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Author |
Schaffter, T. et al; Albiol, F.; Caballero, L. |
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Title |
Evaluation of Combined Artificial Intelligence and Radiologist Assessment to Interpret Screening Mammograms |
Type |
Journal Article |
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Year |
2020 |
Publication |
JAMA Network Open |
Abbreviated Journal |
JAMA Netw. Open |
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Volume |
3 |
Issue |
3 |
Pages |
e200265 - 15pp |
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Keywords |
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Abstract |
Importance Mammography screening currently relies on subjective human interpretation. Artificial intelligence (AI) advances could be used to increase mammography screening accuracy by reducing missed cancers and false positives. Objective To evaluate whether AI can overcome human mammography interpretation limitations with a rigorous, unbiased evaluation of machine learning algorithms. Design, Setting, and Participants In this diagnostic accuracy study conducted between September 2016 and November 2017, an international, crowdsourced challenge was hosted to foster AI algorithm development focused on interpreting screening mammography. More than 1100 participants comprising 126 teams from 44 countries participated. Analysis began November 18, 2016. Main Outcomes and Measurements Algorithms used images alone (challenge 1) or combined images, previous examinations (if available), and clinical and demographic risk factor data (challenge 2) and output a score that translated to cancer yes/no within 12 months. Algorithm accuracy for breast cancer detection was evaluated using area under the curve and algorithm specificity compared with radiologists' specificity with radiologists' sensitivity set at 85.9% (United States) and 83.9% (Sweden). An ensemble method aggregating top-performing AI algorithms and radiologists' recall assessment was developed and evaluated. Results Overall, 144231 screening mammograms from 85580 US women (952 cancer positive <= 12 months from screening) were used for algorithm training and validation. A second independent validation cohort included 166578 examinations from 68008 Swedish women (780 cancer positive). The top-performing algorithm achieved an area under the curve of 0.858 (United States) and 0.903 (Sweden) and 66.2% (United States) and 81.2% (Sweden) specificity at the radiologists' sensitivity, lower than community-practice radiologists' specificity of 90.5% (United States) and 98.5% (Sweden). Combining top-performing algorithms and US radiologist assessments resulted in a higher area under the curve of 0.942 and achieved a significantly improved specificity (92.0%) at the same sensitivity. Conclusions and Relevance While no single AI algorithm outperformed radiologists, an ensemble of AI algorithms combined with radiologist assessment in a single-reader screening environment improved overall accuracy. This study underscores the potential of using machine learning methods for enhancing mammography screening interpretation. Question How do deep learning algorithms perform compared with radiologists in screening mammography interpretation? Findings In this diagnostic accuracy study using 144231 screening mammograms from 85580 women from the United States and 166578 screening mammograms from 68008 women from Sweden, no single artificial intelligence algorithm outperformed US community radiologist benchmarks; including clinical data and prior mammograms did not improve artificial intelligence performance. However, combining best-performing artificial intelligence algorithms with single-radiologist assessment demonstrated increased specificity. Meaning Integrating artificial intelligence to mammography interpretation in single-radiologist settings could yield significant performance improvements, with the potential to reduce health care system expenditures and address resource scarcity experienced in population-based screening programs. This diagnostic accuracy study evaluates whether artificial intelligence can overcome human mammography interpretation limits with a rigorous, unbiased evaluation of machine learning algorithms. |
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[Schaffter, Thomas; Hoff, Bruce; Yu, Thomas; Neto, Elias Chaibub; Friend, Stephen; Guinney, Justin] Sage Bionetworks, Computat Oncol, Seattle, WA USA, Email: gustavo@us.ibm.com |
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Amer Medical Assoc |
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2574-3805 |
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WOS:000519249800002 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4683 |
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Author |
Vento, V. |
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Title |
Ions, Protons, and Photons as Signatures of Monopoles |
Type |
Journal Article |
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Year |
2018 |
Publication |
Universe |
Abbreviated Journal |
Universe |
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Volume |
4 |
Issue |
11 |
Pages |
117 - 12pp |
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Abstract |
Magnetic monopoles have been a subject of interest since Dirac established the relationship between the existence of monopoles and charge quantization. The Dirac quantization condition bestows the monopole with a huge magnetic charge. The aim of this study was to determine whether this huge magnetic charge allows monopoles to be detected by the scattering of charged ions and protons on matter where they might be bound. We also analyze if this charge favors monopolium (monopole-antimonopole) annihilation into many photons over two photon decays. |
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Address |
[Vento, Vicente] Univ Valencia, CSIC, IFIC, Dept Fis Teor, E-46100 Burjassot, Valencia, Spain, Email: vicente.vento@uv.es |
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Mdpi |
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English |
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2218-1997 |
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Notes |
WOS:000451167700007 |
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no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
3819 |
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Author |
Gersabeck, E.; Pich, A. |
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Title |
Tau and charm decays |
Type |
Journal Article |
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Year |
2020 |
Publication |
Comptes Rendus Physique |
Abbreviated Journal |
C. R. Phys. |
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Volume |
21 |
Issue |
1 |
Pages |
75-92 |
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Keywords |
Tau and charm physics; D-0 mixing; CP violation |
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Abstract |
A summary of recent precise results in tau and charm physics is presented. Topics include leptonic and hadronic tau decays, lepton flavour and lepton number violation, charm mixing and CP violation, leptonic and semileptonic charm decays, rare decays and spectroscopy. |
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Address |
[Gersabeck, Evelina] Univ Manchester, Oxford Rd, Manchester M13 9PL, Lancs, England, Email: evelina.gersabeck@cern.ch; |
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Publisher |
centre Mersenne pour ldition scientifique ouverte |
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English |
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ISSN |
1631-0705 |
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Notes |
WOS:000573985600006 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4550 |
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Author |
ATLAS Collaboration (Aad, G. et al); Aparisi Pozo, J.A.; Bailey, A.J.; Cabrera Urban, S.; Castillo, F.L.; Castillo Gimenez, V.; Costa, M.J.; Escobar, C.; Estrada Pastor, O.; Ferrer, A.; Fiorini, L.; Fullana Torregrosa, E.; Fuster, J.; Garcia, C.; Garcia Navarro, J.E.; Gonzalez de la Hoz, S.; Gonzalvo Rodriguez, G.R.; Guerrero Rojas, J.G.R.; Higon-Rodriguez, E.; Lacasta, C.; Lozano Bahilo, J.J.; Madaffari, D.; Mamuzic, J.; Marti-Garcia, S.; Martinez Agullo, P.; Mitsou, V.A.; Moreno Llacer, M.; Poveda, J.; Rodriguez Bosca, S.; Ruiz-Martinez, A.; Salt, J.; Santra, A.; Sayago Galvan, I.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valero, A.; Valls Ferrer, J.A.; Vos, M. |
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Title |
Search for quantum black hole production in lepton plus jet final states using proton-proton collisions at √s=13 TeV with the ATLAS detector |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
109 |
Issue |
3 |
Pages |
032010 - 28pp |
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Abstract |
A search for quantum black holes in electron + jet and muon + jet invariant mass spectra is performed with 140 fb(-1) of data collected by the ATLAS detector in proton-proton collisions at root s = 13 TeV at the Large Hadron Collider. The observed invariant mass spectrum of lepton + jet pairs is consistent with Standard Model expectations. Upper limits are set at 95% confidence level on the production cross section times branching fractions for quantum black holes decaying into a lepton and a quark in a search region with invariant mass above 2.0 TeV. The resulting quantum black hole lower mass threshold limit is 9.2 TeV in the Arkani-Hamed-Dimopoulos-Dvali model, and 6.8 TeV in the Randall-Sundrum model. |
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Address |
[Jackson, P.; Kong, A. X. Y.; Oliver, J. L.; Petridis, A.; Ruggeri, T. A.; Sharma, A. S.; White, M. J.] Univ Adelaide, Dept Phys, Adelaide, SA, Australia |
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Publisher |
Amer Physical Soc |
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English |
Summary Language |
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Original Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2470-0010 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001183228500014 |
Approved |
no |
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Is ISI |
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International Collaboration |
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Call Number |
IFIC @ pastor @ |
Serial |
5987 |
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Author |
Cervantes, D.; Fioresi, R.; Lledo, M.A.; Nadal, F.A. |
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Title |
Quantum Twistors |
Type |
Journal Article |
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Year |
2016 |
Publication |
P-Adic Numbers Ultrametric Analysis and Applications |
Abbreviated Journal |
P-Adic Num. |
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Volume |
8 |
Issue |
1 |
Pages |
2-30 |
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Keywords |
star products; non commutative spacetime; quantum groups |
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Abstract |
We compute explicitly a star product on the Minkowski space whose Poisson bracket is quadratic. This star product corresponds to a deformation of the conformal spacetime, whose big cell is the Minkowski spacetime. The description of Minkowski space is made in the twistor formalism and the quantization follows by substituting the classical conformal group by a quantum group. |
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Address |
[Cervantes, D.] IPN, CINVESTAV, Comp Sci Dept, Mexico City, DF, Mexico, Email: dalia@computacion.cs.cinvestav.mx; |
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Publisher |
Maik Nauka-Interperiodica |
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English |
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Original Title |
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Series Volume |
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Edition |
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ISSN |
2070-0466 |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000410319300001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3295 |
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Author |
BABAR Collaboration (Lees, J.P. et al); Martinez-Vidal, F.; Oyanguren, A.; Villanueva-Perez, P. |
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Title |
Evidence for CP violation in B+ -> K*(892)(+)pi(0) from a Dalitz plot analysis of B+ -> K-S(0) pi(+)pi(0) decays |
Type |
Journal Article |
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Year |
2017 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
96 |
Issue |
7 |
Pages |
072001 - 21pp |
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Keywords |
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Abstract |
We report a Dalitz plot analysis of charmless hadronic decays of charged B mesons to the final state K-S(0)pi(1) pi(0) using the full BABAR data set of 470.9 +/- 2.8 million B (B) over bar events collected at the gamma (4S) resonance. We measure the overall branching fraction and CP asymmetry to be B(B+ -> K-0 pi(+)pi(0)) = (31.8 +/- 1.8 +/- 2.1(-0.0)(+6.0)) x 10(-6) and A(CP)(B+ -> K-0 pi(+)pi(0)) = 0.07 +/- 0.05 +/- 0.03(-0.03)(+0.02), where the uncertainties are statistical, systematic, and due to the signal model, respectively. This is the first measurement of the branching fraction for B+ -> K-0 pi(+)pi(0). We find first evidence of a CP asymmetry in B+ -> K*(892)(+) pi(0) decays: A(CP)(B+ -> K*(892)(+)pi(0)) = -0.52 +/- 0.14 +/- 0.04(-0.02)(+0.04). The significance of this asymmetry, including systematic and model uncertainties, is 3.4 standard deviations. We also measure the branching fractions and CP asymmetries for three other intermediate decay modes. |
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Address |
[Lees, J. P.; Poireau, V.; Tisserand, V.] Univ Savoie, CNRS, IN2P3, Lab Annecy le Vieux Phys Particules LAPP, F-74941 Annecy Le Vieux, France |
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Publisher |
Amer Physical Soc |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2470-0010 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000412031400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3314 |
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Author |
Flores-Tlalpa, A.; Lopez Castro, G.; Roig, P. |
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Title |
Five-body leptonic decays of muon and tau lepton |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
04 |
Issue |
4 |
Pages |
185 - 21pp |
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Keywords |
CP violation; Discrete Symmetries; Effective field theories; Precision QED |
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Abstract |
We study the five-body decays u(-) -> e(-)e(+)e(-)nu u (nu) over bar (e) and tau(-) -> l(-)l'+l'-nu(tau)(nu) over bar (l) for l, l' = e, u within the Standard Model (SM) and in a general effective field theory description of the weak interactions at low energies. We compute the branching ratios and compare our results with two previous – mutually discrepan – SM calculations. By assuming a general structure for the weak currents we derive the expressions for the energy and angular distributions of the three charged leptons when the decaying lepton is polarized, which will be useful in precise tests of the weak charged current at Belle II. In these decays, leptonic T-odd correlations in triple products of spin and momenta – which may signal time reversal violation in the leptonic sector – are suppressed by the tiny neutrino masses. Therefore, a measurement of such T-violating observables would be associated to neutrinoless lepton flavor violating (LFV) decays, where this effect is not extremely suppressed. We also study the backgrounds that the SM five-lepton lepton decays constitute to searches of LFV L- -> ? l(-)l'+l'(-) decays. Searches at high values of the invariant mass of the l'(+)l'(-) pair look the most convenient way to overcome the background. |
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Address |
[Flores-Tlalpa, A.] Univ Nacl Autonoma Mexico, Inst Fis, Apartado Postal 20-364, Mexico City 01000, DF, Mexico, Email: alain@fisica.unam.mx; |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1029-8479 |
ISBN |
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Conference |
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Notes |
WOS:000411265800003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3501 |
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Author |
Rocha-Moran, P.; Vicente, A. |
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Title |
Lepton Flavor Violation in the singlet-triplet scotogenic model |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
07 |
Issue |
7 |
Pages |
078 - 25pp |
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Keywords |
Neutrino Physics; Beyond Standard Model |
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Abstract |
We investigate lepton flavor violation (LFV) in the the singlet-triplet scotogenic model in which neutrinos acquire non-zero masses at the 1-loop level. In contrast to the most popular variant of this setup, the singlet scotogenic model, this version includes a triplet fermion as well as a triplet scalar, leading to a scenario with a richer dark matter phenomenology. Taking into account results from neutrino oscillation experiments, we explore some aspects of the LFV phenomenology of the model. In particular, we study the relative weight of the dipole operators with respect to other contributions to the LFV amplitudes and determine the most constraining observables. We show that in large portions of the parameter space, the most promising experimental perspectives are found for LFV 3-body decays and for coherent mu-e conversion in nuclei. |
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Address |
[Rocha-Moran, Paulina; Vicente, Avelino] Univ Valencia, CSIC, Inst Fis Corpuscular, Apdo 22085, E-46071 Valencia, Spain, Email: procha@th.physik.uni-bonn.de; |
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Publisher |
Springer |
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English |
Summary Language |
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ISSN |
1029-8479 |
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Conference |
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Notes |
WOS:000411315600006 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3500 |
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Author |
Gariazzo, S.; Mena, O.; Ramirez, H.; Boubekeur, L. |
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Title |
Primordial power spectrum features in phenomenological descriptions of inflation |
Type |
Journal Article |
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Year |
2017 |
Publication |
Physics of the Dark Universe |
Abbreviated Journal |
Phys. Dark Universe |
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Volume |
17 |
Issue |
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Pages |
38-45 |
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Keywords |
Inflation; Primordial power spectrum; Sound speed |
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Abstract |
We extend an alternative, phenomenological approach to inflation by means of an equation of state and a sound speed, both of them functions of the number of e-folds and four phenomenological parameters. This approach captures a number of possible inflationary models, including those with non-canonical kinetic terms or scale-dependent non-gaussianities. We perform Markov Chain Monte Carlo analyses using the latest cosmological publicly available measurements, which include Cosmic Microwave Background (CMB) data from the Planck satellite. Within this parameterization, we discard scale invariance with a significance of about 10 sigma, and the running of the spectral index is constrained as alpha(s) = -0.60(-0.10)(+0.08) x 10(-3) (68% CL errors). The limit on the tensor-to-scalar ratio is r < 0.005 at 95% CL from CMB data alone. We find no significant evidence for this alternative parameterization with present cosmological observations. The maximum amplitude of the equilateral non-gaussianity that we obtain, vertical bar f(NL)(equil)vertical bar < 1, is much smaller than the current Planck mission errors, strengthening the case for future high-redshift, all-sky surveys, which could reach the required accuracy on equilateral non-gaussianities. |
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Address |
[Gariazzo, Stefano] Univ Turin, Dept Phys, Via P Giuria 1, I-10125 Turin, Italy, Email: omena@ific.uv.es |
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Publisher |
Elsevier Science Bv |
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English |
Summary Language |
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Series Editor |
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ISSN |
2212-6864 |
ISBN |
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Area |
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Notes |
WOS:000411869100006 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3319 |
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Author |
Bejarano, C.; Lobo, F.S.N.; Olmo, G.J.; Rubiera-Garcia, D. |
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Title |
Palatini wormholes and energy conditions from the prism of general relativity |
Type |
Journal Article |
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Year |
2017 |
Publication |
European Physical Journal C |
Abbreviated Journal |
Eur. Phys. J. C |
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Volume |
77 |
Issue |
11 |
Pages |
776 - 13pp |
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Keywords |
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Abstract |
Wormholes are hypothetical shortcuts in space-time that in general relativity unavoidably violate all of the pointwise energy conditions. In this paper, we consider several wormhole spacetimes that, as opposed to the standard designer procedure frequently employed in the literature, arise directly from gravitational actions including additional terms resulting from contractions of the Ricci tensor with the metric, and which are formulated assuming independence between metric and connection (Palatini approach). We reinterpret such wormhole solutions under the prism of General Relativity and study the matter sources that thread them. We discuss the size of violation of the energy conditions in different cases and how this is related to the same spacetimes when viewed from the modified gravity side. |
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Address |
[Bejarano, Cecilia] CONICET UBA, IAFE, Casilla Correo 67,Sucursal 28, RA-1428 Buenos Aires, DF, Argentina, Email: cbejarano@iafe.uba.ar; |
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Publisher |
Springer |
Place of Publication |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6044 |
ISBN |
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Conference |
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Notes |
WOS:000415697400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3372 |
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