| |
Records |
Links |
|
Author |
Mavromatos, N.E.; Mitsou, V.A. |
|
| |
Title |
Magnetic monopoles revisited: Models and searches at colliders and in the Cosmos |
Type |
Journal Article |
| |
Year |
2020 |
Publication |
International Journal of Modern Physics A |
Abbreviated Journal |
Int. J. Mod. Phys. A |
|
| |
Volume |
35 |
Issue |
23 |
Pages |
2030012 - 81pp |
|
| |
Keywords |
Magnetic monopoles; electromagnetism; theory; experimental techniques; searches; LHC; ATLAS; MoEDAL; IceCube; ANTARES |
|
| |
Abstract |
In this review, we discuss recent developments in both the theory and the experimental searches of magnetic monopoles in past, current and future colliders and in the Cosmos. The theoretical models include, apart from the standard Grand Unified Theories, extensions of the Standard Model that admit magnetic monopole solutions with finite energy and masses that can be as light as a few TeV. Specifically, we discuss, among other scenarios, modified Cho-Maison monopoles and magnetic monopoles in (string-inspired, higher derivative) Born-Infeld extensions of the hypercharge sector of the Standard Model. We also outline the conditions for which effective field theories describing the interaction of monopoles with photons are valid and can be used for result interpretation in monopole production at colliders. The experimental part of the review focuses on, past and present, cosmic and collider searches, including the latest bounds on monopole masses and magnetic charges by the ATLAS and MoEDAL experiments at the LHC, as well as prospects for future searches. |
|
| |
Address |
[Mavromatos, Nick E.] Kings Coll London, Dept Phys, Theoret Particle Phys & Cosmol Grp, London WC2R 2LS, England, Email: nikolaos.mavromatos@kcl.ac.uk; |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher  |
World Scientific Publ Co Pte Ltd |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0217-751x |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000563095400001 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
4516 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Bordes, J.; Chan, H.M.; Tsou, S.T. |
|
| |
Title |
delta(CP) for leptons and a new take on CP physics with the FSM |
Type |
Journal Article |
| |
Year |
2021 |
Publication |
International Journal of Modern Physics A |
Abbreviated Journal |
Int. J. Mod. Phys. A |
|
| |
Volume |
36 |
Issue |
|
Pages |
2150236 - 22pp |
|
| |
Keywords |
Phenomenology beyond the Standard Model; framed Standard Model; leptonic CP violation; CP physics |
|
| |
Abstract |
A bonus of the framed Standard Model (FSM), constructed initially to explain the mass and mixing patterns of quarks and leptons, is a solution (without axions) of the strong CP problem by cancelling the theta-angle term theta(I) Tr(H-mu v H-mu v*) in coloura by a chiral transformation on a quark zero mode which is inherent in FSM, and produces thereby a CP-violating phase in the CKM matrix similar in size to what is observed.' Extending here to flavour, one finds that there are two terms proportional to Tr(G(mu v) G(mu v)*): (a) in the action from flavour instantons with unknown coefficient, say theta(I)', (b) induced by the above FSM solution to the strong CP-problem with therefore known coefficient theta(C)'. Both terms can be cancelled in the FSM by a chiral transformation on the lepton zero mode to give a Jarlskog invariant J' in the PMNS matrix for leptons of order 10(-2), as is hinted by the experiment. But if, as suggested in Ref. 2, the term theta(I)' is to be cancelled by a chiral transformation in the predicted hidden sector to solve the strong CP problem therein, leaving only the term theta(C)' to be cancelled by the chiral transformation on leptons, then the following prediction results: J' similar to -0.012 (delta(CP)'similar to (1.11)pi) which is (i) of the right order, (ii) of the right sign and (iii) in the range favoured by the present experiment. Together with the earlier result for quarks, this offers an attractive unified treatment of all known CP physics. |
|
| |
Address |
[Bordes, Jose] Univ Valencia, Ctr Mixto CSIC, Dept Fis Teor, Calle Dr Moliner 50, E-46100 Burjassot, Valencia, Spain, Email: jose.m.bordes@uv.es; |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
World Scientific Publ Co Pte Ltd |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0217-751x |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000732963000007 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
5058 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Bordes, J.; Chan, H.M.; Tsou, S.T. |
|
| |
Title |
Unified FSM treatment of CP physics extended to hidden sector giving (i) delta(CP) for leptons as prediction, (ii) new hints on the material content of the universe |
Type |
Journal Article |
| |
Year |
2021 |
Publication |
International Journal of Modern Physics A |
Abbreviated Journal |
Int. J. Mod. Phys. A |
|
| |
Volume |
36 |
Issue |
|
Pages |
2150238 - 19pp |
|
| |
Keywords |
Phenomenology beyond the Standard Model; framed Standard Model; CP physics; dark matter |
|
| |
Abstract |
A unified treatment of CP physics for quarks and leptons in the framed Standard Model (FSM) is extended to include the predicted hidden sector giving as consequences: (i) that an earlier part estimate of the Jarlskog invariant J' for leptons is turned into a prediction for its actual value, i.e. J' similar to -0.012 (delta(CP)' similar to 1.11 pi), which is of the right order of magnitude, of the right sign, and in the range of values favoured by the present experiment, (ii) some novel twists to the effects of CP-violation on the material content of the universe. |
|
| |
Address |
[Bordes, Jose] Univ Valencia, Ctr Mixto CSIC, Dept Fis Teor, Calle Dr Moliner 50, E-46100 Burjassot, Valencia, Spain, Email: jose.m.bordes@uv.es; |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
World Scientific Publ Co Pte Ltd |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0217-751x |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000732963000005 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
5059 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Araujo Filho, A.A.; Reis, J.A.A.S.; Ghosh, S. |
|
| |
Title |
Quantum gases on a torus |
Type |
Journal Article |
| |
Year |
2023 |
Publication |
International Journal of Geometric Methods in Modern Physics |
Abbreviated Journal |
Int. J. Geom. Methods Mod. Phys. |
|
| |
Volume |
20 |
Issue |
10 |
Pages |
2350178 - 19pp |
|
| |
Keywords |
Thermodynamic properties; non-Cartesian geometries; grand canonical ensemble; noninteracting and interacting quantum gases; spinless; bosons and fermion particles |
|
| |
Abstract |
This paper is aimed at studying the thermodynamic properties of quantum gases confined to a torus. To do that, we consider noninteracting gases within the grand canonical ensemble formalism. In this context, fermions and bosons are taken into account and the calculations are properly provided in both analytical and numerical manners. In particular, the system turns out to be sensitive to the topological parameter under consideration: the winding number. Furthermore, we also derive a model in order to take into account interacting quantum gases. To corroborate our results, we implement such a method for two different scenarios: a ring and a torus. |
|
| |
Address |
[Araujo Filho, A. A.] Univ Fed Ceara UFC, Dept Fis, Campus Pici,CP 6030, BR-60455760 Fortaleza, CE, Brazil, Email: dilto@fisica.ufc.br; |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
World Scientific Publ Co Pte Ltd |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0219-8878 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000988814200003 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
5553 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Araujo Filho, A.A. |
|
| |
Title |
Thermodynamics of massless particles in curved spacetime |
Type |
Journal Article |
| |
Year |
2023 |
Publication |
International Journal of Geometric Methods in Modern Physics |
Abbreviated Journal |
Int. J. Geom. Methods Mod. Phys. |
|
| |
Volume |
12 |
Issue |
13 |
Pages |
2350226 - 40pp |
|
| |
Keywords |
Einstein-aether; thermodynamic properties; curved spacetime |
|
| |
Abstract |
This work is devoted to study the behavior of massless particles within the context of curved spacetime. In essence, we investigate the consequences of the scale factor C(?) of the Friedmann-Robertson-Walker metric in the Einstein-aether formalism to study photon-like particles. To do so, we consider the system within the canonical ensemble formalism in order to derive the following thermodynamic state quantities: spectral radiance, Helmholtz free energy, pressure, entropy, mean energy and the heat capacity. Moreover, the correction to the Stefan-Boltzmann law and the equation of states are also provided. Particularly, we separate our study within three distinct cases, i.e. s = 0, p = 0; s = 1, p = 1; s = 2, p = 1. In the first one, the results are derived numerically. Nevertheless, for the rest of the cases, all the calculations are accomplished analytically showing explicitly the dependence of the scale factor C(?) and the Riemann zeta function ?(s). Furthermore, our analyses are accomplished in general taking into account three different regimes of temperature of the universe, i.e. the inflationary era (T = 10(13)GeV), the electroweak epoch (T = 10(3)GeV) and the cosmic microwave background (T = 10(-13)GeV). |
|
| |
Address |
[Araujo Filho, A. A.] Univ Fed Cearra UFC, Dept Fis, Campus Pici,CP 6030, BR-60455760 Fortaleza, CE, Brazil, Email: dilto@fisica.ufc.br |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
World Scientific Publ Co Pte Ltd |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0219-8878 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:001048378900001 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
5613 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Bandos, I.A.; de Azcarraga, J.A.; Meliveo, C. |
|
| |
Title |
Conformal higher spin theory in extended tensorial superspace |
Type |
Journal Article |
| |
Year |
2012 |
Publication |
Fortschritte der Physik-Progress of Physics |
Abbreviated Journal |
Fortschritte Phys.-Prog. Phys. |
|
| |
Volume |
60 |
Issue |
7-8 |
Pages |
861-867 |
|
| |
Keywords |
Higher spin theory; conformal symmetry; superfields; tensorial superspaces |
|
| |
Abstract |
We discuss the formulation of free conformal higher spin theories with extended N = 2, 4, 8 supersymmetry in N-extended tensorial superspaces. The superfield higher spin equations can be obtained by quantizing a superparticle model in N-extended tensorial superspace. The N-extended higher spin supermultiplets just contain scalar and spinor fields in tensorial space so that, in contrast with the standard (super)space approach, no nontrivial generalizations of the Maxwell or Einstein equations to tensorial space appear when N > 2. For N = 4, 8, the higher spin-tensorial components of the extended tensorial superfields are expressed through additional scalar and spinor fields in tensorial space which obey the same free higher spin equations, but that are axion-like in the sense that they possess Peccei-Quinn-like symmetries. |
|
| |
Address |
[Bandos, Igor A.; Meliveo, Carlos] Univ Basque Country UPV EHU, Dept Theoret Phys, Bilbao 48080, Spain, Email: carlos_meliveo@ehu.es |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Wiley-V C H Verlag Gmbh |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0015-8208 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000306357900010 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
no |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
1095 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Norena, J.; Verde, L.; Jimenez, R.; Pena-Garay, C.; Gomez, C. |
|
| |
Title |
Cancelling out systematic uncertainties |
Type |
Journal Article |
| |
Year |
2012 |
Publication |
Monthly Notices of the Royal Astronomical Society |
Abbreviated Journal |
Mon. Not. Roy. Astron. Soc. |
|
| |
Volume |
419 |
Issue |
2 |
Pages |
1040-1050 |
|
| |
Keywords |
methods: statistical; cosmology: theory |
|
| |
Abstract |
We present a method to minimize, or even cancel out, the nuisance parameters affecting a measurement. Our approach is general and can be applied to any experiment or observation where systematic errors are a concern e.g. are larger than statistical errors. We compare it with the Bayesian technique used to deal with nuisance parameters: marginalization, and show how the method compares and improves by avoiding biases. We illustrate the method with several examples taken from the astrophysics and cosmology world: baryonic acoustic oscillations (BAOs), cosmic clocks, Type Ia supernova (SNIa) luminosity distance, neutrino oscillations and dark matter detection. By applying the method we not only recover some known results but also find some interesting new ones. For BAO experiments we show how to combine radial and angular BAO measurements in order to completely eliminate the dependence on the sound horizon at radiation drag. In the case of exploiting SNIa as standard candles we show how the uncertainty in the luminosity distance by a second parameter modelled as a metallicity dependence can be eliminated or greatly reduced. When using cosmic clocks to measure the expansion rate of the universe, we demonstrate how a particular combination of observables nearly removes the metallicity dependence of the galaxy on determining differential ages, thus removing the agemetallicity degeneracy in stellar populations. We hope that these findings will be useful in future surveys to obtain robust constraints on the dark energy equation of state. |
|
| |
Address |
[Norena, Jorge; Verde, Licia; Jimenez, Raul] Univ Barcelona IEEC UB, ICREA, Barcelona 08028, Spain, Email: jorge.norena@icc.ub.edu |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Wiley-Blackwell |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0035-8711 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000298482300011 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
no |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
890 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Albiol, A.; Corbi, A.; Albiol, F. |
|
| |
Title |
Automatic intensity windowing of mammographic images based on a perceptual metric |
Type |
Journal Article |
| |
Year |
2017 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
|
| |
Volume |
44 |
Issue |
4 |
Pages |
1369-1378 |
|
| |
Keywords |
contrast stretching; Gabor filtering; human visual system; mammogram; mutual information; window level/width |
|
| |
Abstract |
Purpose: Initial auto-adjustment of the window level WL and width WW applied to mammographic images. The proposed intensity windowing (IW) method is based on the maximization of the mutual information (MI) between a perceptual decomposition of the original 12-bit sources and their screen displayed 8-bit version. Besides zoom, color inversion and panning operations, IW is the most commonly performed task in daily screening and has a direct impact on diagnosis and the time involved in the process. Methods: The authors present a human visual system and perception-based algorithm named GRAIL (Gabor-relying adjustment of image levels). GRAIL initially measures a mammogram's quality based on the MI between the original instance and its Gabor-filtered derivations. From this point on, the algorithm performs an automatic intensity windowing process that outputs the WL/WW that best displays each mammogram for screening. GRAIL starts with the default, high contrast, wide dynamic range 12-bit data, and then maximizes the graphical information presented in ordinary 8-bit displays. Tests have been carried out with several mammogram databases. They comprise correlations and an ANOVA analysis with the manual IW levels established by a group of radiologists. A complete MATLAB implementation of GRAIL is available at . Results: Auto-leveled images show superior quality both perceptually and objectively compared to their full intensity range and compared to the application of other common methods like global contrast stretching (GCS). The correlations between the human determined intensity values and the ones estimated by our method surpass that of GCS. The ANOVA analysis with the upper intensity thresholds also reveals a similar outcome. GRAIL has also proven to specially perform better with images that contain micro-calcifications and/or foreign X-ray-opaque elements and with healthy BI-RADS A-type mammograms. It can also speed up the initial screening time by a mean of 4.5 s per image. Conclusions: A novel methodology is introduced that enables a quality-driven balancing of the WL/WW of mammographic images. This correction seeks the representation that maximizes the amount of graphical information contained in each image. The presented technique can contribute to the diagnosis and the overall efficiency of the breast screening session by suggesting, at the beginning, an optimal and customized windowing setting for each mammogram. |
|
| |
Address |
[Albiol, Alberto] Univ Politecn Valencia, iTeam Res Inst, Valencia, Spain, Email: alberto.corbi@ific.uv.es |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Wiley |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0094-2405 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000400572700016 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
no |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
3122 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Ma, Y.Z.; Vijande, J.; Ballester, F.; Tedgren, A.C.; Granero, D.; Haworth, A.; Mourtada, F.; Fonseca, G.P.; Zourari, K.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.; Chamberland, M.J.P.; Thomson, R.M.; Verhaegen, F.; Beaulieu, L. |
|
| |
Title |
A generic TG-186 shielded applicator for commissioning model-based dose calculation algorithms for high-dose-rate Ir-192 brachytherapy |
Type |
Journal Article |
| |
Year |
2017 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
|
| |
Volume |
44 |
Issue |
11 |
Pages |
5961-5976 |
|
| |
Keywords |
Ir-192; HDR brachytherapy; model based dose calculation; Monte Carlo methods; shielded applicator; TG-186 |
|
| |
Abstract |
PurposeA joint working group was created by the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) with the charge, among others, to develop a set of well-defined test case plans and perform calculations and comparisons with model-based dose calculation algorithms (MBDCAs). Its main goal is to facilitate a smooth transition from the AAPM Task Group No. 43 (TG-43) dose calculation formalism, widely being used in clinical practice for brachytherapy, to the one proposed by Task Group No. 186 (TG-186) for MBDCAs. To do so, in this work a hypothetical, generic high-dose rate (HDR) Ir-192 shielded applicator has been designed and benchmarked. MethodsA generic HDR Ir-192 shielded applicator was designed based on three commercially available gynecological applicators as well as a virtual cubic water phantom that can be imported into any DICOM-RT compatible treatment planning system (TPS). The absorbed dose distribution around the applicator with the TG-186 Ir-192 source located at one dwell position at its center was computed using two commercial TPSs incorporating MBDCAs (Oncentra((R)) Brachy with Advanced Collapsed-cone Engine, ACE, and BrachyVision ACUROS) and state-of-the-art Monte Carlo (MC) codes, including ALGEBRA, BrachyDose, egs_brachy, Geant4, MCNP6, and Penelope2008. TPS-based volumetric dose distributions for the previously reported source centered in water and source displaced test cases, and the new source centered in applicator test case, were analyzed here using the MCNP6 dose distribution as a reference. Volumetric dose comparisons of TPS results against results for the other MC codes were also performed. Distributions of local and global dose difference ratios are reported. ResultsThe local dose differences among MC codes are comparable to the statistical uncertainties of the reference datasets for the source centered in water and source displaced test cases and for the clinically relevant part of the unshielded volume in the source centered in applicator case. Larger local differences appear in the shielded volume or at large distances. Considering clinically relevant regions, global dose differences are smaller than the local ones. The most disadvantageous case for the MBDCAs is the one including the shielded applicator. In this case, ACUROS agrees with MC within [-4.2%, +4.2%] for the majority of voxels (95%) while presenting dose differences within [-0.12%, +0.12%] of the dose at a clinically relevant reference point. For ACE, 95% of the total volume presents differences with respect to MC in the range [-1.7%, +0.4%] of the dose at the reference point. ConclusionsThe combination of the generic source and generic shielded applicator, together with the previously developed test cases and reference datasets (available in the Brachytherapy Source Registry), lay a solid foundation in supporting uniform commissioning procedures and direct comparisons among treatment planning systems for HDR Ir-192 brachytherapy. |
|
| |
Address |
[Ma, Yunzhi; Beaulieu, Luc] CHU Quebec, Dept Radio Oncol & Axe Oncol, Ctr Rech, Quebec City, PQ G1R 2J6, Canada, Email: yunzhi.Ma@crchuq.ulaval.ca |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Wiley |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0094-2405 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000414970800039 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
3370 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Valdes-Cortez, C.; Niatsetski, Y.; Perez-Calatayud, J.; Ballester, F.; Vijande, J. |
|
| |
Title |
A Monte Carlo study of the relative biological effectiveness in surface brachytherapy |
Type |
Journal Article |
| |
Year |
2022 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
|
| |
Volume |
49 |
Issue |
|
Pages |
5576-5588 |
|
| |
Keywords |
Monte Carlo; relative biological effectiveness; surface HDR brachytherapy |
|
| |
Abstract |
Purpose This work aims to simulate clustered DNA damage from ionizing radiation and estimate the relative biological effectiveness (RBE) for radionuclide (rBT)- and electronic (eBT)-based surface brachytherapy through a hybrid Monte Carlo (MC) approach, using realistic models of the sources and applicators. Methods Damage from ionizing radiation has been studied using the Monte Carlo Damage Simulation algorithm using as input the primary electron fluence simulated using a state-of-the-art MC code, PENELOPE-2018. Two Ir-192 rBT applicators, Valencia and Leipzig, one Co-60 source with a Freiburg Flap applicator (reference source), and two eBT systems, Esteya and INTRABEAM, have been included in this study implementing full realizations of their geometries as disclosed by the manufacturer. The role played by filtration and tube kilovoltage has also been addressed. Results For rBT, an RBE value of about 1.01 has been found for the applicators and phantoms considered. In the case of eBT, RBE values for the Esteya system show an almost constant RBE value of about 1.06 for all depths and materials. For INTRABEAM, variations in the range of 1.12-1.06 are reported depending on phantom composition and depth. Modifications in the Esteya system, filtration, and tube kilovoltage give rise to variations in the same range. Conclusions Current clinical practice does not incorporate biological effects in surface brachytherapy. Therefore, the same absorbed dose is administered to the patients independently on the particularities of the rBT or eBT system considered. The almost constant RBE values reported for rBT support that assumption regardless of the details of the patient geometry, the presence of a flattening filter in the applicator design, or even significant modifications in the photon energy spectra above 300 keV. That is not the case for eBT, where a clear dependence on the eBT system and the characteristics of the patient geometry are reported. A complete study specific for each eBT system, including detailed applicator characteristics (size, shape, filtering, among others) and common anatomical locations, should be performed before adopting an existing RBE value. |
|
| |
Address |
[Valdes-Cortez, Christian] Hosp Reg Antofagasta, Nucl Med Dept, Antofagasta, Chile, Email: cvalcort@gmail.com |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Wiley |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0094-2405 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000811709400001 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
5262 |
|
| Permanent link to this record |
