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Author Soriano, A.; Gonzalez, A.; Orero, A.; Moliner, L.; Carles, M.; Sanchez, F.; Benlloch, J.M.; Correcher, C.; Carrilero, V.; Seimetz, M.
Title Attenuation correction without transmission scan for the MAMMI breast PET Type Journal Article
Year 2011 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 648 Issue Pages S75-S78
Keywords Breast PET; Attenuation correction
Abstract Whole-body Positron Emission Tomography (PET) scanners are required in order to span large Fields of View (FOV). Therefore, reaching the sensitivity and spatial resolution required for early stage breast tumor detection is not straightforward. MAMMI is a dedicated breast PET scanner with a ring geometry designed to provide PET images with a spatial resolution as high as 1.5 mm, being able to detect small breast tumors ( < 1 cm). The patient lays down in prone position during the scan, thus making possible to image the whole breast, up to regions close to the base of the pectoral without the requirement of breast compression. Attenuation correction (AC) for PET data improves the image quality and the quantitative accuracy of radioactivity distribution determination. In dedicated, high resolution breast cancer scanners, this correction would enhance the proper diagnosis in early disease stages. In whole-body PET scanners, AC is usually taken into account with the use of transmission scans, either by external radioactive rod sources or by Computed Tomography (CT). This considerably increases the radiation dose administered to the patient and time needed for the exploration. In this work we propose a method for breast shape identification by means of PET image segmentation. The breast shape identification will be used for the determination of the AC. For the case of a specific breast PET scanner the procedure we propose should provide AC similar to that obtained by transmission scans as we take advantage of the breast anatomical simplicity. Experimental validation of the proposed approach with a dedicated breast PET prototype is also presented. The main advantage of this method is an important dose reduction since the transmission scan is not required.
Address [Soriano, A.; Orero, A.; Moliner, L.; Carles, M.; Sanchez, F.; Benlloch, J. M.] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46980 Paterna, Spain, Email: soriano@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume (down) Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000305376900021 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 1069
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Author Gran, R.; Nieves, J.; Sanchez, F.; Vicente Vacas, M.J.
Title Neutrino-nucleus quasi-elastic and 2p2h interactions up to 10 GeV Type Journal Article
Year 2013 Publication Physical Review D Abbreviated Journal Phys. Rev. D
Volume 88 Issue 11 Pages 113007 - 10pp
Keywords
Abstract We extend to 10 GeV results from a microscopic calculation of charged-current neutrino-nucleus reactions that do not produce a pion in the final state. For the class of events coming from neutrino interactions with two nucleons producing two holes (2p2h), limiting the calculation to three-momentum transfers less than 1.2 GeV produces a two-dimensional distribution in momentum and energy transfer that is roughly constant as a function of energy. The cross section for 2p2h interactions approximately scales with the number of nucleons for isoscalar nuclei, similar to the quasi-elastic cross section. When limited to momentum transfers below 1.2 GeV, the cross section is 26% of the quasi-elastic cross section at 3 GeV, but 14% if we neglect a Delta(1232) resonance absorption component. The same quantities are 33% and 17% for antineutrinos. For the quasi-elastic interactions, the full nuclear model with long range correlations produces an even larger, but approximately constant distortion of the shape of the four-momentum transfer at all energies above 2 GeV. The 2p2h enhancement and long-range correlation distortions to the cross section for these interactions are significant enough they should be observable in precision experiments to measure neutrino oscillations and neutrino interactions at these energies, but also balance out and produce less total distortion than each effect does individually.
Address [Gran, R.] Univ Minnesota, Dept Phys, Duluth, MN 55812 USA
Corporate Author Thesis
Publisher Amer Physical Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume (down) Series Issue Edition
ISSN 1550-7998 ISBN Medium
Area Expedition Conference
Notes WOS:000328692000001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1666
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Author Ros, A.; Lerche, C.W.; Sebastia, A.; Sanchez, F.; Benlloch, J.M.
Title Retroreflector arrays for better light collection efficiency of gamma-ray imaging detectors with continuous scintillation crystals without DOI misestimation Type Journal Article
Year 2014 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 9 Issue Pages P04009 - 14pp
Keywords Gamma detectors (scintillators, CZT, HPG, HgI etc); Interaction of radiation with matter; Gamma camera, SPECT, PET PET/CT, coronary CT angiography (CTA); Detector design and construction technologies and materials
Abstract A method to improve light collection efficiency of gamma-ray imaging detectors by using retroreflector arrays has been tested, simulations of the behaviour of the scintillation light illuminating the retroreflector surface have been made. Measurements including retroreflector arrays in the setup have also been taken. For the measurements, positron emission tomography (PET) detectors with continuous scintillation crystals have been used. Each detector module consists of a continuous LSO-scintillator of dimensions 49x49x10 mm(3) and a H8500 position-sensitive photo-multiplier (PSPMT) from Hamamatsu. By using a continuous scintillation crystal, the scintillation light distribution has not been destroyed and the energy, the centroids along the x- and y-direction and the depth of interaction (DOI) can be estimated. Simulations have also been run taking into account the use of continuous scintillation crystals. Due to the geometry of the continuous scintillation crystals in comparison with pixelated crystals, a good light collection efficiency is necessary to correctly reconstruct the impact point of the gamma-ray. The aim of this study is to investigate whether micro-machine retro-reflectors improve light yield without misestimation of the impact point. The results shows an improvement on the energy and centroid resolutions without worsening the depth of interaction resolution. Therefore it can be concluded that using retroreflector arrays at the entrance side of the scintillation crystal improves light collection efficiency without worsening the impact point estimation.
Address [Ros, A.] Inst Fis Corpuscular IFIC, Valencia 46980, Spain, Email: anrogar2@i3m.upv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume (down) Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:000336123800049 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 1798
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Author Sobczyk, J.E.; Nieves, J.; Sanchez, F.
Title Exclusive-final-state hadron observables from neutrino-nucleus multinucleon knockout Type Journal Article
Year 2020 Publication Physical Review C Abbreviated Journal Phys. Rev. C
Volume 102 Issue 2 Pages 024601 - 16pp
Keywords
Abstract We present results of an updated calculation of the two particle two hole (2p2h) contribution to the neutrino-induced charge-current cross section. We provide also some exclusive observables, interesting from the point of view of experimental studies, e.g., distributions of momenta of the outgoing nucleons and of available energy, which we compare with the results obtained within the NEUT generator. We also compute, and separate from the total, the contributions of 3p3h mechanisms. Finally, we discuss the differences between the present results and previous implementations of the model in MC event generators, done at the level of inclusive cross sections, which might significantly influence the experimental analyses, particularly in the cases where the hadronic observables are considered.
Address [Sobczyk, J. E.; Nieves, J.] Univ Valencia, Inst Fis Corpuscular IFIC, Inst Invest Paterna, Ctr Mixto CSIC, Apartado 22085, E-46071 Valencia, Spain
Corporate Author Thesis
Publisher Amer Physical Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume (down) Series Issue Edition
ISSN 0556-2813 ISBN Medium
Area Expedition Conference
Notes WOS:000555591600002 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4487
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Author Bourguille, B.; Nieves, J.; Sanchez, F.
Title Inclusive and exclusive neutrino-nucleus cross sections and the reconstruction of the interaction kinematics Type Journal Article
Year 2021 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.
Volume 04 Issue 4 Pages 004 - 42pp
Keywords Phenomenological Models
Abstract We present a full kinematic analysis of neutrino-nucleus charged current quasielastic interactions based on the Local Fermi Gas model and the Random Phase Approximation. The model was implemented in the NEUT Monte Carlo framework, which allows us to investigate potentially measurable observables, including hadron distributions. We compare the predictions simultaneously to the most recent T2K and MINERvA charged current (CC) inclusive, CC0 pi and transverse kinematic-imbalance variable results. We pursuit a microscopic interpretation of the relevant reaction mechanisms, with the aim to achieving in neutrino oscillation experiments a correct reconstruction of the incoming neutrino kinematics, free of conceptual biasses. Such study is of the utmost importance for the ambitious experimental program which is underway to precisely determine neutrino properties, test the three-generation paradigm, establish the order of mass eigenstates and investigate leptonic CP violation.
Address [Bourguille, B.] Univ Autonoma Barcelona, Inst Fis Altes Energies IFAE, Barcelona Inst Sci & Technol, Edifici Cn, Bellaterra, Barcelona, Spain, Email: bruno.bourguille@free.fr;
Corporate Author Thesis
Publisher Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume (down) Series Issue Edition
ISSN 1029-8479 ISBN Medium
Area Expedition Conference
Notes WOS:000636427400001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4774
Permanent link to this record