| Records |
| Author |
LHCb Collaboration (Aaij, R. et al); Oyanguren, A.; Ruiz Valls, P. |
| Title |
Differential branching fraction and angular analysis of the decay B-0 -> K*(0)mu(+)mu(-) |
Type |
Journal Article |
| Year |
2013 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
| Volume |
08 |
Issue |
8 |
Pages |
131 - 31pp |
| Keywords |
Rare decay; Hadron-Hadron Scattering; B physics; Flavour Changing Neutral Currents; Flavor physics |
| Abstract |
The angular distribution and differential branching fraction of the decay B-0 -> K*(0)mu(+)mu(-) are studied using a data sample, collected by the LHCb experiment in pp collisions at root s = 7 TeV, corresponding to an integrated luminosity of 1.0 fb(-1). Several angular observables are measured in bins of the dimuon invariant mass squared, q(2). A first measurement of the zero-crossing point of the forward-backward asymmetry of the dimuon system is also presented. The zero-crossing point is measured to be q(0)(2) = 4.9 +/- 0.9 GeV2/c(4), where the uncertainty is the sum of statistical and systematic uncertainties. The results are consistent with the Standard Model predictions. |
| Address |
[Bediaga, I.; De Miranda, J. M.; Ferreira Rodrigues, F.; Massafferri, A.; Nasteva, I.; dos Reis, A. C.] Ctr Brasileiro Pesquisas Fis, Rio De Janeiro, Brazil, Email: thomas.blake@cern.ch |
| Corporate Author |
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Thesis |
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Publisher  |
Springer |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1029-8479 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000324114000032 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
1683 |
| Permanent link to this record |
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| Author |
Sanjuan, R.; Nebot, M.; Peris, J.B.; Alcami, J. |
| Title |
Immune Activation Promotes Evolutionary Conservation of T-Cell Epitopes in HIV-1 |
Type |
Journal Article |
| Year |
2013 |
Publication |
Plos Biology |
Abbreviated Journal |
PLoS. Biol. |
| Volume |
11 |
Issue |
4 |
Pages |
e1001523 - 10pp |
| Keywords |
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| Abstract |
The immune system should constitute a strong selective pressure promoting viral genetic diversity and evolution. However, HIV shows lower sequence variability at T-cell epitopes than elsewhere in the genome, in contrast with other human RNA viruses. Here, we propose that epitope conservation is a consequence of the particular interactions established between HIV and the immune system. On one hand, epitope recognition triggers an anti-HIV response mediated by cytotoxic T-lymphocytes (CTLs), but on the other hand, activation of CD4(+) helper T lymphocytes (T-H cells) promotes HIV replication. Mathematical modeling of these opposite selective forces revealed that selection at the intrapatient level can promote either T-cell epitope conservation or escape. We predict greater conservation for epitopes contributing significantly to total immune activation levels (immunodominance), and when T-H cell infection is concomitant to epitope recognition (transinfection). We suggest that HIV-driven immune activation in the lymph nodes during the chronic stage of the disease may offer a favorable scenario for epitope conservation. Our results also support the view that some pathogens draw benefits from the immune response and suggest that vaccination strategies based on conserved T-H epitopes may be counterproductive. |
| Address |
Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolut, Valencia, Spain, Email: rafael.sanjuan@uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Public Library Science |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1545-7885 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000318687800003 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
1446 |
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| Author |
ANTARES Collaboration (Tamburini, C. et al); Aguilar, J.A.; Bigongiari, C.; Dornic, D.; Emanuele, U.; Gomez-Gonzalez, J.P.; Hernandez-Rey, J.J.; Mangano, S.; Ruiz-Rivas, J.; Salesa, F.; Sanchez-Losa, A.; Toscano, S.; Yepes, H.; Zornoza, J.D.; Zuñiga, J. |
| Title |
Deep-Sea Bioluminescence Blooms after Dense Water Formation at the Ocean Surface |
Type |
Journal Article |
| Year |
2013 |
Publication |
Plos One |
Abbreviated Journal |
PLoS One |
| Volume |
8 |
Issue |
7 |
Pages |
e67523 - 10pp |
| Keywords |
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| Abstract |
The deep ocean is the largest and least known ecosystem on Earth. It hosts numerous pelagic organisms, most of which are able to emit light. Here we present a unique data set consisting of a 2.5-year long record of light emission by deep-sea pelagic organisms, measured from December 2007 to June 2010 at the ANTARES underwater neutrino telescope in the deep NW Mediterranean Sea, jointly with synchronous hydrological records. This is the longest continuous time-series of deep-sea bioluminescence ever recorded. Our record reveals several weeks long, seasonal bioluminescence blooms with light intensity up to two orders of magnitude higher than background values, which correlate to changes in the properties of deep waters. Such changes are triggered by the winter cooling and evaporation experienced by the upper ocean layer in the Gulf of Lion that leads to the formation and subsequent sinking of dense water through a process known as “open-sea convection”. It episodically renews the deep water of the study area and conveys fresh organic matter that fuels the deep ecosystems. Luminous bacteria most likely are the main contributors to the observed deep-sea bioluminescence blooms. Our observations demonstrate a consistent and rapid connection between deep open-sea convection and bathypelagic biological activity, as expressed by bioluminescence. In a setting where dense water formation events are likely to decline under global warming scenarios enhancing ocean stratification, in situ observatories become essential as environmental sentinels for the monitoring and understanding of deep-sea ecosystem shifts. |
| Address |
[Tamburini, Christian; Lefevre, Dominique; Martini, Verine; Robert, Anne; Dekeyser, Ivan; Fuda, Jean-Luc] Aix Marseille Univ, CNRS INSU, IRD, MIO,U110, Marseille, France, Email: christian.tamburini@univ-amu.fr; |
| Corporate Author |
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Thesis |
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| Publisher |
Public Library Science |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1932-6203 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000321765300012 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
1496 |
| Permanent link to this record |
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| Author |
Vijande, J.; Granero, D.; Perez-Calatayud, J.; Ballester, F. |
| Title |
Monte Carlo dosimetric study of the medium dose rate CSM40 source |
Type |
Journal Article |
| Year |
2013 |
Publication |
Applied Radiation and Isotopes |
Abbreviated Journal |
Appl. Radiat. Isot. |
| Volume |
82 |
Issue |
|
Pages |
283-288 |
| Keywords |
Brachytherapy; Cs-137 seed; TG-43 based dosimetry; Monte Carlo |
| Abstract |
The Cs-137 medium dose rate (MDR) CSM40 source model (Eckert & Ziegler BEBIG, Germany) is in clinical use but no dosimetric dataset has been published. This study aims to obtain dosimetric data for the CSM40 source for its use in clinical practice as required by the American Association of Physicists in Medicine (AAPM) and the European Society for Radiotherapy and Oncology (ESTRO). Penelope2008 and Geant4 Monte Carlo codes were used to characterize this source dosimetrically. It was located in an unbounded water phantom with composition and mass density as recommended by AAPM and ESTRO. Due to the low photon energies of Cs-137, absorbed dose was approximated by collisional kerma. Additional simulations were performed to obtain the air-kerma strength, sic. Mass-energy absorption coefficients in water and air were consistently derived and used to calculate collisional kerma. Results performed with both radiation transport codes showed agreement typically within 0.05%. Dose rate constant, radial dose function and anisotropy function are provided for the CSM40 and compared with published data for other commercially available Cs-137 sources. An uncertainty analysis has been performed. The data provided by this study can be used as input data and verification in the treatment planning systems. (C) 2013 Elsevier Ltd. All rights reserved. |
| Address |
[Vijande, J.; Ballester, F.] Univ Valencia, Dept Atom Mol & Nucl Phys, E-46100 Burjassot, Spain, Email: Javier.vijande@uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Pergamon-Elsevier Science Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0969-8043 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000328804000043 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
1678 |
| Permanent link to this record |
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| Author |
Villaescusa-Navarro, F.; Vogelsberger, M.; Viel, M.; Loeb, A. |
| Title |
Neutrino signatures on the high-transmission regions of the Lyman alpha forest |
Type |
Journal Article |
| Year |
2013 |
Publication |
Monthly Notices of the Royal Astronomical Society |
Abbreviated Journal |
Mon. Not. Roy. Astron. Soc. |
| Volume |
431 |
Issue |
4 |
Pages |
3670-3677 |
| Keywords |
neutrinos; intergalactic medium; quasars: absorption lines; cosmology: theory; large-scale structure of Universe |
| Abstract |
We quantify the impact of massive neutrinos on the statistics of low-density regions in the intergalactic medium as probed by the Lyman alpha forest at redshifts z = 2.2-4. Based on mock but realistic quasar (QSO) spectra extracted from hydrodynamic simulations with cold dark matter, baryons and neutrinos, we find that the probability distribution of weak Lyman alpha absorption features, as sampled by Lyman alpha flux regions at high transmissivity, is strongly affected by the presence of massive neutrinos. We show that systematic errors affecting the Lyman alpha forest reduce but do not erase the neutrino signal. Using the Fisher matrix formalism, we conclude that the sum of the neutrino masses can be measured, using the method proposed in this paper, with a precision smaller than 0.4 eV using a catalogue of 200 high-resolution (signal-to-noise ratio similar to 100) QSO spectra. This number reduces to 0.27 eV by making use of reasonable priors in the other parameters that also affect the statistics of the high-transitivity regions of the Lyman alpha forest. The constraints obtained with this method can be combined with independent bounds from the cosmic microwave background, large-scale structures and measurements of the matter power spectrum from the Lyman alpha forest to produce tighter upper limits on the sum of the masses of the neutrinos. |
| Address |
Univ Valencia, IFIC, CSIC, E-46071 Valencia, Spain, Email: viel@oats.inaf.it |
| Corporate Author |
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Thesis |
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| Publisher |
Oxford Univ Press |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0035-8711 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000319479000057 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
1458 |
| Permanent link to this record |
