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Ballester, F.; Tedgren, A.C.; Granero, D.; Haworth, A.; Mourtada, F.; Fonseca, G.P.; Zourari, K.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.L.; Thomson, R.M.; Verhaegen, F.; Vijande, J.; Ma, Y.Z.; Beaulieu, L. |
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Title  |
A generic high-dose rate Ir-192 brachytherapy source for evaluation of model-based dose calculations beyond the TG-43 formalism |
Type |
Journal Article |
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Year |
2015 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
42 |
Issue |
6 |
Pages |
3048-3062 |
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Keywords |
Ir-192; HDR brachytherapy; Monte Carlo methods; model-based dose calculation; TG-186 |
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Abstract |
Purpose: In order to facilitate a smooth transition for brachytherapy dose calculations from the American Association of Physicists in Medicine (AAPM) Task Group No. 43 (TG-43) formalism to model-based dose calculation algorithms (MBDCAs), treatment planning systems (TPSs) using a MBDCA require a set of well-defined test case plans characterized by Monte Carlo (MC) methods. This also permits direct dose comparison to TG-43 reference data. Such test case plans should be made available for use in the software commissioning process performed by clinical end users. To this end, a hypothetical, generic high-dose rate (HDR) Ir-192 source and a virtual water phantom were designed, which can be imported into a TPS. Methods: A hypothetical, generic HDR Ir-192 source was designed based on commercially available sources as well as a virtual, cubic water phantom that can be imported into any TPS in DICOM format. The dose distribution of the generic Ir-192 source when placed at the center of the cubic phantom, and away from the center under altered scatter conditions, was evaluated using two commercial MBDCAs [Oncentra (R) Brachy with advanced collapsed-cone engine (ACE) and BrachyVision AcuRos (TM)]. Dose comparisons were performed using state-of-the-art MC codes for radiation transport, including ALGEBRA, BrachyDose, GEANT4, MCNP5, MCNP6, and pENELopE2008. The methodologies adhered to recommendations in the AAPM TG-229 report on high-energy brachytherapy source dosimetry. TG-43 dosimetry parameters, an along-away dose-rate table, and primary and scatter separated (PSS) data were obtained. The virtual water phantom of (201)(3) voxels (1 mm sides) was used to evaluate the calculated dose distributions. Two test case plans involving a single position of the generic HDR Ir-192 source in this phantom were prepared: (i) source centered in the phantom and (ii) source displaced 7 cm laterally from the center. Datasets were independently produced by different investigators. MC results were then compared against dose calculated using TG-43 and MBDCA methods. Results: TG-43 and PSS datasets were generated for the generic source, the PSS data for use with the ACE algorithm. The dose-rate constant values obtained from seven MC simulations, performed independently using different codes, were in excellent agreement, yielding an average of 1.1109 +/- 0.0004 cGy/(h U) (k = 1, Type A uncertainty). MC calculated dose-rate distributions for the two plans were also found to be in excellent agreement, with differences within type A uncertainties. Differences between commercial MBDCA and MC results were test, position, and calculation parameter dependent. On average, however, these differences were within 1% for ACUROS and 2% for ACE at clinically relevant distances. Conclusions: A hypothetical, generic HDR Ir-192 source was designed and implemented in two commercially available TPSs employing different MBDCAs. Reference dose distributions for this source were benchmarked and used for the evaluation of MBDCA calculations employing a virtual, cubic water phantom in the form of a CT DICOM image series. The implementation of a generic source of identical design in all TPSs using MBDCAs is an important step toward supporting univocal commissioning procedures and direct comparisons between TPSs. |
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Address |
[Ballester, Facundo] Univ Valencia, Dept Atom Mol & Nucl Phys, E-46100 Burjassot, Spain, Email: Facundo.Ballester@uv.es |
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Amer Assoc Physicists Medicine Amer Inst Physics |
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English |
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ISSN |
0094-2405 |
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Conference |
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Notes |
WOS:000356998300031 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2315 |
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Author |
Ma, Y.Z.; Vijande, J.; Ballester, F.; Tedgren, A.C.; Granero, D.; Haworth, A.; Mourtada, F.; Fonseca, G.P.; Zourari, K.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.; Chamberland, M.J.P.; Thomson, R.M.; Verhaegen, F.; Beaulieu, L. |
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Title |
A generic TG-186 shielded applicator for commissioning model-based dose calculation algorithms for high-dose-rate Ir-192 brachytherapy |
Type |
Journal Article |
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Year |
2017 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
44 |
Issue |
11 |
Pages |
5961-5976 |
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Keywords |
Ir-192; HDR brachytherapy; model based dose calculation; Monte Carlo methods; shielded applicator; TG-186 |
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Abstract |
PurposeA joint working group was created by the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) with the charge, among others, to develop a set of well-defined test case plans and perform calculations and comparisons with model-based dose calculation algorithms (MBDCAs). Its main goal is to facilitate a smooth transition from the AAPM Task Group No. 43 (TG-43) dose calculation formalism, widely being used in clinical practice for brachytherapy, to the one proposed by Task Group No. 186 (TG-186) for MBDCAs. To do so, in this work a hypothetical, generic high-dose rate (HDR) Ir-192 shielded applicator has been designed and benchmarked. MethodsA generic HDR Ir-192 shielded applicator was designed based on three commercially available gynecological applicators as well as a virtual cubic water phantom that can be imported into any DICOM-RT compatible treatment planning system (TPS). The absorbed dose distribution around the applicator with the TG-186 Ir-192 source located at one dwell position at its center was computed using two commercial TPSs incorporating MBDCAs (Oncentra((R)) Brachy with Advanced Collapsed-cone Engine, ACE, and BrachyVision ACUROS) and state-of-the-art Monte Carlo (MC) codes, including ALGEBRA, BrachyDose, egs_brachy, Geant4, MCNP6, and Penelope2008. TPS-based volumetric dose distributions for the previously reported source centered in water and source displaced test cases, and the new source centered in applicator test case, were analyzed here using the MCNP6 dose distribution as a reference. Volumetric dose comparisons of TPS results against results for the other MC codes were also performed. Distributions of local and global dose difference ratios are reported. ResultsThe local dose differences among MC codes are comparable to the statistical uncertainties of the reference datasets for the source centered in water and source displaced test cases and for the clinically relevant part of the unshielded volume in the source centered in applicator case. Larger local differences appear in the shielded volume or at large distances. Considering clinically relevant regions, global dose differences are smaller than the local ones. The most disadvantageous case for the MBDCAs is the one including the shielded applicator. In this case, ACUROS agrees with MC within [-4.2%, +4.2%] for the majority of voxels (95%) while presenting dose differences within [-0.12%, +0.12%] of the dose at a clinically relevant reference point. For ACE, 95% of the total volume presents differences with respect to MC in the range [-1.7%, +0.4%] of the dose at the reference point. ConclusionsThe combination of the generic source and generic shielded applicator, together with the previously developed test cases and reference datasets (available in the Brachytherapy Source Registry), lay a solid foundation in supporting uniform commissioning procedures and direct comparisons among treatment planning systems for HDR Ir-192 brachytherapy. |
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[Ma, Yunzhi; Beaulieu, Luc] CHU Quebec, Dept Radio Oncol & Axe Oncol, Ctr Rech, Quebec City, PQ G1R 2J6, Canada, Email: yunzhi.Ma@crchuq.ulaval.ca |
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Wiley |
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English |
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0094-2405 |
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Notes |
WOS:000414970800039 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3370 |
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Author |
Feijoo, A.; Magas, V.K.; Ramos, A.; Oset, E. |
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Title |
A hidden-charm S =-1 pentaquark from the decay Lambda(b) into J/psi eta Lambda states |
Type |
Journal Article |
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Year |
2016 |
Publication |
European Physical Journal C |
Abbreviated Journal |
Eur. Phys. J. C |
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Volume |
76 |
Issue |
8 |
Pages |
446 - 12pp |
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Abstract |
The hidden-charm pentaquark P-c(4450) observed recently by the LHCb collaboration may be of molecular nature, as advocated by some unitary approaches that also predict pentaquark partners in the strangeness S = -1 sector. In this work we argue that a hidden-charm strange pentaquark could be seen from the decay of the Lambda b, just as in the case of the non-strange P-c(4450), but looking into the J/psi eta Lambda decay mode and forming the invariant mass spectrum of J/psi Lambda pairs. In the model presented here, which assumes a standard weak decay topology and incorporates the hadronization process and final-state interaction effects, we find the J/psi eta Lambda final states to be populated with similar strength as the J/psi K- p states employed for the observation of the non-strange pentaquark. This makes the Lambda b -> J/psi eta Lambda decay to be an interesting process to observe a possible strange partner of the P-c(4450). We study the dependence of the J/psi Lambda mass spectra on various model ingredients and on the unknown properties of the strange pentaquark. |
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Address |
[Feijoo, A.; Magas, V. K.; Ramos, A.] Univ Barcelona, Dept Fis Quant & Astrofis, Inst Ciencies Cosmos ICCUB, Marti & Franques 1, E-08028 Barcelona, Spain, Email: feijoo@icc.ub.edu; |
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Springer |
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English |
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1434-6044 |
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Notes |
WOS:000399606600001 |
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no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
3058 |
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Author |
Baeza-Ballesteros, J.; Hernandez, P.; Romero-Lopez, F. |
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Title |
A lattice study of pi pi scattering at large N-c |
Type |
Journal Article |
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Year |
2022 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
06 |
Issue |
6 |
Pages |
049 - 39pp |
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Keywords |
Hadronic Spectroscopy; Structure and Interactions; Lattice QCD; 1/N Expansion; Chiral Lagrangian |
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Abstract |
We present the first lattice study of pion-pion scattering with varying number of colors, N-c. We use lattice simulations with four degenerate quark flavors, N-f = 4, and N-c= 3 – 6. We focus on two scattering channels that do not involve vacuum diagrams. These correspond to two irreducible representations of the SU(4) flavor group: the fully symmetric one, SS, and the fully antisymmetric one, AA. The former is a repulsive channel equivalent to the isospin-2 channel of SU(2). By contrast, the latter is attractive and only exists for N-f >= 4. A representative state is (vertical bar D-s(+) pi(+)> – vertical bar D+ K+ >) /root 2. Using Lfischer's formalism, we extract the near-threshold scattering amplitude and we match our results to Chiral Perturbation Theory (ChPT) at large N-c. For this, we compute the analytical U(N-f) ChPT prediction for two-pion scattering, and use the lattice results to constrain the N-c scaling of the relevant low-energy couplings. |
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[Baeza-Ballesteros, Jorge; Hernandez, Pilar; Romero-Lopez, Fernando] Univ Valencia, CSIC, IFIC, Paterna 46980, Spain, Email: jorge.baeza@uv.es; |
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Springer |
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English |
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ISSN |
1029-8479 |
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Notes |
WOS:000809342900001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5258 |
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Author |
ATLAS Collaboration (Abat, E. et al); Bernabeu Verdú, J.; Castillo Gimenez, V.; Costa, M.J.; Escobar, C.; Ferrer, A.; Garcia, C.; Gonzalez-Sevilla, S.; Higon-Rodriguez, E.; Lacasta, C.; Marti-Garcia, S.; Mitsou, V.A.; Ruiz, A.; Solans, C.; Valero, A.; Valls Ferrer, J.A. |
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Title |
A layer correlation technique for pion energy calibration at the 2004 ATLAS Combined Beam Test |
Type |
Journal Article |
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Year |
2011 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
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Volume |
6 |
Issue |
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Pages |
P06001 - 35pp |
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Keywords |
Calorimeter methods; Pattern recognition, cluster finding, calibration and fitting methods; Calorimeters; Detector modelling and simulations I (interaction of radiation with matter, interaction of photons with matter, interaction of hadrons with matter, etc) |
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Abstract |
A new method for calibrating the hadron response of a segmented calorimeter is developed and successfully applied to beam test data. It is based on a principal component analysis of energy deposits in the calorimeter layers, exploiting longitudinal shower development information to improve the measured energy resolution. Corrections for invisible hadronic energy and energy lost in dead material in front of and between the calorimeters of the ATLAS experiment were calculated with simulated Geant4 Monte Carlo events and used to reconstruct the energy of pions impinging on the calorimeters during the 2004 Barrel Combined Beam Test at the CERN H8 area. For pion beams with energies between 20 GeV and 180 GeV, the particle energy is reconstructed within 3% and the energy resolution is improved by between 11% and 25% compared to the resolution at the electromagnetic scale. |
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Address |
[Wheeler, S] Univ Alberta, Dept Phys, Ctr Particle Phys, Edmonton, AB T6G 2G7, Canada[Bernabeu, J; Castillo, MV; Costa, MJ; Escobar, C; Ferrer, A; Garcia, C; Gonzalez-Sevilla, S; Higon, E; Lacasta, C; Garcia, SMI; Mitsou, VA; Ruiz, A; Solans, C; Valero, A; Valls, JA] Ctr Mixto UVEG CSIC, Inst Fis Corpuscular IFIC, ES-46071 Valencia, Spain, Email: kjg@particle.kth.se |
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Iop Publishing Ltd |
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English |
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ISSN |
1748-0221 |
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Notes |
WOS:000294492600001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
744 |
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