Double Chooz collaboration(Abrahao, T. et al), & Novella, P. (2021). Reactor rate modulation oscillation analysis with two detectors in Double Chooz. J. High Energy Phys., 01(1), 190–18pp.
Abstract: A theta (13) oscillation analysis based on the observed antineutrino rates at the Double Chooz far and near detectors for different reactor power conditions is presented. This approach provides a so far unique simultaneous determination of theta (13) and the total background rates without relying on any assumptions on the specific background contributions. The analysis comprises 865 days of data collected in both detectors with at least one reactor in operation. The oscillation results are enhanced by the use of 24.06 days (12.74 days) of reactor-off data in the far (near) detector. The analysis considers the nu <mml:mo stretchy=“true”><overbar></mml:mover>e interactions up to a visible energy of 8.5 MeV, using the events at higher energies to build a cosmogenic background model considering fast-neutrons interactions and Li-9 decays. The background-model-independent determination of the mixing angle yields sin(2)(2 theta (13)) = 0.094 0.017, being the best-fit total background rates fully consistent with the cosmogenic background model. A second oscillation analysis is also performed constraining the total background rates to the cosmogenic background estimates. While the central value is not significantly modified due to the consistency between the reactor-off data and the background estimates, the addition of the background model reduces the uncertainty on theta (13) to 0.015. Along with the oscillation results, the normalization of the anti-neutrino rate is measured with a precision of 0.86%, reducing the 1.43% uncertainty associated to the expectation.
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Di Gregorio, E., Staelens, M., Hosseinkhah, N., Karimpoor, M., Liburd, J., Lim, L., et al. (2024). Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer's and Other Neurodegenerative Diseases. Nanomaterials, 14(13), 1093–21pp.
Abstract: In small clinical studies, the application of transcranial photobiomodulation (PBM), which typically delivers low-intensity near-infrared (NIR) to treat the brain, has led to some remarkable results in the treatment of dementia and several neurodegenerative diseases. However, despite the extensive literature detailing the mechanisms of action underlying PBM outcomes, the specific mechanisms affecting neurodegenerative diseases are not entirely clear. While large clinical trials are warranted to validate these findings, evidence of the mechanisms can explain and thus provide credible support for PBM as a potential treatment for these diseases. Tubulin and its polymerized state of microtubules have been known to play important roles in the pathology of Alzheimer's and other neurodegenerative diseases. Thus, we investigated the effects of PBM on these cellular structures in the quest for insights into the underlying therapeutic mechanisms. In this study, we employed a Raman spectroscopic analysis of the amide I band of polymerized samples of tubulin exposed to pulsed low-intensity NIR radiation (810 nm, 10 Hz, 22.5 J/cm2 dose). Peaks in the Raman fingerprint region (300-1900 cm-1)-in particular, in the amide I band (1600-1700 cm-1)-were used to quantify the percentage of protein secondary structures. Under this band, hidden signals of C=O stretching, belonging to different structures, are superimposed, producing a complex signal as a result. An accurate decomposition of the amide I band is therefore required for the reliable analysis of the conformation of proteins, which we achieved through a straightforward method employing a Voigt profile. This approach was validated through secondary structure analyses of unexposed control samples, for which comparisons with other values available in the literature could be conducted. Subsequently, using this validated method, we present novel findings of statistically significant alterations in the secondary structures of polymerized NIR-exposed tubulin, characterized by a notable decrease in alpha-helix content and a concurrent increase in beta-sheets compared to the control samples. This PBM-induced alpha-helix to beta-sheet transition connects to reduced microtubule stability and the introduction of dynamism to allow for the remodeling and, consequently, refreshing of microtubule structures. This newly discovered mechanism could have implications for reducing the risks associated with brain aging, including neurodegenerative diseases like Alzheimer's disease, through the introduction of an intervention following this transition.
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Perez-Perez, J., Amare, J. C., Bandac, I. C., Bayo, A., Borjabad-Sanchez, S., Calvo-Mozota, J. M., et al. (2022). Radon Mitigation Applications at the Laboratorio Subterráneo de Canfranc (LSC). Universe, 8(2), 112–20pp.
Abstract: The Laboratorio Subterraneo de Canfranc (LSC) is the Spanish national hub for low radioactivity techniques and the associated scientific and technological applications. The concentration of the airborne radon is a major component of the radioactive budget in the neighborhood of the detectors. The LSC hosts a Radon Abatement System, which delivers a radon suppressed air with 1.1 & PLUSMN;0.2 mBq/m(3) of Rn-222. The radon content in the air is continuously monitored with an Electrostatic Radon Monitor. Measurements with the double beta decay demonstrators NEXT-NEW and CROSS and the gamma HPGe detectors show the important reduction of the radioactive background due to the purified air in the vicinity of the detectors. We also discuss the use of this facility in the LSC current program which includes NEXT-100, low background biology experiments and radiopure copper electroformation equipment placed in the radon-free clean room.
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NEXT Collaboration(Alvarez, V. et al), Carcel, S., Cervera-Villanueva, A., Diaz, J., Ferrario, P., Gil, A., et al. (2013). Radiopurity control in the NEXT-100 double beta decay experiment: procedures and initial measurements. J. Instrum., 8, T01002–19pp.
Abstract: The “Neutrino Experiment with a Xenon Time-Projection Chamber” (NEXT) is intended to investigate the neutrinoless double beta decay of Xe-136, which requires a severe suppression of potential backgrounds. An extensive screening and material selection process is underway for NEXT since the control of the radiopurity levels of the materials to be used in the experimental set-up is a must for rare event searches. First measurements based on Glow Discharge Mass Spectrometry and gamma-ray spectroscopy using ultra-low background germanium detectors at the Laboratorio Subterraneo de Canfranc (Spain) are described here. Activity results for natural radioactive chains and other common radionuclides are summarized, being the values obtained for some materials like copper and stainless steel very competitive. The implications of these results for the NEXT experiment are also discussed.
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NEXT Collaboration(Cebrian, S. et al), Alvarez, V., Carcel, S., Cervera-Villanueva, A., Diaz, J., Ferrario, P., et al. (2015). Radiopurity assessment of the tracking readout for the NEXT double beta decay experiment. J. Instrum., 10, P05006–16pp.
Abstract: The “Neutrino Experiment with a Xenon Time-Projection Chamber” (NEXT) is intended to investigate the neutrinoless double beta decay of Xe-136, which requires a severe suppression of potential backgrounds; therefore, an extensive screening and selection process is underway to control the radiopurity levels of the materials to be used in the experimental set-up of NEXT. The detector design combines the measurement of the topological signature of the event for background discrimination with the energy resolution optimization. Separate energy and tracking readout planes are based on different sensors: photomultiplier tubes for calorimetry and silicon multi-pixel photon counters for tracking. The design of a radiopure tracking plane, in direct contact with the gas detector medium, was specially challenging since the needed components like printed circuit boards, connectors, sensors or capacitors have typically, according to available information in databases and in the literature, activities too large for experiments requiring ultra-low background conditions. Here, the radiopurity assessment of tracking readout components based on gamma-ray spectroscopy using ultra-low background germanium detectors at the Laboratorio Subterraneo de Canfranc (Spain) is described. According to the obtained results, radiopure enough printed circuit boards made of kapton and copper, silicon photomultipliers and other required components, fulfilling the requirement of an overall background level in the region of interest of at most 8 x 10(-4) counts keV(-1) kg(-1) y(-1), have been identified.
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NEXT Collaboration(Cebrian, S. et al), Perez, J., Alvarez, V., Benlloch-Rodriguez, J., Botas, A., Carcel, S., et al. (2017). Radiopurity assessment of the energy readout for the NEXT double beta decay experiment. J. Instrum., 12, T08003–20pp.
Abstract: The “Neutrino Experiment with a Xenon Time-Projection Chamber” (NEXT) experiment intends to investigate the neutrinoless double beta decay of Xe-136, and therefore requires a severe suppression of potential backgrounds. An extensive material screening and selection process was undertaken to quantify the radioactivity of the materials used in the experiment. Separate energy and tracking readout planes using different sensors allow us to combine the measurement of the topological signature of the event for background discrimination with the energy resolution optimization. The design of radiopure readout planes, in direct contact with the gas detector medium, was especially challenging since the required components typically have activities too large for experiments demanding ultra-low background conditions. After studying the tracking plane, here the radiopurity control of the energy plane is presented, mainly based on gamma-ray spectroscopy using ultra-low background germanium detectors at the Laboratorio Subterraneo de Canfranc (Spain). All the available units of the selected model of photomultiplier have been screened together with most of the components for the bases, enclosures and windows. According to these results for the activity of the relevant radioisotopes, the selected components of the energy plane would give a contribution to the overall background level in the region of interest of at most 2.4 x 10(-4) counts keV(-1) kg(-1) y(-1), satisfying the sensitivity requirements of the NEXT experiment.
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NEXT Collaboration(Woodruff, K. et al), Alvarez, V., Benlloch-Rodriguez, J. M., Carcel, S., Carrion, J. V., Diaz, J., et al. (2020). Radio frequency and DC high voltage breakdown of high pressure helium, argon, and xenon. J. Instrum., 15(4), P04022–15pp.
Abstract: Motivated by the possibility of guiding daughter ions from double beta decay events to single-ion sensors for barium tagging, the NEXT collaboration is developing a program of R&D to test radio frequency (RF) carpets for ion transport in high pressure xenon gas. This would require carpet functionality in regimes at higher pressures than have been previously reported, implying correspondingly larger electrode voltages than in existing systems. This mode of operation appears plausible for contemporary RF-carpet geometries due to the higher predicted breakdown strength of high pressure xenon relative to low pressure helium, the working medium in most existing RF carpet devices. In this paper we present the first measurements of the high voltage dielectric strength of xenon gas at high pressure and at the relevant RF frequencies for ion transport (in the 10MHz range), as well as new DC and RF measurements of the dielectric strengths of high pressure argon and helium gases at small gap sizes. We find breakdown voltages that are compatible with stable RF carpet operation given the gas, pressure, voltage, materials and geometry of interest.
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n_TOF Collaboration(Gawlik, A. et al), Domingo-Pardo, C., Tain, J. L., & Tarifeño-Saldivia, A. (2021). Radiative Neutron Capture Cross-Section Measurement of Ge Isotopes at n_TOF CERN Facility and Its Importance for Stellar Nucleosynthesis. Acta Phys. Pol. A, 139(4), 383–388.
Abstract: This manuscript summarizes the results of radiative neutron capture cross-section measurements on two stable germanium isotopes, Ge-70 and Ge-73. Experiments were performed at the n_TOF facility at CERN via the time-of-flight technique, over a wide neutron energy range, for all stable germanium isotopes (70,72,73,74, and 76). Results for Ge-70 [Phys. Rev. C 100, 045804 (2019)] and Ge-73 [Phys. Lett. B 790, 458 (2019)] are already published. In the field of nuclear structure, such measurements allow to study excited levels close to the neutron binding energy and to obtain information on nuclear properties. In stellar nucleosynthesis research, neutron induced reactions on germanium are of importance for nucleosynthesis in the weak component of the slow neutron capture processes.
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Miñano, M. (2011). Radiation Hard Silicon Strips Detectors for the SLHC. IEEE Trans. Nucl. Sci., 58(3), 1135–1140.
Abstract: While the Large Hadron Collider (LHC) began taking data in 2009, scenarios for a machine upgrade to achieve a much higher luminosity are being developed. In the current planning, it is foreseen to increase the luminosity of the LHC at CERN around 2018. As radiation damage scales with integrated luminosity, the particle physics experiments will need to be equipped with a new generation of radiation hard detectors. This article reports on the status of the R&D projects on radiation hard silicon strips detectors for particle physics, linked to the Large Hadron Collider Upgrade, super-LHC (sLHC) of the ATLAS microstrip detector. The primary focus of this report is on measuring the radiation hardness of the silicon materials and the detectors under study. This involves designing silicon detectors, irradiating them to the sLHC radiation levels and studying their performance as particle detectors. The most promising silicon detector for the different radiation levels in the different regions of the ATLAS microstrip detector will be presented. Important challenges related to engineering layout, powering, cooling and reading out a very large strip detector are presented. Ideas on possible schemes for the layout and support mechanics will be shown.
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Boudet, S., Bombacigno, F., Olmo, G. J., & Porfirio, P. (2022). Quasinormal modes of Schwarzschild black holes in projective invariant Chern-Simons modified gravity. J. Cosmol. Astropart. Phys., 05(5), 032–29pp.
Abstract: We generalize the Chern-Simons modified gravity to the metric-affine case and impose projective invariance by supplementing the Pontryagin density with homothetic curvature terms which do not spoil topologicity. The latter is then broken by promoting the coupling of the Chern-Simons term to a (pseudo)-scalar field. The solutions for torsion and nonmetricity are derived perturbatively, showing that they can be iteratively obtained from the background fields. This allows us to describe the dynamics for the metric and the scalar field perturbations in a self-consistent way, and we apply the formalism to the study of quasi normal modes in a Schwarzschild black hole background. Unlike in the metric formulation of this theory, we show that the scalar field is endowed with dynamics even in the absence of its kinetic term in the action. Finally, using numerical methods we compute the quasinormal frequencies and characterize the late-time power law tails for scalar and metric perturbations, comparing the results with the outcomes of the purely metric approach.
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