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Author Muñoz, E.; Ros, A.; Borja-Lloret, M.; Barrio, J.; Dendooven, P.; Oliver, J.F.; Ozoemelam, I.; Roser, J.; Llosa, G.
Title (up) Proton range verification with MACACO II Compton camera enhanced by a neural network for event selection Type Journal Article
Year 2021 Publication Scientific Reports Abbreviated Journal Sci Rep
Volume 11 Issue 1 Pages 9325 - 12pp
Keywords
Abstract The applicability extent of hadron therapy for tumor treatment is currently limited by the lack of reliable online monitoring techniques. An active topic of investigation is the research of monitoring systems based on the detection of secondary radiation produced during treatment. MACACO, a multi-layer Compton camera based on LaBr3 scintillator crystals and SiPMs, is being developed at IFIC-Valencia for this purpose. This work reports the results obtained from measurements of a 150 MeV proton beam impinging on a PMMA target. A neural network trained on Monte Carlo simulations is used for event selection, increasing the signal to background ratio before image reconstruction. Images of the measured prompt gamma distributions are reconstructed by means of a spectral reconstruction code, through which the 4.439 MeV spectral line is resolved. Images of the emission distribution at this energy are reconstructed, allowing calculation of the distal fall-off and identification of target displacements of 3 mm.
Address [Munoz, Enrique; Ros, Ana; Borja-Lloret, Marina; Barrio, John; Oliver, Josep F.; Roser, Jorge; Llosa, Gabriela] Univ Valencia, Inst Fis Corpuscular IFIC, CSIC, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es
Corporate Author Thesis
Publisher Nature Research Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2045-2322 ISBN Medium
Area Expedition Conference
Notes WOS:000651603500001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4836
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Author Hatifi, M.; Di Molfetta, G.; Debbasch, F.; Brachet, M.
Title (up) Quantum walk hydrodynamics Type Journal Article
Year 2019 Publication Scientific Reports Abbreviated Journal Sci Rep
Volume 9 Issue Pages 2989 - 7pp
Keywords
Abstract A simple Discrete-Time Quantum Walk (DTQW) on the line is revisited and given an hydrodynamic interpretation through a novel relativistic generalization of the Madelung transform. Numerical results show that suitable initial conditions indeed produce hydrodynamical shocks and that the coherence achieved in current experiments is robust enough to simulate quantum hydrodynamical phenomena through DTQWs. An analytical computation of the asymptotic quantum shock structure is presented. The non-relativistic limit is explored in the Supplementary Material (SM).
Address [Hatifi, Mohamed] Aix Marseille Univ, CNRS, Ecole Cent Marseille, Inst Fresnel,UMR 7249, F-13013 Marseille, France, Email: giuseppe.dimolfetta@lis-lab.fr
Corporate Author Thesis
Publisher Nature Publishing Group Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2045-2322 ISBN Medium
Area Expedition Conference
Notes WOS:000459799800138 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3923
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Author ANTARES Collaboration (Andre, M. et al); Barrios-Marti, J.; Hernandez-Rey, J.J.; Illuminati, G.; Tönnis, C.; Zornoza, J.D.; Zuñiga, J.
Title (up) Sperm whale long-range echolocation sounds revealed by ANTARES, a deep-sea neutrino telescope Type Journal Article
Year 2017 Publication Scientific Reports Abbreviated Journal Sci Rep
Volume 7 Issue Pages 45517 - 12pp
Keywords
Abstract Despite dedicated research has been carried out to adequately map the distribution of the sperm whale in the Mediterranean Sea, unlike other regions of the world, the species population status is still presently uncertain. The analysis of two years of continuous acoustic data provided by the ANTARES neutrino telescope revealed the year-round presence of sperm whales in the Ligurian Sea, probably associated with the availability of cephalopods in the region. The presence of the Ligurian Sea sperm whales was demonstrated through the real-time analysis of audio data streamed from a cabled-to-shore deep-sea observatory that allowed the hourly tracking of their long-range echolocation behaviour on the Internet. Interestingly, the same acoustic analysis indicated that the occurrence of surface shipping noise would apparently not condition the foraging behaviour of the sperm whale in the area, since shipping noise was almost always present when sperm whales were acoustically detected. The continuous presence of the sperm whale in the region confirms the ecological value of the Ligurian sea and the importance of ANTARES to help monitoring its ecosystems.
Address [Andre, M.; Caballe, A.; Van der Schaar, M.; Solsona, A.; Houegnigan, L.; Zaugg, S.; Sanchez, A. M.; Castell, J. V.; Sole, M.; Vila, F.; Djokic, D.; Vallage, B.] Tech Univ Catalonia, Barcelona Tech UPC, LAB, Rambla Exposicio 24, Barcelona 08800, Spain, Email: michel.andre@upc.edu
Corporate Author Thesis
Publisher Nature Publishing Group Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2045-2322 ISBN Medium
Area Expedition Conference
Notes WOS:000399188000001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3054
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Author Lerendegui-Marco, J.; Balibrea-Correa, J.; Babiano-Suarez, V.; Ladarescu, I.; Domingo-Pardo, C.
Title (up) Towards machine learning aided real-time range imaging in proton therapy Type Journal Article
Year 2022 Publication Scientific Reports Abbreviated Journal Sci Rep
Volume 12 Issue 1 Pages 2735 - 17pp
Keywords
Abstract Compton imaging represents a promising technique for range verification in proton therapy treatments. In this work, we report on the advantageous aspects of the i-TED detector for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that have been specifically designed for neutron-capture nuclear physics experiments, which are characterized by gamma-ray energies spanning up to 5-6 MeV, rather low gamma-ray emission yields and very intense neutron induced gamma-ray backgrounds. Our developments to cope with these three aspects are concomitant with those required in the field of hadron therapy, especially in terms of high efficiency for real-time monitoring, low sensitivity to neutron backgrounds and reliable performance at the high gamma-ray energies. We find that signal-to-background ratios can be appreciably improved with i-TED thanks to its light-weight design and the low neutron-capture cross sections of its LaCl3 crystals, when compared to other similar systems based on LYSO, CdZnTe or LaBr3. Its high time-resolution (CRT similar to 500 ps) represents an additional advantage for background suppression when operated in pulsed HT mode. Each i-TED Compton module features two detection planes of very large LaCl3 monolithic crystals, thereby achieving a high efficiency in coincidence of 0.2% for a point-like 1 MeV gamma-ray source at 5 cm distance. This leads to sufficient statistics for reliable image reconstruction with an array of four i-TED detectors assuming clinical intensities of 10(8) protons per treatment point. The use of a two-plane design instead of three-planes has been preferred owing to the higher attainable efficiency for double time-coincidences than for threefold events. The loss of full-energy events for high energy gamma-rays is compensated by means of machine-learning based algorithms, which allow one to enhance the signal-to-total ratio up to a factor of 2.
Address [Lerendegui-Marco, Jorge; Balibrea-Correa, Javier; Babiano-Suarez, Victor; Ladarescu, Ion; Domingo-Pardo, Cesar] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: jorge.lerendegui@ific.uv.es
Corporate Author Thesis
Publisher Nature Portfolio Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2045-2322 ISBN Medium
Area Expedition Conference
Notes WOS:000757537100018 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 5136
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Author Dorado-Morales, P.; Vilanova, C.; Pena-Garay, C.; Marti, J.M.; Porcar, M.
Title (up) Unveiling Bacterial Interactions through Multidimensional Scaling and Dynamics Modeling Type Journal Article
Year 2015 Publication Scientific Reports Abbreviated Journal Sci Rep
Volume 5 Issue Pages 18396 - 6pp
Keywords
Abstract We propose a new strategy to identify and visualize bacterial consortia by conducting replicated culturing of environmental samples coupled with high-throughput sequencing and multidimensional scaling analysis, followed by identification of bacteria-bacteria correlations and interactions. We conducted a proof of concept assay with pine-tree resin-based media in ten replicates, which allowed detecting and visualizing dynamical bacterial associations in the form of statistically significant and yet biologically relevant bacterial consortia.
Address [Dorado-Morales, Pedro; Vilanova, Cristina; Porcar, Manuel] Univ Valencia, Cavanilles Inst Biodivers & Evolutionary Biol, Valencia 46020, Spain, Email: manuel.porcar@uv.es
Corporate Author Thesis
Publisher Nature Publishing Group Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2045-2322 ISBN Medium
Area Expedition Conference
Notes WOS:000366483800002 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 2483
Permanent link to this record