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Records |
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Author |
ANTARES Collaboration (Tamburini, C. et al); Aguilar, J.A.; Bigongiari, C.; Dornic, D.; Emanuele, U.; Gomez-Gonzalez, J.P.; Hernandez-Rey, J.J.; Mangano, S.; Ruiz-Rivas, J.; Salesa, F.; Sanchez-Losa, A.; Toscano, S.; Yepes, H.; Zornoza, J.D.; Zuñiga, J. |
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Title |
Deep-Sea Bioluminescence Blooms after Dense Water Formation at the Ocean Surface |
Type |
Journal Article |
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Year |
2013 |
Publication |
Plos One |
Abbreviated Journal |
PLoS One |
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Volume |
8 |
Issue |
7 |
Pages |
e67523 - 10pp |
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Keywords |
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Abstract |
The deep ocean is the largest and least known ecosystem on Earth. It hosts numerous pelagic organisms, most of which are able to emit light. Here we present a unique data set consisting of a 2.5-year long record of light emission by deep-sea pelagic organisms, measured from December 2007 to June 2010 at the ANTARES underwater neutrino telescope in the deep NW Mediterranean Sea, jointly with synchronous hydrological records. This is the longest continuous time-series of deep-sea bioluminescence ever recorded. Our record reveals several weeks long, seasonal bioluminescence blooms with light intensity up to two orders of magnitude higher than background values, which correlate to changes in the properties of deep waters. Such changes are triggered by the winter cooling and evaporation experienced by the upper ocean layer in the Gulf of Lion that leads to the formation and subsequent sinking of dense water through a process known as “open-sea convection”. It episodically renews the deep water of the study area and conveys fresh organic matter that fuels the deep ecosystems. Luminous bacteria most likely are the main contributors to the observed deep-sea bioluminescence blooms. Our observations demonstrate a consistent and rapid connection between deep open-sea convection and bathypelagic biological activity, as expressed by bioluminescence. In a setting where dense water formation events are likely to decline under global warming scenarios enhancing ocean stratification, in situ observatories become essential as environmental sentinels for the monitoring and understanding of deep-sea ecosystem shifts. |
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Address |
[Tamburini, Christian; Lefevre, Dominique; Martini, Verine; Robert, Anne; Dekeyser, Ivan; Fuda, Jean-Luc] Aix Marseille Univ, CNRS INSU, IRD, MIO,U110, Marseille, France, Email: christian.tamburini@univ-amu.fr; |
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Public Library Science |
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English |
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ISSN |
1932-6203 |
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Notes |
WOS:000321765300012 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1496 |
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Author |
Sanjuan, R.; Nebot, M.; Peris, J.B.; Alcami, J. |
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Title |
Immune Activation Promotes Evolutionary Conservation of T-Cell Epitopes in HIV-1 |
Type |
Journal Article |
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Year |
2013 |
Publication |
Plos Biology |
Abbreviated Journal |
PLoS. Biol. |
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Volume |
11 |
Issue |
4 |
Pages |
e1001523 - 10pp |
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Keywords |
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Abstract |
The immune system should constitute a strong selective pressure promoting viral genetic diversity and evolution. However, HIV shows lower sequence variability at T-cell epitopes than elsewhere in the genome, in contrast with other human RNA viruses. Here, we propose that epitope conservation is a consequence of the particular interactions established between HIV and the immune system. On one hand, epitope recognition triggers an anti-HIV response mediated by cytotoxic T-lymphocytes (CTLs), but on the other hand, activation of CD4(+) helper T lymphocytes (T-H cells) promotes HIV replication. Mathematical modeling of these opposite selective forces revealed that selection at the intrapatient level can promote either T-cell epitope conservation or escape. We predict greater conservation for epitopes contributing significantly to total immune activation levels (immunodominance), and when T-H cell infection is concomitant to epitope recognition (transinfection). We suggest that HIV-driven immune activation in the lymph nodes during the chronic stage of the disease may offer a favorable scenario for epitope conservation. Our results also support the view that some pathogens draw benefits from the immune response and suggest that vaccination strategies based on conserved T-H epitopes may be counterproductive. |
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Address |
Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolut, Valencia, Spain, Email: rafael.sanjuan@uv.es |
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Public Library Science |
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English |
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ISSN |
1545-7885 |
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Notes |
WOS:000318687800003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
1446 |
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Author |
n_TOF Collaboration (Barbagallo, M. et al); Domingo-Pardo, C.; Giubrone, G.; Tain, J.L. |
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Title |
High-accuracy determination of the neutron flux at n_TOF |
Type |
Journal Article |
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Year |
2013 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
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Volume |
49 |
Issue |
12 |
Pages |
156 - 11pp |
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Abstract |
The neutron flux of the nTOF facility at CERN was measured, after installation of the new spallation target, with four different systems based on three neutron-converting reactions, which represent accepted cross sections standards in different energy regions. A careful comparison and combination of the different measurements allowed us to reach an unprecedented accuracy on the energy dependence of the neutron flux in the very wide range (thermal to 1 GeV) that characterizes the nTOF neutron beam. This is a pre-requisite for the high accuracy of cross section measurements at n_TOF. An unexpected anomaly in the neutron-induced fission cross section of U-235 is observed in the energy region between 10 and 30keV, hinting at a possible overestimation of this important cross section, well above currently assigned uncertainties. |
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Address |
[Barbagallo, M.; Colonna, N.; Mastromarco, M.; Meaze, M.; Tagliente, G.; Variale, V.] Ist Nazl Fis Nucl, Sez Bari, I-70125 Bari, Italy, Email: massimo.barbagallo@ba.infn.it |
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Springer |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6001 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000328351000001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1663 |
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Author |
HADES Collaboration (Agakishiev, G. et al); Diaz, J.; Gil, A. |
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Title |
Deep sub-threshold K*(892)(0) production in collisions of Ar + KCl at 1.76A GeV |
Type |
Journal Article |
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Year |
2013 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
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Volume |
49 |
Issue |
3 |
Pages |
34 - 7pp |
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Abstract |
Results on the deep sub-threshold production of the short-lived hadronic resonance K*(892)(0) are reported for collisions of Ar + KCl at 1.76 A GeV beam energy, studied with the High Acceptance Di-Electron Spectrometer (HADES) at SIS18/GSI. The K*(892)(0) production probability per central collision of P-K*0 = (4.4 +/- 1.1 +/- 0.5) x 10(-4) and the K*(892)(0)/K-0 ratio of P-K*0/P-K0 = (1.9 +/- 0.5 +/- 0.3) x 10(-2) are determined at the lowest energy so far (i.e. deep below the threshold for the corresponding production in nucleon-nucleon collisions, root s(NN)-root s(thr) = -340MeV). The K*(0)/K-0 ratio is compared with results of other experiments and with the predictions of the UrQMD transport approach and of the statistical hadronization model. The experimental K*(0) yield and the K-*0/K-0 ratio are overestimated by the transport model by factors of about five and two, respectively. In a chemically equilibrated medium the ratio corresponds to a temperature of the thermalized system being systematically lower than the value determined by the yields of the stable and long-lived hadrons produced in Ar + KCl collisions. From the present measurement, we conclude that sub-threshold K* production either cannot be considered to proceed in a system being in thermal equilibrium or these short-lived resonances appear undersaturated, for example as a result of the rescattering of the decay particles in the ambient hadronic medium. |
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Address |
Inst Nazl Fis Nucl, Lab Nazl Sud, I-95125 Catania, Italy, Email: kotte@hzdr.de |
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Springer |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6001 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000317855000006 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1426 |
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Author |
n_TOF Collaboration (Guerrero, C. et al); Domingo-Pardo, C.; Giubrone, G.; Tain, J.L. |
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Title |
Performance of the neutron time-of-flight facility n_TOF at CERN |
Type |
Journal Article |
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Year |
2013 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
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Volume |
49 |
Issue |
2 |
Pages |
27 - 15pp |
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Keywords |
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Abstract |
The neutron time-of-flight facility n_TOF features a white neutron source produced by spallation through 20 GeV/c protons impinging on a lead target. The facility, aiming primarily at the measurement of neutron-induced reaction cross sections, was operating at CERN between 2001 and 2004, and then underwent a major upgrade in 2008. This paper presents in detail all the characteristics of the new neutron beam in the currently available configurations, which correspond to two different collimation systems and two choices of neutron moderator. The characteristics discussed include the intensity and energy dependence of the neutron flux, the spatial profile of the beam, the in-beam background components and the energy resolution/broadening. The discussion of these features is based on dedicated measurements and Monte Carlo simulations, and includes estimations of the systematic uncertainties of the mentioned quantities. |
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Address |
[Guerrero, C.; Tsinganis, A.; Berthoumieux, E.; Weiss, C.; Chiaveri, E.; Calviani, M.; Vlachoudis, V.; Andriamonje, S.; Boccone, V.; Brugger, M.; Cerutti, F.; Chin, M.; Ferrari, A.; Hernandez-Prieto, A.; Kadi, Y.; Losito, R.; Roman, F.; Rubbia, C.; Versaci, R.] CERN, European Org Nucl Res, CH-1211 Geneva, Switzerland, Email: carlos.guerrero@cern.ch |
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Corporate Author |
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Thesis |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6001 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000315601600011 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1358 |
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| Permanent link to this record |
