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Author LHCb Collaboration (Aaij, R. et al); Oyanguren, A.; Ruiz Valls, P.
Title Differential branching fraction and angular analysis of the decay B-0 -> K*(0)mu(+)mu(-) Type Journal Article
Year 2013 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.
Volume 08 Issue 8 Pages 131 - 31pp
Keywords Rare decay; Hadron-Hadron Scattering; B physics; Flavour Changing Neutral Currents; Flavor physics
Abstract The angular distribution and differential branching fraction of the decay B-0 -> K*(0)mu(+)mu(-) are studied using a data sample, collected by the LHCb experiment in pp collisions at root s = 7 TeV, corresponding to an integrated luminosity of 1.0 fb(-1). Several angular observables are measured in bins of the dimuon invariant mass squared, q(2). A first measurement of the zero-crossing point of the forward-backward asymmetry of the dimuon system is also presented. The zero-crossing point is measured to be q(0)(2) = 4.9 +/- 0.9 GeV2/c(4), where the uncertainty is the sum of statistical and systematic uncertainties. The results are consistent with the Standard Model predictions.
Address [Bediaga, I.; De Miranda, J. M.; Ferreira Rodrigues, F.; Massafferri, A.; Nasteva, I.; dos Reis, A. C.] Ctr Brasileiro Pesquisas Fis, Rio De Janeiro, Brazil, Email: thomas.blake@cern.ch
Corporate Author Thesis
Publisher (down) Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1029-8479 ISBN Medium
Area Expedition Conference
Notes WOS:000324114000032 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1683
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Author Sanjuan, R.; Nebot, M.; Peris, J.B.; Alcami, J.
Title Immune Activation Promotes Evolutionary Conservation of T-Cell Epitopes in HIV-1 Type Journal Article
Year 2013 Publication Plos Biology Abbreviated Journal PLoS. Biol.
Volume 11 Issue 4 Pages e1001523 - 10pp
Keywords
Abstract The immune system should constitute a strong selective pressure promoting viral genetic diversity and evolution. However, HIV shows lower sequence variability at T-cell epitopes than elsewhere in the genome, in contrast with other human RNA viruses. Here, we propose that epitope conservation is a consequence of the particular interactions established between HIV and the immune system. On one hand, epitope recognition triggers an anti-HIV response mediated by cytotoxic T-lymphocytes (CTLs), but on the other hand, activation of CD4(+) helper T lymphocytes (T-H cells) promotes HIV replication. Mathematical modeling of these opposite selective forces revealed that selection at the intrapatient level can promote either T-cell epitope conservation or escape. We predict greater conservation for epitopes contributing significantly to total immune activation levels (immunodominance), and when T-H cell infection is concomitant to epitope recognition (transinfection). We suggest that HIV-driven immune activation in the lymph nodes during the chronic stage of the disease may offer a favorable scenario for epitope conservation. Our results also support the view that some pathogens draw benefits from the immune response and suggest that vaccination strategies based on conserved T-H epitopes may be counterproductive.
Address Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolut, Valencia, Spain, Email: rafael.sanjuan@uv.es
Corporate Author Thesis
Publisher (down) Public Library Science Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1545-7885 ISBN Medium
Area Expedition Conference
Notes WOS:000318687800003 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 1446
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Author ANTARES Collaboration (Tamburini, C. et al); Aguilar, J.A.; Bigongiari, C.; Dornic, D.; Emanuele, U.; Gomez-Gonzalez, J.P.; Hernandez-Rey, J.J.; Mangano, S.; Ruiz-Rivas, J.; Salesa, F.; Sanchez-Losa, A.; Toscano, S.; Yepes, H.; Zornoza, J.D.; Zuñiga, J.
Title Deep-Sea Bioluminescence Blooms after Dense Water Formation at the Ocean Surface Type Journal Article
Year 2013 Publication Plos One Abbreviated Journal PLoS One
Volume 8 Issue 7 Pages e67523 - 10pp
Keywords
Abstract The deep ocean is the largest and least known ecosystem on Earth. It hosts numerous pelagic organisms, most of which are able to emit light. Here we present a unique data set consisting of a 2.5-year long record of light emission by deep-sea pelagic organisms, measured from December 2007 to June 2010 at the ANTARES underwater neutrino telescope in the deep NW Mediterranean Sea, jointly with synchronous hydrological records. This is the longest continuous time-series of deep-sea bioluminescence ever recorded. Our record reveals several weeks long, seasonal bioluminescence blooms with light intensity up to two orders of magnitude higher than background values, which correlate to changes in the properties of deep waters. Such changes are triggered by the winter cooling and evaporation experienced by the upper ocean layer in the Gulf of Lion that leads to the formation and subsequent sinking of dense water through a process known as “open-sea convection”. It episodically renews the deep water of the study area and conveys fresh organic matter that fuels the deep ecosystems. Luminous bacteria most likely are the main contributors to the observed deep-sea bioluminescence blooms. Our observations demonstrate a consistent and rapid connection between deep open-sea convection and bathypelagic biological activity, as expressed by bioluminescence. In a setting where dense water formation events are likely to decline under global warming scenarios enhancing ocean stratification, in situ observatories become essential as environmental sentinels for the monitoring and understanding of deep-sea ecosystem shifts.
Address [Tamburini, Christian; Lefevre, Dominique; Martini, Verine; Robert, Anne; Dekeyser, Ivan; Fuda, Jean-Luc] Aix Marseille Univ, CNRS INSU, IRD, MIO,U110, Marseille, France, Email: christian.tamburini@univ-amu.fr;
Corporate Author Thesis
Publisher (down) Public Library Science Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1932-6203 ISBN Medium
Area Expedition Conference
Notes WOS:000321765300012 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1496
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Author Vijande, J.; Granero, D.; Perez-Calatayud, J.; Ballester, F.
Title Monte Carlo dosimetric study of the medium dose rate CSM40 source Type Journal Article
Year 2013 Publication Applied Radiation and Isotopes Abbreviated Journal Appl. Radiat. Isot.
Volume 82 Issue Pages 283-288
Keywords Brachytherapy; Cs-137 seed; TG-43 based dosimetry; Monte Carlo
Abstract The Cs-137 medium dose rate (MDR) CSM40 source model (Eckert & Ziegler BEBIG, Germany) is in clinical use but no dosimetric dataset has been published. This study aims to obtain dosimetric data for the CSM40 source for its use in clinical practice as required by the American Association of Physicists in Medicine (AAPM) and the European Society for Radiotherapy and Oncology (ESTRO). Penelope2008 and Geant4 Monte Carlo codes were used to characterize this source dosimetrically. It was located in an unbounded water phantom with composition and mass density as recommended by AAPM and ESTRO. Due to the low photon energies of Cs-137, absorbed dose was approximated by collisional kerma. Additional simulations were performed to obtain the air-kerma strength, sic. Mass-energy absorption coefficients in water and air were consistently derived and used to calculate collisional kerma. Results performed with both radiation transport codes showed agreement typically within 0.05%. Dose rate constant, radial dose function and anisotropy function are provided for the CSM40 and compared with published data for other commercially available Cs-137 sources. An uncertainty analysis has been performed. The data provided by this study can be used as input data and verification in the treatment planning systems. (C) 2013 Elsevier Ltd. All rights reserved.
Address [Vijande, J.; Ballester, F.] Univ Valencia, Dept Atom Mol & Nucl Phys, E-46100 Burjassot, Spain, Email: Javier.vijande@uv.es
Corporate Author Thesis
Publisher (down) Pergamon-Elsevier Science Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0969-8043 ISBN Medium
Area Expedition Conference
Notes WOS:000328804000043 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 1678
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Author Villaescusa-Navarro, F.; Vogelsberger, M.; Viel, M.; Loeb, A.
Title Neutrino signatures on the high-transmission regions of the Lyman alpha forest Type Journal Article
Year 2013 Publication Monthly Notices of the Royal Astronomical Society Abbreviated Journal Mon. Not. Roy. Astron. Soc.
Volume 431 Issue 4 Pages 3670-3677
Keywords neutrinos; intergalactic medium; quasars: absorption lines; cosmology: theory; large-scale structure of Universe
Abstract We quantify the impact of massive neutrinos on the statistics of low-density regions in the intergalactic medium as probed by the Lyman alpha forest at redshifts z = 2.2-4. Based on mock but realistic quasar (QSO) spectra extracted from hydrodynamic simulations with cold dark matter, baryons and neutrinos, we find that the probability distribution of weak Lyman alpha absorption features, as sampled by Lyman alpha flux regions at high transmissivity, is strongly affected by the presence of massive neutrinos. We show that systematic errors affecting the Lyman alpha forest reduce but do not erase the neutrino signal. Using the Fisher matrix formalism, we conclude that the sum of the neutrino masses can be measured, using the method proposed in this paper, with a precision smaller than 0.4 eV using a catalogue of 200 high-resolution (signal-to-noise ratio similar to 100) QSO spectra. This number reduces to 0.27 eV by making use of reasonable priors in the other parameters that also affect the statistics of the high-transitivity regions of the Lyman alpha forest. The constraints obtained with this method can be combined with independent bounds from the cosmic microwave background, large-scale structures and measurements of the matter power spectrum from the Lyman alpha forest to produce tighter upper limits on the sum of the masses of the neutrinos.
Address Univ Valencia, IFIC, CSIC, E-46071 Valencia, Spain, Email: viel@oats.inaf.it
Corporate Author Thesis
Publisher (down) Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0035-8711 ISBN Medium
Area Expedition Conference
Notes WOS:000319479000057 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1458
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Author Manera, M.; Scoccimarro, R.; Percival, W.J.; Samushia, L.; McBride, C.K.; Ross, A.J.; Sheth, R.K.; White, M.; Reid, B.A.; Sanchez, A.G.; de Putter, R.; Xu, X.Y.; Berlind, A.A.; Brinkmann, J.; Maraston, C.; Nichol, B.; Montesano, F.; Padmanabhan, N.; Skibba, R.A.; Tojeiro, R.; Weaver, B.A.
Title The clustering of galaxies in the SDSS-III Baryon Oscillation Spectroscopic Survey: a large sample of mock galaxy catalogues Type Journal Article
Year 2013 Publication Monthly Notices of the Royal Astronomical Society Abbreviated Journal Mon. Not. Roy. Astron. Soc.
Volume 428 Issue 2 Pages 1036-1054
Keywords galaxies: haloes; large-scale structure of Universe
Abstract We present a fast method for producing mock galaxy catalogues that can be used to compute the covariance of large-scale clustering measurements and test analysis techniques. Our method populates a second-order Lagrangian perturbation theory (2LPT) matter field, where we calibrate masses of dark matter haloes by detailed comparisons with N-body simulations. We demonstrate that the clustering of haloes is recovered at similar to 10 per cent accuracy. We populate haloes with mock galaxies using a halo occupation distribution (HOD) prescription, which has been calibrated to reproduce the clustering measurements on scales between 30 and 80 h(-1) Mpc. We compare the sample covariance matrix from our mocks with analytic estimates, and discuss differences. We have used this method to make catalogues corresponding to Data Release 9 of the Baryon Oscillation Spectroscopic Survey (BOSS), producing 600 mock catalogues of the 'CMASS' galaxy sample. These mocks have enabled detailed tests of methods and errors, and have formed an integral part of companion analyses of these galaxy data.
Address Univ Portsmouth, Inst Cosmol & Gravitat, Portsmouth PO1 3FX, Hants, England, Email: marc.manera@port.ac.uk
Corporate Author Thesis
Publisher (down) Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0035-8711 ISBN Medium
Area Expedition Conference
Notes WOS:000318229000007 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1471
Permanent link to this record
 

 
Author Vincent, A.C.; Scott, P.; Trampedach, R.
Title Light bosons in the photosphere and the solar abundance problem Type Journal Article
Year 2013 Publication Monthly Notices of the Royal Astronomical Society Abbreviated Journal Mon. Not. Roy. Astron. Soc.
Volume 432 Issue 4 Pages 3332-3339
Keywords elementary particles; line: formation; Sun: abundances; Sun: atmosphere; cosmology: theory
Abstract Spectroscopy is used to measure the elemental abundances in the outer layers of the Sun, whereas helioseismology probes the interior. It is well known that current spectroscopic determinations of the chemical composition are starkly at odds with the metallicity implied by helioseismology. We investigate whether the discrepancy may be due to conversion of photons to a new light boson in the solar photosphere. We examine the impact of particles with axion-like interactions with the photon on the inferred photospheric abundances, showing that resonant axion-photon conversion is not possible in the region of the solar atmosphere in which line formation occurs. Although non-resonant conversion in the line-forming regions can in principle impact derived abundances, constraints from axion-photon conversion experiments rule out the couplings necessary for these effects to be detectable. We show that this extends to hidden photons and chameleons (which would exhibit similar phenomenological behaviour), ruling out known theories of new light bosons as photospheric solutions to the solar abundance problem.
Address [Vincent, A. C.] Univ Valencia, IFIC, CSIC, E-46071 Valencia, Spain, Email: vincent@ific.uv.es
Corporate Author Thesis
Publisher (down) Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0035-8711 ISBN Medium
Area Expedition Conference
Notes WOS:000321053500058 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1481
Permanent link to this record
 

 
Author Verdu-Andres, S.; Amaldi, U.; Faus-Golfe, A.
Title CABOTO, a high-gradient linac for hadrontherapy Type Journal Article
Year 2013 Publication Journal of Radiation Research Abbreviated Journal J. Radiat. Res.
Volume 54 Issue Pages 155-161
Keywords hadrontherapy; high-gradient linac; cyclinac; carbon ion therapy; multipainting
Abstract The field of hadrontherapy has grown rapidly in recent years. At present the therapeutic beam is provided by a cyclotron or a synchrotron, but neither cyclotrons nor synchrotrons present the best performances for hadrontherapy. The new generation of accelerators for hadrontherapy should allow fast active energy modulation and have a high repetition rate, so that moving organs can be appropriately treated in a reasonable time. In addition, a reduction of the dimensions and cost of the accelerators for hadrontherapy would make the acquisition and operation of a hadrontherapy facility more affordable, which would translate into great benefits for the potential hadrontherapy patients. The 'cyclinac', an accelerator concept that combines a cyclotron with a high-frequency linear accelerator (linac), is a fast-cycling machine specifically conceived to allow for fast active energy modulation. The present paper focuses on CABOTO (CArbon BOoster for Therapy in Oncology), a compact, efficient high-frequency linac that can accelerate C6+ ions and H-2 molecules from 150-410 MeV/u in similar to 24 m. The paper presents the latest design of CABOTO and discusses its performances.
Address [Verdu-Andres, Silvia; Amaldi, Ugo] Fdn Tera, I-28100 Novara, Italy, Email: sverdu@bnl.gov
Corporate Author Thesis
Publisher (down) Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0449-3060 ISBN Medium
Area Expedition Conference
Notes WOS:000321463900021 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1506
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Author Roman, F.L.; Abler, D.; Kanellopoulos, V.; Amoros, G.; Davies, J.; Dosanjh, M.; Jena, R.; Kirkby, N.; Peach, K.; Salt, J.
Title Hadron therapy information sharing prototype Type Journal Article
Year 2013 Publication Journal of Radiation Research Abbreviated Journal J. Radiat. Res.
Volume 54 Issue Pages 56-60
Keywords hadron therapy; proton therapy; data federation; web portal; eHealth; cancer informatics
Abstract The European PARTNER project developed a prototypical system for sharing hadron therapy data. This system allows doctors and patients to record and report treatment-related events during and after hadron therapy. It presents doctors and statisticians with an integrated view of adverse events across institutions, using open-source components for data federation, semantics, and analysis. There is a particular emphasis upon semantic consistency, achieved through intelligent, annotated form designs. The system as presented is ready for use in a clinical setting, and amenable to further customization. The essential contribution of the work reported here lies in the novel data integration and reporting methods, as well as the approach to software sustainability achieved through the use of community-supported open-source components.
Address [Roman, Faustin Laurentiu; Abler, Daniel; Kanellopoulos, Vassiliki; Dosanjh, Manjit] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland, Email: faustin.roman@medaustron.at
Corporate Author Thesis
Publisher (down) Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0449-3060 ISBN Medium
Area Expedition Conference
Notes WOS:000321463900008 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1519
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Author Dawson, K.S. et al; de Putter, R.; Mena, O.
Title The Baryon Oscillation Spectroscopic Survey of SDSS-III Type Journal Article
Year 2013 Publication Astronomical Journal Abbreviated Journal Astron. J.
Volume 145 Issue 1 Pages 10 - 41pp
Keywords cosmology: observations; surveys
Abstract The Baryon Oscillation Spectroscopic Survey (BOSS) is designed to measure the scale of baryon acoustic oscillations (BAO) in the clustering of matter over a larger volume than the combined efforts of all previous spectroscopic surveys of large-scale structure. BOSS uses 1.5 million luminous galaxies as faint as i = 19.9 over 10,000 deg(2) to measure BAO to redshifts z < 0.7. Observations of neutral hydrogen in the Ly alpha forest in more than 150,000 quasar spectra (g < 22) will constrain BAO over the redshift range 2.15 < z < 3.5. Early results from BOSS include the first detection of the large-scale three-dimensional clustering of the Ly alpha forest and a strong detection from the Data Release 9 data set of the BAO in the clustering of massive galaxies at an effective redshift z = 0.57. We project that BOSS will yield measurements of the angular diameter distance d(A) to an accuracy of 1.0% at redshifts z = 0.3 and z = 0.57 and measurements of H(z) to 1.8% and 1.7% at the same redshifts. Forecasts for Ly alpha forest constraints predict a measurement of an overall dilation factor that scales the highly degenerate D-A(z) and H-1(z) parameters to an accuracy of 1.9% at z similar to 2.5 when the survey is complete. Here, we provide an overview of the selection of spectroscopic targets, planning of observations, and analysis of data and data quality of BOSS.
Address [Dawson, Kyle S.; Ahn, Christopher P.; Bolton, Adam S.; Brown, Peter J.; Brownstein, Joel R.; Harris, David W.; Montero-Dorta, Antonio D.; Olmstead, Matthew D.; Shu, Yiping; Zheng, Zheng] Univ Utah, Dept Phys & Astron, Salt Lake City, UT 84112 USA, Email: kdawson@astro.utah.edu
Corporate Author Thesis
Publisher (down) Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0004-6256 ISBN Medium
Area Expedition Conference
Notes WOS:000312251100010 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1266
Permanent link to this record