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Author de Salas, P.F.; Forero, D.V.; Gariazzo, S.; Martinez-Mirave, P.; Mena, O.; Ternes, C.A.; Tortola, M.; Valle, J.W.F. url  doi
openurl 
  Title (up) 2020 global reassessment of the neutrino oscillation picture Type Journal Article
  Year 2021 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.  
  Volume 02 Issue 2 Pages 071 - 36pp  
  Keywords Beyond Standard Model; Neutrino Physics  
  Abstract We present an updated global fit of neutrino oscillation data in the simplest three-neutrino framework. In the present study we include up-to-date analyses from a number of experiments. Concerning the atmospheric and solar sectors, besides the data considered previously, we give updated analyses of IceCube DeepCore and Sudbury Neutrino Observatory data, respectively. We have also included the latest electron antineutrino data collected by the Daya Bay and RENO reactor experiments, and the long-baseline T2K and NO nu A measurements, as reported in the Neutrino 2020 conference. All in all, these new analyses result in more accurate measurements of theta (13), theta (12), Delta m212 and Delta m312. The best fit value for the atmospheric angle theta (23) lies in the second octant, but first octant solutions remain allowed at similar to 2.4 sigma. Regarding CP violation measurements, the preferred value of delta we obtain is 1.08 pi (1.58 pi) for normal (inverted) neutrino mass ordering. The global analysis still prefers normal neutrino mass ordering with 2.5 sigma statistical significance. This preference is milder than the one found in previous global analyses. These new results should be regarded as robust due to the agreement found between our Bayesian and frequentist approaches. Taking into account only oscillation data, there is a weak/moderate preference for the normal neutrino mass ordering of 2.00 sigma. While adding neutrinoless double beta decay from the latest Gerda, CUORE and KamLAND-Zen results barely modifies this picture, cosmological measurements raise the preference to 2.68 sigma within a conservative approach. A more aggressive data set combination of cosmological observations leads to a similar preference for normal with respect to inverted mass ordering, namely 2.70 sigma. This very same cosmological data set provides 2 sigma upper limits on the total neutrino mass corresponding to Sigma m(nu)< 0.12 (0.15) eV in the normal (inverted) neutrino mass ordering scenario. The bounds on the neutrino mixing parameters and masses presented in this up-to-date global fit analysis include all currently available neutrino physics inputs.  
  Address [de Salas, P. F.] Stockholm Univ, Oskar Klein Ctr Cosmoparticle Phys, Dept Phys, AlbaNova, S-10691 Stockholm, Sweden, Email: pablo.fernandez@fysik.su.se;  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1029-8479 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000618343000003 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 4727  
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Author Celis, A.; Fuentes-Martin, J.; Serodio, H. url  doi
openurl 
  Title (up) A class of invisible axion models with FCNCs at tree level Type Journal Article
  Year 2014 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.  
  Volume 12 Issue 12 Pages 167 - 53pp  
  Keywords Beyond Standard Model; CP violation; Global Symmetries  
  Abstract We build a class of invisible axion models with tree-level Flavor Changing Neutral Currents completely controlled by the fermion mixing matrices. The scalar sector of these models contains three-Higgs doublets and a complex scalar gauge singlet, with the same fermionic content as in the Standard Model. A horizontal Peccei-Quinn symmetry provides a solution to the strong CP problem and predicts the existence of a very light and weakly coupled pseudo-Goldstone boson, the invisible axion or familon. A phenomenological analysis is performed taking into account familon searches in rare kaon and muon decays, astrophysical considerations and axion searches via axion-photon conversion. Drastic differences are found in the axion properties of different models due to the strong hierarchy of the CKM matrix, making some of the models considered much more constrained than others. We also obtain that a rich variety of these models avoid the domain wall problem. A possible mechanism to protect the solution to the strong CP problem against gravitational effects is also discussed.  
  Address [Celis, Alejandro; Fuentes-Martin, Javier] Univ Valencia, CSIC, IFIC, E-46071 Valencia, Spain, Email: alejandro.celis@ific.uv.es;  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1029-8479 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000347160000001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2067  
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Author Bordes, J.; Chan, H.M.; Tsun, S.S. url  doi
openurl 
  Title (up) A closer study of the framed standard model yielding testable new physics plus a hidden sector with dark matter candidates Type Journal Article
  Year 2018 Publication International Journal of Modern Physics A Abbreviated Journal Int. J. Mod. Phys. A  
  Volume 33 Issue 33 Pages 1850195 - 75pp  
  Keywords Gauge field theories; beyond the standard model; composite models; mass and mixing of fermions; dark matter  
  Abstract This closer study of the FSM (1) retains the earlier results of Ref. 1 in offering explanation for the existence of three fermion generations, as well as the hierarchical mass and mixing patterns of leptons and quarks; (II) predicts a vector boson G with mass of order TeV which mixes gamma with and Z of the standard model. The subsequent deviations from the standard mixing scheme are calculable in terms of the G mass. While these deviations for (i) mz – mw, (ii) Gamma(Z -> l (+)l( -)), and (iii) F(Z -> hadrons) are all within present experimental errors so long as mG > 1 TeV, they should soon be detectable if the G mass is not too much bigger; (III) suggests that in parallel to the standard sector familiar to us, there is another where the roles of flavour and colour are interchanged. Though quite as copiously populated and as vibrant in self-interactions as our own, it communicates but little with the standard sector except via mixing through a couple of known portals, one of which is the gamma – Z – G complex noted in (II), and the other is a scalar complex which includes the standard model Higgs. As a result, the new sectors paper. appears hidden to us as we appear hidden to them, and so its lowest members with masses of order 10 MeV, being electrically neutral and seemingly stable, but abundant, may make eligible candidates as constituents of dark matter. A more detailed summary of these results together with some remarks on the model's special theoretical features can be found in the last section of this paper.  
  Address [Bordes, Jose] Univ Valencia, CSIC, Ctr Mixto, Dept Fis Teor, Calle Dr Moliner 50, E-46100 Burjassot, Valencia, Spain, Email: bordes@uv.es;  
  Corporate Author Thesis  
  Publisher World Scientific Publ Co Pte Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0217-751x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000453027500004 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 3844  
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Author Alekhin, S. et al; Hernandez, P. url  doi
openurl 
  Title (up) A facility to search for hidden particles at the CERN SPS: the SHiP physics case Type Journal Article
  Year 2016 Publication Reports on Progress in Physics Abbreviated Journal Rep. Prog. Phys.  
  Volume 79 Issue 12 Pages 124201 - 137pp  
  Keywords beyond the standard model physics; intensity frontier experiment; hidden sectors; heavy neutral leptons; dark photons  
  Abstract This paper describes the physics case for a new fixed target facility at CERN SPS. The SHiP (search for hidden particles) experiment is intended to hunt for new physics in the largely unexplored domain of very weakly interacting particles with masses below the Fermi scale, inaccessible to the LHC experiments, and to study tau neutrino physics. The same proton beam setup can be used later to look for decays of tau-leptons with lepton flavour number non-conservation, tau -> 3 μand to search for weakly-interacting sub-GeV dark matter candidates. We discuss the evidence for physics beyond the standard model and describe interactions between new particles and four different portals-scalars, vectors, fermions or axion-like particles. We discuss motivations for different models, manifesting themselves via these interactions, and how they can be probed with the SHiP experiment and present several case studies. The prospects to search for relatively light SUSY and composite particles at SHiP are also discussed. We demonstrate that the SHiP experiment has a unique potential to discover new physics and can directly probe a number of solutions of beyond the standard model puzzles, such as neutrino masses, baryon asymmetry of the Universe, dark matter, and inflation.  
  Address [Alekhin, Sergey] DESY, Platanenallee 6, D-15738 Zeuthen, Germany, Email: oleg.ruchayskiy@cern.ch  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0034-4885 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000387025400001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2852  
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Author Fonseca, R.M.; Hirsch, M. url  doi
openurl 
  Title (up) A flipped 331 model Type Journal Article
  Year 2016 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.  
  Volume 08 Issue 8 Pages 003 - 12pp  
  Keywords Beyond Standard Model; Gauge Symmetry; Neutrino Physics  
  Abstract Models based on the extended SU(3)(C) x SU(3)(L) x U(1)(X) (331) gauge group usually follow a common pattern: two families of left-handed quarks are placed in anti triplet representations of the SU(3)(L) group; the remaining quark family, as well as the left-handed leptons, are assigned to triplets (or vice-versa). In this work we present a flipped 331 model where this scheme is reversed: all three quark families are in the same representation and it is the lepton families which are discriminated by the gauge symmetry. We discuss fermion masses and mixing, as well as Z' interactions, in a minimal model implementing this idea.  
  Address [Fonseca, Renato M.; Hirsch, Martin] Univ Valencia, CSIC, Inst Fis Corpuscular, AHEP Grp, Parc Cient Paterna,Calle Jose Beltran, E-46980 Paterna, Valencia, Spain, Email: renato.fonseca@ific.uv.es;  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1029-8479 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000381218300003 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 2782  
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Author Ballester, F.; Tedgren, A.C.; Granero, D.; Haworth, A.; Mourtada, F.; Fonseca, G.P.; Zourari, K.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.L.; Thomson, R.M.; Verhaegen, F.; Vijande, J.; Ma, Y.Z.; Beaulieu, L. doi  openurl
  Title (up) A generic high-dose rate Ir-192 brachytherapy source for evaluation of model-based dose calculations beyond the TG-43 formalism Type Journal Article
  Year 2015 Publication Medical Physics Abbreviated Journal Med. Phys.  
  Volume 42 Issue 6 Pages 3048-3062  
  Keywords Ir-192; HDR brachytherapy; Monte Carlo methods; model-based dose calculation; TG-186  
  Abstract Purpose: In order to facilitate a smooth transition for brachytherapy dose calculations from the American Association of Physicists in Medicine (AAPM) Task Group No. 43 (TG-43) formalism to model-based dose calculation algorithms (MBDCAs), treatment planning systems (TPSs) using a MBDCA require a set of well-defined test case plans characterized by Monte Carlo (MC) methods. This also permits direct dose comparison to TG-43 reference data. Such test case plans should be made available for use in the software commissioning process performed by clinical end users. To this end, a hypothetical, generic high-dose rate (HDR) Ir-192 source and a virtual water phantom were designed, which can be imported into a TPS. Methods: A hypothetical, generic HDR Ir-192 source was designed based on commercially available sources as well as a virtual, cubic water phantom that can be imported into any TPS in DICOM format. The dose distribution of the generic Ir-192 source when placed at the center of the cubic phantom, and away from the center under altered scatter conditions, was evaluated using two commercial MBDCAs [Oncentra (R) Brachy with advanced collapsed-cone engine (ACE) and BrachyVision AcuRos (TM)]. Dose comparisons were performed using state-of-the-art MC codes for radiation transport, including ALGEBRA, BrachyDose, GEANT4, MCNP5, MCNP6, and pENELopE2008. The methodologies adhered to recommendations in the AAPM TG-229 report on high-energy brachytherapy source dosimetry. TG-43 dosimetry parameters, an along-away dose-rate table, and primary and scatter separated (PSS) data were obtained. The virtual water phantom of (201)(3) voxels (1 mm sides) was used to evaluate the calculated dose distributions. Two test case plans involving a single position of the generic HDR Ir-192 source in this phantom were prepared: (i) source centered in the phantom and (ii) source displaced 7 cm laterally from the center. Datasets were independently produced by different investigators. MC results were then compared against dose calculated using TG-43 and MBDCA methods. Results: TG-43 and PSS datasets were generated for the generic source, the PSS data for use with the ACE algorithm. The dose-rate constant values obtained from seven MC simulations, performed independently using different codes, were in excellent agreement, yielding an average of 1.1109 +/- 0.0004 cGy/(h U) (k = 1, Type A uncertainty). MC calculated dose-rate distributions for the two plans were also found to be in excellent agreement, with differences within type A uncertainties. Differences between commercial MBDCA and MC results were test, position, and calculation parameter dependent. On average, however, these differences were within 1% for ACUROS and 2% for ACE at clinically relevant distances. Conclusions: A hypothetical, generic HDR Ir-192 source was designed and implemented in two commercially available TPSs employing different MBDCAs. Reference dose distributions for this source were benchmarked and used for the evaluation of MBDCA calculations employing a virtual, cubic water phantom in the form of a CT DICOM image series. The implementation of a generic source of identical design in all TPSs using MBDCAs is an important step toward supporting univocal commissioning procedures and direct comparisons between TPSs.  
  Address [Ballester, Facundo] Univ Valencia, Dept Atom Mol & Nucl Phys, E-46100 Burjassot, Spain, Email: Facundo.Ballester@uv.es  
  Corporate Author Thesis  
  Publisher Amer Assoc Physicists Medicine Amer Inst Physics Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0094-2405 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000356998300031 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2315  
Permanent link to this record
 

 
Author Ma, Y.Z.; Vijande, J.; Ballester, F.; Tedgren, A.C.; Granero, D.; Haworth, A.; Mourtada, F.; Fonseca, G.P.; Zourari, K.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.; Chamberland, M.J.P.; Thomson, R.M.; Verhaegen, F.; Beaulieu, L. doi  openurl
  Title (up) A generic TG-186 shielded applicator for commissioning model-based dose calculation algorithms for high-dose-rate Ir-192 brachytherapy Type Journal Article
  Year 2017 Publication Medical Physics Abbreviated Journal Med. Phys.  
  Volume 44 Issue 11 Pages 5961-5976  
  Keywords Ir-192; HDR brachytherapy; model based dose calculation; Monte Carlo methods; shielded applicator; TG-186  
  Abstract PurposeA joint working group was created by the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) with the charge, among others, to develop a set of well-defined test case plans and perform calculations and comparisons with model-based dose calculation algorithms (MBDCAs). Its main goal is to facilitate a smooth transition from the AAPM Task Group No. 43 (TG-43) dose calculation formalism, widely being used in clinical practice for brachytherapy, to the one proposed by Task Group No. 186 (TG-186) for MBDCAs. To do so, in this work a hypothetical, generic high-dose rate (HDR) Ir-192 shielded applicator has been designed and benchmarked. MethodsA generic HDR Ir-192 shielded applicator was designed based on three commercially available gynecological applicators as well as a virtual cubic water phantom that can be imported into any DICOM-RT compatible treatment planning system (TPS). The absorbed dose distribution around the applicator with the TG-186 Ir-192 source located at one dwell position at its center was computed using two commercial TPSs incorporating MBDCAs (Oncentra((R)) Brachy with Advanced Collapsed-cone Engine, ACE, and BrachyVision ACUROS) and state-of-the-art Monte Carlo (MC) codes, including ALGEBRA, BrachyDose, egs_brachy, Geant4, MCNP6, and Penelope2008. TPS-based volumetric dose distributions for the previously reported source centered in water and source displaced test cases, and the new source centered in applicator test case, were analyzed here using the MCNP6 dose distribution as a reference. Volumetric dose comparisons of TPS results against results for the other MC codes were also performed. Distributions of local and global dose difference ratios are reported. ResultsThe local dose differences among MC codes are comparable to the statistical uncertainties of the reference datasets for the source centered in water and source displaced test cases and for the clinically relevant part of the unshielded volume in the source centered in applicator case. Larger local differences appear in the shielded volume or at large distances. Considering clinically relevant regions, global dose differences are smaller than the local ones. The most disadvantageous case for the MBDCAs is the one including the shielded applicator. In this case, ACUROS agrees with MC within [-4.2%, +4.2%] for the majority of voxels (95%) while presenting dose differences within [-0.12%, +0.12%] of the dose at a clinically relevant reference point. For ACE, 95% of the total volume presents differences with respect to MC in the range [-1.7%, +0.4%] of the dose at the reference point. ConclusionsThe combination of the generic source and generic shielded applicator, together with the previously developed test cases and reference datasets (available in the Brachytherapy Source Registry), lay a solid foundation in supporting uniform commissioning procedures and direct comparisons among treatment planning systems for HDR Ir-192 brachytherapy.  
  Address [Ma, Yunzhi; Beaulieu, Luc] CHU Quebec, Dept Radio Oncol & Axe Oncol, Ctr Rech, Quebec City, PQ G1R 2J6, Canada, Email: yunzhi.Ma@crchuq.ulaval.ca  
  Corporate Author Thesis  
  Publisher Wiley Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0094-2405 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000414970800039 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 3370  
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Author ATLAS Collaboration (Abat, E. et al); Bernabeu Verdú, J.; Castillo Gimenez, V.; Costa, M.J.; Escobar, C.; Ferrer, A.; Garcia, C.; Gonzalez-Sevilla, S.; Higon-Rodriguez, E.; Lacasta, C.; Marti-Garcia, S.; Mitsou, V.A.; Ruiz, A.; Solans, C.; Valero, A.; Valls Ferrer, J.A. url  doi
openurl 
  Title (up) A layer correlation technique for pion energy calibration at the 2004 ATLAS Combined Beam Test Type Journal Article
  Year 2011 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.  
  Volume 6 Issue Pages P06001 - 35pp  
  Keywords Calorimeter methods; Pattern recognition, cluster finding, calibration and fitting methods; Calorimeters; Detector modelling and simulations I (interaction of radiation with matter, interaction of photons with matter, interaction of hadrons with matter, etc)  
  Abstract A new method for calibrating the hadron response of a segmented calorimeter is developed and successfully applied to beam test data. It is based on a principal component analysis of energy deposits in the calorimeter layers, exploiting longitudinal shower development information to improve the measured energy resolution. Corrections for invisible hadronic energy and energy lost in dead material in front of and between the calorimeters of the ATLAS experiment were calculated with simulated Geant4 Monte Carlo events and used to reconstruct the energy of pions impinging on the calorimeters during the 2004 Barrel Combined Beam Test at the CERN H8 area. For pion beams with energies between 20 GeV and 180 GeV, the particle energy is reconstructed within 3% and the energy resolution is improved by between 11% and 25% compared to the resolution at the electromagnetic scale.  
  Address [Wheeler, S] Univ Alberta, Dept Phys, Ctr Particle Phys, Edmonton, AB T6G 2G7, Canada[Bernabeu, J; Castillo, MV; Costa, MJ; Escobar, C; Ferrer, A; Garcia, C; Gonzalez-Sevilla, S; Higon, E; Lacasta, C; Garcia, SMI; Mitsou, VA; Ruiz, A; Solans, C; Valero, A; Valls, JA] Ctr Mixto UVEG CSIC, Inst Fis Corpuscular IFIC, ES-46071 Valencia, Spain, Email: kjg@particle.kth.se  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1748-0221 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000294492600001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ elepoucu @ Serial 744  
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Author Brown, J.M.C.; Dimmock, M.R.; Gillam, J.E.; Paganin, D.M. doi  openurl
  Title (up) A low energy bound atomic electron Compton scattering model for Geant4 Type Journal Article
  Year 2014 Publication Nuclear Instruments & Methods in Physics Research B Abbreviated Journal Nucl. Instrum. Methods Phys. Res. B  
  Volume 338 Issue Pages 77-88  
  Keywords Compton scattering; Geant4; Radiation transport modelling; Monte Carlo method  
  Abstract A two-body fully relativistic three-dimensional scattering framework has been utilised to develop an alternative Compton scattering computational model to those adapted from Ribberfors' work for Monte Carlo modelling of Compton scattering. Using a theoretical foundation that ensures the conservation of energy and momentum in the relativistic impulse approximation, this new model, the Monash University Compton scattering model, develops energy and directional algorithms for both the scattered photon and ejected Compton electron from first principles. The Monash University Compton scattering model was developed to address the limitation of the Compton electron directionality algorithms of other computational models adapted from Ribberfors' work. Here the development of the Monash University Compton scattering model, including its implementation in a Geant4 low energy electromagnetic physics class, G4LowEPComptonModel, is outlined. Assessment of the performance of G4LowEPComptonModel was undertaken in two steps: (1) comparison with respect to the two standard Compton scattering classes of Geant4 version 9.5, G4LivermoreComptonModel and G4PenelopeComptonModel, and (2) experimental comparison with respect to Compton electron kinetic energy spectra obtained from the Compton scattering of 662 key photons off the K-shell of gold. Both studies illustrate that the Monash University Compton scattering model, and in turn G4LowEPComptonModel, is a viable replacement for the majority of computational models that have been adapted from Ribberfors' work. It was also shown that the Monash University Compton scattering model is able to reproduce the Compton scattering triply differential cross-section Compton electron kinetic energy spectra of 662 keV photons K-shell scattering off of gold to within experimental uncertainty.  
  Address [Brown, J. M. C.; Paganin, D. M.] Monash Univ, Sch Phys, Clayton, Vic 3800, Australia, Email: jeremy.brown@cern.ch  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0168-583x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000343390400012 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1973  
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Author Peppa, V.; Thomson, R.M.; Enger, S.A.; Fonseca, G.P.; Lee, C.N.; Lucero, J.N.E.; Mourtada, F.; Siebert, F.A.; Vijande, J.; Papagiannis, P. doi  openurl
  Title (up) A MC-based anthropomorphic test case for commissioning model-based dose calculation in interstitial breast 192-Ir HDR brachytherapy Type Journal Article
  Year 2023 Publication Medical Physics Abbreviated Journal Med. Phys.  
  Volume 50 Issue 7 Pages 4675-4687  
  Keywords anthropomorphic phantom; commissioning; HDR brachytherapy; model based dose calculation algorithms; Monte Carlo  
  Abstract PurposeTo provide the first clinical test case for commissioning of Ir-192 brachytherapy model-based dose calculation algorithms (MBDCAs) according to the AAPM TG-186 report workflow. Acquisition and Validation MethodsA computational patient phantom model was generated from a clinical multi-catheter Ir-192 HDR breast brachytherapy case. Regions of interest (ROIs) were contoured and digitized on the patient CT images and the model was written to a series of DICOM CT images using MATLAB. The model was imported into two commercial treatment planning systems (TPSs) currently incorporating an MBDCA. Identical treatment plans were prepared using a generic Ir-192 HDR source and the TG-43-based algorithm of each TPS. This was followed by dose to medium in medium calculations using the MBDCA option of each TPS. Monte Carlo (MC) simulation was performed in the model using three different codes and information parsed from the treatment plan exported in DICOM radiation therapy (RT) format. Results were found to agree within statistical uncertainty and the dataset with the lowest uncertainty was assigned as the reference MC dose distribution. Data Format and Usage NotesThe dataset is available online at ,. Files include the treatment plan for each TPS in DICOM RT format, reference MC dose data in RT Dose format, as well as a guide for database users and all files necessary to repeat the MC simulations. Potential ApplicationsThe dataset facilitates the commissioning of brachytherapy MBDCAs using TPS embedded tools and establishes a methodology for the development of future clinical test cases. It is also useful to non-MBDCA adopters for intercomparing MBDCAs and exploring their benefits and limitations, as well as to brachytherapy researchers in need of a dosimetric and/or a DICOM RT information parsing benchmark. Limitations include specificity in terms of radionuclide, source model, clinical scenario, and MBDCA version used for its preparation.  
  Address [Peppa, Vasiliki; Papagiannis, Panagiotis] Natl & Kapodistrian Univ Athens, Med Sch, Med Phys Lab, Athens, Greece, Email: ppapagi@med.uoa.gr  
  Corporate Author Thesis  
  Publisher Wiley Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0094-2405 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000989616100001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5529  
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