Abstract: The production of psi(2S) mesons in proton-lead collisions at a centre-of-mass energy per nucleon pair of root s(NN) = 8.16TeV is studied with the LHCb detector using data corresponding to an integrated luminosity of 34 nb(-1). The prompt and nonprompt psi(2S) production cross-sections and the ratio of the psi(2S) to J/psi cross-section are measured as a function of the meson transverse momentum and rapidity in the nucleon-nucleon centre-of-mass frame, together with forward-to-backward ratios and nuclear modification factors. The production of prompt psi(2S) is observed to be more suppressed compared to pp collisions than the prompt J/psi production, while the nonprompt productions have similar suppression factors.

Abstract: In this article we study the phenomenological implications of multiple Higgs boson production from longitudinal vector boson scattering in the context of effective field theories. We find compact representations for effective tree-level amplitudes with up to four final state Higgs bosons. Total cross sections are then computed for scenarios relevant at the LHC in which we find the general Higgs Effective Theory (HEFT) prediction avoids the heavy suppression observed in Standard Model Effective Field Theory (SMEFT).

Abstract: Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range.