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Menendez, A., Esperante, D., Garcia-Olcina, R., Torres, J., Perez-Soler, J., Marco, R., et al. (2022). RF Acquisition System Based on μTCA for Testing of High-Gradient Acceleration Cavities. Electronics, 11(5), 720–22pp.
Abstract: The radio frequency (RF) laboratory hosted in the Corpuscular Physics Institute (IFIC) of the University of Valencia is designed to house a high-power and high-repetition-rate facility to test normal conduction RF accelerator cavities in the S-Band (2.9985 GHz) in order to perform R & D activities related to particle accelerator cavities. The system, which manages the entire process of RF signal generation, data acquisition and closed-loop control of the laboratory, is currently based on a modular and compact PXI platform system. This contribution details the development of a platform with similar features, but which is based on open architecture standards at both the hardware and software level. For this purpose, a complete system based on the μTCA platform has been developed. This new system must be able to work with accelerator cavities at other operating frequencies, such as 750 MHz, as well as to explore different options at firmware and software levels based on open-source codes.
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Oliver-Canamas, L., Vijande, J., Candela-Juan, C., Gimeno-Olmos, J., Pujades-Claumarchirant, M. C., Rovira-Escutia, J. J., et al. (2023). A User-Friendly System for Mailed Dosimetric Audits of Ir-192 or Co-60 HDR Brachytherapy Sources. Cancers, 15(9), 2484–14pp.
Abstract: Nowadays, the options available to perform external dosimetric audits of the high dose rate (HDR) brachytherapy treatment process are limited. In this work, we present a methodology that allows for performing dosimetric audits in this field. A phantom was designed and manufactured for this purpose. The criteria for its design, together with the in-house measurements for its characterization, are presented. The result is a user-friendly system that can be mailed to perform dosimetric audits in HDR brachytherapy on-site for systems using either Iridium-192 (Ir-192) or Cobalt-60 (Co-60) sources. Objectives: The main goal of this work is to design and characterize a user-friendly methodology to perform mailed dosimetric audits in high dose rate (HDR) brachytherapy for systems using either Iridium-192 (Ir-192) or Cobalt-60 (Co-60) sources. Methods: A solid phantom was designed and manufactured with four catheters and a central slot to place one dosimeter. Irradiations with an Elekta MicroSelectron V2 for Ir-192, and with a BEBIG Multisource for Co-60 were performed for its characterization. For the dose measurements, nanoDots, a type of optically stimulated luminescent dosimeters (OSLDs), were characterized. Monte Carlo (MC) simulations were performed to evaluate the scatter conditions of the irradiation set-up and to study differences in the photon spectra of different Ir-192 sources (Microselectron V2, Flexisource, BEBIG Ir2.A85-2 and Varisource VS2000) reaching the dosimeter in the irradiation set-up. Results: MC simulations indicate that the surface material on which the phantom is supported during the irradiations does not affect the absorbed dose in the nanoDot. Generally, differences below 5% were found in the photon spectra reaching the detector when comparing the Microselectron V2, the Flexisource and the BEBIG models. However, differences up to 20% are observed between the V2 and the Varisource VS2000 models. The calibration coefficients and the uncertainty in the dose measurement were evaluated. Conclusions: The system described here is able to perform dosimetric audits in HDR brachytherapy for systems using either Ir-192 or Co-60 sources. No significant differences are observed between the photon spectra reaching the detector for the MicroSelectron V2, the Flexisource and the BEBIG Ir-192 sources. For the Varisource VS2000, a higher uncertainty is considered in the dose measurement to allow for the nanoDot response.
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Otal, A., Celada, F., Chimeno, J., Vijande, J., Pellejero, S., Perez-Calatayud, M. J., et al. (2022). Review on Treatment Planning Systems for Cervix Brachytherapy (Interventional Radiotherapy): Some Desirable and Convenient Practical Aspects to Be Implemented from Radiation Oncologist and Medical Physics Perspectives. Cancers, 14(14), 3467–15pp.
Abstract: Simple Summary There are no brachytherapy treatment planning systems (TPS) exclusively for the treatment of cervical tumours, so general-purpose TPSs are used. However, these treatments have some particular features concerning the treatment of other pathologies, especially in the case of exclusive use of MRI as an imaging modality and the presence of gynaecological applicators in combination with an interstitial part. That is why it is essential to review the latest versions of commercial TPSs to find the potential features to improve with the help of a group of experimented medical physicists and radiation oncologists. Furthermore, after reviewing the recent literature for advances applicable to cervical brachytherapy and through his own clinical experience, possible improvements are proposed to software providers for the development of new tools. Intracavitary brachytherapy (BT, Interventional Radiotherapy, IRT), plays an essential role in the curative intent of locally advanced cervical cancer, for which the conventional approach involves external beam radiotherapy with concurrent chemotherapy followed by BT. This work aims to review the different methodologies used by commercially available treatment planning systems (TPSs) in exclusive magnetic resonance imaging-based (MRI) cervix BT with interstitial component treatments. Practical aspects and improvements to be implemented into the TPSs are discussed. This review is based on the clinical expertise of a group of radiation oncologists and medical physicists and on interactive demos provided by the software manufacturers. The TPS versions considered include all the new tools currently in development for future commercial releases. The specialists from the supplier companies were asked to propose solutions to some of the challenges often encountered in a clinical environment through a questionnaire. The results include not only such answers but also comments by the authors that, in their opinion, could help solve the challenges covered in these questions. This study summarizes the possibilities offered nowadays by commercial TPSs, highlighting the absence of some useful tools that would notably improve the planning of MR-based interstitial component cervix brachytherapy.
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Real, D., Sanchez Losa, A., Diaz, A., Salesa Greus, F., & Calvo, D. (2023). The Neutrino Mediterranean Observatory Laser Beacon: Design and Qualification. Appl. Sci.-Basel, 13(17), 9935–16pp.
Abstract: This paper encapsulates details of the NEMO laser beacon's design, offering a profound contribution to the field of the time calibration of underwater neutrino telescopes. The mechanical design of the laser beacon, which operates at a depth of 3500 m, is presented, together with the design of the antibiofouling system employed to endure the operational pressure and optimize the operational range, enhancing its functionality and enabling time calibration among multiple towers. A noteworthy innovation central to this development lies in the battery system. This configuration enhances the device's portability, a crucial aspect in underwater operations. The comprehensive design of the laser beacon, encompassing the container housing, the requisite battery system for operation, electronics, and an effective antibiofouling system, is described in this paper. Additionally, this paper presents the findings of the laser beacon's qualification process.
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Olivares Herrador, J., Latina, A., Aksoy, A., Fuster Martinez, N., Gimeno, B., & Esperante, D. (2024). Implementation of the beam-loading effect in the tracking code RF-track based on a power-diffusive model. Front. Physics, 12, 1348042–11pp.
Abstract: The need to achieve high energies in particle accelerators has led to the development of new accelerator technologies, resulting in higher beam intensities and more compact devices with stronger accelerating fields. In such scenarios, beam-loading effects occur, and intensity-dependent gradient reduction affects the accelerated beam as a consequence of its interaction with the surrounding cavity. In this study, a power-diffusive partial differential equation is derived to account for this effect. Its numerical resolution has been implemented in the tracking code RF-Track, allowing the simulation of apparatuses where transient beam loading plays an important role. Finally, measurements of this effect have been carried out in the CERN Linear Electron Accelerator for Research (CLEAR) facility at CERN, finding good agreement with the RF-Track simulations.
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