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Author |
Otal, A.; Celada, F.; Chimeno, J.; Vijande, J.; Pellejero, S.; Perez-Calatayud, M.J.; Villafranca, E.; Fuentemilla, N.; Blazquez, F.; Rodriguez, S.; Perez-Calatayud, J. |
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Title |
Review on Treatment Planning Systems for Cervix Brachytherapy (Interventional Radiotherapy): Some Desirable and Convenient Practical Aspects to Be Implemented from Radiation Oncologist and Medical Physics Perspectives |
Type |
Journal Article |
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Year |
2022 |
Publication |
Cancers |
Abbreviated Journal |
Cancers |
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Volume |
14 |
Issue |
14 |
Pages |
3467 - 15pp |
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Keywords |
cervix; treatment planning systems; interstitial applicators; magnetic resonance |
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Abstract |
Simple Summary There are no brachytherapy treatment planning systems (TPS) exclusively for the treatment of cervical tumours, so general-purpose TPSs are used. However, these treatments have some particular features concerning the treatment of other pathologies, especially in the case of exclusive use of MRI as an imaging modality and the presence of gynaecological applicators in combination with an interstitial part. That is why it is essential to review the latest versions of commercial TPSs to find the potential features to improve with the help of a group of experimented medical physicists and radiation oncologists. Furthermore, after reviewing the recent literature for advances applicable to cervical brachytherapy and through his own clinical experience, possible improvements are proposed to software providers for the development of new tools. Intracavitary brachytherapy (BT, Interventional Radiotherapy, IRT), plays an essential role in the curative intent of locally advanced cervical cancer, for which the conventional approach involves external beam radiotherapy with concurrent chemotherapy followed by BT. This work aims to review the different methodologies used by commercially available treatment planning systems (TPSs) in exclusive magnetic resonance imaging-based (MRI) cervix BT with interstitial component treatments. Practical aspects and improvements to be implemented into the TPSs are discussed. This review is based on the clinical expertise of a group of radiation oncologists and medical physicists and on interactive demos provided by the software manufacturers. The TPS versions considered include all the new tools currently in development for future commercial releases. The specialists from the supplier companies were asked to propose solutions to some of the challenges often encountered in a clinical environment through a questionnaire. The results include not only such answers but also comments by the authors that, in their opinion, could help solve the challenges covered in these questions. This study summarizes the possibilities offered nowadays by commercial TPSs, highlighting the absence of some useful tools that would notably improve the planning of MR-based interstitial component cervix brachytherapy. |
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Address |
[Otal, Antonio] Hosp Arnau Vilanova, Med Phys Dept, Lleida 25198, Spain, Email: aotalpalacin@gmail.com; |
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Mdpi |
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English |
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WOS:000832057600001 |
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no |
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yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5304 |
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Author |
Sanchis-Lozano, M.A. |
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Title |
Stringy Signals from Large-Angle Correlations in the Cosmic Microwave Background? |
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Journal Article |
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Year |
2022 |
Publication |
Universe |
Abbreviated Journal |
Universe |
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Volume |
8 |
Issue |
8 |
Pages |
396 - 13pp |
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Keywords |
cosmic microwave background; angular correlations; inflation; string theory |
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Abstract |
We interpret the lack of large-angle temperature correlations and the even-odd parity imbalance observed in the cosmic microwave background (CMB) by COBE, WMAP and Planck satellite missions as a possible stringy signal ultimately stemming from a composite inflaton field (e.g., a fermionic condensate). Based on causality arguments and a Fourier analysis of the angular two-point correlation function, two infrared cutoffs k(min)(even,odd) (satisfying k(min)(even) similar or equal to 2k(min)(odd)) are introduced to the CMB power spectrum associated, respectively, with periodic and antiperiodic boundary conditions of the fermionic constituents (echoing the Neveu-Schwarz-Ramond model in superstring theory), without resorting to any particular model. |
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[Sanchis-Lozano, Miguel-Angel] Univ Valencia, Dept Theoret Phys, Doctor Moliner 50, Burjassot 46011, Spain, Email: miguel.angel.sanchis@ific.uv.es |
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Mdpi |
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WOS:000845107300001 |
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no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5344 |
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Author |
Real, D.; Calvo, D.; Diaz, A.; Salesa Greus, F.; Sanchez Losa, A. |
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Title |
A Narrow Optical Pulse Emitter Based on LED: NOPELED |
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Journal Article |
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Year |
2022 |
Publication |
Sensors |
Abbreviated Journal |
Sensors |
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Volume |
22 |
Issue |
19 |
Pages |
7683 - 15pp |
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Keywords |
short optical pulse; optical instrumentation |
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Abstract |
Light sources emitting short pulses are needed in many particle physics experiments using optical sensors as they can replicate the light produced by the particles being detected and are also an important calibration and test element. This work presents NOPELED, a light source based on LEDs emitting short optical pulses with typical rise times of less than 3 ns and Full Width at Half Maximum lower than 7 ns. The emission wavelength depends on the model of LED used. Several LED models have been characterized in the range from 405 to 532 nm, although NOPELED can work with LED emitting wavelengths outside of that region. While the wavelength is fixed for a given LED model, the intensity and the frequency of the optical pulse can be controlled. NOPELED, which also has low cost and simple operation, can be operated remotely, making it appropriate for either different physics experiments needing in-place light sources such as astrophysical neutrino detectors using photo-multipliers or positron emission tomography devices using scintillation counters, or, beyond physics, applications needing short pulses of light such as protein fluorescence or chemodetection of heavy metals. |
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Address |
[Real, Diego; Calvo, David; Salesa Greus, Francisco; Sanchez Losa, Agustin] Univ Valencia, IFIC Inst Fis Corpuscular, CSIC, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: real@ific.uv.es; |
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Mdpi |
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English |
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Notes |
WOS:000867935300001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5381 |
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Author |
Navarro-Salas, J.; Pla, S. |
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Title |
Particle Creation and the Schwinger Model |
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Journal Article |
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Year |
2022 |
Publication |
Symmetry-Basel |
Abbreviated Journal |
Symmetry-Basel |
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Volume |
14 |
Issue |
11 |
Pages |
2435 - 9pp |
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Keywords |
Schwinger model; semiclassical theory; particle creation |
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Abstract |
We study the particle creation process in the Schwinger model coupled with an external classical source. One can approach the problem by taking advantage of the fact that the full quantized model is solvable and equivalent to a (massive) gauge field with a non-local effective action. Alternatively, one can also face the problem by following the standard semiclassical route. This means quantizing the massless Dirac field and considering the electromagnetic field as a classical background. We evaluate the energy created by a generic, homogeneous, and time-dependent source. The results match exactly in both approaches. This proves in a very direct and economical way the validity of the semiclassical approach for the (massless) Schwinger model, in agreement with a previous analysis based on the linear response equation. Our discussion suggests that a similar analysis for the massive Schwinger model could be used as a non-trivial laboratory to confront a fully quantized solvable model with its semiclassical approximation, therefore mimicking the long-standing confrontation of quantum gravity with quantum field theory in curved spacetime. |
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Address |
[Navarro-Salas, Jose] Univ Valencia, Ctr Mixto Univ Valencia CSIC, Fac Fis, Dept Fis Teor & IFIC, Burjassot 46100, Valencia, Spain, Email: jnavarro@ific.uv.es |
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Mdpi |
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English |
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Notes |
WOS:000895122100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5432 |
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Author |
Ramirez-Uribe, S.; Hernandez-Pinto, R.J.; Rodrigo, G.; Sborlini, G.F.R. |
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Title |
From Five-Loop Scattering Amplitudes to Open Trees with the Loop-Tree Duality |
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Journal Article |
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Year |
2022 |
Publication |
Symmetry-Basel |
Abbreviated Journal |
Symmetry-Basel |
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Volume |
14 |
Issue |
12 |
Pages |
2571 - 14pp |
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Keywords |
perturbative QFT; higher-order calculations; multiloop Feynman integrals |
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Abstract |
Characterizing multiloop topologies is an important step towards developing novel methods at high perturbative orders in quantum field theory. In this article, we exploit the Loop-Tree Duality (LTD) formalism to analyse multiloop topologies that appear for the first time at five loops. Explicitly, we open the loops into connected trees and group them according to their topological properties. Then, we identify a kernel generator, the so-called N7MLT universal topology, that allows us to describe any scattering amplitude of up to five loops. Furthermore, we provide factorization and recursion relations that enable us to write these multiloop topologies in terms of simpler subtopologies, including several subsets of Feynman diagrams with an arbitrary number of loops. Our approach takes advantage of many symmetries present in the graphical description of the original fundamental five-loop topologies. The results obtained in this article might shed light into a more efficient determination of higher-order corrections to the running couplings, which are crucial in the current and future precision physics program. |
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Address |
[Ramirez-Uribe, Selomit; Rodrigo, German] Univ Valencia, Inst Fis Corpuscular, Consejo Super Invest Cient, Parc Cient, E-46980 Paterna, Spain, Email: roger@uas.edu.mx |
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Mdpi |
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English |
Summary Language |
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Notes |
WOS:000904374000001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5450 |
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