Garcia, A. R., Mendoza, E., Cano-Ott, D., Nolte, R., Martinez, T., Algora, A., et al. (2017). New physics model in GEANT4 for the simulation of neutron interactions with organic scintillation detectors. Nucl. Instrum. Methods Phys. Res. A, 868, 73–81.
Abstract: The accurate determination of the response function of organic scintillation neutron detectors complements their experimental characterization. Monte Carlo simulations with GEANT4 can reduce the effort and cost implied, especially for complex detection systems for which the characterization is more challenging. Previous studies have reported on the inaccuracy of GEANT4 in the calculation of the neutron response of organic scintillation detectors above 6 MeV, due to an incomplete description of the neutron-induced alpha production reactions on carbon. We have improved GEANT4 in this direction by incorporating models and data from NRESP, an excellent Monte Carlo simulation tool developed at the Physikalisch-Technische Bundesanstalt (PTB), Germany, for the specific purpose of calculating the neutron response function of organic scintillation detectors. The results have been verified against simulations with NRESP and validated against Time-Of-Flight measurements with an NE213 detector at PTB. This work has potential applications beyond organic scintillation detectors, to other types of detectors where reactions induced by fast neutrons on carbon require an accurate description.
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Doncel, M., Cederwall, B., Gadea, A., Gerl, J., Kojouharov, I., Martin, S., et al. (2017). Performance and imaging capabilities of the DEGAS high-resolution gamma-ray detector array for the DESPEC experiment at FAIR. Nucl. Instrum. Methods Phys. Res. A, 873, 36–38.
Abstract: Monte Carlo simulations of one of the possible configurations of the imaging phase for the DEGAS spectrometer situated at the DESPEC/NUSTAR experiment have been performed. The geometry consists of the coupling of the high-resolution gamma spectroscopy array, AGATA, with a high-resolution segmented planar detector utilized as an implantation detector in a compact configuration. The sensitivity and performance of the array in terms of efficiency and imaging capability is deduced.
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AGATA Collaboration(Clement, E. et al), Domingo-Pardo, C., Gadea, A., Perez-Vidal, R. M., & Civera, J. V. (2017). Conceptual design of the AGATA 1 pi array at GANIL. Nucl. Instrum. Methods Phys. Res. A, 855, 1–12.
Abstract: The Advanced GAmma Tracking Array (AGATA) has been installed at the GANIL facility, Caen-France. This setup exploits the stable and radioactive heavy-ions beams delivered by the cyclotron accelerator complex of GANIL. Additionally, it benefits from a large palette of ancillary detectors and spectrometers to address in-beam gamma-ray spectroscopy of exotic nuclei. The set-up has been designed to couple AGATA with a magnetic spectrometer, charged-particle and neutron detectors, scintillators for the detection of high-energy gamma rays and other devices such as a plunger to measure nuclear lifetimes. In this paper, the design and the mechanical characteristics of the set-up are described. Based on simulations, expected performances of the AGATA l pi array are presented.
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Becker, R., Buck, A., Casella, C., Dissertori, G., Fischer, J., Howard, A., et al. (2017). The SAFIR experiment: Concept, status and perspectives. Nucl. Instrum. Methods Phys. Res. A, 845, 648–651.
Abstract: The SAFIR development represents a novel Positron Emission Tomography (PET) detector, conceived for preclinical fast acquisitions inside the bore of a Magnetic Resonance Imaging (MRI) scanner. The goal is hybrid and simultaneous PET/MRI dynamic studies at unprecedented temporal resolutions of a few seconds. The detector relies on matrices of scintillating LSO-based crystals coupled one-to-one with SiPM arrays and readout by fast ASIC5 with excellent timing resolution and high rate capabilities. The paper describes the detector concept and the initial results in terms of simulations and characterisation measurements.
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Azevedo, C. D. R., Baeza, A., Chauveau, E., Corbacho, J. A., Diaz, J., Domange, J., et al. (2023). Design, setup and routine operation of a water treatment system for the monitoring of low activities of tritium in water. Nucl. Eng. Technol., 55(7), 2349–2355.
Abstract: In the TRITIUM project, an on-site monitoring system is being developed to measure tritium (3H) levels in water near nuclear power plants. The quite low-energy betas emitted by 3H have a very short average path in water (5 mm as shown by simulations for 18 keV electrons). This path would be further reduced by impurities present in the water, resulting in a significant reduction of the detection efficiency. Therefore, one of the essential requirements of the project is the elimination of these impurities through a filtration process and the removal of salts in solution. This paper describes a water treatment system developed for the project that meets the following requirements: the water produced should be of nearpure water quality according to ISO 3696 grade 3 standard (conductivity < 10 mS/cm); the system should operate autonomously and be remotely monitored.
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Liang, J., Singh, B., McCutchan, E. A., Dillmann, I., Birch, M., Sonzogni, A. A., et al. (2020). Compilation and Evaluation of Beta-Delayed Neutron Emission Probabilities and Half-Lives for Z > 28 Precursors. Nucl. Data Sheets, 168, 1–116.
Abstract: We present a compilation and evaluation of experimental beta-delayed neutron emission probabilities (P-n) and half-lives (T-1/2) for known or potential beta-delayed neutron precursors with atomic number Z > 28 (Cu-73 – Fr-233). This article includes the recommended values of both of these quantities, together with a compilation of experimental measurements when available. Some notable cases, as well as proposed standards for beta-delayed neutron measurements are also discussed. Evaluated data has also been compared to systematics using three different approaches. The literature cut-off date for this work is August 15, 2020.
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Albiol, F., Corbi, A., & Albiol, A. (2017). 3D measurements in conventional X-ray imaging with RGB-D sensors. Med. Eng. Phys., 42, 73–79.
Abstract: A method for deriving 3D internal information in conventional X-ray settings is presented. It is based on the combination of a pair of radiographs from a patient and it avoids the use of X-ray-opaque fiducials and external reference structures. To achieve this goal, we augment an ordinary X-ray device with a consumer RGB-D camera. The patient' s rotation around the craniocaudal axis is tracked relative to this camera thanks to the depth information provided and the application of a modern surface-mapping algorithm. The measured spatial information is then translated to the reference frame of the X-ray imaging system. By using the intrinsic parameters of the diagnostic equipment, epipolar geometry, and X-ray images of the patient at different angles, 3D internal positions can be obtained. Both the RGB-D and Xray instruments are first geometrically calibrated to find their joint spatial transformation. The proposed method is applied to three rotating phantoms. The first two consist of an anthropomorphic head and a torso, which are filled with spherical lead bearings at precise locations. The third one is made of simple foam and has metal needles of several known lengths embedded in it. The results show that it is possible to resolve anatomical positions and lengths with a millimetric level of precision. With the proposed approach, internal 3D reconstructed coordinates and distances can be provided to the physician. It also contributes to reducing the invasiveness of ordinary X-ray environments and can replace other types of clinical explorations that are mainly aimed at measuring or geometrically relating elements that are present inside the patient's body.
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Fernandez, A., Hufschmidt, D., Colaux, J. L., Valiente-Dobon, J. J., Godinho, V., Jimenez de Haro, M. C., et al. (2020). Low gas consumption fabrication of He-3 solid targets for nuclear reactions. Mater. Des., 186, 108337–10pp.
Abstract: Nanoporous solids that stabilize trapped gas nanobubbles open new possibilities to fabricate solid targets for nuclear reactions. A methodology is described based on the magnetron sputtering (MS) technique operated under quasistatic flux conditions to produce such nanocomposites films with He-3 contents of up to 16 at.% in an amorphous-silicon matrix. In addition to the characteristic low pressure (3-6 Pa) needed for the gas discharge, the method ensures almost complete reduction of the process gas flow during film fabrication. The method could produce similar materials to those obtained under classical dynamic flux conditions for MS. The drastic reduction (>99.5%) of the gas consumption is fundamental for the fabrication of targets with scarce and expensive gases. Si:He-3 and W:He-3 targets are presented together with their microstructural (scanning and transmission electron microscopy, SEM and TEM respectively) and compositional (Ion Beam Analysis, IBA) characterization. The He-3 content achieved was over 1 x 10(18) at/cm(2) for film thicknesses between 1.5 and 3 μm for both Si and W matrices. First experiments to probe the stability of the targets for nuclear reaction studies in inverse kinematics configurations are presented.
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Carrasco-Ribelles, L. A., Pardo-Mas, J. R., Tortajada, S., Saez, C., Valdivieso, B., & Garcia-Gomez, J. M. (2021). Predicting morbidity by local similarities in multi-scale patient trajectories. J. Biomed. Inform., 120, 103837–9pp.
Abstract: Patient Trajectories (PTs) are a method of representing the temporal evolution of patients. They can include information from different sources and be used in socio-medical or clinical domains. PTs have generally been used to generate and study the most common trajectories in, for instance, the development of a disease. On the other hand, healthcare predictive models generally rely on static snapshots of patient information. Only a few works about prediction in healthcare have been found that use PTs, and therefore benefit from their temporal dimension. All of them, however, have used PTs created from single-source information. Therefore, the use of longitudinal multi-scale data to build PTs and use them to obtain predictions about health conditions is yet to be explored. Our hypothesis is that local similarities on small chunks of PTs can identify similar patients concerning their future morbidities. The objectives of this work are (1) to develop a methodology to identify local similarities between PTs before the occurrence of morbidities to predict these on new query individuals; and (2) to validate this methodology on risk prediction of cardiovascular diseases (CVD) occurrence in patients with diabetes. We have proposed a novel formal definition of PTs based on sequences of longitudinal multi-scale data. Moreover, a dynamic programming methodology to identify local alignments on PTs for predicting future morbidities is proposed. Both the proposed methodology for PT definition and the alignment algorithm are generic to be applied on any clinical domain. We validated this solution for predicting CVD in patients with diabetes and we achieved a precision of 0.33, a recall of 0.72 and a specificity of 0.38. Therefore, the proposed solution in the diabetes use case can result of utmost utility to secondary screening.
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Barrientos, L., Borja-Lloret, M., Casaña, J. V., Dendooven, P., Garcia Lopez, J. G., Hueso-Gonzalez, F., et al. (2024). Gamma-ray sources imaging and test-beam results with MACACO III Compton camera. Phys. Medica, 117, 103199–10pp.
Abstract: Hadron therapy is a radiotherapy modality which offers a precise energy deposition to the tumors and a dose reduction to healthy tissue as compared to conventional methods. However, methods for real-time monitoring are required to ensure that the radiation dose is deposited on the target. The IRIS group of IFIC-Valencia developed a Compton camera prototype for this purpose, intending to image the Prompt Gammas emitted by the tissue during irradiation. The system detectors are composed of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. After an initial characterization in the laboratory, in order to assess the system capabilities for future experiments in proton therapy centers, different tests were carried out in two facilities: PARTREC (Groningen, The Netherlands) and the CNA cyclotron (Sevilla, Spain). Characterization studies performed at PARTREC indicated that the detectors linearity was improved with respect to the previous version and an energy resolution of 5.2 % FWHM at 511 keV was achieved. Moreover, the imaging capabilities of the system were evaluated with a line source of 68Ge and a point-like source of 241Am-9Be. Images at 4.439 MeV were obtained from irradiation of a graphite target with an 18 MeV proton beam at CNA, to perform a study of the system potential to detect shifts at different intensities. In this sense, the system was able to distinguish 1 mm variations in the target position at different beam current intensities for measurement times of 1800 and 600 s.
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