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Author |
Valdes-Cortez, C.; Niatsetski, Y.; Perez-Calatayud, J.; Ballester, F.; Vijande, J. |
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Title  |
A Monte Carlo study of the relative biological effectiveness in surface brachytherapy |
Type |
Journal Article |
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Year |
2022 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
49 |
Issue |
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Pages |
5576-5588 |
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Keywords |
Monte Carlo; relative biological effectiveness; surface HDR brachytherapy |
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Abstract |
Purpose This work aims to simulate clustered DNA damage from ionizing radiation and estimate the relative biological effectiveness (RBE) for radionuclide (rBT)- and electronic (eBT)-based surface brachytherapy through a hybrid Monte Carlo (MC) approach, using realistic models of the sources and applicators. Methods Damage from ionizing radiation has been studied using the Monte Carlo Damage Simulation algorithm using as input the primary electron fluence simulated using a state-of-the-art MC code, PENELOPE-2018. Two Ir-192 rBT applicators, Valencia and Leipzig, one Co-60 source with a Freiburg Flap applicator (reference source), and two eBT systems, Esteya and INTRABEAM, have been included in this study implementing full realizations of their geometries as disclosed by the manufacturer. The role played by filtration and tube kilovoltage has also been addressed. Results For rBT, an RBE value of about 1.01 has been found for the applicators and phantoms considered. In the case of eBT, RBE values for the Esteya system show an almost constant RBE value of about 1.06 for all depths and materials. For INTRABEAM, variations in the range of 1.12-1.06 are reported depending on phantom composition and depth. Modifications in the Esteya system, filtration, and tube kilovoltage give rise to variations in the same range. Conclusions Current clinical practice does not incorporate biological effects in surface brachytherapy. Therefore, the same absorbed dose is administered to the patients independently on the particularities of the rBT or eBT system considered. The almost constant RBE values reported for rBT support that assumption regardless of the details of the patient geometry, the presence of a flattening filter in the applicator design, or even significant modifications in the photon energy spectra above 300 keV. That is not the case for eBT, where a clear dependence on the eBT system and the characteristics of the patient geometry are reported. A complete study specific for each eBT system, including detailed applicator characteristics (size, shape, filtering, among others) and common anatomical locations, should be performed before adopting an existing RBE value. |
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Address |
[Valdes-Cortez, Christian] Hosp Reg Antofagasta, Nucl Med Dept, Antofagasta, Chile, Email: cvalcort@gmail.com |
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Wiley |
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English |
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0094-2405 |
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Conference |
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Notes |
WOS:000811709400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5262 |
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Author |
Keivani, A.; Murase, K.; Petropoulou, M.; Fox, D.B.; Cenko, S.B.; Chaty, S.; Coleiro, A.; DeLaunay, J.J.; Dimitrakoudis, S.; Evans, P.A.; Kennea, J.A.; Marshall, F.E.; Mastichiadis, A.; Osborne, J.P.; Santander, M.; Tohuvavohu, A.; Turley, C.F. |
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Title |
A Multimessenger Picture of the Flaring Blazar TXS 0506+056: Implications for High-energy Neutrino Emission and Cosmic-Ray Acceleration |
Type |
Journal Article |
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Year |
2018 |
Publication |
Astrophysical Journal |
Abbreviated Journal |
Astrophys. J. |
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Volume |
864 |
Issue |
1 |
Pages |
84 - 16pp |
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Keywords |
Lacertae objects: general; BL Lacertae objects: individual (TXS 0506+056); galaxies: active; gamma rays: galaxies; neutrinos; radiation mechanisms: non-thermal |
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Abstract |
Detection of the IceCube-170922A neutrino coincident with the flaring blazar TXS 0506+056, the first and only similar to 3 sigma high-energy neutrino source association to date, offers a potential breakthrough in our understanding of high-energy cosmic particles and blazar physics. We present a comprehensive analysis of TXS. 0506+056 during its flaring state, using newly collected Swift, NuSTAR, and X-shooter data with Fermi observations and numerical models to constrain the blazar's particle acceleration processes and multimessenger (electromagnetic (EM) and high-energy neutrino) emissions. Accounting properly for EM cascades in the emission region, we find a physically consistent picture only within a hybrid leptonic scenario, with gamma-rays produced by external inverse-Compton processes and high-energy neutrinos via a radiatively subdominant hadronic component. We derive robust constraints on the blazar's neutrino and cosmic-ray emissions and demonstrate that, because of cascade effects, the 0.1-100 keV emissions of TXS. 0506+056 serve as a better probe of its hadronic acceleration and highenergy neutrino production processes than its GeV-TeV emissions. If the IceCube neutrino association holds, physical conditions in the TXS. 0506+056 jet must be close to optimal for high-energy neutrino production, and are not favorable for ultrahigh-energy cosmic-ray acceleration. Alternatively, the challenges we identify in generating a significant rate of IceCube neutrino detections from TXS. 0506+056 may disfavor single-zone models, in which.-rays and high-energy neutrinos are produced in a single emission region. In concert with continued operations of the high-energy neutrino observatories, we advocate regular X-ray monitoring of TXS. 0506+056 and other blazars in order to test single-zone blazar emission models, clarify the nature and extent of their hadronic acceleration processes, and carry out the most sensitive possible search for additional multimessenger sources. |
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Address |
[Keivani, A.; Murase, K.; DeLaunay, J. J.; Turley, C. F.] Penn State Univ, Dept Phys, 104 Davey Lab, University Pk, PA 16802 USA, Email: keivani@psu.edu; |
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Publisher |
Iop Publishing Ltd |
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English |
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ISSN |
0004-637x |
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Conference |
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Notes |
WOS:000443293800010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3708 |
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Author |
Real, D.; Calvo, D.; Diaz, A.; Salesa Greus, F.; Sanchez Losa, A. |
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Title |
A Narrow Optical Pulse Emitter Based on LED: NOPELED |
Type |
Journal Article |
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Year |
2022 |
Publication |
Sensors |
Abbreviated Journal |
Sensors |
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Volume |
22 |
Issue |
19 |
Pages |
7683 - 15pp |
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Keywords |
short optical pulse; optical instrumentation |
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Abstract |
Light sources emitting short pulses are needed in many particle physics experiments using optical sensors as they can replicate the light produced by the particles being detected and are also an important calibration and test element. This work presents NOPELED, a light source based on LEDs emitting short optical pulses with typical rise times of less than 3 ns and Full Width at Half Maximum lower than 7 ns. The emission wavelength depends on the model of LED used. Several LED models have been characterized in the range from 405 to 532 nm, although NOPELED can work with LED emitting wavelengths outside of that region. While the wavelength is fixed for a given LED model, the intensity and the frequency of the optical pulse can be controlled. NOPELED, which also has low cost and simple operation, can be operated remotely, making it appropriate for either different physics experiments needing in-place light sources such as astrophysical neutrino detectors using photo-multipliers or positron emission tomography devices using scintillation counters, or, beyond physics, applications needing short pulses of light such as protein fluorescence or chemodetection of heavy metals. |
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Address |
[Real, Diego; Calvo, David; Salesa Greus, Francisco; Sanchez Losa, Agustin] Univ Valencia, IFIC Inst Fis Corpuscular, CSIC, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: real@ific.uv.es; |
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Publisher |
Mdpi |
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English |
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Notes |
WOS:000867935300001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5381 |
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Author |
Dote, A.; Bayar, M.; Xiao, C.W.; Hyodo, T.; Oka, M.; Oset, E. |
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Title |
A narrow quasi-bound state of the DNN system |
Type |
Journal Article |
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Year |
2013 |
Publication |
Nuclear Physics A |
Abbreviated Journal |
Nucl. Phys. A |
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Volume |
914 |
Issue |
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Pages |
499-504 |
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Keywords |
Nuclear system with a D meson; Few-body system; Variational calculation; Faddeev calculation |
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Abstract |
We have investigated a charmed system of DNN (composed of two nucleons and a D meson) by a complementary study with a variational calculation and a Faddeev calculation with fixed-center approximation (Faddeev-FCA). In the present study, we employ a DN potential based on a vector-meson exchange picture in which a resonant A(c)(2595) is dynamically generated as a DN quasi-bound state, similarly to the A(1405) as a (K) over barN one in the strange sector. As a result of the study of variational calculation with an effective DN potential and three kinds of NN potentials, the DNN(J(pi) =0(-), I = 1/2) is found to be a narrow quasi-bound state below A(c)(2595)N threshold: total binding energy similar to 225 MeV and mesonic decay width similar to 25 MeV. On the other hand, the J(pi) =1(-) state is considered to be a scattering state of A(c)(2595) and a nucleon. These results are essentially supported by the Faddeev-FCA calculation. By the analysis of the variational wave function, we have found a unique structure in the DNN(J(pi) = 0, I = 1/2) such that the D meson stays around the center of the total system due to the heaviness of the D meson. |
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Address |
[Dote, A.] High Energy Accelerator Res Org KEK, IPNS, KEK Theory Ctr, Tsukuba, Ibaraki 3050801, Japan, Email: dote@post.kek.jp |
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Publisher |
Elsevier Science Bv |
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Language |
English |
Summary Language |
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Original Title |
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Abbreviated Series Title |
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Edition |
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ISSN |
0375-9474 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000324847700071 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1602 |
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Author |
Stuhl, L.; Krasznahorkay, A.; Csatlos, M.; Algora, A.; Gulyas, J.; Kalinka, G.; Timar, J.; Kalantar-Nayestanaki, N.; Rigollet, C.; Bagchi, S.; Najafi, M.A. |
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Title |
A neutron spectrometer for studying giant resonances with (p,n) reactions in inverse kinematics |
Type |
Journal Article |
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Year |
2014 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
736 |
Issue |
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Pages |
1-9 |
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Keywords |
Low-energy neutron spectrometer; Neutron time-of-flight measurements; ELENS; VM2000 wrapping |
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Abstract |
A neutron spectrometer, the European Low-Energy Neutron Spectrometer (ELENS), has been constructed to study exotic nuclei in inverse-kinematics experiments. The spectrometer, which consists of plastic scintillator bars, can be operated in the neutron energy range of 100 keV-10 MeV. The neutron energy is determined using the time-of-flight technique, while the position of the neutron detection is deduced from the time-difference information from photomultipliers attached to both ends of each bar. A novel wrapping method has been developed for the plastic scintillators. The array has a larger than 25% detection efficiency for neutrons of approximately 500 keV in kinetic energy and an angular resolution of less than 1 degrees. Details of the design, construction and experimental tests of the spectrometer will be presented. |
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Address |
[Stuhl, L.; Krasznahorkay, A.; Csatlos, M.; Algora, A.; Gulyas, J.; Kalinka, G.; Timar, J.] Hungarian Acad Sci, Inst Nucl Res, ATOMKI, Debrecen, Hungary, Email: stuhl@atomki.hu |
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Corporate Author |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000329404000002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1695 |
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Author |
LHCb Collaboration (Aaij, R. et al); Martinez-Vidal, F.; Oyanguren, A.; Ruiz Valls, P.; Sanchez Mayordomo, C. |
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Title |
A new algorithm for identifying the flavour of B-s(0) mesons at LHCb |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
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Volume |
11 |
Issue |
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Pages |
P05010 - 23pp |
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Keywords |
Analysis and statistical methods; Particle identification methods; Pattern recognition; cluster finding; calibration and fitting methods |
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Abstract |
A new algorithm for the determination of the initial flavour of B-s(0) mesons is presented. The algorithm is based on two neural networks and exploits the b hadron production mechanism at a hadron collider. The first network is trained to select charged kaons produced in association with the B-s(0) meson. The second network combines the kaon charges to assign the B-s(0) flavour and estimates the probability of a wrong assignment. The algorithm is calibrated using data corresponding to an integrated luminosity of 3 fb(-1) collected by the LHCb experiment in proton-proton collisions at 7 and 8 TeV centre-of-mass energies. The calibration is performed in two ways: by resolving the B-s(0)-B-s(0) flavour oscillations in B-s(0) -> D-s(-)pi(+) decays, and by analysing flavour-specific B-s2*(5840)(0) -> B+K- decays. The tagging power measured in B-s(0) -> D-s(-)pi(+) decays is found to be (1.80 +/- 0.19 ( stat) +/- 0.18 (syst))%, which is an improvement of about 50% compared to a similar algorithm previously used in the LHCb experiment. |
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Address |
[Bediaga, I.; De Miranda, J. M.; Rodrigues, F. Ferreira; Gomes, A.; Massafferri, A.; Rodrigues, B. Osorio; dos Reis, A. C.; Rodrigues, A. B.] CBPF, Rio De Janeiro, Brazil, Email: mirco.dorigo@cern.ch |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1748-0221 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000377851700033 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2731 |
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Author |
Egea Canet, F.J. et al; Gadea, A.; Huyuk, T. |
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Title |
A New Front-End High-Resolution Sampling Board for the New-Generation Electronics of EXOGAM2 and NEDA Detectors |
Type |
Journal Article |
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Year |
2015 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
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Volume |
62 |
Issue |
3 |
Pages |
1056-1062 |
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Keywords |
Acquisition in HP-Ge detectors; high-speed ADCs; low-noise electronics design |
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Abstract |
This paper presents the final design and results of the FADC Mezzanine for the EXOGAM (EXOtic GAMma array spectrometer) and NEDA (Neutron Detector Array) detectors. The measurements performed include those of studying the effective number of bits, the energy resolution using HP-Ge detectors, as well as timing histograms and discrimination performance. Finally, the conclusion shows how a common digitizing device has been integrated in the experimental environment of two very different detectors which combine both low-noise acquisition and fast sampling rates. Not only the integration fulfilled the expected specifications on both systems, but it also showed how a study of synergy between detectors could lead to the reduction of resources and time by applying a common strategy. |
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Address |
[Egea Canet, F. J.; Gonzalez, V.; Sanchis, E.] Univ Valencia, Dept Elect Engn, Escola Tecn Super Engn, Valencia, Spain, Email: jaegea@ific.uv.es |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
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Language |
English |
Summary Language |
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Series Issue |
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Edition |
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ISSN |
0018-9499 |
ISBN |
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Area |
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Conference |
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Notes |
WOS:000356458000028 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2278 |
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Author |
Vinyoles, N.; Serenelli, A.M.; Villante, F.L.; Basu, S.; Bergstrom, J.; Gonzalez-Garcia, M.C.; Maltoni, M.; Pena-Garay, C.; Song, N.Q. |
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Title |
A New Generation of Standard Solar Models |
Type |
Journal Article |
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Year |
2017 |
Publication |
Astrophysical Journal |
Abbreviated Journal |
Astrophys. J. |
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Volume |
835 |
Issue |
2 |
Pages |
202 - 16pp |
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Keywords |
neutrinos; Sun: abundances; Sun: Helioseismology; Sun: interior |
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Abstract |
We compute a new generation of standard solar models (SSMs) that includes recent updates on some important nuclear reaction rates and a more consistent treatment of the equation of state. Models also include a novel and flexible treatment of opacity uncertainties based on opacity kernels, required in. light of recent theoretical and experimental works on radiative opacity. Two large sets of SSMs, each based on a different canonical set of solar abundances with high and low metallicity (Z), are computed to determine model uncertainties and correlations among different observables. We present detailed comparisons of high-and low-Z models against different ensembles of solar observables,. including solar neutrinos, surface helium abundance, depth of the. convective envelope, and sound speed profile. A global comparison, including all observables, yields a p-value of 2.7 sigma for the high-Z model and 4.7 sigma for the low-Z one. When the sound speed differences in the narrow region of 0.65 < r/R-circle dot < 0.70 are excluded from the analysis, results are 0.9 sigma and 3.0 sigma for high-and low-Z models respectively. These results show that. high-Z models agree well with solar data but have a systematic problem right below the bottom of the convective envelope linked to steepness of molecular weight and temperature gradients, and that low-Z models lead to a much more general disagreement with solar data. We also show that, while simple parametrizations of opacity uncertainties can strongly alleviate the solar abundance problem, they are insufficient to substantially improve the agreement of SSMs with helioseismic data beyond that obtained for high-Z models due to the intrinsic correlations of theoretical predictions. |
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Address |
[Vinyoles, Nuria; Serenelli, Aldo M.] CSIC IEEC, Inst Ciencies Espai, Campus UAB,Carrer Can Magrans S-N, E-08193 Barcelona, Spain, Email: vinyoles@ice.csic.es; |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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ISSN |
0004-637x |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000401145700018 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3145 |
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Author |
Alioli, S.; Fuster, J.; Irles Quiles, A.; Moch, S.; Uwer, P.; Vos, M. |
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Title |
A new observable to measure the top quark mass at hadron colliders |
Type |
Journal Article |
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Year |
2012 |
Publication |
Pramana-Journal of Physics |
Abbreviated Journal |
Pramana-J. Phys. |
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Volume |
79 |
Issue |
4 |
Pages |
809-812 |
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Keywords |
Top quark; mass; pole mass; NLO; cross-section; t(t)over-bar plus jet; POWHEG; perturbative QCD |
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Abstract |
The t (t) over bar + jet + X differential cross-section in proton-proton collisions at 7 TeV centre of mass energy is investigated with respect to its sensitivity to the top quark mass. The analysis includes higher order QCD corrections at NLO. The impact of the renormalization scale (mu(R)), the factorization (mu(F)) scale and of the choice of different proton's PDF (parton distribution function) has been evaluated. In this study it is concluded that differential jet rates offer a promising option for alternative mass measurements of the top quark, with theoretical uncertainties below 1 GeV. |
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Address |
[Fuster, Juan; Irles, Adrian; Vos, Marcel] Univ Valencia, Ctr Mixte, CSIC, IFIC, E-46071 Valencia, Spain, Email: airqui@ific.uv.es |
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Publisher |
Indian Acad Sciences |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0304-4289 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000310875900021 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1200 |
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Author |
Bernabeu, J.; Navarro-Salas, J. |
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Title |
A Non-Local Action for Electrodynamics: Duality Symmetry and the Aharonov-Bohm Effect, Revisited |
Type |
Journal Article |
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Year |
2019 |
Publication |
Symmetry-Basel |
Abbreviated Journal |
Symmetry-Basel |
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Volume |
11 |
Issue |
10 |
Pages |
1191 - 13pp |
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Keywords |
non-local action; electrodynamics; electromagnetic duality symmetry; Aharonov-Bohm effect |
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Abstract |
A non-local action functional for electrodynamics depending on the electric and magnetic fields, instead of potentials, has been proposed in the literature. In this work we elaborate and improve this proposal. We also use this formalism to confront the electric-magnetic duality symmetry of the electromagnetic field and the Aharonov-Bohm effect, two subtle aspects of electrodynamics that we examine in a novel way. We show how the former can be derived from the simple harmonic oscillator character of vacuum electrodynamics, while also demonstrating how the magnetic version of the latter naturally arises in an explicitly non-local manner. |
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Address |
[Bernabeu, Joan] Ludwig Maximilians Univ Munchen, Phys Dept, Theresienstr 37, D-80333 Munich, Germany, Email: Joan.Bernabeu@physik.uni-muenchen.de; |
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Publisher |
Mdpi |
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Language |
English |
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Notes |
WOS:000495457600005 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4192 |
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