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Author |
Cabello, J.; Etxebeste, A.; Llosa, G.; Ziegler, S.I. |
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Title |
Simulation study of PET detector limitations using continuous crystals |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
60 |
Issue |
9 |
Pages |
3673-3694 |
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Keywords |
continuous crystals; parallax effects; depth of interaction; high resolution; small animal PET |
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Abstract |
Continuous crystals can potentially obtain better intrinsic detector spatial resolution compared to pixelated crystals, additionally providing depth of interaction (DoI) information from the light distribution. To achieve high performance sophisticated interaction position estimation algorithms are required. There are a number of algorithms in the literature applied to different crystal dimensions and different photodetectors. However, the different crystal properties and photodetector array geometries have an impact on the algorithm performance. In this work we analysed, through Monte Carlo simulations, different combinations of realistic crystals and photodetector parameters to better understand their influence on the interaction position estimation accuracy, with special emphasis on the DoI. We used an interaction position estimation based on an analytical model for the present work. Different photodetector granulation schemes were investigated. The impact of the number of crystal faces readout by photodetectors was studied by simulating scenarios with one and two photodetectors. In addition, crystals with different levels of reflection and aspect ratios (AR) were analysed. Results showed that the impact of photodetector granularity is mainly shown near the edges and specially in the corners of the crystal. The resulting intrinsic spatial resolution near the centre with a 12 x 12 x 10 mm(3) LYSO crystal was 0.7-0.9 mm, while the average spatial resolution calculated on the entire crystal was 0.77 +/- 0.18 mm for all the simulated geometries with one and two photodetectors. Having front and back photodetectors reduced the DoI bias (Euclidean distance between estimated DoI and real DoI) and improved the transversal resolution near the corners. In scenarios with one photodetector, small AR resulted in DoI inaccuracies for absorbed events at the entrance of the crystal. These inaccuracies were slightly reduced either by increasing the AR or reducing the amount of reflected light, and highly mitigated using two photodetectors. Using one photodetector, we obtained a piecewise DoI error model with a DoI resolution of 0.4-0.9 mm for a 1.2 AR crystal, and we observed that including a second photodetector or reducing the amount of reflections reduced the DoI bias but did not significantly improve the DoI resolution. Translating the piecewise DoI error model obtained in this study to image reconstruction we obtained a spatial resolution variability of 0.39 mm using 85% of the FoV, compared to 2.59 mm and 1.87 mm without DoI correction or with a dual layer system, respectively. |
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Address |
[Cabello, Jorge; Ziegler, Sibylle I.] Tech Univ Munich, Klinikum Rechts Isar, Nukl Med Klin & Poliklin, D-80290 Munich, Germany, Email: jorge.cabello@tum.de |
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Publisher |
Iop Publishing Ltd |
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English |
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Series Volume  |
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Series Issue |
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ISSN |
0031-9155 |
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Expedition |
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Conference |
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Notes |
WOS:000354104700019 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2226 |
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Author |
Torres-Espallardo, I.; Diblen, F.; Rohling, H.; Solevi, P.; Gillam, J.; Watts, D.; Espana, S.; Vandenberghe, S.; Fiedler, F.; Rafecas, M. |
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Title |
Evaluation of resistive-plate-chamber-based TOF-PET applied to in-beam particle therapy monitoring |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
60 |
Issue |
9 |
Pages |
N187-N208 |
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Keywords |
PET; in-beam; RPC; particle therapy; TOF; range deviation; partial-ring |
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Abstract |
Particle therapy is a highly conformal radiotherapy technique which reduces the dose deposited to the surrounding normal tissues. In order to fully exploit its advantages, treatment monitoring is necessary to minimize uncertainties related to the dose delivery. Up to now, the only clinically feasible technique for the monitoring of therapeutic irradiation with particle beams is Positron Emission Tomography (PET). In this work we have compared a Resistive Plate Chamber (RPC)-based PET scanner with a scintillation-crystal-based PET scanner for this application. In general, the main advantages of the RPC-PET system are its excellent timing resolution, low cost, and the possibility of building large area systems. We simulated a partial-ring scannerbeam monitoring, which has an intrinsically low positron yield compared to diagnostic PET. In addition, for in-beam PET there is a further data loss due to the partial ring configuration. In order to improve the performance of the RPC-based scanner, an improved version of the RPC detector (modifying the thickness of the gas and glass layers), providing a larger sensitivity, has been simulated and compared with an axially extended version of the crystal-based device. The improved version of the RPC shows better performance than the prototype, but the extended version of the crystal-based PET outperforms all other options. based on an RPC prototype under construction within the Fondazione per Adroterapia Oncologica (TERA). For comparison with the crystal-based PET scanner we have chosen the geometry of a commercially available PET scanner, the Philips Gemini TF. The coincidence time resolution used in the simulations takes into account the current achievable values as well as expected improvements of both technologies. Several scenarios (including patient data) have been simulated to evaluate the performance of different scanners. Initial results have shown that the low sensitivity of the RPC hampers its application to hadron |
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Address |
[Torres-Espallardo, I.; Solevi, P.; Gillam, J.; Rafecas, M.] UV, CSIC, Inst Fis Corpuscular IFIC, E-46071 Valencia, Spain, Email: irene.torres@uv.es |
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Publisher |
Iop Publishing Ltd |
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Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000354104700003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2227 |
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Author |
LHCb Collaboration (Aaij, R. et al); Martinez-Vidal, F.; Oyanguren, A.; Ruiz Valls, P.; Sanchez Mayordomo, C. |
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Title |
First observation and amplitude analysis of the B- -> D+K-pi(-) decay |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
91 |
Issue |
9 |
Pages |
092002 - 24pp |
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Keywords |
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Abstract |
The B- -> D+K-pi(-) decay is observed in a data sample corresponding to 3.0 fb(-1) of pp collision data recorded by the LHCb experiment during 2011 and 2012. Its branching fraction is measured to be B(B- -> D+K-pi(-)) = (7.31 +/- 0.19 +/- 0.22 +/- 0.39) x 10(-5) where the uncertainties are statistical, systematic and from the branching fraction of the normalization channel B- -> D+pi(-)pi(-), respectively. An amplitude analysis of the resonant structure of the B- -> D+K-pi(-) decay is used to measure the contributions from quasi-two-body B- -> D-0* (2400)K-0(-), B- -> D-2* (2460)K-0(-), and B- -> D-J* (2760)K-0(-) decays, as well as from nonresonant sources. The D-J* (2760)(0) resonance is determined to have spin 1. |
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Address |
[Bediaga, I.; De Miranda, J. M.; Rodrigues, F. Ferreira; Gomes, A.; Massafferri, A.; Osorio Rodrigues, B.; dos Reis, A. C.; Rodrigues, A. B.] Ctr Brasileiro Pesquisas Fis, Rio De Janeiro, Brazil |
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Publisher |
Amer Physical Soc |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1550-7998 |
ISBN |
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Conference |
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Notes |
WOS:000353881200002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2228 |
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Author |
Liang, W.H.; Molina, R.; Xie, J.J.; Doring, M.; Oset, E. |
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Title |
Predictions for the X(YZ) and X(YZ) with X(4160), Y(3940), Z(3930) |
Type |
Journal Article |
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Year |
2015 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
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Volume |
51 |
Issue |
5 |
Pages |
58 - 7pp |
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Keywords |
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Abstract |
We investigate the decay of and with R being the , , resonances. Under the assumption that these states are dynamically generated from the vector-vector interaction, as has been concluded from several theoretical studies, we use a reaction mechanism of quark production at the elementary level, followed by hadronization of one final pair into two vectors and posterior final state interaction of this pair of vector mesons to produce the resonances. With this procedure we are able to predict five ratios for these decays, which are closely linked to the dynamical nature of these states, and also predict the order of magnitude of the branching ratios which we find of the order of , well within the present measurable range. In order to further test the dynamical nature of these resonances we study the and decays close to the and thresholds and make predictions for the ratio of the mass distributions in these decays and the decay widths. The measurement of these decays rates can help unravel the nature of these resonances. |
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Address |
[Liang, Wei-Hong] Guangxi Normal Univ, Dept Phys, Guilin 541004, Peoples R China, Email: liangwh@mailbox.gxnu.edu.cn |
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Corporate Author |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6001 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000354721100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2229 |
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Author |
LHCb Collaboration (Aaij, R. et al); Martinez-Vidal, F.; Oyanguren, A.; Ruiz Valls, P.; Sanchez Mayordomo, C. |
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Title |
Determination of the branching fractions of B-s(0) -> D-s(-/+) K-/+ and B-0 -> Ds-K+ |
Type |
Journal Article |
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Year |
2015 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
05 |
Issue |
5 |
Pages |
019 - 16pp |
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Keywords |
Hadron-Hadron Scattering; Branching fraction; B physics; Flavor physics |
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Abstract |
Measurements are presented of the branching fractions of the decays B-s(0) -> D-s(-/+) K--/+ and B-0 -> Ds-K+ relative to the decays B-s(0) -> D-s(-)pi(+) and B-0 -> D-s(-)pi(+), respectively. The data used correspond to an integrated luminosity of 3.0 fb(-1) of proton-proton collisions. The ratios of branching fractions are B(B-s(0) -> D-s(-/+) K--/+)/B(B-s(0) -> D-s(-)pi(+)) = 0.0752 +/- 0.0015 +/- 0.0019 and B(B-0 -> Ds-K+)/B(B-0 -> D-pi(+)) = 0.0129 +/- 0.0005 +/- 0.0008, where the uncertainties are statistical and systematic, respectively. |
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Address |
[Bediaga, I.; De Miranda, J. M.; Rodrigues, F. Ferreira; Gomes, A.; Massafferri, A.; Rodrigues, B. Osorio; dos Reis, A. C.; Rodrigues, A. B.] Ctr Brasileiro Pesquisas Fis, Rio De Janeiro, Brazil |
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Corporate Author |
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Thesis |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1029-8479 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000354392500001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2230 |
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| Permanent link to this record |
