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Author Carrasco-Ribelles, L.A.; Pardo-Mas, J.R.; Tortajada, S.; Saez, C.; Valdivieso, B.; Garcia-Gomez, J.M.
Title Predicting morbidity by local similarities in multi-scale patient trajectories Type Journal Article
Year 2021 Publication Journal of Biomedical Informatics Abbreviated Journal J. Biomed. Inform.
Volume 120 Issue Pages 103837 - 9pp
Keywords Patient trajectory; Risk prediction; Local alignment; Dynamic programming; Diabetes; Cardiovascular disease
Abstract Patient Trajectories (PTs) are a method of representing the temporal evolution of patients. They can include information from different sources and be used in socio-medical or clinical domains. PTs have generally been used to generate and study the most common trajectories in, for instance, the development of a disease. On the other hand, healthcare predictive models generally rely on static snapshots of patient information. Only a few works about prediction in healthcare have been found that use PTs, and therefore benefit from their temporal dimension. All of them, however, have used PTs created from single-source information. Therefore, the use of longitudinal multi-scale data to build PTs and use them to obtain predictions about health conditions is yet to be explored. Our hypothesis is that local similarities on small chunks of PTs can identify similar patients concerning their future morbidities. The objectives of this work are (1) to develop a methodology to identify local similarities between PTs before the occurrence of morbidities to predict these on new query individuals; and (2) to validate this methodology on risk prediction of cardiovascular diseases (CVD) occurrence in patients with diabetes. We have proposed a novel formal definition of PTs based on sequences of longitudinal multi-scale data. Moreover, a dynamic programming methodology to identify local alignments on PTs for predicting future morbidities is proposed. Both the proposed methodology for PT definition and the alignment algorithm are generic to be applied on any clinical domain. We validated this solution for predicting CVD in patients with diabetes and we achieved a precision of 0.33, a recall of 0.72 and a specificity of 0.38. Therefore, the proposed solution in the diabetes use case can result of utmost utility to secondary screening.
Address [Carrasco-Ribelles, Lucia A.; Pardo-Mas, Jose Ramon; Saez, Carlos; Garcia-Gomez, Juan M.] Univ Politecn Valencia, Biomed Data Sci Lab BDSLAB, Inst Tecnol Informat & Comunicac ITACA, Camino Vera S-N, Valencia 46022, Spain, Email: lucarri@etsii.upv.es;
Corporate Author Thesis
Publisher (up) Academic Press Inc Elsevier Science Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1532-0464 ISBN Medium
Area Expedition Conference
Notes WOS:000683527500003 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4934
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Author Fanchiotti, H.; Garcia Canal, C.A.; Mayosky, M.; Veiga, A.; Vento, V.
Title Measuring the Hannay geometric phase Type Journal Article
Year 2022 Publication American Journal of Physics Abbreviated Journal Am. J. Phys.
Volume 90 Issue 6 Pages 430-435
Keywords
Abstract The Hannay geometric phase is the classical analog of the well-known Berry phase. Its most familiar example is the effect of the latitude lambda on the motion of a Foucault pendulum. We describe an electronic network whose behavior is exactly equivalent to that of the pendulum. The circuit can be constructed from off-the-shelf components using two matched transconductance amplifiers that comprise a gyrator to introduce the non-reciprocal behavior needed to mimic the pendulum. One may precisely measure the dependence of the Hannay phase on lambda by circuit simulation and by laboratory measurements on a constructed circuit.
Address [Fanchiotti, H.; Canal, C. A. Garcia] Univ Nacl La Plata, IFLP, CONICET, CC67, RA-1900 La Plata, Argentina
Corporate Author Thesis
Publisher (up) AIP Publishing Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0002-9505 ISBN Medium
Area Expedition Conference
Notes WOS:000804547100009 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5276
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Author Bernabeu, J.; Sabulsky, D.O.; Sanchez, F.; Segarra, A.
Title Neutrino mass and nature through its mediation in atomic clock interference Type Journal Article
Year 2024 Publication AVS Quantum Science Abbreviated Journal AVS Quantum Sci.
Volume 6 Issue 1 Pages 014410 - 8pp
Keywords
Abstract The absolute mass of neutrinos and their nature are presently unknown. Aggregate matter has a coherent weak charge leading to a repulsive interaction mediated by a neutrino pair. The virtual neutrinos are non-relativistic at micron distances, giving a distinct behavior for Dirac versus Majorana mass terms. This effective potential allows for the disentanglement of the Dirac or Majorana nature of the neutrino via magnitude and distance dependence. We propose an experiment to search for this potential based on the concept that the density-dependent interaction of an atomic probe with a material source in one arm of an atomic clock interferometer generates a differential phase. The appropriate geometry of the device is selected using the saturation of the weak potential as a guide. The proposed experiment has the added benefit of being sensitive to gravity at micron distances. A strategy to suppress the competing Casimir-Polder interaction, depending on the electronic structure of the material source, as well as a way to compensate the gravitational interaction in the two arms of the interferometer is discussed.
Address [Bernabeu, Jose; Segarra, Alejandro] Univ Valencia, Dept Theoret Phys, E-46100 Valencia, Spain, Email: jose.bernabeu@uv.es
Corporate Author Thesis
Publisher (up) AIP Publishing Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes WOS:001186930100001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 6118
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Author Conde, D.; Castillo, F.L.; Escobar, C.; García, C.; Garcia Navarro, J.E.; Sanz, V.; Zaldívar, B.; Curto, J.J.; Marsal, S.; Torta, J.M.
Title Forecasting Geomagnetic Storm Disturbances and Their Uncertainties Using Deep Learning Type Journal Article
Year 2023 Publication Space Weather Abbreviated Journal Space Weather
Volume 21 Issue 11 Pages e2023SW003474 - 27pp
Keywords geomagnetic storms; deep learning; forecasting; SYM-H; uncertainties; hyper-parameter optimization
Abstract Severe space weather produced by disturbed conditions on the Sun results in harmful effects both for humans in space and in high-latitude flights, and for technological systems such as spacecraft or communications. Also, geomagnetically induced currents (GICs) flowing on long ground-based conductors, such as power networks, potentially threaten critical infrastructures on Earth. The first step in developing an alarm system against GICs is to forecast them. This is a challenging task given the highly non-linear dependencies of the response of the magnetosphere to these perturbations. In the last few years, modern machine-learning models have shown to be very good at predicting magnetic activity indices. However, such complex models are on the one hand difficult to tune, and on the other hand they are known to bring along potentially large prediction uncertainties which are generally difficult to estimate. In this work we aim at predicting the SYM-H index characterizing geomagnetic storms multiple-hour ahead, using public interplanetary magnetic field (IMF) data from the Sun-Earth L1 Lagrange point and SYM-H data. We implement a type of machine-learning model called long short-term memory (LSTM) network. Our scope is to estimate the prediction uncertainties coming from a deep-learning model in the context of forecasting the SYM-H index. These uncertainties will be essential to set reliable alarm thresholds. The resulting uncertainties turn out to be sizable at the critical stages of the geomagnetic storms. Our methodology includes as well an efficient optimization of important hyper-parameters of the LSTM network and robustness tests.
Address [Conde, D.; Escobar, C.; Garcia, C.; Garcia, J. E.; Sanz, V.; Zaldivar, B.] Univ Valencia, CSIC, Ctr Mixto, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Daniel.Conde@ific.uv.es
Corporate Author Thesis
Publisher (up) Amer Geophysical Union Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes WOS:001104189700001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5804
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Author Schaffter, T. et al; Albiol, F.; Caballero, L.
Title Evaluation of Combined Artificial Intelligence and Radiologist Assessment to Interpret Screening Mammograms Type Journal Article
Year 2020 Publication JAMA Network Open Abbreviated Journal JAMA Netw. Open
Volume 3 Issue 3 Pages e200265 - 15pp
Keywords
Abstract Importance Mammography screening currently relies on subjective human interpretation. Artificial intelligence (AI) advances could be used to increase mammography screening accuracy by reducing missed cancers and false positives. Objective To evaluate whether AI can overcome human mammography interpretation limitations with a rigorous, unbiased evaluation of machine learning algorithms. Design, Setting, and Participants In this diagnostic accuracy study conducted between September 2016 and November 2017, an international, crowdsourced challenge was hosted to foster AI algorithm development focused on interpreting screening mammography. More than 1100 participants comprising 126 teams from 44 countries participated. Analysis began November 18, 2016. Main Outcomes and Measurements Algorithms used images alone (challenge 1) or combined images, previous examinations (if available), and clinical and demographic risk factor data (challenge 2) and output a score that translated to cancer yes/no within 12 months. Algorithm accuracy for breast cancer detection was evaluated using area under the curve and algorithm specificity compared with radiologists' specificity with radiologists' sensitivity set at 85.9% (United States) and 83.9% (Sweden). An ensemble method aggregating top-performing AI algorithms and radiologists' recall assessment was developed and evaluated. Results Overall, 144231 screening mammograms from 85580 US women (952 cancer positive <= 12 months from screening) were used for algorithm training and validation. A second independent validation cohort included 166578 examinations from 68008 Swedish women (780 cancer positive). The top-performing algorithm achieved an area under the curve of 0.858 (United States) and 0.903 (Sweden) and 66.2% (United States) and 81.2% (Sweden) specificity at the radiologists' sensitivity, lower than community-practice radiologists' specificity of 90.5% (United States) and 98.5% (Sweden). Combining top-performing algorithms and US radiologist assessments resulted in a higher area under the curve of 0.942 and achieved a significantly improved specificity (92.0%) at the same sensitivity. Conclusions and Relevance While no single AI algorithm outperformed radiologists, an ensemble of AI algorithms combined with radiologist assessment in a single-reader screening environment improved overall accuracy. This study underscores the potential of using machine learning methods for enhancing mammography screening interpretation. Question How do deep learning algorithms perform compared with radiologists in screening mammography interpretation? Findings In this diagnostic accuracy study using 144231 screening mammograms from 85580 women from the United States and 166578 screening mammograms from 68008 women from Sweden, no single artificial intelligence algorithm outperformed US community radiologist benchmarks; including clinical data and prior mammograms did not improve artificial intelligence performance. However, combining best-performing artificial intelligence algorithms with single-radiologist assessment demonstrated increased specificity. Meaning Integrating artificial intelligence to mammography interpretation in single-radiologist settings could yield significant performance improvements, with the potential to reduce health care system expenditures and address resource scarcity experienced in population-based screening programs. This diagnostic accuracy study evaluates whether artificial intelligence can overcome human mammography interpretation limits with a rigorous, unbiased evaluation of machine learning algorithms.
Address [Schaffter, Thomas; Hoff, Bruce; Yu, Thomas; Neto, Elias Chaibub; Friend, Stephen; Guinney, Justin] Sage Bionetworks, Computat Oncol, Seattle, WA USA, Email: gustavo@us.ibm.com
Corporate Author Thesis
Publisher (up) Amer Medical Assoc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2574-3805 ISBN Medium
Area Expedition Conference
Notes WOS:000519249800002 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4683
Permanent link to this record
 

 
Author Ortega, P.G.; Segovia, J.; Entem, D.R.; Fernandez, F.
Title Canonical description of the new LHCb resonances Type Journal Article
Year 2016 Publication Physical Review D Abbreviated Journal Phys. Rev. D
Volume 94 Issue 11 Pages 114018 - 7pp
Keywords
Abstract The LHCb Collaboration has recently observed four J/psi phi structures called X(4140), X(4274), X(4500), and X(4700) in the B+ -> J/psi phi K+ decays. We study them herein using a nonrelativistic constituent quark model in which the degrees of freedom are quark-antiquark and meson-meson components. The X(4140) resonance appears as a cusp in the J/psi phi channel due to the near coincidence of the D-s(+/-) D-s(*+/-) and J/psi phi mass thresholds. The remaining three [X(4274), X(4500), and X(4700)] appear as conventional charmonium states with quantum numbers 3(3)P(1), 4(3)P(0), and 5(3)P(0), respectively, and their masses and widths are slightly modified due to their coupling with the corresponding closest meson-meson thresholds. A particular feature of our quark model is a lattice-based screened linear confining interaction that has been constrained in the light-quark sector and usually produces higher excited heavy-quark states with lower masses than standard quark model predictions.
Address [Ortega, Pablo G.] Univ Valencia, Ctr Mixto CSIC, Inst Fis Corpuscular IFIC, ES-46071 Valencia, Spain, Email: pgortega@ific.uv.es;
Corporate Author Thesis
Publisher (up) Amer Physical Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2470-0010 ISBN Medium
Area Expedition Conference
Notes WOS:000398727000006 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3039
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Author Miyahara, K.; Hyodo, T.; Oka, M.; Nieves, J.; Oset, E.
Title Theoretical study of the Xi(1620) and Xi(1690) resonances in Xi(c)-> pi(+) MB decays Type Journal Article
Year 2017 Publication Physical Review C Abbreviated Journal Phys. Rev. C
Volume 95 Issue 3 Pages 035212 - 12pp
Keywords
Abstract Nonleptonic weak decays of Xi(c) into pi(+) and a meson (M)-baryon (B) final state, MB, are analyzed from the viewpoint of probing S = -2 baryon resonances, i.e., Xi(1620) and Xi(1690), of which spin-parity and other properties are not well known. We argue that the weak decay of Xi(c) is dominated by a single quark-line diagram, preferred by the Cabibbo-Kobayashi-Maskawa coefficient, color recombination factor, the diquark correlation, and the kinematical condition. The decay process has an advantage of being free from meson resonances in the p+ M invariantmass distribution. The invariant mass distribution of the meson-baryon final state is calculated with three different chiral unitary approaches, assuming that the Xi(1620) and Xi(1690) resonances have J(P) = 1/2(-). It is found that a clear peak for the Xi(1690) is seen in the pi Xi and K Lambda spectra. We also suggest that the ratios of the pi Xi, K Lambda, and K Sigma final states are useful to distinguish whether the peak is originated from the Xi(1690) resonance or it is a K Sigma threshold effect.
Address [Miyahara, Kenta] Kyoto Univ, Grad Sch Sci, Dept Phys, Kyoto 6068502, Japan, Email: miyahara.kenta.62r@st.kyoto-u.ac.jp
Corporate Author Thesis
Publisher (up) Amer Physical Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2469-9985 ISBN Medium
Area Expedition Conference
Notes WOS:000399144100008 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3044
Permanent link to this record
 

 
Author PreSPEC and AGATA Collaborations (Ralet, D. et al); Domingo-Pardo, C.; Gadea, A.; Huyuk, T.
Title Lifetime measurement of neutron-rich even-even molybdenum isotopes Type Journal Article
Year 2017 Publication Physical Review C Abbreviated Journal Phys. Rev. C
Volume 95 Issue 3 Pages 034320 - 11pp
Keywords
Abstract Background: In the neutron-rich A approximate to 100 mass region, rapid shape changes as a function of nucleon number as well as coexistence of prolate, oblate, and triaxial shapes are predicted by various theoretical models. Lifetime measurements of excited levels in the molybdenum isotopes allow the determination of transitional quadrupole moments, which in turn provides structural information regarding the predicted shape change. Purpose: The present paper reports on the experimental setup, the method that allowed one to measure the lifetimes of excited states in even-even molybdenum isotopes from mass A = 100 up to mass A = 108, and the results that were obtained. Method: The isotopes of interest were populated by secondary knock-out reaction of neutron-rich nuclei separated and identified by the GSI fragment separator at relativistic beam energies and detected by the sensitive PreSPEC-AGATA experimental setup. The latter included the Lund-York-Cologne calorimeter for identification, tracking, and velocity measurement of ejectiles, and AGATA, an array of position sensitive segmented HPGe detectors, used to determine the interaction positions of the gamma ray enabling a precise Doppler correction. The lifetimes were determined with a relativistic version of the Doppler-shift-attenuation method using the systematic shift of the energy after Doppler correction of a gamma-ray transition with a known energy. This relativistic Doppler-shift-attenuation method allowed the determination of mean lifetimes from 2 to 250 ps. Results: Even-even molybdenum isotopes from mass A = 100 to A = 108 were studied. The decays of the low-lying states in the ground-state band were observed. In particular, two mean lifetimes were measured for the first time: tau = 29.7(-9.1)(+11.3) ps for the 4(+) state of Mo-108 and tau = 3.2(-0.7)(+ 0.7) ps for the 6(+) state of Mo-102. Conclusions: The reduced transition strengths B(E2), calculated from lifetimes measured in this experiment, compared to beyond-mean-field calculations, indicate a gradual shape transition in the chain of molybdenum isotopes when going from A = 100 to A = 108 with a maximum reached at N = 64. The transition probabilities decrease for Mo-108 which may be related to its well-pronounced triaxial shape indicated by the calculations.
Address [Ralet, D.; Cortes, M. L.; Gregor, E.; Guastalla, G.; Givechev, A.; Habermann, T.; Louchart-Henning, C.; Merchan, E.; Pietralla, N.; Reese, M.; Singh, P. P.; Stahl, C.] Tech Univ Darmstadt, Inst Kernphys, D-64289 Darmstadt, Germany, Email: ralet@csnsm.in2p3.fr
Corporate Author Thesis
Publisher (up) Amer Physical Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2469-9985 ISBN Medium
Area Expedition Conference
Notes WOS:000399143200002 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3045
Permanent link to this record
 

 
Author Bejarano, C.; Olmo, G.J.; Rubiera-Garcia, D.
Title What is a singular black hole beyond general relativity? Type Journal Article
Year 2017 Publication Physical Review D Abbreviated Journal Phys. Rev. D
Volume 95 Issue 6 Pages 064043 - 18pp
Keywords
Abstract Exploring the characterization of singular black hole spacetimes, we study the relation between energy density, curvature invariants, and geodesic completeness using a quadratic f(R) gravity theory coupled to an anisotropic fluid. Working in a metric-affine approach, our models and solutions represent minimal extensions of general relativity (GR) in the sense that they rapidly recover the usual Reissner-Nordstrm solution from near the inner horizon outwards. The anisotropic fluid helps modify only the innermost geometry. Depending on the values and signs of two parameters on the gravitational and matter sectors, a breakdown of the correlations between the finiteness/ divergence of the energy density, the behavior of curvature invariants, and the (in) completeness of geodesics is obtained. We find a variety of configurations with and without wormholes, a case with a de Sitter interior, solutions that mimic nonlinear models of electrodynamics coupled to GR, and configurations with up to four horizons. Our results raise questions regarding what infinities, if any, a quantum version of these theories should regularize.
Address [Bejarano, Cecilia] UBA, CONICET, IAFE, Casilla Correo 67,Sucursal 28, RA-1428 Buenos Aires, DF, Argentina, Email: cbejarano@iafe.uba.ar;
Corporate Author Thesis
Publisher (up) Amer Physical Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2470-0010 ISBN Medium
Area Expedition Conference
Notes WOS:000399146000007 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3046
Permanent link to this record
 

 
Author Richard, J.M.; Valcarce, A.; Vijande, J.
Title String dynamics and metastability of all-heavy tetraquarks Type Journal Article
Year 2017 Publication Physical Review D Abbreviated Journal Phys. Rev. D
Volume 95 Issue 5 Pages 054019 - 7pp
Keywords
Abstract Multiquark states have been advocated to explain recent experimental data in the heavy-light sector, and there are already speculations about multiquarks containing only heavy quarks and antiquarks. With a rigorous treatment of the four-body problem in current quark models, full-charm (cc (c) over bar(c) over bar) and full-beauty(bb (b) over bar(b) over bar) tetraquarks are found to be unbound. Thus their stability should rely on more subtle effects that are not included in the simple picture of constituent quarks. The case of (bc (b) over bar(c) over bar) might be more favorable if the naive color-additive model of confinement is replaced by a string-inspired interaction.
Address [Richard, Jean-Marc] Univ Lyon, UCBL, Inst Phys Nucl Lyon, IN2P3,CNRS, 4 Rue Enrico Fermi, F-69622 Villeurbanne, France, Email: j-m.richard@ipnl.in2p3.fr;
Corporate Author Thesis
Publisher (up) Amer Physical Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2470-0010 ISBN Medium
Area Expedition Conference
Notes WOS:000399144700001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3047
Permanent link to this record