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Author Valdes-Cortez, C.; Niatsetski, Y.; Perez-Calatayud, J.; Ballester, F.; Vijande, J. doi  openurl
  Title (up) A Monte Carlo study of the relative biological effectiveness in surface brachytherapy Type Journal Article
  Year 2022 Publication Medical Physics Abbreviated Journal Med. Phys.  
  Volume 49 Issue Pages 5576-5588  
  Keywords Monte Carlo; relative biological effectiveness; surface HDR brachytherapy  
  Abstract Purpose This work aims to simulate clustered DNA damage from ionizing radiation and estimate the relative biological effectiveness (RBE) for radionuclide (rBT)- and electronic (eBT)-based surface brachytherapy through a hybrid Monte Carlo (MC) approach, using realistic models of the sources and applicators. Methods Damage from ionizing radiation has been studied using the Monte Carlo Damage Simulation algorithm using as input the primary electron fluence simulated using a state-of-the-art MC code, PENELOPE-2018. Two Ir-192 rBT applicators, Valencia and Leipzig, one Co-60 source with a Freiburg Flap applicator (reference source), and two eBT systems, Esteya and INTRABEAM, have been included in this study implementing full realizations of their geometries as disclosed by the manufacturer. The role played by filtration and tube kilovoltage has also been addressed. Results For rBT, an RBE value of about 1.01 has been found for the applicators and phantoms considered. In the case of eBT, RBE values for the Esteya system show an almost constant RBE value of about 1.06 for all depths and materials. For INTRABEAM, variations in the range of 1.12-1.06 are reported depending on phantom composition and depth. Modifications in the Esteya system, filtration, and tube kilovoltage give rise to variations in the same range. Conclusions Current clinical practice does not incorporate biological effects in surface brachytherapy. Therefore, the same absorbed dose is administered to the patients independently on the particularities of the rBT or eBT system considered. The almost constant RBE values reported for rBT support that assumption regardless of the details of the patient geometry, the presence of a flattening filter in the applicator design, or even significant modifications in the photon energy spectra above 300 keV. That is not the case for eBT, where a clear dependence on the eBT system and the characteristics of the patient geometry are reported. A complete study specific for each eBT system, including detailed applicator characteristics (size, shape, filtering, among others) and common anatomical locations, should be performed before adopting an existing RBE value.  
  Address [Valdes-Cortez, Christian] Hosp Reg Antofagasta, Nucl Med Dept, Antofagasta, Chile, Email: cvalcort@gmail.com  
  Corporate Author Thesis  
  Publisher Wiley Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0094-2405 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000811709400001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5262  
Permanent link to this record
 

 
Author Solevi, P. et al; Oliver, J.F.; Gillam, J.E.; Rafecas, M. doi  openurl
  Title (up) A Monte-Carlo based model of the AX-PET demonstrator and its experimental validation Type Journal Article
  Year 2013 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 58 Issue 16 Pages 5495-5510  
  Keywords  
  Abstract AX-PET is a novel PET detector based on axially oriented crystals and orthogonal wavelength shifter (WLS) strips, both individually read out by silicon photo-multipliers. Its design decouples sensitivity and spatial resolution, by reducing the parallax error due to the layered arrangement of the crystals. Additionally the granularity of AX-PET enhances the capability to track photons within the detector yielding a large fraction of inter-crystal scatter events. These events, if properly processed, can be included in the reconstruction stage further increasing the sensitivity. Its unique features require dedicated Monte-Carlo simulations, enabling the development of the device, interpreting data and allowing the development of reconstruction codes. At the same time the non-conventional design of AX-PET poses several challenges to the simulation and modeling tasks, mostly related to the light transport and distribution within the crystals and WLS strips, as well as the electronics readout. In this work we present a hybrid simulation tool based on an analytical model and a Monte-Carlo based description of the AX-PET demonstrator. It was extensively validated against experimental data, providing excellent agreement.  
  Address [Solevi, P.; Oliver, J. F.; Gillam, J. E.; Rafecas, M.] Univ Valencia, CSIC, IFIC, E-46071 Valencia, Spain, Email: paola.solevi@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000322775300012 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1544  
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Author Keivani, A.; Murase, K.; Petropoulou, M.; Fox, D.B.; Cenko, S.B.; Chaty, S.; Coleiro, A.; DeLaunay, J.J.; Dimitrakoudis, S.; Evans, P.A.; Kennea, J.A.; Marshall, F.E.; Mastichiadis, A.; Osborne, J.P.; Santander, M.; Tohuvavohu, A.; Turley, C.F. url  doi
openurl 
  Title (up) A Multimessenger Picture of the Flaring Blazar TXS 0506+056: Implications for High-energy Neutrino Emission and Cosmic-Ray Acceleration Type Journal Article
  Year 2018 Publication Astrophysical Journal Abbreviated Journal Astrophys. J.  
  Volume 864 Issue 1 Pages 84 - 16pp  
  Keywords Lacertae objects: general; BL Lacertae objects: individual (TXS 0506+056); galaxies: active; gamma rays: galaxies; neutrinos; radiation mechanisms: non-thermal  
  Abstract Detection of the IceCube-170922A neutrino coincident with the flaring blazar TXS 0506+056, the first and only similar to 3 sigma high-energy neutrino source association to date, offers a potential breakthrough in our understanding of high-energy cosmic particles and blazar physics. We present a comprehensive analysis of TXS. 0506+056 during its flaring state, using newly collected Swift, NuSTAR, and X-shooter data with Fermi observations and numerical models to constrain the blazar's particle acceleration processes and multimessenger (electromagnetic (EM) and high-energy neutrino) emissions. Accounting properly for EM cascades in the emission region, we find a physically consistent picture only within a hybrid leptonic scenario, with gamma-rays produced by external inverse-Compton processes and high-energy neutrinos via a radiatively subdominant hadronic component. We derive robust constraints on the blazar's neutrino and cosmic-ray emissions and demonstrate that, because of cascade effects, the 0.1-100 keV emissions of TXS. 0506+056 serve as a better probe of its hadronic acceleration and highenergy neutrino production processes than its GeV-TeV emissions. If the IceCube neutrino association holds, physical conditions in the TXS. 0506+056 jet must be close to optimal for high-energy neutrino production, and are not favorable for ultrahigh-energy cosmic-ray acceleration. Alternatively, the challenges we identify in generating a significant rate of IceCube neutrino detections from TXS. 0506+056 may disfavor single-zone models, in which.-rays and high-energy neutrinos are produced in a single emission region. In concert with continued operations of the high-energy neutrino observatories, we advocate regular X-ray monitoring of TXS. 0506+056 and other blazars in order to test single-zone blazar emission models, clarify the nature and extent of their hadronic acceleration processes, and carry out the most sensitive possible search for additional multimessenger sources.  
  Address [Keivani, A.; Murase, K.; DeLaunay, J. J.; Turley, C. F.] Penn State Univ, Dept Phys, 104 Davey Lab, University Pk, PA 16802 USA, Email: keivani@psu.edu;  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0004-637x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000443293800010 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 3708  
Permanent link to this record
 

 
Author Real, D.; Calvo, D.; Diaz, A.; Salesa Greus, F.; Sanchez Losa, A. doi  openurl
  Title (up) A Narrow Optical Pulse Emitter Based on LED: NOPELED Type Journal Article
  Year 2022 Publication Sensors Abbreviated Journal Sensors  
  Volume 22 Issue 19 Pages 7683 - 15pp  
  Keywords short optical pulse; optical instrumentation  
  Abstract Light sources emitting short pulses are needed in many particle physics experiments using optical sensors as they can replicate the light produced by the particles being detected and are also an important calibration and test element. This work presents NOPELED, a light source based on LEDs emitting short optical pulses with typical rise times of less than 3 ns and Full Width at Half Maximum lower than 7 ns. The emission wavelength depends on the model of LED used. Several LED models have been characterized in the range from 405 to 532 nm, although NOPELED can work with LED emitting wavelengths outside of that region. While the wavelength is fixed for a given LED model, the intensity and the frequency of the optical pulse can be controlled. NOPELED, which also has low cost and simple operation, can be operated remotely, making it appropriate for either different physics experiments needing in-place light sources such as astrophysical neutrino detectors using photo-multipliers or positron emission tomography devices using scintillation counters, or, beyond physics, applications needing short pulses of light such as protein fluorescence or chemodetection of heavy metals.  
  Address [Real, Diego; Calvo, David; Salesa Greus, Francisco; Sanchez Losa, Agustin] Univ Valencia, IFIC Inst Fis Corpuscular, CSIC, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: real@ific.uv.es;  
  Corporate Author Thesis  
  Publisher Mdpi Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000867935300001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5381  
Permanent link to this record
 

 
Author Dote, A.; Bayar, M.; Xiao, C.W.; Hyodo, T.; Oka, M.; Oset, E. doi  openurl
  Title (up) A narrow quasi-bound state of the DNN system Type Journal Article
  Year 2013 Publication Nuclear Physics A Abbreviated Journal Nucl. Phys. A  
  Volume 914 Issue Pages 499-504  
  Keywords Nuclear system with a D meson; Few-body system; Variational calculation; Faddeev calculation  
  Abstract We have investigated a charmed system of DNN (composed of two nucleons and a D meson) by a complementary study with a variational calculation and a Faddeev calculation with fixed-center approximation (Faddeev-FCA). In the present study, we employ a DN potential based on a vector-meson exchange picture in which a resonant A(c)(2595) is dynamically generated as a DN quasi-bound state, similarly to the A(1405) as a (K) over barN one in the strange sector. As a result of the study of variational calculation with an effective DN potential and three kinds of NN potentials, the DNN(J(pi) =0(-), I = 1/2) is found to be a narrow quasi-bound state below A(c)(2595)N threshold: total binding energy similar to 225 MeV and mesonic decay width similar to 25 MeV. On the other hand, the J(pi) =1(-) state is considered to be a scattering state of A(c)(2595) and a nucleon. These results are essentially supported by the Faddeev-FCA calculation. By the analysis of the variational wave function, we have found a unique structure in the DNN(J(pi) = 0, I = 1/2) such that the D meson stays around the center of the total system due to the heaviness of the D meson.  
  Address [Dote, A.] High Energy Accelerator Res Org KEK, IPNS, KEK Theory Ctr, Tsukuba, Ibaraki 3050801, Japan, Email: dote@post.kek.jp  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0375-9474 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000324847700071 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1602  
Permanent link to this record
 

 
Author ATLAS Collaboration (Aad, G. et al); Cabrera Urban, S.; Castillo Gimenez, V.; Costa, M.J.; Ferrer, A.; Fiorini, L.; Fuster, J.; Garcia, C.; Garcia Navarro, J.E.; Gonzalez de la Hoz, S.; Hernandez Jimenez, Y.; Higon-Rodriguez, E.; Irles Quiles, A.; Kaci, M.; King, M.; Lacasta, C.; Lacuesta, V.R.; March, L.; Marti-Garcia, S.; Mitsou, V.A.; Moles-Valls, R.; Oliver Garcia, E.; Pedraza Lopez, S.; Perez Garcia-Estañ, M.T.; Romero Adam, E.; Ros, E.; Salt, J.; Sanchez Martinez, V.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valero, A.; Valladolid Gallego, E.; Valls Ferrer, J.A.; Vos, M. url  doi
openurl 
  Title (up) A neural network clustering algorithm for the ATLAS silicon pixel detector Type Journal Article
  Year 2014 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.  
  Volume 9 Issue Pages P09009 - 34pp  
  Keywords Particle tracking detectors; Particle tracking detectors (Solid-state detectors)  
  Abstract A novel technique to identify and split clusters created by multiple charged particles in the ATLAS pixel detector using a set of artificial neural networks is presented. Such merged clusters are a common feature of tracks originating from highly energetic objects, such as jets. Neural networks are trained using Monte Carlo samples produced with a detailed detector simulation. This technique replaces the former clustering approach based on a connected component analysis and charge interpolation. The performance of the neural network splitting technique is quantified using data from proton-proton collisions at the LHC collected by the ATLAS detector in 2011 and from Monte Carlo simulations. This technique reduces the number of clusters shared between tracks in highly energetic jets by up to a factor of three. It also provides more precise position and error estimates of the clusters in both the transverse and longitudinal impact parameter resolution.  
  Address [Jackson, P.; Soni, N.; White, M. J.] Univ Adelaide, Dept Phys, Adelaide, SA, Australia  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1748-0221 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000343281300046 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1972  
Permanent link to this record
 

 
Author Stuhl, L.; Krasznahorkay, A.; Csatlos, M.; Algora, A.; Gulyas, J.; Kalinka, G.; Timar, J.; Kalantar-Nayestanaki, N.; Rigollet, C.; Bagchi, S.; Najafi, M.A. url  doi
openurl 
  Title (up) A neutron spectrometer for studying giant resonances with (p,n) reactions in inverse kinematics Type Journal Article
  Year 2014 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A  
  Volume 736 Issue Pages 1-9  
  Keywords Low-energy neutron spectrometer; Neutron time-of-flight measurements; ELENS; VM2000 wrapping  
  Abstract A neutron spectrometer, the European Low-Energy Neutron Spectrometer (ELENS), has been constructed to study exotic nuclei in inverse-kinematics experiments. The spectrometer, which consists of plastic scintillator bars, can be operated in the neutron energy range of 100 keV-10 MeV. The neutron energy is determined using the time-of-flight technique, while the position of the neutron detection is deduced from the time-difference information from photomultipliers attached to both ends of each bar. A novel wrapping method has been developed for the plastic scintillators. The array has a larger than 25% detection efficiency for neutrons of approximately 500 keV in kinetic energy and an angular resolution of less than 1 degrees. Details of the design, construction and experimental tests of the spectrometer will be presented.  
  Address [Stuhl, L.; Krasznahorkay, A.; Csatlos, M.; Algora, A.; Gulyas, J.; Kalinka, G.; Timar, J.] Hungarian Acad Sci, Inst Nucl Res, ATOMKI, Debrecen, Hungary, Email: stuhl@atomki.hu  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0168-9002 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000329404000002 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1695  
Permanent link to this record
 

 
Author LHCb Collaboration (Aaij, R. et al); Martinez-Vidal, F.; Oyanguren, A.; Ruiz Valls, P.; Sanchez Mayordomo, C. url  doi
openurl 
  Title (up) A new algorithm for identifying the flavour of B-s(0) mesons at LHCb Type Journal Article
  Year 2016 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.  
  Volume 11 Issue Pages P05010 - 23pp  
  Keywords Analysis and statistical methods; Particle identification methods; Pattern recognition; cluster finding; calibration and fitting methods  
  Abstract A new algorithm for the determination of the initial flavour of B-s(0) mesons is presented. The algorithm is based on two neural networks and exploits the b hadron production mechanism at a hadron collider. The first network is trained to select charged kaons produced in association with the B-s(0) meson. The second network combines the kaon charges to assign the B-s(0) flavour and estimates the probability of a wrong assignment. The algorithm is calibrated using data corresponding to an integrated luminosity of 3 fb(-1) collected by the LHCb experiment in proton-proton collisions at 7 and 8 TeV centre-of-mass energies. The calibration is performed in two ways: by resolving the B-s(0)-B-s(0) flavour oscillations in B-s(0) -> D-s(-)pi(+) decays, and by analysing flavour-specific B-s2*(5840)(0) -> B+K- decays. The tagging power measured in B-s(0) -> D-s(-)pi(+) decays is found to be (1.80 +/- 0.19 ( stat) +/- 0.18 (syst))%, which is an improvement of about 50% compared to a similar algorithm previously used in the LHCb experiment.  
  Address [Bediaga, I.; De Miranda, J. M.; Rodrigues, F. Ferreira; Gomes, A.; Massafferri, A.; Rodrigues, B. Osorio; dos Reis, A. C.; Rodrigues, A. B.] CBPF, Rio De Janeiro, Brazil, Email: mirco.dorigo@cern.ch  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1748-0221 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000377851700033 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2731  
Permanent link to this record
 

 
Author Hernandez, P.; Pena, C.; Ramos, A.; Gomez-Cadenas, J.J. url  doi
openurl 
  Title (up) A new formulation of compartmental epidemic modelling for arbitrary distributions of incubation and removal times Type Journal Article
  Year 2021 Publication Plos One Abbreviated Journal PLoS One  
  Volume 16 Issue 2 Pages e0244107 - 22pp  
  Keywords  
  Abstract The paradigm for compartment models in epidemiology assumes exponentially distributed incubation and removal times, which is not realistic in actual populations. Commonly used variations with multiple exponentially distributed variables are more flexible, yet do not allow for arbitrary distributions. We present a new formulation, focussing on the SEIR concept that allows to include general distributions of incubation and removal times. We compare the solution to two types of agent-based model simulations, a spatially homogeneous one where infection occurs by proximity, and a model on a scale-free network with varying clustering properties, where the infection between any two agents occurs via their link if it exists. We find good agreement in both cases. Furthermore a family of asymptotic solutions of the equations is found in terms of a logistic curve, which after a non-universal time shift, fits extremely well all the microdynamical simulations. The formulation allows for a simple numerical approach; software in Julia and Python is provided.  
  Address [Hernandez, Pilar] Univ Valencia, Dept Fis Teor, Valencia, Spain, Email: m.pilar.hernandez@uv.es  
  Corporate Author Thesis  
  Publisher Public Library Science Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1932-6203 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000616739700053 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 4750  
Permanent link to this record
 

 
Author Egea Canet, F.J. et al; Gadea, A.; Huyuk, T. doi  openurl
  Title (up) A New Front-End High-Resolution Sampling Board for the New-Generation Electronics of EXOGAM2 and NEDA Detectors Type Journal Article
  Year 2015 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.  
  Volume 62 Issue 3 Pages 1056-1062  
  Keywords Acquisition in HP-Ge detectors; high-speed ADCs; low-noise electronics design  
  Abstract This paper presents the final design and results of the FADC Mezzanine for the EXOGAM (EXOtic GAMma array spectrometer) and NEDA (Neutron Detector Array) detectors. The measurements performed include those of studying the effective number of bits, the energy resolution using HP-Ge detectors, as well as timing histograms and discrimination performance. Finally, the conclusion shows how a common digitizing device has been integrated in the experimental environment of two very different detectors which combine both low-noise acquisition and fast sampling rates. Not only the integration fulfilled the expected specifications on both systems, but it also showed how a study of synergy between detectors could lead to the reduction of resources and time by applying a common strategy.  
  Address [Egea Canet, F. J.; Gonzalez, V.; Sanchis, E.] Univ Valencia, Dept Elect Engn, Escola Tecn Super Engn, Valencia, Spain, Email: jaegea@ific.uv.es  
  Corporate Author Thesis  
  Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0018-9499 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000356458000028 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2278  
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