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Author |
Brzezinski, K. et al |
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Title |
Detection of range shifts in proton beam therapy using the J-PET scanner: a patient simulation study |
Type |
Journal Article |
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Year |
2023 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
68 |
Issue |
14 |
Pages |
145016 - 17pp |
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Keywords |
proton therapy; positron emission tomography; in vivo range verification; J-PET; Monte Carlo |
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Abstract |
Objective. The Jagiellonian positron emission tomography (J-PET) technology, based on plastic scintillators, has been proposed as a cost effective tool for detecting range deviations during proton therapy. This study investigates the feasibility of using J-PET for range monitoring by means of a detailed Monte Carlo simulation study of 95 patients who underwent proton therapy at the Cyclotron Centre Bronowice (CCB) in Krakow, Poland. Approach. Discrepancies between prescribed and delivered treatments were artificially introduced in the simulations by means of shifts in patient positioning and in the Hounsfield unit to the relative proton stopping power calibration curve. A dual-layer, cylindrical J-PET geometry was simulated in an in-room monitoring scenario and a triple-layer, dual-head geometry in an in-beam protocol. The distribution of range shifts in reconstructed PET activity was visualized in the beam's eye view. Linear prediction models were constructed from all patients in the cohort, using the mean shift in reconstructed PET activity as a predictor of the mean proton range deviation. Main results. Maps of deviations in the range of reconstructed PET distributions showed agreement with those of deviations in dose range in most patients. The linear prediction model showed a good fit, with coefficient of determination r (2) = 0.84 (in-room) and 0.75 (in-beam). Residual standard error was below 1 mm: 0.33 mm (in-room) and 0.23 mm (in-beam). Significance. The precision of the proposed prediction models shows the sensitivity of the proposed J-PET scanners to shifts in proton range for a wide range of clinical treatment plans. Furthermore, it motivates the use of such models as a tool for predicting proton range deviations and opens up new prospects for investigations into the use of intra-treatment PET images for predicting clinical metrics that aid in the assessment of the quality of delivered treatment. |
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Address |
[Brzezinski, Karol; Gajewski, Jan; Kopec, Renata; Olko, Pawel; Stasica, Paulina; Rucinski, Antoni] Polish Acad Sci, Inst Nucl Phys, Krakow, Poland, Email: karol.brzezinski@ific.uv.es |
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IOP Publishing Ltd |
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English |
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0031-9155 |
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Notes |
WOS:001026535700001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5616 |
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Author |
Bombacigno, F.; Moretti, F.; Boudet, S.; Olmo, G.J. |
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Title |
Landau damping for gravitational waves in parity-violating theories |
Type |
Journal Article |
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Year |
2023 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
02 |
Issue |
2 |
Pages |
009 - 29pp |
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Keywords |
Gravitational waves in GR and beyond: theory; modified gravity; gravitational waves / experiments; dark matter experiments |
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Abstract |
We discuss how tensor polarizations of gravitational waves can suffer Landau damping in the presence of velocity birefringence, when parity symmetry is explicitly broken. In particular, we analyze the role of the Nieh-Yan and Chern-Simons terms in modified theories of gravity, showing how the gravitational perturbation in collisionless media can be characterized by a subluminal phase velocity, circumventing the well-known results of General Relativity and allowing for the appearance of the kinematic damping. We investigate in detail the connection between the thermodynamic properties of the medium, such as temperature and mass of the particles interacting with the gravitational wave, and the parameters ruling the parity violating terms of the models. In this respect, we outline how the dispersion relations can give rise in each model to different regions of the wavenumber space, where the phase velocity is subluminal, superluminal or does not exist. Quantitative estimates on the considered models indicate that the phenomenon of Landau damping is not detectable given the sensitivity of present-day instruments. |
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Address |
[Bombacigno, F.; Moretti, F.; Olmo, Gonzalo J.] Ctr Mixto Univ Valencia, CSIC, Dept Fis Teor, Carrer Doctor Moliner 50, Valencia 46100, Spain, Email: flavio2.bombacigno@uv.es; |
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IOP Publishing Ltd |
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English |
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ISSN |
1475-7516 |
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Notes |
WOS:001040875600002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5624 |
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Author |
Cosme, C.; Figueroa, D.G.; Loayza, N. |
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Title |
Gravitational wave production from preheating with trilinear interactions |
Type |
Journal Article |
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Year |
2023 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
05 |
Issue |
5 |
Pages |
023 - 30pp |
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Keywords |
physics of the early universe; primordial gravitational waves (theory); gravita-tional waves; sources; particle physics-cosmology connection |
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Abstract |
We investigate the production of gravitational waves (GWs) during preheating with monomial/polynomial inflationary potentials, considering a trilinear coupling & phi;x2 between a singlet inflaton & phi; and a daughter scalar field x. For sufficiently large couplings, the trilinear interaction leads to an exponential production of x particles and, as a result, a large stochastic GW background (SGWB) is generated throughout the process. We study the linear and non-linear dynamics of preheating with lattice simulations, following the production of GWs through all relevant stages. We find that large couplings lead to SGWBs with amplitudes today that can reach up to h2 �(0) GW <^> 5 & BULL; 10-9. These backgrounds are however peaked at high frequencies fp > 5 & BULL; 106 Hz, which makes them undetectable by current/planned GW observatories. As the amount of GWs produced is in any case remarkable, we discuss the prospects for probing the SGWB indirectly by using constraints on the effective number of relativistic species in the universe Neff. |
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[Cosme, Catarina; Figueroa, Daniel G.; Loayza, Nicolas] Univ Valencia CSIC, Inst Fis Corpuscular IFIC, Parc Cientif UV,C-Catedrat Jose Beltran 2, E-46980 Paterna, Spain, Email: catarina.cosme@ific.uv.es; |
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Publisher |
IOP Publishing Ltd |
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Language |
English |
Summary Language |
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ISSN |
1475-7516 |
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Notes |
WOS:001038638500007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5660 |
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Author |
Zhai, Y.J.; Giare, W.; van de Bruck, C.; Di Valentino, E.; Mena, O.; Nunes, R.C. |
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Title |
A consistent view of interacting dark energy from multiple CMB probes |
Type |
Journal Article |
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Year |
2023 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
07 |
Issue |
7 |
Pages |
032 - 16pp |
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Keywords |
cosmological parameters from CMBR; dark energy theory |
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Abstract |
We analyze a cosmological model featuring an interaction between dark energy and dark matter in light of the measurements of the Cosmic Microwave Background released by three independent experiments: the most recent data by the Planck satellite and the Atacama Cosmology Telescope, and WMAP (9-year data). We show that different combinations of the datasets provide similar results, always favoring an interacting dark sector with a 95% C.L. significance in the majority of the cases. Remarkably, such a preference remains consistent when cross-checked through independent probes, while always yielding a value of the expansion rate H0 consistent with the local distance ladder measurements. We investigate the source of this preference by scrutinizing the angular power spectra of temperature and polarization anisotropies as measured by different experiments. |
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Address |
[Zhai, Yuejia; Giare, William; van de Bruck, Carsten; Di Valentino, Eleonora] Univ Sheffield, Sch Math & Stat, Hounsfield Rd, Sheffield S3 7RH, England, Email: yzhai13@sheffield.ac.uk; |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Abbreviated Series Title |
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ISSN |
1475-7516 |
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Notes |
WOS:001066525900001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5673 |
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Author |
ANTARES Collaboration (Albert, A. et al); Alves, S.; Calvo, D.; Carretero, V.; Gozzini, R.; Hernandez-Rey, J.J.; Lazo, A.; Manczak, J.; Pieterse, C.; Real, D.; Saina, A.; Sanchez-Losa, A.; Salesa Greus, F.; Zornoza, J.D.; Zuñiga, J. |
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Title |
Review of the online analyses of multi-messenger alerts and electromagnetic transient events with the ANTARES neutrino telescope |
Type |
Journal Article |
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Year |
2023 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
08 |
Issue |
8 |
Pages |
072 - 23pp |
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Keywords |
neutrino astronomy; neutrino detectors |
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Abstract |
By constantly monitoring a very large portion of the sky, neutrino telescopes are well-designed to detect neutrinos emitted by transient astrophysical events. Real-time searches with the ANTARES telescope have been performed to look for neutrino candidates coincident with gamma-ray bursts detected by the Swift and Fermi satellites, high-energy neutrino events registered by IceCube, transient events from blazars monitored by HAWC, photon-neutrino coincidences by AMON notices and gravitational wave candidates observed by LIGO/Virgo. By requiring temporal coincidence, this approach increases the sensitivity and the significance of a potential discovery. This paper summarises the results of the followup performed of the ANTARES telescope between January 2014 and February 2022, which corresponds to the end of the data-taking period. |
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Address |
[Albert, A.; Drouhin, D.; Pradier, T.] Univ Strasbourg, CNRS, IPHC UMR 7178, F-67000 Strasbourg, France, Email: dornic@cppm.in2p3.fr |
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Corporate Author |
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Thesis |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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ISSN |
1475-7516 |
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Conference |
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Notes |
WOS:001068854500001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5703 |
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