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Albiol, A., Albiol, F., Paredes, R., Plasencia-Martinez, J. M., Blanco Barrio, A., Garcia Santos, J. M., et al. (2022). A comparison of Covid-19 early detection between convolutional neural networks and radiologists. Insights Imaging, 13(1), 122–12pp.
Abstract: Background The role of chest radiography in COVID-19 disease has changed since the beginning of the pandemic from a diagnostic tool when microbiological resources were scarce to a different one focused on detecting and monitoring COVID-19 lung involvement. Using chest radiographs, early detection of the disease is still helpful in resource-poor environments. However, the sensitivity of a chest radiograph for diagnosing COVID-19 is modest, even for expert radiologists. In this paper, the performance of a deep learning algorithm on the first clinical encounter is evaluated and compared with a group of radiologists with different years of experience. Methods The algorithm uses an ensemble of four deep convolutional networks, Ensemble4Covid, trained to detect COVID-19 on frontal chest radiographs. The algorithm was tested using images from the first clinical encounter of positive and negative cases. Its performance was compared with five radiologists on a smaller test subset of patients. The algorithm's performance was also validated using the public dataset COVIDx. Results Compared to the consensus of five radiologists, the Ensemble4Covid model achieved an AUC of 0.85, whereas the radiologists achieved an AUC of 0.71. Compared with other state-of-the-art models, the performance of a single model of our ensemble achieved nonsignificant differences in the public dataset COVIDx. Conclusion The results show that the use of images from the first clinical encounter significantly drops the detection performance of COVID-19. The performance of our Ensemble4Covid under these challenging conditions is considerably higher compared to a consensus of five radiologists. Artificial intelligence can be used for the fast diagnosis of COVID-19.
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Balazs, C. et al, Mamuzic, J., & Ruiz de Austri, R. (2021). A comparison of optimisation algorithms for high-dimensional particle and astrophysics applications. J. High Energy Phys., 05(5), 108–46pp.
Abstract: Optimisation problems are ubiquitous in particle and astrophysics, and involve locating the optimum of a complicated function of many parameters that may be computationally expensive to evaluate. We describe a number of global optimisation algorithms that are not yet widely used in particle astrophysics, benchmark them against random sampling and existing techniques, and perform a detailed comparison of their performance on a range of test functions. These include four analytic test functions of varying dimensionality, and a realistic example derived from a recent global fit of weak-scale supersymmetry. Although the best algorithm to use depends on the function being investigated, we are able to present general conclusions about the relative merits of random sampling, Differential Evolution, Particle Swarm Optimisation, the Covariance Matrix Adaptation Evolution Strategy, Bayesian Optimisation, Grey Wolf Optimisation, and the PyGMO Artificial Bee Colony, Gaussian Particle Filter and Adaptive Memory Programming for Global Optimisation algorithms.
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Zhai, Y. J., Giare, W., van de Bruck, C., Di Valentino, E., Mena, O., & Nunes, R. C. (2023). A consistent view of interacting dark energy from multiple CMB probes. J. Cosmol. Astropart. Phys., 07(7), 032–16pp.
Abstract: We analyze a cosmological model featuring an interaction between dark energy and dark matter in light of the measurements of the Cosmic Microwave Background released by three independent experiments: the most recent data by the Planck satellite and the Atacama Cosmology Telescope, and WMAP (9-year data). We show that different combinations of the datasets provide similar results, always favoring an interacting dark sector with a 95% C.L. significance in the majority of the cases. Remarkably, such a preference remains consistent when cross-checked through independent probes, while always yielding a value of the expansion rate H0 consistent with the local distance ladder measurements. We investigate the source of this preference by scrutinizing the angular power spectra of temperature and polarization anisotropies as measured by different experiments.
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Hueso-Gonzalez, F., Casaña Copado, J. V., Fernandez Prieto, A., Gallas Torreira, A., Lemos Cid, E., Ros Garcia, A., et al. (2022). A dead-time-free data acquisition system for prompt gamma-ray measurements during proton therapy treatments. Nucl. Instrum. Methods Phys. Res. A, 1033, 166701–9pp.
Abstract: In cancer patients undergoing proton therapy, a very intense secondary radiation is produced during the treatment, which lasts around one minute. About one billion prompt gamma-rays are emitted per second, and their detection with fast scintillation detectors is useful for monitoring a correct beam delivery. To cope with the expected count rate and pile-up, as well as the scarce statistics due to the short treatment duration, we developed an eidetic data acquisition system capable of continuously digitizing the detector signal with a high sampling rate and without any dead time. By streaming the fully unprocessed waveforms to the computer, complex pile-up decomposition algorithms can be applied and optimized offline. We describe the data acquisition architecture and the multiple experimental tests designed to verify the sustained data throughput speed and the absence of dead time. While the system is tailored for the proton therapy environment, the methodology can be deployed in any other field requiring the recording of raw waveforms at high sampling rates with zero dead time.
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Hirn, J., Garcia, J. E., Montesinos-Navarro, A., Sanchez-Martin, R., Sanz, V., & Verdu, M. (2022). A deep Generative Artificial Intelligence system to predict species coexistence patterns. Methods Ecol. Evol., 13, 1052–1061.
Abstract: Predicting coexistence patterns is a current challenge to understand diversity maintenance, especially in rich communities where these patterns' complexity is magnified through indirect interactions that prevent their approximation with classical experimental approaches. We explore cutting-edge Machine Learning techniques called Generative Artificial Intelligence (GenAI) to predict species coexistence patterns in vegetation patches, training generative adversarial networks (GAN) and variational AutoEncoders (VAE) that are then used to unravel some of the mechanisms behind community assemblage. The GAN accurately reproduces real patches' species composition and plant species' affinity to different soil types, and the VAE also reaches a high level of accuracy, above 99%. Using the artificially generated patches, we found that high-order interactions tend to suppress the positive effects of low-order interactions. Finally, by reconstructing successional trajectories, we could identify the pioneer species with larger potential to generate a high diversity of distinct patches in terms of species composition. Understanding the complexity of species coexistence patterns in diverse ecological communities requires new approaches beyond heuristic rules. Generative Artificial Intelligence can be a powerful tool to this end as it allows to overcome the inherent dimensionality of this challenge.
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PTOLEMY Collaboration(Betti, M. G. et al), de Salas, P. F., Gariazzo, S., & Pastor, S. (2019). A design for an electromagnetic filter for precision energy measurements at the tritium endpoint. Prog. Part. Nucl. Phys., 106, 120–131.
Abstract: We present a detailed description of the electromagnetic filter for the PTOLEMY project to directly detect the Cosmic Neutrino Background (CNB). Starting with an initial estimate for the orbital magnetic moment, the higher-order drift process of E x B is configured to balance the gradient-B drift motion of the electron in such a way as to guide the trajectory into the standing voltage potential along the mid-plane of the filter. As a function of drift distance along the length of the filter, the filter zooms in with exponentially increasing precision on the transverse velocity component of the electron kinetic energy. This yields a linear dimension for the total filter length that is exceptionally compact compared to previous techniques for electromagnetic filtering. The parallel velocity component of the electron kinetic energy oscillates in an electrostatic harmonic trap as the electron drifts along the length of the filter. An analysis of the phase-space volume conservation validates the expected behavior of the filter from the adiabatic invariance of the orbital magnetic moment and energy conservation following Liouville's theorem for Hamiltonian systems. (C) 2019 Elsevier B.V. All rights reserved.
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ATLAS Collaboration. (2022). A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery. Nature, 607(7917), 52–59.
Abstract: The standard model of particle physics(1-4) describes the known fundamental particles and forces that make up our Universe, with the exception of gravity. One of the central features of the standard model is a field that permeates all of space and interacts with fundamental particles(5-9). The quantum excitation of this field, known as the Higgs field, manifests itself as the Higgs boson, the only fundamental particle with no spin. In 2012, a particle with properties consistent with the Higgs boson of the standard model was observed by the ATLAS and CMS experiments at the Large Hadron Collider at CERN10,11. Since then, more than 30 times as many Higgs bosons have been recorded by the ATLAS experiment, enabling much more precise measurements and new tests of the theory. Here, on the basis of this larger dataset, we combine an unprecedented number of production and decay processes of the Higgs boson to scrutinize its interactions with elementary particles. Interactions with gluons, photons, and W and Z bosons-the carriers of the strong, electromagnetic and weak forces-are studied in detail. Interactions with three third-generation matter particles (bottom (b) and top (t) quarks, and tau leptons (tau)) are well measured and indications of interactions with a second-generation particle (muons, mu) are emerging. These tests reveal that the Higgs boson discovered ten years ago is remarkably consistent with the predictions of the theory and provide stringent constraints on many models of new phenomena beyond the standard model.
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Delhom, A., Olmo, G. J., & Singh, P. (2023). A diffeomorphism invariant family of metric-affine actions for loop cosmologies. J. Cosmol. Astropart. Phys., 06(6), 059–21pp.
Abstract: In loop quantum cosmology (LQC) the big bang singularity is generically resolved by a big bounce. This feature holds even when modified quantization prescriptions of the Hamiltonian constraint are used such as in mLQC-I and mLQC-II. While the later describes an effective description qualitatively similar to that of standard LQC, the former describes an asymmetric evolution with an emergent Planckian de-Sitter pre-bounce phase even in the absence of a potential. We consider the potential relation of these canonically quantized non-singular models with effective actions based on a geometric description. We find a 3-parameter family of metric-affine f (R) theories which accurately approximate the effective dynamics of LQC and mLQC-II in all regimes and mLQC-I in the post-bounce phase. Two of the parameters are fixed by enforcing equivalence at the bounce, and the background evolution of the relevant observables can be fitted with only one free parameter. It is seen that the non-perturbative effects of these loop cosmologies are universally encoded by a logarithmic correction that only depends on the bounce curvature of the model. In addition, we find that the best fit value of the free parameter can be very approximately written in terms of fundamental parameters of the underlying quantum description for the three models. The values of the best fits can be written in terms of the bounce density in a simple manner, and the values for each model are related to one another by a proportionality relation involving only the Barbero-Immirzi parameter.
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Di Valentino, E., & Mena, O. (2021). A fake interacting dark energy detection? Mon. Not. Roy. Astron. Soc., 500(1), L22–L26.
Abstract: Models involving an interaction between the dark matter and the dark energy sectors have been proposed to alleviate the long-standing Hubble constant tension. In this paper, we analyse whether the constraints and potential hints obtained for these interacting models remain unchanged when using simulated Planck data. Interestingly, our simulations indicate that a dangerous fake detection for a non-zero interaction among the dark matter and the dark energy fluids could arise when dealing with current cosmic microwave background (CMB) Planck measurements alone. The very same hypothesis is tested against future CMB observations, finding that only cosmic variance limited polarization experiments, such as PICO or PRISM, could be able to break the existing parameter degeneracies and provide reliable cosmological constraints. This paper underlines the extreme importance of confronting the results arising from data analyses with those obtained with simulations when extracting cosmological limits within exotic cosmological scenarios.
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Balibrea-Correa, J., Lerendegui-Marco, J., Calvo, D., Caballero, L., Babiano, V., Ladarescu, I., et al. (2021). A first prototype of C6D6 total-energy detector with SiPM readout for neutron capture time-of-flight experiments. Nucl. Instrum. Methods Phys. Res. A, 985, 164709–8pp.
Abstract: Low efficiency total-energy detectors (TEDs) are one of the main tools for neutron capture cross section measurements utilizing the time-of-flight (TOF) technique. State-of-the-art TEDs are based on a C6D6 liquid-scintillation cell optically coupled to a fast photomultiplier tube. The large photomultiplier tube represents yet a significant contribution to the so-called neutron sensitivity background, which is one of the most conspicuous sources of uncertainty in this type of experiments. Here we report on the development of a first prototype of a TED based on a silicon-photomultiplier (SiPM) readout, thus resulting in a lightweight and much more compact detector. Apart from the envisaged improvement in neutron sensitivity, the new system uses low voltage (+28 V) and low current supply (-50 mA), which is more practical than the-kV supply required by conventional photomultipliers. One important difficulty hindering the earlier implementation of SiPM readout for this type of detector was the large capacitance for the output signal when all pixels of a SiPM array are summed together. The latter leads to long pulse rise and decay times, which are not suitable for time-of-flight experiments. In this work we demonstrate the feasibility of a Schottky-diode multiplexing readout approach, that allows one to preserve the excellent timing properties of SiPMs, hereby paving the way for their implementation in future neutron TOF experiments.
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