| Records |
| Author |
Koolen, B.B.; Vidal-Sicart, S.; Benlloch, J.M.; Olmos, R.A.V. |
| Title |
Evaluating heterogeneity of primary tumor 18 F-FDG uptake in breast cancer with a dedicated breast PET ( MAMMI): a feasibility study based on correlation with PET/CT |
Type |
Journal Article |
| Year |
2014 |
Publication |
Nuclear Medicine Communications |
Abbreviated Journal |
Nucl. Med. Commun. |
| Volume |
35 |
Issue |
5 |
Pages |
446-452 |
| Keywords |
breast cancer; F-18-FDG; heterogeneity; MAMMI; PET |
| Abstract |
PurposeThe aim of the study was to evaluate the heterogeneity of primary tumor F-18-fluorodeoxyglucose (F-18-FDG) uptake in breast cancer patients using a dedicated breast PET.Patients and methodsA positron emission tomography/computed tomography (PET/CT) of the thorax was performed 60 min after administration of 180-240 MBq of F-18-FDG in patients with breast cancer. Subsequently, 110 min after injection, a scan was taken with a dedicated high-resolution breast PET [MAMmography with Molecular Imaging (MAMMI)]. Both procedures were performed with the patients in the prone position. Four-point scores were used to compare the intensity (0: none; 1: mild; 2: moderate; 3: high) and heterogeneity (0: none; 1: mild; 2: moderate; 3: high) of F-18-FDG uptake between PET/CT and MAMMI images.ResultsThirty-five patients in whom the primary tumor was visualized on both scans were included in this analysis. The mean primary tumor size was 35.1 mm (range 10-108 mm). The mean intensity score was similar on both devices (2.4 for PET/CT and 2.3 for MAMMI; P=0.439), but the mean heterogeneity score on MAMMI images was significantly higher (PET/CT 1.9 vs. MAMMI 2.3; P=0.005). MAMMI showed a higher heterogeneity score in 11 (31%) of 35 patients, especially in tumors with moderate or high intensity. Significantly higher heterogeneity scores on both PET/CT and MAMMI were seen in large tumors (P=0.005 and 0.014, respectively) and in tumors with high intensity scores (P=0.012 and P<0.001, respectively).ConclusionHeterogeneous tumor F-18-FDG uptake in breast cancer is frequently observed, particularly in large tumors with intense F-18-FDG uptake. It is more often seen on MAMMI PET than on conventional PET/CT. Although the observed heterogeneity should be proven histopathologically, this finding offers a rationale for F-18-FDG-guided biopsies. |
| Address |
[Koolen, Bas B.; Vidal-Sicart, Sergi; Olmos, Renato A. Valdes] Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Nucl Med, NL-1066 CX Amsterdam, Netherlands, Email: b.koolen@nki.nl |
| Corporate Author |
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Thesis |
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Publisher  |
Lippincott Williams & Wilkins |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0143-3636 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000334103800002 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
1763 |
| Permanent link to this record |
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| Author |
Tain, J.L. et al; Algora, A.; Estevez, E.; Rubio, B.; Valencia, E.; Jordan, D. |
| Title |
Beta Decay Studies of Neutron Rich Nuclei Using Total Absorption Gamma-ray Spectroscopy and Delayed Neutron Measurements |
Type |
Journal Article |
| Year |
2011 |
Publication |
Journal of the Korean Physical Society |
Abbreviated Journal |
J. Korean Phys. Soc. |
| Volume |
59 |
Issue |
2 |
Pages |
1499-1502 |
| Keywords |
Beta decay; Delayed neutron emission; Total absorption gamma-ray spectroscopy; Neutron detectors; Nuclear technology; Nuclear astrophysics |
| Abstract |
A complete characterisation of the beta-decay of neutron-rich nuclei can be obtained from the measurement of beta-delayed gamma rays and, whenever the process is energetically possible, beta-delayed neutrons. The accurate determination of the beta-intensity distribution and the beta-delayed neutron emission probability is of great relevance in the fields of reactor technology and nuclear astrophysics. A programme for combined measurements using the total absorption gamma-ray spectroscopy technique and both neutron counters and neutron time-of-flight spectrometers is presented. |
| Address |
[Tain, JL; Algora, A; Estevez, E; Rubio, B; Valencia, E; Jordan, D] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia 46071, Spain, Email: tain@ific.uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Korean Physical Soc |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0374-4884 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000294080700010 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ elepoucu @ |
Serial |
730 |
| Permanent link to this record |
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| Author |
n_TOF Collaboration (Guerrero, C. et al); Domingo-Pardo, C.; Tain, J.L. |
| Title |
Study of Photon Strength Function of Actinides: the Case of (235)U, (238)Np and (241)Pu |
Type |
Journal Article |
| Year |
2011 |
Publication |
Journal of the Korean Physical Society |
Abbreviated Journal |
J. Korean Phys. Soc. |
| Volume |
59 |
Issue |
2 |
Pages |
1510-1513 |
| Keywords |
Photon/Gamma strength functions; Pygmy; Scissor mode; n_TOF; Total absorption calorimeter; TAC; Neutron capture |
| Abstract |
The decay from excited levels in medium and heavy nuclei can be described in a statistical approach by means of Photon Strength Functions and Level Density distributions. The study of electromagnetic cascades following neutron capture based on the use of high efficiency detectors has been shown to be well suited for probing the properties of the Photon Strength Function of heavy (high level density) and/or radioactive (high background) nuclei. In this work we have investigated for the first time the validity of the recommended PSF of actinides, in particular (235)U, (238)Np and (241)Pu. Our study includes the search for resonance structures in the PSF below S(n) and draws conclusions regarding their existence and their characteristics in terms of energy, width and electromagnetic nature. |
| Address |
[Guerrero, C; Alvarez-Velarde, F; Ano-Ott, DC; Martinez, T; Mendoza, E; Villamarin, D] Ctr Invest Energet Medioambientales & Technol CIE, Madrid, Spain, Email: carlos.guerrero@ciemat.es |
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Thesis |
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| Publisher |
Korean Physical Soc |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0374-4884 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000294080700013 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ elepoucu @ |
Serial |
731 |
| Permanent link to this record |
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| Author |
n_TOF Collaboration (Guerrero, C. et al); Giubrone, G.; Tain, J.L. |
| Title |
Characterization of the New n_TOF Neutron Beam: Fluence, Profile and Resolution |
Type |
Journal Article |
| Year |
2011 |
Publication |
Journal of the Korean Physical Society |
Abbreviated Journal |
J. Korean Phys. Soc. |
| Volume |
59 |
Issue |
2 |
Pages |
1624-1627 |
| Keywords |
n_TOF; Time-of-flight; Neutron beam; Nuclear data; Cross sections |
| Abstract |
After a halt of four years, the nTOF spallation neutron facility at CERN has resumed operation in November 2008 with a new spallation target characterized by an improved safety and engineering design, resulting in a more robust overall performance and efficient cooling. The first measurement during the 2009 run has aimed at the full characterization of the neutron beam. Several detectors, such as calibrated fission chambers, the nTOF Silicon Monitor, a MicroMegas detector with (10)B and (235)U samples, as well as liquid and solid scintillators have been used in order to characterize the properties of the neutron fluence. The spatial profile of the beam has been studied with a specially designed “X-Y” MicroMegas which provided a 2D image of the beam as a function of neutron energy. Both properties have been compared with simulations performed. with the FLUKA code. The characterization of the resolution function is based on results from simulations which have been verified by the study of narrow capture resonances. of (56)Fe, which were measured as part of a new campaign of (n,gamma) measurements on Fe and Ni isotopes. |
| Address |
[Guerrero, C; Becares, V; Cano-Ott, D; Fernandez-Ordonez, M; Gonzalez-Romero, E; Martin-Fuertes, F; Martinez, T; Mendoza, E; Pina, G; Quinones, J; Vlachoudis, V] Ctr Invest Energet Medioambientales & Tecnol, Madrid 28040, Spain, Email: carlos.guerrero@ciemat.es |
| Corporate Author |
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Thesis |
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| Publisher |
Korean Physical Soc |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0374-4884 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000294080700041 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ elepoucu @ |
Serial |
735 |
| Permanent link to this record |
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| Author |
n_TOF Collaboration (Cano-Ott, D. et al); Domingo-Pardo, C.; Tain, J.L. |
| Title |
Neutron Capture Measuremetns on Minor Actinides at the n_TOF Facility at CERN: Past, Present and Future |
Type |
Journal Article |
| Year |
2011 |
Publication |
Journal of the Korean Physical Society |
Abbreviated Journal |
J. Korean Phys. Soc. |
| Volume |
59 |
Issue |
2 |
Pages |
1809-1812 |
| Keywords |
n_TOF; Total Absorption Calorimeter; TAC; Neutron capture; Cross section; Nuclear waste; Transmutation; Generation IV; Accelerator driven system; ADS; Nuclear reactor; Nuclear energy; Nuclear data; Barium fluoride; Actinides; Plutonium; Americium; Uranium |
| Abstract |
The successful development of advanced nuclear systems for sustainable energy production and nuclear waste management depends on high quality nuclear data libraries. Recent sensitivity studies and reports [1-3] have identified the need for substantially improving the accuracy of neutron cross-section data for minor actinides. The n_TOF collaboration has initiated an ambitious experimental program for the measurement of neutron capture cross sections of minor actinides. Two experimental setups have been constructed for this purpose: a Total Absorption Calorimeter (TAC) [4] for measuring neutron capture cross-sections of low-mass and/or radioactive samples and a set of two low neutron sensitivity C(6)D(6) detectors for the less radioactive materials. |
| Address |
[Cano-Ott, D; Alvarez-Velarde, F; Gonzalez-Romero, E; Guerrero, C; Martinez, T; Mendoza, E; Villamarin, D; Vicente, MC] Ctr Invest Energet Medioambientales & Technol CIE, Madrid, Spain, Email: daniel.cano@ciemat.es |
| Corporate Author |
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Thesis |
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| Publisher |
Korean Physical Soc |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0374-4884 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000294080700085 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ elepoucu @ |
Serial |
737 |
| Permanent link to this record |
