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Author |
Borys, D. et al; Brzezinski, K. |
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Title  |
ProTheRaMon-a GATE simulation framework for proton therapy range monitoring using PET imaging |
Type |
Journal Article |
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Year |
2022 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
67 |
Issue |
22 |
Pages |
224002 - 15pp |
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Keywords |
proton therapy; GATE; Monte Carlo simulations; J-PET; medical imaging |
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Abstract |
Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). ProTheRaMon offers complete processing of proton therapy treatment plans, patient CT geometries, and intra-treatment PET imaging, taking into account therapy and imaging coordinate systems and activity decay during the PET imaging protocol specific to a given proton therapy facility. We present the ProTheRaMon framework and illustrate its potential use case and data processing steps for a patient treated at the Cyclotron Centre Bronowice (CCB) proton therapy center in Krakow, Poland. Approach. The ProTheRaMon framework is based on GATE Monte Carlo software, the CASToR reconstruction package and in-house developed Python and bash scripts. The framework consists of five separated simulation and data processing steps, that can be further optimized according to the user's needs and specific settings of a given proton therapy facility and PET scanner design. Main results. ProTheRaMon is presented using example data from a patient treated at CCB and the J-PET scanner to demonstrate the application of the framework for proton therapy range monitoring. The output of each simulation and data processing stage is described and visualized. Significance. We demonstrate that the ProTheRaMon simulation platform is a high-performance tool, capable of running on a computational cluster and suitable for multi-parameter studies, with databases consisting of large number of patients, as well as different PET scanner geometries and settings for range monitoring in a clinical environment. Due to its modular structure, the ProTheRaMon framework can be adjusted for different proton therapy centers and/or different PET detector geometries. It is available to the community via github (Borys et al 2022). |
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Address |
[Borys, Damian] Silesian Tech Univ, Dept Syst Biol & Engn, Gliwice, Poland, Email: damin.borys@polsl.pl |
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Publisher |
IOP Publishing Ltd |
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English |
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ISSN |
0031-9155 |
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Conference |
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Notes |
WOS:000885248200001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5416 |
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Author |
Sieber, H.; Banerjee, D.; Crivelli, P.; Depero, E.; Gninenko, S.N.; Kirpichnikov, D.V.; Kirsanov, M.M.; Poliakov, V.; Molina Bueno, L. |
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Title |
Prospects in the search for a new light Z0 boson with the NA64 μexperiment at the CERN SPS |
Type |
Journal Article |
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Year |
2022 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
105 |
Issue |
5 |
Pages |
052006 - 9pp |
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Keywords |
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Abstract |
A light Z0 vector boson coupled to the second and third lepton generations through the L μ- L tau current with mass below 200 MeV provides a very viable explanation in terms of new physics to the recently confirmed og – 2 thorn μanomaly. This boson can be produced in the bremsstrahlung reaction μN – μNZ0 after a high energy muon beam collides with a target. NA64 μis a fixed-target experiment using a 160 GeV muon beam from the CERN Super Proton Synchrotron accelerator looking for Z0 production and its subsequent decays, Z0 – invisible. In this paper, we present the study of the NA64 μsensitivity to search for such a boson. This includes a realistic beam simulation, a detailed description of the detectors and a discussion about the main potential background sources. A pilot run is scheduled in order to validate the simulation results. If those are confirmed, NA64 μwill be able to explore all the remaining parameter space which could provide an explanation for the g – 2 muon anomaly in the L μ- L tau model. |
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Address |
[Sieber, H.; Crivelli, P.; Depero, E.; Bueno, L. Molina] Swiss Fed Inst Technol, Inst Particle Phys & Astrophys, CH-8093 Zurich, Switzerland, Email: laura.molina.bueno@cern.ch |
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Publisher |
Amer Physical Soc |
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English |
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ISSN |
2470-0010 |
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Conference |
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Notes |
WOS:000787220100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5207 |
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Author |
De La Torre Luque, P.; Gaggero, D.; Grasso, D.; Marinelli, A. |
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Title |
Prospects for detection of a galactic diffuse neutrino flux |
Type |
Journal Article |
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Year |
2022 |
Publication |
Frontiers in Astronomy and Space Sciences |
Abbreviated Journal |
Front. Astron. Space Sci. |
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Volume |
9 |
Issue |
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Pages |
1041838 - 9pp |
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Keywords |
galactic cosmic rays; cosmic-ray transport; diffuse gamma rays; high energy gamma rays; diffuse neutrinos; galactic plane |
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Abstract |
A Galactic cosmic-ray transport model featuring non-homogeneous transport has been developed over the latest years. This setup is aimed at reproducing gamma-ray observations in different regions of the Galaxy (with particular focus on the progressive hardening of the hadronic spectrum in the inner Galaxy) and was shown to be compatible with the very-high-energy gamma-ray diffuse emission recently detected up to PeV energies. In this work, we extend the results previously presented to test the reliability of that model throughout the whole sky. To this aim, we compare our predictions with detailed longitude and latitude profiles of the diffuse gamma-ray emission measured by Fermi-LAT for different energies and compute the expected Galactic nu diffuse emission, comparing it with current limits from the ANTARES collaboration. We emphasize that the possible detection of a Galactic nu component will allow us to break the degeneracy between our model and other scenarios featuring prominent contributions from unresolved sources and TeV halos. |
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Address |
[Luque, P. De La Torre] Stockholm Univ, Stockholm, Sweden, Email: pedro.delatorreluque@fysik.su.se; |
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Publisher |
Frontiers Media Sa |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2296-987x |
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Conference |
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Notes |
WOS:000884672800001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5407 |
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Author |
Real, D.; Calvo, D. |
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Title |
Production requirements and functional tests of the KM3NeT Digital Optical Module Power Board |
Type |
Journal Article |
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Year |
2022 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
1042 |
Issue |
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Pages |
167426 - 3pp |
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Keywords |
Power supply; Electronics reliability; Functional tests |
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Abstract |
The KM3NeT research facility is being built in the Mediterranean Sea. It consists of matrices of optical detectors, the so-called Digital Optical Module. Each of this elementary detector holds a set of 31 small-area photomultipliers, which detect the Cherenkov light generated by secondary particles produced in neutrino interactions. It includes also the acquisition electronics and the power board which supplies both, the acquisition electronics and the photomultipliers. The production of electronics boards needs to have a high quality and reliability level as it is going to be deployed for more than ten years without any maintenance possible. This work presents the requirements and the qualification tests being implemented in order to increase the reliability of the Power Board of the acquisition electronics of KM3NeT during the mass production. At the moment, more than one thousand board have been produced. Results on the production of the boards, including the production yield is presented. From the already produced boards, more than 350 have been already deployed and are operative in the detectors. |
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Address |
[Real, D.; Calvo, D.; KM3NeT Collaboration] Univ Valencia, IFIC Inst Fis Corpuscular, CSIC, C Catedrat Jose Beltran 2, Valencia 46980, Spain, Email: real@ific.uv.es |
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Thesis |
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Publisher |
Elsevier |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Conference |
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Notes |
WOS:000873950500001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5403 |
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Author |
Das, A.; Bhupal Dev, P.S.; Hosotani, Y.; Mandal, S. |
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Title |
Probing the minimal U(1)(X) model at future electron positron colliders via fermion pair-production channels |
Type |
Journal Article |
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Year |
2022 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
105 |
Issue |
11 |
Pages |
115030 - 28pp |
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Keywords |
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Abstract |
The minimal U(1)(X) extension of the Standard Model (SM) is a well-motivated new physics scenario, where anomaly cancellation dictates new neutral gauge boson (Z') couplings with the SM fermions in terms of the U(1)(X) charges of the new scalar fields. We investigate the SM charged fermion pair-production process for different values of these U(1)(X) charges at future e(-)e(+) colliders: e(+)e(-) -> f (f) over bar Apart from the standard gamma and Z-mediated processes, this model features additional s-channel (or both s and t-channel when f = e(-)) Z' exchange which interferes with the SM processes. We first estimate the bounds on the U(1)(X) coupling (g') and the Z' mass (M-Z') considering the latest dilepton and dijet constraints from the heavy resonance searches at the LHC. Then using the allowed values of g', we study the angular distributions, forward-backward (A(FB)), left-right (A(LB)), and left-right forward-backward (A(LR-FB)) asymmetries of the final states. We fmd that these observables can show substantial deviations from the SM results in the U(1)(X) model, thus providing a powerful probe of the multi-TeV Z' bosons at future e(+)e(-) colliders. |
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Address |
[Das, Arindam] Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea, Email: arindamdas@oia.hokudai.ac.jp; |
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Corporate Author |
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Thesis |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2470-0010 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000822972700011 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5283 |
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| Permanent link to this record |
