Ballester, F., Granero, D., Perez-Calatayud, J., Venselaar, J. L. M., & Rivard, M. J. (2010). Study of encapsulated Tm-170 sources for their potential use in brachytherapy. Med. Phys., 37(4), 1629–1637.
Abstract: Methods: The authors have assumed a theoretical Tm-170 cylindrical source encapsulated with stainless steel and typical dimensions taken from the currently available HDR Ir-192 brachytherapy sources. The dose-rate distribution was calculated for this source using the GEANT4 Monte Carlo (MC) code considering both photon and electron Tm-170 spectra. The AAPM TG-43 U1 brachytherapy dosimetry parameters were derived. To study general properties of Tm-170 encapsulated sources, spherical sources encapsulated with stainless steel and platinum were also studied. Moreover, the influence of small variations in the active core and capsule dimensions on the dosimetric characteristics was assessed. Treatment times required for a Tm-170 source were compared to those for Ir-192 and Yb-169 for the same contained activity. Results: Due to the energetic beta spectrum and the large electron yield, the bremsstrahlung contribution to the dose was of the same order of magnitude as from the emitted gammas and characteristic x rays. Moreover, the electron spectrum contribution to the dose was significant up to 4 mm from the source center compared to the photon contribution. The dose-rate constant Lambda of the cylindrical source was 1.23 cGy h(-1) U-1. The behavior of the radial dose function showed promise for applications in brachytherapy. Due to the electron spectrum, the anisotropy was large for r < 6 mm. Variations in manufacturing tolerances did not significantly influence the final dosimetry data when expressed in cGy h(-1) U-1. For typical capsule dimensions, maximum reference dose rates of about 0.2, 10, and 2 Gy min(-1) would then be obtained for Tm-170, Ir-192, and Yb-169, respectively, resulting in treatment times greater than those for HDR Ir-192 brachytherapy. Conclusions: The dosimetric characteristics of source designs exploiting the low photon energy of Tm-170 were studied for potential application in HDR-brachytherapy. Dose-rate distributions were obtained for cylindrical and simplified spherical Tm-170 source designs (stainless steel and platinum capsule materials) using MC calculations. Despite the high activity of Tm-170, calculated treatment times were much longer than for Ir-192.
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Rivard, M. J., Granero, D., Perez-Calatayud, J., & Ballester, F. (2010). Influence of photon energy spectra from brachytherapy sources on Monte Carlo simulations of kerma and dose rates in water and air. Med. Phys., 37(2), 869–876.
Abstract: Methods: For Ir-192, I-125, and Pd-103, the authors considered from two to five published spectra. Spherical sources approximating common brachytherapy sources were assessed. Kerma and dose results from GEANT4, MCNP5, and PENELOPE-2008 were compared for water and air. The dosimetric influence of Ir-192, I-125, and Pd-103 spectral choice was determined. Results: For the spectra considered, there were no statistically significant differences between kerma or dose results based on Monte Carlo code choice when using the same spectrum. Water-kerma differences of about 2%, 2%, and 0.7% were observed due to spectrum choice for Ir-192, I-125, and Pd-103, respectively (independent of radial distance), when accounting for photon yield per Bq. Similar differences were observed for air-kerma rate. However, their ratio (as used in the dose-rate constant) did not significantly change when the various photon spectra were selected because the differences compensated each other when dividing dose rate by air-kerma strength. Conclusions: Given the standardization of radionuclide data available from the National Nuclear Data Center (NNDC) and the rigorous infrastructure for performing and maintaining the data set evaluations, NNDC spectra are suggested for brachytherapy simulations in medical physics applications.
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KM3NeT Collaboration(Aiello, S. et al), Alves Garre, S., Calvo, D., Carretero, V., Colomer, M., Corredoira, I., et al. (2021). Architecture and performance of the KM3NeT front-end firmware. J. Astron. Telesc. Instrum. Syst., 7(1), 016001–24pp.
Abstract: The KM3NeT infrastructure consists of two deep-sea neutrino telescopes being deployed in the Mediterranean Sea. The telescopes will detect extraterrestrial and atmospheric neutrinos by means of the incident photons induced by the passage of relativistic charged particles through the seawater as a consequence of a neutrino interaction. The telescopes are configured in a three-dimensional grid of digital optical modules, each hosting 31 photomultipliers. The photomultiplier signals produced by the incident Cherenkov photons are converted into digital information consisting of the integrated pulse duration and the time at which it surpasses a chosen threshold. The digitization is done by means of time to digital converters (TDCs) embedded in the field programmable gate array of the central logic board. Subsequently, a state machine formats the acquired data for its transmission to shore. We present the architecture and performance of the front-end firmware consisting of the TDCs and the state machine.
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Clausse, A., Soto, L., & Tarifeño-Saldivia, A. (2015). Influence of the Anode Length on the Neutron Emission of a 50 J Plasma Focus: Modeling and Experiment. IEEE Trans. Plasma Sci., 43(2), 629–636.
Abstract: A comprehensive set of electric data measured in a small plasma focus (PF) device of 50 J correlated with the corresponding neutron emissions is taken as the base for developing a semiempirical model of the current sheet dynamics and the neutron yield. The model is able to explain the dependence of the neutron yield with the pressure and anode length with good accuracy, and suggests a physical interpretation of the drive parameter commonly used in PF design.
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Real, D., Calvo, D., Diaz, A., Alves Garre, S., Carretero, V., Sanchez Losa, A., et al. (2023). An Ultra-Narrow Time Optical Pulse Emitter Based on a Laser: UNTOPEL. IEEE Trans. Nucl. Sci., 70(10), 2364–2372.
Abstract: Light sources that emit repetitive subnanosecond pulses are used in neutrino telescopes for time calibration. Optical pulses with an ultra-narrow (subnanosecond) width can replicate the light produced by neutrino interactions, and are an important calibration and test element. By measuring the time-of-flight of the light, it is possible to provide a relative time calibration for all the detector photomultipliers. This work presents the ultra-narrow time optical pulse emitter based on a laser (UNTOPEL), an instrument emitting ultra-short laser optical pulses with a duration of 500 ps, energies per pulse of four microjoules at a wavelength of 532 nm, and a timing precision of 400 ps. The UNTOPEL pulse intensity can be fine-tuned, which is a novelty and a significant advantage in those applications that need to illuminate light detectors located at different distances with the same light intensity. The UNTOPEL pulse intensity can be controlled remotely, allowing for its use in operating conditions where physical access is impossible or difficult. Moreover, it is easy to operate and can be easily controlled through an inter-integrated circuit bus. The UNTOPEL is a sound instrument used when subnanosecond pulses and variable energy emissions are needed.
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