Abstract: Compton imaging represents a promising technique for range verification in proton therapy treatments. In this work, we report on the advantageous aspects of the i-TED detector for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that have been specifically designed for neutron-capture nuclear physics experiments, which are characterized by gamma-ray energies spanning up to 5-6 MeV, rather low gamma-ray emission yields and very intense neutron induced gamma-ray backgrounds. Our developments to cope with these three aspects are concomitant with those required in the field of hadron therapy, especially in terms of high efficiency for real-time monitoring, low sensitivity to neutron backgrounds and reliable performance at the high gamma-ray energies. We find that signal-to-background ratios can be appreciably improved with i-TED thanks to its light-weight design and the low neutron-capture cross sections of its LaCl3 crystals, when compared to other similar systems based on LYSO, CdZnTe or LaBr3. Its high time-resolution (CRT similar to 500 ps) represents an additional advantage for background suppression when operated in pulsed HT mode. Each i-TED Compton module features two detection planes of very large LaCl3 monolithic crystals, thereby achieving a high efficiency in coincidence of 0.2% for a point-like 1 MeV gamma-ray source at 5 cm distance. This leads to sufficient statistics for reliable image reconstruction with an array of four i-TED detectors assuming clinical intensities of 10(8) protons per treatment point. The use of a two-plane design instead of three-planes has been preferred owing to the higher attainable efficiency for double time-coincidences than for threefold events. The loss of full-energy events for high energy gamma-rays is compensated by means of machine-learning based algorithms, which allow one to enhance the signal-to-total ratio up to a factor of 2.

Abstract: In light of the recent R-K(*) data on neutral current flavor anomalies in B -> K-(*())l(+)l(-) decays, we reexamine their quantitative interpretation in terms of an extended 331 gauge theory framework. We achieve this by adding two extra lepton species with novel 331 charges, while ensuring that the model remains anomaly-free. In contrast to the canonical 331 models, the gauge charges of the first and second lepton families differ from each other, allowing lepton-flavor universality violation. We further expand the model by adding the neutral fermions required to provide an adequate description for small neutrino masses.

Abstract: A search for the Higgs boson decaying into a pair of charm quarks is presented. The analysis uses proton- proton collisions to target the production of a Higgs boson in association with a leptonically decaying W or Z boson. The dataset delivered by the LHC at a centre-of-mass energy of root s = 13 TeV and recorded by the ATLAS detector corresponds to an integrated luminosity of 139 fb(-1). Flavour-tagging algorithms are used to identify jets originating from the hadronisation of charm quarks. The analysis method is validated with the simultaneous measurement of WW, WZ and ZZ production, with observed (expected) significances of 2.6 (2.2) standard deviations above the background-only prediction for the (W/Z)Z(-> c (c) over bar) process and 3.8 (4.6) standard deviations for the (W/Z)W(-> cq) process. The (WIZ)H(-> c (c) over bar) search yields an observed (expected) upper limit of 26 (31) times the predicted Standard Model crosssection times branching fraction for a Higgs boson with a mass of 125 GeV, corresponding to an observed (expected) constraint on the charm Yukawa coupling modifier vertical bar k(c)vertical bar < 8.5 (12.4), at the 95% confidence level. A combination with the ATLAS (W/Z)H, H -> b<(b)over bar> analysis is performed, allowing the ratio k(c)/k(b) to be constrained to less than 4.5 at the 95% confidence level, smaller than the ratio of the b- and c-quark masses, and therefore determines the Higgs-charm coupling to be weaker than the Higgs-bottom coupling at the 95% confidence level.

Abstract: A search for the decay B-0 -> phi mu(+) mu(-) is performed using proton-proton collisions at centre-of-mass energies of 7, 8, and 13 TeV collected by the LHCb experiment and corresponding to an integrated luminosity of 9 fb(-1). No evidence for the B-0 -> phi mu(+) mu(-) decay is found and an upper limit on the branching fraction, excluding the 0 and charmonium regions in the dimuon spectrum, of 4.4 x 10(-3) at a 90% credibility level, relative to that of the B-s(0) -> phi mu(+) mu(-) decay, is established. Using the measured B-s(0) -> phi mu(+) mu(-) branching fraction and assuming a phase-space model, the absolute branching fraction of the decay B-0 -> phi mu(+) mu(-) in the full q(2) range is determined to be less than 3.2 x 10(-9) at a 90% credibility level.

Abstract: We investigate the sensitivity of the Laser Interferometer Space Antenna (LISA) to the anisotropies of the Stochastic Gravitational Wave Background (SGWB). We first discuss the main astrophysical and cosmological sources of SGWB which are characterized by anisotropies in the GW energy density, and we build a Signal-to-Noise estimator to quantify the sensitivity of LISA to different multipoles. We then perform a Fisher matrix analysis of the prospects of detectability of anisotropic features with LISA for individual multipoles, focusing on a SGWB with a power-law frequency profile. We compute the noise angular spectrum taking into account the specific scan strategy of the LISA detector. We analyze the case of the kinematic dipole and quadrupole generated by Doppler boosting an isotropic SGWB. We find that beta Omega(GW) similar to 2 x 10(-11) is required to observe a dipolar signal with LISA. The detector response to the quadrupole has a factor similar to 10(3) beta relative to that of the dipole. The characterization of the anisotropies, both from a theoretical perspective and from a map-making point of view, allows us to extract information that can be used to understand the origin of the SGWB, and to discriminate among distinct superimposed SGWB sources.