Oliver-Canamas, L., Vijande, J., Candela-Juan, C., Gimeno-Olmos, J., Pujades-Claumarchirant, M. C., Rovira-Escutia, J. J., et al. (2023). A User-Friendly System for Mailed Dosimetric Audits of Ir-192 or Co-60 HDR Brachytherapy Sources. Cancers, 15(9), 2484–14pp.
Abstract: Nowadays, the options available to perform external dosimetric audits of the high dose rate (HDR) brachytherapy treatment process are limited. In this work, we present a methodology that allows for performing dosimetric audits in this field. A phantom was designed and manufactured for this purpose. The criteria for its design, together with the in-house measurements for its characterization, are presented. The result is a user-friendly system that can be mailed to perform dosimetric audits in HDR brachytherapy on-site for systems using either Iridium-192 (Ir-192) or Cobalt-60 (Co-60) sources. Objectives: The main goal of this work is to design and characterize a user-friendly methodology to perform mailed dosimetric audits in high dose rate (HDR) brachytherapy for systems using either Iridium-192 (Ir-192) or Cobalt-60 (Co-60) sources. Methods: A solid phantom was designed and manufactured with four catheters and a central slot to place one dosimeter. Irradiations with an Elekta MicroSelectron V2 for Ir-192, and with a BEBIG Multisource for Co-60 were performed for its characterization. For the dose measurements, nanoDots, a type of optically stimulated luminescent dosimeters (OSLDs), were characterized. Monte Carlo (MC) simulations were performed to evaluate the scatter conditions of the irradiation set-up and to study differences in the photon spectra of different Ir-192 sources (Microselectron V2, Flexisource, BEBIG Ir2.A85-2 and Varisource VS2000) reaching the dosimeter in the irradiation set-up. Results: MC simulations indicate that the surface material on which the phantom is supported during the irradiations does not affect the absorbed dose in the nanoDot. Generally, differences below 5% were found in the photon spectra reaching the detector when comparing the Microselectron V2, the Flexisource and the BEBIG models. However, differences up to 20% are observed between the V2 and the Varisource VS2000 models. The calibration coefficients and the uncertainty in the dose measurement were evaluated. Conclusions: The system described here is able to perform dosimetric audits in HDR brachytherapy for systems using either Ir-192 or Co-60 sources. No significant differences are observed between the photon spectra reaching the detector for the MicroSelectron V2, the Flexisource and the BEBIG Ir-192 sources. For the Varisource VS2000, a higher uncertainty is considered in the dose measurement to allow for the nanoDot response.
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Bordes, J., Chan, H. M., & Tsou, S. T. (2023). A vacuum transition in the FSM with a possible new take on the horizon problem in cosmology. Int. J. Mod. Phys. A, 38(25), 2350124–32pp.
Abstract: The framed standard model (FSM), constructed to explain the empirical mass and mixing patterns (including CP phases) of quarks and leptons, in which it has done quite well, gives otherwise the same result as the standard model (SM) in almost all areas in particle physics where the SM has been successfully applied, except for a few specified deviations such as the W mass and the g-2 of muons, that is, just where experiment is showing departures from what SM predicts. It predicts further the existence of a hidden sector of particles some of which may function as dark matter. In this paper, we first note that the above results involve, surprisingly, the FSM undergoing a vacuum transition (VTR1) at a scale of around 17MeV, where the vacuum expectation values of the colour framons (framed vectors promoted into fields) which are all nonzero above that scale acquire some vanishing components below it. This implies that the metric pertaining to these vanishing components would vanish also. Important consequences should then ensue, but these occur mostly in the unknown hidden sector where empirical confirmation is hard at present to come by, but they give small reflections in the standard sector, some of which may have already been seen. However, one notes that if, going off at a tangent, one imagines colour to be embedded, Kaluza-Klein (KK) fashion, into a higher-dimensional space-time, then this VTR1 would cause 2 of the compactified dimensions to collapse. This might mean then that when the universe cooled to the corresponding temperature of 1011 K when it was about 10-3 s old, this VTR1 collapse would cause the three spatial dimensions of the universe to expand to compensate. The resultant expansion is estimated, using FSM parameters previously determined from particle physics, to be capable, when extrapolated backwards in time, of bringing the present universe back inside the then horizon, solving thus formally the horizon problem. Besides, VTR1 being a global phenomenon in the FSM, it would switch on and off automatically and simultaneously over all space, thus requiring seemingly no additional strategy for a graceful exit. However, this scenario has not been checked for consistency with other properties of the universe and is to be taken thus not as a candidate solution of the horizon problem but only as an observation from particle physics which might be of interest to cosmologists and experts in the early universe. For particle physicists also, it might serve as an indicator for how relevant this VTR1 can be, even if the KK assumption is not made.
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Breso-Pla, V., Falkowski, A., & Gonzalez-Alonso, M. (2021). A(FB) in the SMEFT: precision Z physics at the LHC. J. High Energy Phys., 08(8), 021–27pp.
Abstract: We study the forward-backward asymmetry A(FB) in pp -> l(+)l(-) at the Z peak within the Standard Model Effective Field Theory (SMEFT). We find that this observable provides per mille level constraints on the vertex corrections of the Z boson to quarks, which close a flat direction in the electroweak precision SMEFT fit. Moreover, we show that current A(FB) data is precise enough so that its inclusion in the fit improves significantly LEP bounds even in simple New Physics setups. This demonstrates that the LHC can compete with and complement LEP when it comes to precision measurements of the Z boson properties.
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Beaulieu, L., Ballester, F., Granero, D., Tedgren, A. C., Haworth, A., Lowenstein, J. R., et al. (2023). AAPM WGDCAB Report 372: A joint AAPM, ESTRO, ABG, and ABS report on commissioning of model-based dose calculation algorithms in brachytherapy. Med. Phys., 50(8), e946–e960.
Abstract: The introduction of model-based dose calculation algorithms (MBDCAs) in brachytherapy provides an opportunity for a more accurate dose calculation and opens the possibility for novel, innovative treatment modalities. The joint AAPM, ESTRO, and ABG Task Group 186 (TG-186) report provided guidance to early adopters. However, the commissioning aspect of these algorithms was described only in general terms with no quantitative goals. This report, from the Working Group on Model-Based Dose Calculation Algorithms in Brachytherapy, introduced a field-tested approach to MBDCA commissioning. It is based on a set of well-characterized test cases for which reference Monte Carlo (MC) and vendor-specific MBDCA dose distributions are available in a Digital Imaging and Communications in Medicine-Radiotherapy (DICOM-RT) format to the clinical users. The key elements of the TG-186 commissioning workflow are now described in detail, and quantitative goals are provided. This approach leverages the well-known Brachytherapy Source Registry jointly managed by the AAPM and the Imaging and Radiation Oncology Core (IROC) Houston Quality Assurance Center (with associated links at ESTRO) to provide open access to test cases as well as step-by-step user guides. While the current report is limited to the two most widely commercially available MBDCAs and only for Ir-192-based afterloading brachytherapy at this time, this report establishes a general framework that can easily be extended to other brachytherapy MBDCAs and brachytherapy sources. The AAPM, ESTRO, ABG, and ABS recommend that clinical medical physicists implement the workflow presented in this report to validate both the basic and the advanced dose calculation features of their commercial MBDCAs. Recommendations are also given to vendors to integrate advanced analysis tools into their brachytherapy treatment planning system to facilitate extensive dose comparisons. The use of the test cases for research and educational purposes is further encouraged.
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Segarra, A., & Bernabeu, J. (2020). Absolute neutrino mass and the Dirac/Majorana distinction from the weak interaction of aggregate matter. Phys. Rev. D, 101(9), 093004–6pp.
Abstract: The 2 nu-mediated force has a range of microns, well beyond the atomic scale. The effective potential is built from the t-channel absorptive part of the scattering amplitude and depends on neutrino properties on shell. We demonstrate that neutral aggregate matter has a weak charge and calculate the matrix of six coherent charges for its interaction with definite-mass neutrinos. Near the range of the potential the neutrino pair is nonrelativistic, leading to observable absolute mass and Dirac/Majorana distinction via different r-dependence and violation of the weak equivalence principle.
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Centelles Chulia, S., Cepedello, R., & Medina, O. (2022). Absolute neutrino mass scale and dark matter stability from flavour symmetry. J. High Energy Phys., 10(10), 080–23pp.
Abstract: We explore a simple but extremely predictive extension of the scotogenic model. We promote the scotogenic symmetry Z(2) to the flavour non-Abelian symmetry sigma(81), which can also automatically protect dark matter stability. In addition, sigma(81) leads to striking predictions in the lepton sector: only Inverted Ordering is realised, the absolute neutrino mass scale is predicted to be m(lightest)approximate to 7.5x10(-4) eV and the Majorana phases are correlated in such a way that vertical bar m(ee)vertical bar approximate to 0.018 eV. The model also leads to a strong correlation between the solar mixing angle theta(12) and delta(CP), which may be falsified by the next generation of neutrino oscillation experiments. The setup is minimal in the sense that no additional symmetries or flavons are required.
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Pompa, F., Capozzi, F., Mena, O., & Sorel, M. (2022). Absolute nu Mass Measurement with the DUNE Experiment. Phys. Rev. Lett., 129(12), 121802–6pp.
Abstract: Time of flight delay in the supernova neutrino signal offers a unique tool to set model-independent constraints on the absolute neutrino mass. The presence of a sharp time structure during a first emission phase, the so-called neutronization burst in the electron neutrino flavor time distribution, makes this channel a very powerful one. Large liquid argon underground detectors will provide precision measurements of the time dependence of the electron neutrino fluxes. We derive here a new v mass sensitivity attainable at the future DUNE far detector from a future supernova collapse in our galactic neighborhood, finding a sub-eV reach under favorable scenarios. These values are competitive with those expected for laboratory direct neutrino mass searches.
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Delhom, A., Macedo, C. F. B., Olmo, G. J., & Crispino, L. C. B. (2019). Absorption by black hole remnants in metric-affine gravity. Phys. Rev. D, 100(2), 024016–12pp.
Abstract: Using numerical methods, we investigate the absorption properties of a family of nonsingular solutions which arise in different metric-affine theories, such as quadratic and Born-Infeld gravity. These solutions continuously interpolate between Schwarzschild black holes and naked solitons with wormhole topology. The resulting spectrum is characterized by a series of quasibound states excitations, associated with the existence of a stable photonsphere.
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Olmo, G. J., Rubiera-Garcia, D., & Sanchez-Puente, A. (2018). Accelerated observers and the notion of singular spacetime. Class. Quantum Gravity, 35(5), 055010–18pp.
Abstract: Geodesic completeness is typically regarded as a basic criterion to determine whether a given spacetime is regular or singular. However, the principle of general covariance does not privilege any family of observers over the others and, therefore, observers with arbitrary motions should be able to provide a complete physical description of the world. This suggests that in a regular spacetime, all physically acceptable observers should have complete paths. In this work we explore this idea by studying the motion of accelerated observers in spherically symmetric spacetimes and illustrate it by considering two geodesically complete black hole spacetimes recently described in the literature. We show that for bound and locally unbound accelerations, the paths of accelerated test particles are complete, providing further support to the regularity of such spacetimes.
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Begone, G., Deisenroth, M. P., Kim, J. S., Liem, S., Ruiz de Austri, R., & Welling, M. (2019). Accelerating the BSM interpretation of LHC data with machine learning. Phys. Dark Universe, 24, 100293–5pp.
Abstract: The interpretation of Large Hadron Collider (LHC) data in the framework of Beyond the Standard Model (BSM) theories is hampered by the need to run computationally expensive event generators and detector simulators. Performing statistically convergent scans of high-dimensional BSM theories is consequently challenging, and in practice unfeasible for very high-dimensional BSM theories. We present here a new machine learning method that accelerates the interpretation of LHC data, by learning the relationship between BSM theory parameters and data. As a proof-of-concept, we demonstrate that this technique accurately predicts natural SUSY signal events in two signal regions at the High Luminosity LHC, up to four orders of magnitude faster than standard techniques. The new approach makes it possible to rapidly and accurately reconstruct the theory parameters of complex BSM theories, should an excess in the data be discovered at the LHC.
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