR, when the background algorithm developed for AGATA is applied. The main objective of our study is to characterize the capabilities of the gamma-spectroscopy system, made up of AGATA detectors in a semi-spherical distribution covering a 1 pi solid angle and a set of planar Ge detectors in a daisy configuration, to discriminate between gamma sources placed at different locations.
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Carles, M., Lerche, C. W., Sanchez, F., Mora, F., & Benlloch, J. M. (2011). Position correction with depth of interaction information for a small animal PET system. Nucl. Instrum. Methods Phys. Res. A, 648, S176–S180.
Abstract: In this work we study the effects on the spatial resolution when depth of interaction (001) information is included in the parameterization of the line of response (LOR) for a small animal positron emission tomography (PET) system. One of the most important degrading factors for PET is the parallax error introduced in systems that do not provide DOI information of the recorded gamma-rays. Our group has designed a simple and inexpensive method for DOI determination in continuous scintillation crystals. This method is based, on one hand, in the correlation between the scintillation light distribution width in monolithic crystals and the DOI, and, on the other hand, on a small modification of the widely applied charge dividing circuits (CDR). In this work we present a new system calibration that includes the DOI information, and also the development of the correction equations that relates the LOR without and with DOI information. We report the results obtained for different measurements along the transaxial field of view (FOV) and the image quality enhancement achieved specially at the edge of the FOV.
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AGATA Collaboration, Doncel, M., Recchia, F., Quintana, B., Gadea, A., & Farnea, E. (2010). Experimental test of the background rejection, through imaging capability, of a highly segmented AGATA germanium detector. Nucl. Instrum. Methods Phys. Res. A, 622(3), 614–618.
Abstract: The development of highly segmented germanium detectors as well as the algorithms to identify the position of the interaction within the crystal opens the possibility to locate the gamma-ray source using Compton imaging algorithms. While the Compton-suppression shield, coupled to the germanium detector in conventional arrays, works also as an active filter against the gamma rays originated outside the target, the new generation of position sensitive gamma-ray detector arrays has to fully rely on tracking capabilities for this purpose. In specific experimental conditions, as the ones foreseen at radioactive beam facilities, the ability to discriminate background radiation improves the sensitivity of the gamma spectrometer. In this work we present the results of a measurement performed at the Laboratori Nazionali di Legnaro (LNL) aiming the evaluation of the AGATA detector capabilities to discriminate the origin of the gamma rays on an event-by-event basis. It will be shown that, exploiting the Compton scattering formula, it is possible to track back gamma rays coming from different positions, assigning them to specific emitting locations. These imaging capabilities are quantified for a single crystal AGATA detector.
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Rodriguez-Alvarez, M. J., Sanchez, F., Soriano, A., Iborra, A., & Mora, C. (2011). Exploiting symmetries for weight matrix design in CT imaging. Math. Comput. Model., 54(7-8), 1655–1664.
Abstract: In this paper we propose several methods of constructing the system matrix (SM) of a Computed Tomography (CT) scanner with two objectives: (1) to construct SMs in the shortest possible time and store them in an ordinary PC without losing quality, (2) to analyze the possible applications of the proposed method to 3D, taking into account SMs' sizes, computing time and reconstructed image quality. In order to build the SM, we propose two new field of view (FOV) pixellation schemes, based on a polar coordinate system (polar grid) by taking advantage of the polar rotation symmetries of CT devices. Comparisons between the SMs proposed are performed using two phantom and a real CT-simulator images. Global error, contrast, noise and homogeneity of the reconstructed images are discussed.
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