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Author Yue, Z. et al; Algora, A.; Nacher, E.
Title Magnetic moments of thallium isotopes in the vicinity of magic N=126 Type Journal Article
Year 2024 Publication Physics Letters B Abbreviated Journal Phys. Lett. B
Volume 849 Issue Pages 138452 - 7pp
Keywords Laser spectroscopy; Hyperfine structure; Magnetic dipole moments; Theory of finite Fermi systems
Abstract The magnetic dipole moments (mu) of Tl-209(g)(N =128) and Tl-207(m)(N = 126) have been measured for the first time using the in -source laser resonance -ionization spectroscopy technique with the Laser Ion Source and Trap (LIST) at ISOLDE (CERN). The application of the LIST suppresses the usually overwhelming background of the isobaric francium isotopes and allows access to heavy thallium isotopes with >207. The self -consistent theory of finite Fermi systems based on the energy density functional by Fayans et al. well describes the N dependence of μfor 1/2(+) thallium ground states, as well as μfor the 11/2(-) isomeric states in europium, gold and thallium isotopes. The inclusion of particle-vibration coupling leads to a better agreement between the theory and experiment for mu(Tl-g , I-pi = 1/2(+)). It is shown that beyond mean-field contributions tocannot be neglected at least for thallium isotopes with I-pi = 1/2(+).
Address [Yue, Z.; Andreyev, A. N.; Cubiss, J. G.] Univ York, Sch Phys Engn & Technol, York YO10 5DD, England, Email: zixuan.yue@cern.ch
Corporate Author Thesis
Publisher Elsevier Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue (down) Edition
ISSN 0370-2693 ISBN Medium
Area Expedition Conference
Notes WOS:001180137800001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5979
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Author Baeza-Ballesteros, J.; Bijnens, J.; Husek, T.; Romero-Lopez, F.; Sharpe, S.R.; Sjo, M.
Title The three-pion K-matrix at NLO in ChPT Type Journal Article
Year 2024 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.
Volume 03 Issue 3 Pages 048 - 43pp
Keywords Chiral Lagrangian; Hadronic Spectroscopy; Structure and Interactions; Lattice QCD
Abstract The three-particle K-matrix, K-df,K-3, is a scheme-dependent quantity that parametrizes short-range three-particle interactions in the relativistic-field-theory three-particle finite-volume formalism. In this work, we compute its value for systems of three pions in all isospin channels through next-to-leading order in Chiral Perturbation Theory, generalizing previous work done at maximum isospin. We obtain analytic expressions through quadratic order (or cubic order, in the case of zero isospin) in the expansion about the three-pion threshold.
Address [Baeza-Ballesteros, Jorge] Univ Valencia, IFIC, CSIC, Paterna 46980, Spain, Email: jorge.baeza@ific.uv.es;
Corporate Author Thesis
Publisher Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue (down) Edition
ISSN 1029-8479 ISBN Medium
Area Expedition Conference
Notes WOS:001178200000005 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 6006
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Author Di Gregorio, E.; Staelens, M.; Hosseinkhah, N.; Karimpoor, M.; Liburd, J.; Lim, L.; Shankar, K.; Tuszynski, J.A.
Title Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer's and Other Neurodegenerative Diseases Type Journal Article
Year 2024 Publication Nanomaterials Abbreviated Journal Nanomaterials
Volume 14 Issue 13 Pages 1093 - 21pp
Keywords proteins; protein dynamics; protein structure; non-invasive therapies; low-level laser therapy; spectroscopy; amide bands; amide I; spectral decomposition
Abstract In small clinical studies, the application of transcranial photobiomodulation (PBM), which typically delivers low-intensity near-infrared (NIR) to treat the brain, has led to some remarkable results in the treatment of dementia and several neurodegenerative diseases. However, despite the extensive literature detailing the mechanisms of action underlying PBM outcomes, the specific mechanisms affecting neurodegenerative diseases are not entirely clear. While large clinical trials are warranted to validate these findings, evidence of the mechanisms can explain and thus provide credible support for PBM as a potential treatment for these diseases. Tubulin and its polymerized state of microtubules have been known to play important roles in the pathology of Alzheimer's and other neurodegenerative diseases. Thus, we investigated the effects of PBM on these cellular structures in the quest for insights into the underlying therapeutic mechanisms. In this study, we employed a Raman spectroscopic analysis of the amide I band of polymerized samples of tubulin exposed to pulsed low-intensity NIR radiation (810 nm, 10 Hz, 22.5 J/cm2 dose). Peaks in the Raman fingerprint region (300-1900 cm-1)-in particular, in the amide I band (1600-1700 cm-1)-were used to quantify the percentage of protein secondary structures. Under this band, hidden signals of C=O stretching, belonging to different structures, are superimposed, producing a complex signal as a result. An accurate decomposition of the amide I band is therefore required for the reliable analysis of the conformation of proteins, which we achieved through a straightforward method employing a Voigt profile. This approach was validated through secondary structure analyses of unexposed control samples, for which comparisons with other values available in the literature could be conducted. Subsequently, using this validated method, we present novel findings of statistically significant alterations in the secondary structures of polymerized NIR-exposed tubulin, characterized by a notable decrease in alpha-helix content and a concurrent increase in beta-sheets compared to the control samples. This PBM-induced alpha-helix to beta-sheet transition connects to reduced microtubule stability and the introduction of dynamism to allow for the remodeling and, consequently, refreshing of microtubule structures. This newly discovered mechanism could have implications for reducing the risks associated with brain aging, including neurodegenerative diseases like Alzheimer's disease, through the introduction of an intervention following this transition.
Address [Di Gregorio, Elisabetta; Staelens, Michael; Tuszynski, Jack A.] Univ Alberta, Fac Sci, Dept Phys, Edmonton, AB T6G 2E1, Canada, Email: michael.staelens@ific.uv.es
Corporate Author Thesis
Publisher Mdpi Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue (down) Edition
ISSN ISBN Medium
Area Expedition Conference
Notes WOS:001269841000001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 6204
Permanent link to this record