Abstract: An updated global fit on the parameter-space of the aligned two-Higgs-doublet model is performed with the help of the open-source package HEPfit, assuming the Standard-Model Higgs to be the lightest scalar. No new sources of CP violation, other than the phase in the Cabibbo-Kobayashi-Maskawa matrix of the Standard Model, are considered. A similar global fit was previously performed by O. Eberhardt et al. [Global fits in the aligned two-Higgs-doublet model, J. High Energy Phys. 05 (2021) 005] with a slightly different set of parameters. Our updated fit incorporates improved analyses of the theoretical constraints required for the perturbative unitarity and boundedness of the scalar potential from below, additional flavor observables and updated data on direct searches for heavy scalars at the LHC, Higgs signal strengths, and electroweak precision observables. Although not included in the main fit, the implications of the CDF measurement of the W +/- mass are also discussed.

Abstract: Active galaxies, especially blazars, are among the most promising extragalactic candidates for high-energy neutrino sources. To date, ANTARES searches included these objects and used GeV-TeV gamma-ray flux to select blazars. Here, a statistically complete blazar sample selected by their bright radio emission is used as the target for searches of origins of neutrinos collected by the ANTARES neutrino telescope over 13 yr of operation. The hypothesis of a neutrino-blazar directional correlation is tested by pair counting and a complementary likelihood-based approach. The resulting posttrial p-value is 3.0% (2.2 sigma in the two-sided convention). Additionally, a time-dependent analysis is performed to search for temporal clustering of neutrino candidates as a means of detecting neutrino flares in blazars. None of the investigated sources alone reaches a significant flare detection level. However, the presence of 18 sources with a pretrial significance above 3 sigma indicates a p = 1.4% (2.5 sigma in the two-sided convention) detection of a time-variable neutrino flux. An a posteriori investigation reveals an intriguing temporal coincidence of neutrino, radio, and gamma-ray flares of the J0242+1101 blazar at a p = 0.5% (2.9 sigma in the two-sided convention) level. Altogether, the results presented here suggest a possible connection of neutrino candidates detected by the ANTARES telescope with radio-bright blazars.

Abstract: Light primordial black holes (PBHs) with masses smaller than 10(9) g (10(-24) M-circle dot) evaporate before the onset of Big-Bang nucleosynthesis, rendering their detection rather challenging. If efficiently produced, they may have dominated the universe energy density. We study how such an early matter-dominated era can be probed successfully using gravitational waves (GW) emitted by local and global cosmic strings. While previous studies showed that a matter era generates a single-step suppression of the GW spectrum, we instead find a double-step suppression for local-string GW whose spectral shape provides information on the duration of the matter era. The presence of the two steps in the GW spectrum originates from GW being produced through two events separated in time: loop formation and loop decay, taking place either before or after the matter era. The second step – called the knee – is a novel feature which is universal to any early matter-dominated era and is not only specific to PBHs. Detecting GWs from cosmic strings with LISA, ET, or BBO would set constraints on PBHs with masses between 10(6) and 10(9) g for local strings with tension G μ= 10(-11), and PBHs masses between 10(4) and 10(9) g for global strings with symmetry-breaking scale eta = 10(15) GeV. Effects from the spin of PBHs are discussed.

Abstract: We propose a minimal gauged U(1)(B-L) extension of the minimal supersymmetric Standard Model (MSSM) which resolves the cosmological moduli problem via thermal inflation, and realizes late-time Affleck-Dine leptogensis so as to generate the right amount of baryon asymmetry at the end of thermal inflation. The present relic density of dark matter can be explained by sneutrinos, MSSM neutralinos, axinos, or axions. Cosmic strings from U(1)(B-L) breaking are very thick, and so the expected stochastic gravitational wave background from cosmic string loops has a spectrum different from the one in the conventional Abelian-Higgs model, as would be distinguishable at least at LISA and DECIGO. The characteristic spectrum is due to a flat potential, and may be regarded as a hint of supersymmetry. Combined with the resolution of moduli problem, the expected signal of gravitational waves constrains the U(1)(B-L) breaking scale to be O(10(12-13)) GeV. Interestingly, our model provides a natural possibility for explaining the observed ultra-high-energy cosmic rays thanks to the fact that the core width of strings in our scenario is very large, allowing a large enhancement of particle emissions from the cusps of string loops. Condensation of LHu flat-direction inside of string cores arises inevitably and can also be the main source of the ultra-high-energy cosmic rays accompanied by ultra-high-energy lightest supersymmetric particles.

Abstract: Purpose: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J -PET) scanner for intra-treatment proton beam range monitoring. Methods: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J -PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread -Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J -PET scanner prototype dedicated to the proton beam range assessment. Results: The investigations indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10-5 coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple -layer dual -head geometry. The results indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for the clinical application, Conclusions: We performed simulation studies demonstrating that the feasibility of the J -PET detector for PET -based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre -clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double -layer cylindrical and triple -layer dual -head J -PET geometry configurations seem promising for future clinical application.