Abstract: Purpose: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J -PET) scanner for intra-treatment proton beam range monitoring. Methods: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J -PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread -Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J -PET scanner prototype dedicated to the proton beam range assessment. Results: The investigations indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10-5 coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple -layer dual -head geometry. The results indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for the clinical application, Conclusions: We performed simulation studies demonstrating that the feasibility of the J -PET detector for PET -based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre -clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double -layer cylindrical and triple -layer dual -head J -PET geometry configurations seem promising for future clinical application.

Abstract: Particle physics today faces the challenge of explaining the mystery of dark matter, the origin of matter over anti-matter in the Universe, the origin of the neutrino masses, the apparent fine-tuning of the electro-weak scale, and many other aspects of fundamental physics. Perhaps the most striking frontier to emerge in the search for answers involves new physics at mass scales comparable to familiar matter, below the GeV-scale, or even radically below, down to sub-eV scales, and with very feeble interaction strength. New theoretical ideas to address dark matter and other fundamental questions predict such feebly interacting particles (FIPs) at these scales, and indeed, existing data provide numerous hints for such possibility. A vibrant experimental program to discover such physics is under way, guided by a systematic theoretical approach firmly grounded on the underlying principles of the Standard Model. This document represents the report of the FIPs 2022 workshop, held at CERN between the 17 and 21 October 2022 and aims to give an overview of these efforts, their motivations, and the decadal goals that animate the community involved in the search for FIPs.

Abstract: We predict femtoscopy correlation functions for S-wave D(s)ϕ pairs of lightest pseudoscalar open-charm mesons and Goldstone bosons from next-to-leading-order unitarized heavy-meson chiral perturbation theory amplitudes. The effect of the two-state structure around 2300 MeV can be clearly seen in the (S,I)=(0,1/2) Dπ, Dη, and Ds¯K correlation functions, while in the scalar-strange (1,0) sector, the D∗s0(2317)± state lying below the DK threshold produces a depletion of the correlation function near threshold. These exotic states owe their existence to the nonperturbative dynamics of Goldstone-boson scattering off D(s). The predicted correlation functions could be experimentally measured and will shed light into the hadron spectrum, confirming that it should be viewed as more than a collection of quark model states.

Abstract: We consider higher-order QCD corrections to the production of high-mass systems in hadron collisions within the transverse-momentum (q(T)) subtraction formalism. We present amethod to consistently remove the linear power corrections in q(T) which appears when fiducial kinematical cuts are applied on the final state system. We consider explicitly the case of fiducial cross sections for Drell-Yan lepton pair production at the Large Hadron Collider up to next-to-nextto-next-to-leading order (N3LO) in QCD. We have implemented our method within the DYTurbo numerical program and we have obtained perturbative predictions which are in agreement at the permille level with those obtained with local subtraction formalisms up to the next-to-next-toleading order (NNLO). At the N3LO we are able to provide predictions for fiducial cross sections with numerical accuracy at the permille level.

Abstract: Urgent theoretical progress is needed in order to provide an estimate in the Standard Model of the recent measurement by LHCb of direct CP violation in charm-meson two-body decays. Rescattering effects must be taken into account for a meaningful theoretical description of the amplitudes involved in such category of observables, as signaled by the presence of large strong phases. We discuss the computation of the latter effects based on a two-channel coupled dispersion relation, which exploits isospin-zero phase shifts and inelasticity parametrizations of data coming from the rescattering processes ππ→ππ, πK→πK, and ππ→K¯K. The determination of the subtraction constants of the dispersive integrals relies on the leading contributions to the transition amplitudes from the 1/NC counting, where NC is the number of QCD colors. Furthermore, we use the measured values of the branching ratios to help in selecting the nonperturbative inputs in the isospin limit, from which we predict values for the CP asymmetries. We find that the predicted level of CP violation is much below the experimental value.