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Author |
Baran, J. et al; Brzezinski, K. |
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Title  |
Feasibility of the J-PET to monitor the range of therapeutic proton beams |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physica Medica |
Abbreviated Journal |
Phys. Medica |
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Volume |
118 |
Issue |
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Pages |
103301 - 9pp |
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Keywords |
PET; Range monitoring; J-PET; Monte Carlo simulations; Proton radiotherapy |
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Abstract |
Purpose: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J -PET) scanner for intra-treatment proton beam range monitoring. Methods: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J -PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread -Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J -PET scanner prototype dedicated to the proton beam range assessment. Results: The investigations indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10-5 coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple -layer dual -head geometry. The results indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for the clinical application, Conclusions: We performed simulation studies demonstrating that the feasibility of the J -PET detector for PET -based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre -clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double -layer cylindrical and triple -layer dual -head J -PET geometry configurations seem promising for future clinical application. |
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Address |
[Baran, Jakub; Silarski, Michal; Chug, Neha; Coussat, Aurelien; Czerwinski, Eryk; Dadgar, Meysam; Dulski, Kamil; Eliyan, Kavya, V; Gajos, Aleksander; Kacprzak, Krzysztof; Kaplon, Lukasz; Korcyl, Grzegorz; Kozik, Tomasz; Kumar, Deepak; Niedzwiecki, Szymon; Panek, Dominik; Parzych, Szymon; del Rio, Elena Perez; Simbarashe, Moyo; Sharma, Sushil; Shivani; Skurzok, Magdalena; Stepien, Ewa L.; Tayefi, Keyvan; Tayefi, Faranak; Moskal, Pawel] Jagiellonian Univ, Fac Phys Astron & Appl Comp Sci, 11 Lojasiewicza St, PL-30348 Krakow, Poland, Email: jakubbaran92@gmail.com |
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Publisher |
Elsevier Sci Ltd |
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English |
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ISSN |
1120-1797 |
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Conference |
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Notes |
WOS:001178648400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5990 |
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Author |
Guadilla, V.; Algora, A.; Estienne, M.; Fallot, M.; Gelletly, W.; Porta, A.; Rigalleau, L.M.; Stutzmann, J.S. |
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Title |
First measurements with a new fl-electron detector for spectral shape studies |
Type |
Journal Article |
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Year |
2024 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
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Volume |
19 |
Issue |
2 |
Pages |
P02027 - 21pp |
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Keywords |
Detector modelling and simulations I (interaction of radiation with matter; interaction of photons with matter; interaction of hadrons with matter; etc); Instrumentation for radioactive beams (fragmentation devices; fragment and isotope; separators incl. ISOL; isobar separators; ion and atom traps; weak-beam diagnostics; radioactive-beam ion sources); Hybrid detectors; Spectrometers |
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Abstract |
The shape of the electron spectrum emitted in /3 decay carries a wealth of information about nuclear structure and fundamental physics. In spite of that, few dedicated measurements have been made of /3 -spectrum shapes. In this work we present a newly developed detector for /3 electrons based on a telescope concept. A thick plastic scintillator is employed in coincidence with a thin silicon detector. The first measurements employing this detector have been carried out with mono -energetic electrons from the high-energy resolution electron -beam spectrometer at Bordeaux. Here we report on the good reproduction of the experimental spectra of mono -energetic electrons using Monte Carlo simulations. This is a crucial step for future experiments, where a detailed Monte Carlo characterization of the detector is needed to determine the shape of the /3 -electron spectra by deconvolution of the measured spectra with the response function of the detector. A chamber to contain two telescope assemblies has been designed for future /3 -decay experiments at the Ion Guide Isotope Separator On -Line facility in Jyvaskyla, aimed at improving our understanding of reactor antineutrino spectra. |
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Address |
[Guadilla, V.; Estienne, M.; Fallot, M.; Porta, A.; Rigalleau, L. -m.; Stutzmann, J. -s.] Univ Nantes, Subatech, IMT Atlantique, CNRS,IN2P3, F-44307 Nantes, France, Email: vguadilla@fuw.edu.pl |
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Publisher |
IOP Publishing Ltd |
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Language |
English |
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Edition |
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ISSN |
1748-0221 |
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Conference |
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Notes |
WOS:001181748300007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6064 |
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Author |
Becchetti, M.; Bonciani, R.; Cieri, L.; Coro, F.; Ripani, F. |
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Title |
Full top-quark mass dependence in diphoton production at NNLO in QCD |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
848 |
Issue |
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Pages |
138362 - 7pp |
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Keywords |
Collider phenomenology; Diphoton; Top quark; NNLO |
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Abstract |
In this paper we consider the diphoton production in hadronic collisions at the next-to-next-to-leading order (NNLO) in perturbative QCD, taking into account for the first time the full top quark mass dependence up to two loops (full NNLO). We show selected numerical distributions, highlighting the kinematic regions where the massive corrections are more significant. We make use of the recently computed two-loop massive amplitudes for diphoton production in the quark annihilation channel. The remaining massive contributions at NNLO are also considered, and we comment on the weight of the different types of contributions to the full and complete result. |
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Address |
[Becchetti, Matteo] Univ Torino, Dipartimento Fis, Via Pietro Giuria 1, I-10125 Turin, Italy, Email: matteo.becchetti@unito.it; |
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Publisher |
Elsevier |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0370-2693 |
ISBN |
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Conference |
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Notes |
WOS:001131862200001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5873 |
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Author |
HAWC Collaboration (Alfaro, R. et al); Salesa Greus, F. |
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Title |
Galactic Gamma-Ray Diffuse Emission at TeV Energies with HAWC Data |
Type |
Journal Article |
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Year |
2024 |
Publication |
Astrophysical Journal |
Abbreviated Journal |
Astrophys. J. |
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Volume |
961 |
Issue |
1 |
Pages |
104 - 14pp |
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Keywords |
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Abstract |
Galactic gamma-ray diffuse emission (GDE) is emitted by cosmic rays (CRs), ultra-relativistic protons, and electrons, interacting with gas and electromagnetic radiation fields in the interstellar medium. Here we present the analysis of teraelectronvolt diffuse emission from a region of the Galactic plane over the range in longitude of l is an element of[43 degrees, 73 degrees], using data collected with the High Altitude Water Cherenkov (HAWC) detector. Spectral, longitudinal, and latitudinal distributions of the teraelectronvolt diffuse emission are shown. The radiation spectrum is compatible with the spectrum of the emission arising from a CR population with an index similar to that of the observed CRs. When comparing with the DRAGON base model, the HAWC GDE flux is higher by about a factor of 2. Unresolved sources such as pulsar wind nebulae and teraelectronvolt halos could explain the excess emission. Finally, deviations of the Galactic CR flux from the locally measured CR flux may additionally explain the difference between the predicted and measured diffuse fluxes. |
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Address |
[Alfaro, R.; Rojas, D. Avila; Belmont-Moreno, E.; Espinoza, C.; Hernandez, S.; Leon Vargas, H.; Sandoval, A.; Serna-Franco, J.] Univ Nacl Autonoma Mexico, Inst Fis, Ciudad De Mexico, Mexico, Email: amid.nayerhoda@ifj.edu.pl |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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ISSN |
0004-637x |
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Conference |
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Notes |
WOS:001188034600001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6022 |
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Author |
Barrientos, L.; Borja-Lloret, M.; Casaña, J.V.; Dendooven, P.; Garcia Lopez, J.G.; Hueso-Gonzalez, F.; Jiméeez-Ramos, M.C.; Perez-Curbelo, J.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G. |
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Title |
Gamma-ray sources imaging and test-beam results with MACACO III Compton camera |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physica Medica |
Abbreviated Journal |
Phys. Medica |
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Volume |
117 |
Issue |
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Pages |
103199 - 10pp |
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Keywords |
Hadron therapy; Compton camera; Scintillator crystals; Silicon photomultipliers |
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Abstract |
Hadron therapy is a radiotherapy modality which offers a precise energy deposition to the tumors and a dose reduction to healthy tissue as compared to conventional methods. However, methods for real-time monitoring are required to ensure that the radiation dose is deposited on the target. The IRIS group of IFIC-Valencia developed a Compton camera prototype for this purpose, intending to image the Prompt Gammas emitted by the tissue during irradiation. The system detectors are composed of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. After an initial characterization in the laboratory, in order to assess the system capabilities for future experiments in proton therapy centers, different tests were carried out in two facilities: PARTREC (Groningen, The Netherlands) and the CNA cyclotron (Sevilla, Spain). Characterization studies performed at PARTREC indicated that the detectors linearity was improved with respect to the previous version and an energy resolution of 5.2 % FWHM at 511 keV was achieved. Moreover, the imaging capabilities of the system were evaluated with a line source of 68Ge and a point-like source of 241Am-9Be. Images at 4.439 MeV were obtained from irradiation of a graphite target with an 18 MeV proton beam at CNA, to perform a study of the system potential to detect shifts at different intensities. In this sense, the system was able to distinguish 1 mm variations in the target position at different beam current intensities for measurement times of 1800 and 600 s. |
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Address |
[Barrientos, L.; Borja-Lloret, M.; Casana, J. V.; Hueso-Gonzalez, F.; Perez-Curbelo, J.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Luis.Barrientos@ific.uv.es |
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Corporate Author |
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Thesis |
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Publisher |
Elsevier Sci Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1120-1797 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001145147400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5892 |
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