Records |
Author |
Sanjuan, R.; Nebot, M.; Chirico, N.; Mansky, L.M.; Belshaw, R. |
Title |
Viral Mutation Rates |
Type |
Journal Article |
Year |
2010 |
Publication |
Journal of Virology |
Abbreviated Journal |
J. Virol. |
Volume |
84 |
Issue |
19 |
Pages |
9733-9748 |
Keywords |
|
Abstract |
Accurate estimates of virus mutation rates are important to understand the evolution of the viruses and to combat them. However, methods of estimation are varied and often complex. Here, we critically review over 40 original studies and establish criteria to facilitate comparative analyses. The mutation rates of 23 viruses are presented as substitutions per nucleotide per cell infection (s/n/c) and corrected for selection bias where necessary, using a new statistical method. The resulting rates range from 10(-8) to 10(-6) s/n/c for DNA viruses and from 10(-6) to 10(-4) s/n/c for RNA viruses. Similar to what has been shown previously for DNA viruses, there appears to be a negative correlation between mutation rate and genome size among RNA viruses, but this result requires further experimental testing. Contrary to some suggestions, the mutation rate of retroviruses is not lower than that of other RNA viruses. We also show that nucleotide substitutions are on average four times more common than insertions/deletions (indels). Finally, we provide estimates of the mutation rate per nucleotide per strand copying, which tends to be lower than that per cell infection because some viruses undergo several rounds of copying per cell, particularly double-stranded DNA viruses. A regularly updated virus mutation rate data set will be available at www.uv.es/rsanjuan/virmut. |
Address |
[Sanjuan, Rafael] Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolutiva, Dept Genet, Valencia 46980, Spain, Email: rafael.sanjuan@uv.es |
Corporate Author |
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Thesis |
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Publisher |
Amer Soc Microbiology |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0022-538x |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000282641800008 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ elepoucu @ |
Serial |
371 |
Permanent link to this record |
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Author |
Aguilar-Saavedra, J.A.; Bernabeu, J. |
Title |
W polarisation beyond helicity fractions in top quark decays |
Type |
Journal Article |
Year |
2010 |
Publication |
Nuclear Physics B |
Abbreviated Journal |
Nucl. Phys. B |
Volume |
840 |
Issue |
1-2 |
Pages |
349-378 |
Keywords |
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Abstract |
We calculate the density matrix for the decay of a polarised top quark into a polarised W boson and a massive 17 quark, for the most general Wth vertex arising from dimension-six gauge-invariant effective operators. We show that, in addition to the well-known W helicity fractions, for polarised top decays it is worth defining and studying the transverse and normal W polarisation fractions, that is, the W polarisation alone two directions orthogonal to its momentum. In particular, a rather simple forward-backward asymmetry in the normal direction is found to be very sensitive to complex phases in one of the Wth anomalous couplings. This asymmetry, which indicates a normal W polarisation, can be generated for example by a P-odd. T-odd transition electric dipole moment. We also investigate the angular distribution of decay products in the top quark rest frame, calculating the spin analysing powers for a general Wth vertex. Finally we show that, using a combined fit to top decay observables and the t W cross section, at LHC it will be possible to obtain model-independent measurements of all the (complex) Wth couplings as well as the single top polarisation. Implications for spin correlations in top pair production are also discussed. |
Address |
[Aguilar-Saavedra, J. A.] Univ Granada, Dept Fis Teor & Cosmos, E-18071 Granada, Spain, Email: jaas@ugr.es |
Corporate Author |
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Thesis |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0550-3213 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000281832900013 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ elepoucu @ |
Serial |
370 |
Permanent link to this record |
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Author |
Taoso, M.; Iocco, F.; Meynet, G.; Bertone, G.; Eggenberger, P. |
Title |
Effect of low mass dark matter particles on the Sun |
Type |
Journal Article |
Year |
2010 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
Volume |
82 |
Issue |
8 |
Pages |
083509 - 14pp |
Keywords |
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Abstract |
We study the effect of dark matter (DM) particles in the Sun, focusing, in particular, on the possible reduction of the solar neutrinos flux due to the energy carried away by DM particles from the innermost regions of the Sun, and to the consequent reduction of the temperature of the solar core. We find that in the very low-mass range between 4 and 10 GeV, recently advocated to explain the findings of the DAMA and CoGent experiments, the effects on neutrino fluxes are detectable only for DM models with a very small, or vanishing, self-annihilation cross section, such as the so-called asymmetric DM models, and we study the combination of DM masses and spin-dependent cross sections which can be excluded with current solar neutrino data. Finally, we revisit the recent claim that DM models with large self-interacting cross sections can lead to a modification of the position of the convective zone, alleviating or solving the solar composition problem. We show that when the "geometric'' upper limit on the capture rate is correctly taken into account, the effects of DM are reduced by orders of magnitude, and the position of the convective zone remains unchanged. |
Address |
[Taoso, Marco] Univ Valencia, CSIC, IFIC, Ed Inst, Valencia 46071, Spain |
Corporate Author |
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Thesis |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1550-7998 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000282680900002 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ elepoucu @ |
Serial |
369 |
Permanent link to this record |
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Author |
BABAR Collaboration (del Amo Sanchez, P. et al); Lopez-March, N.; Martinez-Vidal, F.; Milanes, D.A.; Oyanguren, A. |
Title |
Measurement of CP observables in B-+/- -> DCPK +/- decays and constraints on the CKM angle gamma |
Type |
Journal Article |
Year |
2010 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
Volume |
82 |
Issue |
7 |
Pages |
072004 - 20pp |
Keywords |
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Abstract |
Using the entire sample of 467 x 10(6) Y(4S) -> B (B) over bar decays collected with the BABAR detector at the PEP-II asymmetric-energy B factory at the SLAC National Accelerator Laboratory, we perform an analysis of B-+/- -> DK +/- decays, using decay modes in which the neutral D meson decays to either CP-eigenstates or non-CP-eigenstates. We measure the partial decay rate charge asymmetries for CP-even and CP-odd D final states to be A(CP+) = 0.25 +/- 0.06 +/- 0.02 and A(CP-) = 0.09 +/- 0.07 +/- 0.02, respectively, where the first error is the statistical and the second is the systematic uncertainty. The parameter A(CP+) is different from zero with a significance of 3.6 standard deviations, constituting evidence for direct CP violation. We also measure the ratios of the charged-averaged B partial decay rates in CP and non-CP decays, RCP+ 1.18 +/- 0.09 +/- 0.05 and RCP- = 1.07 +/- 0.08 +/- 0.04. We infer frequentist confidence intervals for the angle gamma of the unitarity triangle, for the strong phase difference delta(B), and for the amplitude ratio r(B), which are related to the B- -> DK- decay amplitude by r(B)e(i(delta B-gamma)) = A(B- -> (D) over bar K-0(-)) = A(B- -> (D) over bar K-0(-))/A(B- -> (DK-)-K-0). Including statistical and systematic uncertainties, we obtain 0: 24 < rB < 0: 45 ( 0: 06 < rB < 0: 51) and, modulo 180 degrees, 11.3 degrees < gamma < 22.7 degrees or 80.8 degrees < gamma < 99.2 degrees or 157.3 degrees < gamma < 168.7 degrees (7.0 degrees < gamma < 173.0 degrees) at the 68% ( 95%) confidence level. |
Address |
[Tico, J. Garra; Grauges, E.] Univ Barcelona, Fac Fis, Dept ECM, E-08028 Barcelona, Spain |
Corporate Author |
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Thesis |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1550-7998 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000282680100001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ elepoucu @ |
Serial |
368 |
Permanent link to this record |
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Author |
de Campos, F.; Eboli, O.J.P.; Hirsch, M.; Magro, M.B.; Porod, W.; Restrepo, D.; Valle, J.W.F. |
Title |
Probing neutrino oscillations in supersymmetric models at the Large Hadron Collider |
Type |
Journal Article |
Year |
2010 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
Volume |
82 |
Issue |
7 |
Pages |
075002 - 8pp |
Keywords |
|
Abstract |
The lightest supersymmetric particle may decay with branching ratios that correlate with neutrino oscillation parameters. In this case the CERN Large Hadron Collider (LHC) has the potential to probe the atmospheric neutrino mixing angle with sensitivity competitive to its low-energy determination by underground experiments. Under realistic detection assumptions, we identify the necessary conditions for the experiments at CERN's LHC to probe the simplest scenario for neutrino masses induced by minimal supergravity with bilinear R parity violation. |
Address |
[de Campos, F.] Univ Estadual Paulista, Dept Quim & Fis, Guaratingueta, SP, Brazil, Email: camposc@feg.unesp.br |
Corporate Author |
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Thesis |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1550-7998 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000282570100004 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ elepoucu @ |
Serial |
367 |
Permanent link to this record |