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Author Baran, J. et al; Brzezinski, K.
Title (up) Feasibility of the J-PET to monitor the range of therapeutic proton beams Type Journal Article
Year 2024 Publication Physica Medica Abbreviated Journal Phys. Medica
Volume 118 Issue Pages 103301 - 9pp
Keywords PET; Range monitoring; J-PET; Monte Carlo simulations; Proton radiotherapy
Abstract Purpose: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J -PET) scanner for intra-treatment proton beam range monitoring. Methods: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J -PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread -Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J -PET scanner prototype dedicated to the proton beam range assessment. Results: The investigations indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10-5 coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple -layer dual -head geometry. The results indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for the clinical application, Conclusions: We performed simulation studies demonstrating that the feasibility of the J -PET detector for PET -based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre -clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double -layer cylindrical and triple -layer dual -head J -PET geometry configurations seem promising for future clinical application.
Address [Baran, Jakub; Silarski, Michal; Chug, Neha; Coussat, Aurelien; Czerwinski, Eryk; Dadgar, Meysam; Dulski, Kamil; Eliyan, Kavya, V; Gajos, Aleksander; Kacprzak, Krzysztof; Kaplon, Lukasz; Korcyl, Grzegorz; Kozik, Tomasz; Kumar, Deepak; Niedzwiecki, Szymon; Panek, Dominik; Parzych, Szymon; del Rio, Elena Perez; Simbarashe, Moyo; Sharma, Sushil; Shivani; Skurzok, Magdalena; Stepien, Ewa L.; Tayefi, Keyvan; Tayefi, Faranak; Moskal, Pawel] Jagiellonian Univ, Fac Phys Astron & Appl Comp Sci, 11 Lojasiewicza St, PL-30348 Krakow, Poland, Email: jakubbaran92@gmail.com
Corporate Author Thesis
Publisher Elsevier Sci Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1120-1797 ISBN Medium
Area Expedition Conference
Notes WOS:001178648400001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5990
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Author Guadilla, V.; Algora, A.; Estienne, M.; Fallot, M.; Gelletly, W.; Porta, A.; Rigalleau, L.M.; Stutzmann, J.S.
Title (up) First measurements with a new fl-electron detector for spectral shape studies Type Journal Article
Year 2024 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 19 Issue 2 Pages P02027 - 21pp
Keywords Detector modelling and simulations I (interaction of radiation with matter; interaction of photons with matter; interaction of hadrons with matter; etc); Instrumentation for radioactive beams (fragmentation devices; fragment and isotope; separators incl. ISOL; isobar separators; ion and atom traps; weak-beam diagnostics; radioactive-beam ion sources); Hybrid detectors; Spectrometers
Abstract The shape of the electron spectrum emitted in /3 decay carries a wealth of information about nuclear structure and fundamental physics. In spite of that, few dedicated measurements have been made of /3 -spectrum shapes. In this work we present a newly developed detector for /3 electrons based on a telescope concept. A thick plastic scintillator is employed in coincidence with a thin silicon detector. The first measurements employing this detector have been carried out with mono -energetic electrons from the high-energy resolution electron -beam spectrometer at Bordeaux. Here we report on the good reproduction of the experimental spectra of mono -energetic electrons using Monte Carlo simulations. This is a crucial step for future experiments, where a detailed Monte Carlo characterization of the detector is needed to determine the shape of the /3 -electron spectra by deconvolution of the measured spectra with the response function of the detector. A chamber to contain two telescope assemblies has been designed for future /3 -decay experiments at the Ion Guide Isotope Separator On -Line facility in Jyvaskyla, aimed at improving our understanding of reactor antineutrino spectra.
Address [Guadilla, V.; Estienne, M.; Fallot, M.; Porta, A.; Rigalleau, L. -m.; Stutzmann, J. -s.] Univ Nantes, Subatech, IMT Atlantique, CNRS,IN2P3, F-44307 Nantes, France, Email: vguadilla@fuw.edu.pl
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:001181748300007 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 6064
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Author Ortiz Arciniega, J.L.; Carrio, F.; Valero, A.
Title (up) FPGA implementation of a deep learning algorithm for real-time signal reconstruction in particle detectors under high pile-up conditions Type Journal Article
Year 2019 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 14 Issue Pages P09002 - 13pp
Keywords Data processing methods; Pattern recognition; cluster finding; calibration and fitting methods; Simulation methods and programs
Abstract The analog signals generated in the read-out electronics of particle detectors are shaped prior to the digitization in order to improve the signal to noise ratio (SNR). The real amplitude of the analog signal is then obtained using digital filters, which provides information about the energy deposited in the detector. The classical digital filters have a good performance in ideal situations with Gaussian electronic noise and no pulse shape distortion. However, high-energy particle colliders, such as the Large Hadron Collider (LHC) at CERN, can produce multiple simultaneous events, which produce signal pileup. The performance of classical digital filters deteriorates in these conditions since the signal pulse shape gets distorted. In addition, this type of experiments produces a high rate of collisions, which requires high throughput data acquisitions systems. In order to cope with these harsh requirements, new read-out electronics systems are based on high-performance FPGAs, which permit the utilization of more advanced real-time signal reconstruction algorithms. In this paper, a deep learning method is proposed for real-time signal reconstruction in high pileup particle detectors. The performance of the new method has been studied using simulated data and the results are compared with a classical FIR filter method. In particular, the signals and FIR filter used in the ATLAS Tile Calorimeter are used as benchmark. The implementation, resources usage and performance of the proposed Neural Network algorithm in FPGA are also presented.
Address [Ortiz Arciniega, J. L.] Univ Valencia, Avinguda Univ S-N, Burjassot, Spain, Email: orarjo@alumni.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:000486990000002 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4150
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Author Moline, A.; Ibarra, A.; Palomares-Ruiz, S.
Title (up) Future sensitivity of neutrino telescopes to dark matter annihilations from the cosmic diffuse neutrino signal Type Journal Article
Year 2015 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.
Volume 06 Issue 6 Pages 005 - 34pp
Keywords dark matter theory; dark matter simulations; cosmological neutrinos
Abstract Cosmological observations and cold dark matter N-body simulations indicate that our Universe is populated by numerous halos, where dark matter particles annihilate, potentially producing Standard Model particles. In this paper we calculate the contribution to the diffuse neutrino background from dark matter annihilations in halos at all redshifts and we estimate the future sensitivity to the annihilation cross section of neutrino telescopes such as IceCube or ANTARES. We consider various parametrizations to describe the internal halo properties and for the halo mass function in order to bracket the theoretical uncertainty in the limits from the modeling of the cosmological annihilation flux. We find that observations of the cosmic diffuse neutrino flux at large angular distances from the galactic center lead to constraints on the dark matter annihilation cross section which are complementary to ( and for some extrapolations of the astrophysical parameters, better than) those stemming from observations of the Milky Way halo, especially for neutrino telescopes not pointing directly to the Milky Way center, as is the case of IceCube.
Address [Moline, Angeles] Univ Tecn Lisboa, Inst Super Tecn, CFTP, P-1049001 Lisbon, Portugal, Email: maria.moline@ist.utl.pt;
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1475-7516 ISBN Medium
Area Expedition Conference
Notes WOS:000359215400006 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 2369
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Author n_TOF Collaboration (Zugec, P. et al); Domingo-Pardo, C.; Giubrone, G.; Tain, J.L.
Title (up) GEANT4 simulation of the neutron background of the C6D6 set-up for capture studies at n_TOF Type Journal Article
Year 2014 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 760 Issue Pages 57-67
Keywords GEANT4 simulations; Neutron time of flight; Neutron background; N_TOF; Neutron capture
Abstract The neutron sensitivity of the Cr6D6 detector setup used at nTOF facility for capture measurements has been studied by means of detailed GEANT4 simulations. A realistic software replica of the entire nTOF experimental hall, including the neutron beam line, sample, detector supports and the walls of the experimental area has been implemented in the simulations. The simulations have been analyzed in the same manner as experimental data, in particular by applying the Pulse Height Weighting Technique. The simulations have been validated against a measurement of the neutron background performed with a(nat)-C sample, showing an excellent agreement above 1 keV. At lower energies, an additional component in the measured C-nat yield has been discovered, which prevents the use of C-nat data for neutron background estimates at neutron energies below a few hundred eV. The origin and time structure of the neutron background have been derived from the simulations. Examples of the neutron background for two different samples are demonstrating the important role of accurate simulations of the neutron background in capture cross-section measurements.
Address [Zugec, P.; Bosnar, D.] Univ Zagreb, Fac Sci, Dept Phys, Zagreb 41000, Croatia, Email: pzugec@phy.hr
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000338350500008 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1828
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Author Aguiar, P.; Rafecas, M.; Ortuño, J.E.; Kontaxakis, G.; Santos, A.; Pavia, J.; Rosetti, M.
Title (up) Geometrical and Monte Carlo projectors in 3D PET reconstruction Type Journal Article
Year 2010 Publication Medical Physics Abbreviated Journal Med. Phys.
Volume 37 Issue 11 Pages 5691-5702
Keywords 3D PET; iterative reconstruction; list-mode reconstruction; ray-tracing techniques; Monte Carlo simulation; system response matrix
Abstract Purpose: In the present work, the authors compare geometrical and Monte Carlo projectors in detail. The geometrical projectors considered were the conventional geometrical Siddon ray-tracer (S-RT) and the orthogonal distance-based ray-tracer (OD-RT), based on computing the orthogonal distance from the center of image voxel to the line-of-response. A comparison of these geometrical projectors was performed using different point spread function (PSF) models. The Monte Carlo-based method under consideration involves an extensive model of the system response matrix based on Monte Carlo simulations and is computed off-line and stored on disk. Methods: Comparisons were performed using simulated and experimental data of the commercial small animal PET scanner rPET. Results: The results demonstrate that the orthogonal distance-based ray-tracer and Siddon ray-tracer using PSF image-space convolutions yield better images in terms of contrast and spatial resolution than those obtained after using the conventional method and the multiray-based S-RT. Furthermore, the Monte Carlo-based method yields slight improvements in terms of contrast and spatial resolution with respect to these geometrical projectors. Conclusions: The orthogonal distance-based ray-tracer and Siddon ray-tracer using PSF image-space convolutions represent satisfactory alternatives to factorizing the system matrix or to the conventional on-the-fly ray-tracing methods for list-mode reconstruction, where an extensive modeling based on Monte Carlo simulations is unfeasible.
Address [Aguiar, Pablo] Univ Santiago de Compostela, Dept Fis Particulas, Complexo Hosp Univ Santiago de Compostela, Fdn IDICHUS IDIS, Santiago De Compostela, Spain, Email: pablo.aguiar.fernandez@sergas.es
Corporate Author Thesis
Publisher Amer Assoc Physicists Medicine Amer Inst Physics Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0094-2405 ISBN Medium
Area Expedition Conference
Notes ISI:000283747600015 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ elepoucu @ Serial 338
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Author Campanario, F.; Kubocz, M.
Title (up) Higgs boson CP-properties of the gluonic contributions in Higgs plus three jet production via gluon fusion at the LHC Type Journal Article
Year 2014 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.
Volume 10 Issue 10 Pages 173 - 16pp
Keywords QCD Phenomenology; Monte Carlo Simulations
Abstract in high energy hadronic collisions, a general CP-violating Higgs boson Phi with accompanying jets can be efficiently produced via gluon fusion, which is mediated by heavy quark loops. In this article, we study the dominant sub-channel gg -> ggg Phi of the gluon fusion production process with triple real emission corrections at order alpha(5)(s). We go beyond the heavy top-quark approximation and include the full mass dependence of the top- and bottom-quark contributions. Furthermore, in a specific model we demonstrate the features of our program and show the impact of bottom-quark loop contributions in combination with large values of tan beta on differential distributions sensitive to CP-rneasurements of the Higgs boson.
Address [Campanario, Francisco] Univ Valencia CSIC, IFIC, Div Theory, E-46100 Valencia, Spain, Email: francisco.campanario@ific.uv.es;
Corporate Author Thesis
Publisher Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1029-8479 ISBN Medium
Area Expedition Conference
Notes WOS:000344652800003 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 2007
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Author DUNE Collaboration (Abud, A.A. et al); Amedo, P.; Antonova, M.; Barenboim, G.; Cervera-Villanueva, A.; De Romeri, V.; Garcia-Peris, M.A.; Martin-Albo, J.; Martinez-Mirave, P.; Mena, O.; Molina Bueno, L.; Novella, P.; Pompa, F.; Rocabado Rocha, J.L.; Sorel, M.; Tortola, M.; Tuzi, M.; Valle, J.W.F.; Yahlali, N.
Title (up) Highly-parallelized simulation of a pixelated LArTPC on a GPU Type Journal Article
Year 2023 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 18 Issue 4 Pages P04034 - 35pp
Keywords Detector modelling and simulations II (electric fields, charge transport, multiplication, and induction, pulse formation, electron emission, etc); Simulation methods and programs; Nobleliquid detectors (scintillation, ionization, double-phase); Time projection Chambers (TPC)
Abstract The rapid development of general-purpose computing on graphics processing units (GPGPU) is allowing the implementation of highly-parallelized Monte Carlo simulation chains for particle physics experiments. This technique is particularly suitable for the simulation of a pixelated charge readout for time projection chambers, given the large number of channels that this technology employs. Here we present the first implementation of a full microphysical simulator of a liquid argon time projection chamber (LArTPC) equipped with light readout and pixelated charge readout, developed for the DUNE Near Detector. The software is implemented with an end-to-end set of GPU-optimized algorithms. The algorithms have been written in Python and translated into CUDA kernels using Numba, a just-in-time compiler for a subset of Python and NumPy instructions. The GPU implementation achieves a speed up of four orders of magnitude compared with the equivalent CPU version. The simulation of the current induced on 103 pixels takes around 1 ms on the GPU, compared with approximately 10 s on the CPU. The results of the simulation are compared against data from a pixel-readout LArTPC prototype.
Address [Isenhower, L.] Abilene Christian Univ, Abilene, TX 79601 USA, Email: roberto@lbl.gov
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:000986658100009 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5551
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Author Roser, J.; Muñoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J.F.
Title (up) Image reconstruction for a multi-layer Compton telescope: an analytical model for three interaction events Type Journal Article
Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 65 Issue 14 Pages 145005 - 17pp
Keywords Compton camera; Compton imaging; hadron therapy; image reconstruction; lm-mlem; monte carlo simulations; multi-layer Compton telescope
Abstract Compton Cameras are electronically collimated photon imagers suitable for sub-MeV to few MeV gamma-ray detection. Such features are desirable to enablein vivorange verification in hadron therapy, through the detection of secondary Prompt Gammas. A major concern with this technique is the poor image quality obtained when the incoming gamma-ray energy is unknown. Compton Cameras with more than two detector planes (multi-layer Compton Cameras) have been proposed as a solution, given that these devices incorporate more signal sequences of interactions to the conventional two interaction events. In particular, three interaction events convey more spectral information as they allow inferring directly the incident gamma-ray energy. A three-layer Compton Telescope based on continuous Lanthanum (III) Bromide crystals coupled to Silicon Photomultipliers is being developed at the IRIS group of IFIC-Valencia. In a previous work we proposed a spectral reconstruction algorithm for two interaction events based on an analytical model for the formation of the signal. To fully exploit the capabilities of our prototype, we present here an extension of the model for three interaction events. Analytical expressions of the sensitivity and the System Matrix are derived and validated against Monte Carlo simulations. Implemented in a List Mode Maximum Likelihood Expectation Maximization algorithm, the proposed model allows us to obtain four-dimensional (energy and position) images by using exclusively three interaction events. We are able to recover the correct spectrum and spatial distribution of gamma-ray sources when ideal data are employed. However, the uncertainties associated to experimental measurements result in a degradation when real data from complex structures are employed. Incorrect estimation of the incident gamma-ray interaction positions, and missing deposited energy associated with escaping secondaries, have been identified as the causes of such degradation by means of a detailed Monte Carlo study. As expected, our current experimental resolution and efficiency to three interaction events prevents us from correctly recovering complex structures of radioactive sources. However, given the better spectral information conveyed by three interaction events, we expect an improvement of the image quality of conventional Compton imaging when including such events. In this regard, future development includes the incorporation of the model assessed in this work to the two interaction events model in order to allow using simultaneously two and three interaction events in the image reconstruction.
Address [Roser, J.; Munoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J. F.] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: Jorge.Roser@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000552701600001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4481
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Author Jueid, A.; Kip, J.; Ruiz de Austri, R.; Skands, P.
Title (up) Impact of QCD uncertainties on antiproton spectra from dark-matter annihilation Type Journal Article
Year 2023 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.
Volume 04 Issue 4 Pages 068 - 15pp
Keywords cosmic ray theory; dark matter simulations; cosmic ray experiments; Frequentist statistics
Abstract Dark-matter particles that annihilate or decay can undergo complex sequences of processes, including strong and electromagnetic radiation, hadronisation, and hadron de-cays, before particles that are stable on astrophysical time scales are produced. Antiprotons produced in this way may leave footprints in experiments such as AMS-02. Several groups have reported an excess of events in the antiproton flux in the rigidity range of 10-20 GV. However, the theoretical modeling of baryon production is not straightforward and relies in part on phenomenological models in Monte Carlo event generators. In this work, we assess the impact of QCD uncertainties on the spectra of antiprotons from dark-matter annihila-tion. As a proof-of-principle, we show that for a two-parameter model that depends only on the thermally-averaged annihilation cross section ((o -v)) and the dark-matter mass (Mx), QCD uncertainties can affect the best-fit mass by up to ti 14% (with large uncertainties for large DM masses), depending on the choice of Mx and the annihilation channel (bb over bar or W+W-), and (o -v) by up to ti 10%. For comparison, changes to the underlying diffusion parameters are found to be within 1%-5%, and the results are also quite resilient to the choice of cosmic-ray propagation model. These findings indicate that QCD uncertainties need to be included in future DM analyses. To facilitate full-fledged analyses, we provide the spectra in tabulated form including QCD uncertainties and code snippets to perform mass interpolations and quick DM fits. The code can be found in this GitHub [1] repository.
Address [Jueid, Adil] Inst Basic Sci IBS, Ctr Theoret Phys Universe, Daejeon 34126, South Korea, Email: adiljueid@ibs.re.kr;
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1475-7516 ISBN Medium
Area Expedition Conference
Notes WOS:000985779900007 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5532
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