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Aguiar, P., Rafecas, M., Ortuño, J. E., Kontaxakis, G., Santos, A., Pavia, J., et al. (2010). Geometrical and Monte Carlo projectors in 3D PET reconstruction. Med. Phys., 37(11), 5691–5702.
Abstract: Purpose: In the present work, the authors compare geometrical and Monte Carlo projectors in detail. The geometrical projectors considered were the conventional geometrical Siddon ray-tracer (S-RT) and the orthogonal distance-based ray-tracer (OD-RT), based on computing the orthogonal distance from the center of image voxel to the line-of-response. A comparison of these geometrical projectors was performed using different point spread function (PSF) models. The Monte Carlo-based method under consideration involves an extensive model of the system response matrix based on Monte Carlo simulations and is computed off-line and stored on disk. Methods: Comparisons were performed using simulated and experimental data of the commercial small animal PET scanner rPET. Results: The results demonstrate that the orthogonal distance-based ray-tracer and Siddon ray-tracer using PSF image-space convolutions yield better images in terms of contrast and spatial resolution than those obtained after using the conventional method and the multiray-based S-RT. Furthermore, the Monte Carlo-based method yields slight improvements in terms of contrast and spatial resolution with respect to these geometrical projectors. Conclusions: The orthogonal distance-based ray-tracer and Siddon ray-tracer using PSF image-space convolutions represent satisfactory alternatives to factorizing the system matrix or to the conventional on-the-fly ray-tracing methods for list-mode reconstruction, where an extensive modeling based on Monte Carlo simulations is unfeasible.
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Ballester, F., Granero, D., Perez-Calatayud, J., Venselaar, J. L. M., & Rivard, M. J. (2010). Study of encapsulated Tm-170 sources for their potential use in brachytherapy. Med. Phys., 37(4), 1629–1637.
Abstract: Methods: The authors have assumed a theoretical Tm-170 cylindrical source encapsulated with stainless steel and typical dimensions taken from the currently available HDR Ir-192 brachytherapy sources. The dose-rate distribution was calculated for this source using the GEANT4 Monte Carlo (MC) code considering both photon and electron Tm-170 spectra. The AAPM TG-43 U1 brachytherapy dosimetry parameters were derived. To study general properties of Tm-170 encapsulated sources, spherical sources encapsulated with stainless steel and platinum were also studied. Moreover, the influence of small variations in the active core and capsule dimensions on the dosimetric characteristics was assessed. Treatment times required for a Tm-170 source were compared to those for Ir-192 and Yb-169 for the same contained activity. Results: Due to the energetic beta spectrum and the large electron yield, the bremsstrahlung contribution to the dose was of the same order of magnitude as from the emitted gammas and characteristic x rays. Moreover, the electron spectrum contribution to the dose was significant up to 4 mm from the source center compared to the photon contribution. The dose-rate constant Lambda of the cylindrical source was 1.23 cGy h(-1) U-1. The behavior of the radial dose function showed promise for applications in brachytherapy. Due to the electron spectrum, the anisotropy was large for r < 6 mm. Variations in manufacturing tolerances did not significantly influence the final dosimetry data when expressed in cGy h(-1) U-1. For typical capsule dimensions, maximum reference dose rates of about 0.2, 10, and 2 Gy min(-1) would then be obtained for Tm-170, Ir-192, and Yb-169, respectively, resulting in treatment times greater than those for HDR Ir-192 brachytherapy. Conclusions: The dosimetric characteristics of source designs exploiting the low photon energy of Tm-170 were studied for potential application in HDR-brachytherapy. Dose-rate distributions were obtained for cylindrical and simplified spherical Tm-170 source designs (stainless steel and platinum capsule materials) using MC calculations. Despite the high activity of Tm-170, calculated treatment times were much longer than for Ir-192.
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Rivard, M. J., Granero, D., Perez-Calatayud, J., & Ballester, F. (2010). Influence of photon energy spectra from brachytherapy sources on Monte Carlo simulations of kerma and dose rates in water and air. Med. Phys., 37(2), 869–876.
Abstract: Methods: For Ir-192, I-125, and Pd-103, the authors considered from two to five published spectra. Spherical sources approximating common brachytherapy sources were assessed. Kerma and dose results from GEANT4, MCNP5, and PENELOPE-2008 were compared for water and air. The dosimetric influence of Ir-192, I-125, and Pd-103 spectral choice was determined. Results: For the spectra considered, there were no statistically significant differences between kerma or dose results based on Monte Carlo code choice when using the same spectrum. Water-kerma differences of about 2%, 2%, and 0.7% were observed due to spectrum choice for Ir-192, I-125, and Pd-103, respectively (independent of radial distance), when accounting for photon yield per Bq. Similar differences were observed for air-kerma rate. However, their ratio (as used in the dose-rate constant) did not significantly change when the various photon spectra were selected because the differences compensated each other when dividing dose rate by air-kerma strength. Conclusions: Given the standardization of radionuclide data available from the National Nuclear Data Center (NNDC) and the rigorous infrastructure for performing and maintaining the data set evaluations, NNDC spectra are suggested for brachytherapy simulations in medical physics applications.
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Decoster, S., Cottenier, S., Wahl, U., Correia, J. G., Pereira, L. M. C., Lacasta, C., et al. (2010). Diluted manganese on the bond-centered site in germanium. Appl. Phys. Lett., 97(15), 151914–3pp.
Abstract: The functional properties of Mn-doped Ge depend to large extent on the lattice location of the Mn impurities. Here, we present a lattice location study of implanted diluted Mn by means of electron emission channeling. Surprisingly, in addition to the expected substitutional lattice position, a large fraction of the Mn impurities occupies the bond-centered site. Corroborated by ab initio calculations, the bond-centered Mn is related to Mn-vacancy complexes. These unexpected results call for a reassessment of the theoretical studies on the electrical and magnetic behavior of Mn-doped Ge, hereby including the possible role of Mn-vacancy complexes.
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Rafi Alam, M., Ruiz Simo, I., Sajjad Athar, M., & Vicente Vacas, M. J. (2010). Weak kaon production off the nucleon. Phys. Rev. D, 82(3), 033001–8pp.
Abstract: The weak kaon production off the nucleon induced by neutrinos is studied at the low and intermediate energies of interest for some ongoing and future neutrino oscillation experiments. This process is also potentially important for the analysis of proton decay experiments. We develop a microscopical model based on the SU(3) chiral Lagrangians. The basic parameters of the model are f pi, the pion decay constant, Cabibbo's angle, the proton and neutron magnetic moments, and the axial vector coupling constants for the baryons octet, D and F, that are obtained from the analysis of the semileptonic decays of neutron and hyperons. The studied mechanisms are the main source of kaon production for neutrino energies up to 1.2 to 1.5 GeV for the various channels and the cross sections are large enough to be amenable to be measured by experiments such as Minerva and T2K.
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BABAR Collaboration(del Amo Sanchez, P. et al), Azzolini, V., Lopez-March, N., Martinez-Vidal, F., Milanes, D. A., & Oyanguren, A. (2010). Observation of the rare decay B-0 -> K-S(0) K-+/-pi(-/+). Phys. Rev. D, 82(3), 031101–8pp.
Abstract: We report an analysis of charmless hadronic decays of neutral B mesons to the final state (KSK +/-)-K-0 pi(-/+) (sic), using a data sample of (465 +/- 5) x 10(6) B (B) over bar events collected with the BABAR detector at the Gamma(4S) resonance. We observe an excess of signal events with a significance of 5.2 standard deviations including systematic uncertainties and measure the branching fraction to be B(B-0 -> (KSK +/-)-K-0 pi(-/+) (sic) (3.2 +/- 0.5 +/- 0.3) x 10(-6), where the uncertainties are statistical and systematic, respectively.
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de Putter, R., & Takada, M. (2010). Halo-galaxy lensing: A full sky approach. Phys. Rev. D, 82(10), 103522–9pp.
Abstract: The halo-galaxy lensing correlation function or the average tangential shear profile over sampled halos is a very powerful means of measuring the halo masses, the mass profile, and the halo-mass correlation function of very large separations in the linear regime. We reformulate the halo-galaxy lensing correlation in harmonic space. We find that, counterintuitively, errors in the conventionally used flat-sky approximation remain at a percent level even at very small angles. The errors increase at larger angles and for lensing halos at lower redshifts: the effect is at a few percent level at the baryonic acoustic oscillation scales for lensing halos of z similar to 0.2, and comparable with the effect of primordial non-Gaussianity with f(NL) similar to 10 at large separations. Our results allow one to readily estimate/correct for the full-sky effect on a high-precision measurement of the average shear profile available from upcoming wide-area lensing surveys.
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KTeV Collaboration(Abouzaid, E. et al), & Passemar, E. (2010). Dispersive analysis of KLmu3 and KLe3 scalar and vector form factors using KTeV data. Phys. Rev. D, 81(5), 052001–9pp.
Abstract: Using the published KTeV samples of K-L -> pi(+/-)e(-/+)nu and K-L -> pi(+/-)mu(-/+)nu decays, we perform a reanalysis of the scalar and vector form factors based on the dispersive parametrization. We obtain phase-space integrals I-K(e) = 0.15446 +/- 0.00025 and I-K(mu) = 0.10219 +/- 0.00025. For the scalar form factor parametrization, the only free parameter is the normalized form factor value at the Callan-Treiman point (C); our best-fit results in InC = 0.1915 +/- 0.0122. We also study the sensitivity of C to different parametrizations of the vector form factor. The results for the phase-space integrals and C are then used to make tests of the standard model. Finally, we compare our results with lattice QCD calculations of F-K/F-pi and f(+)(0).
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MiniBooNE Collaboration(Aguilar-Arevalo, A. A. et al), & Sorel, M. (2010). Measurement of the neutrino neutral-current elastic differential cross section on mineral oil at E-nu similar to 1 GeV. Phys. Rev. D, 82(9), 092005–16pp.
Abstract: We report a measurement of the flux-averaged neutral-current elastic differential cross section for neutrinos scattering on mineral oil (CH2) as a function of four-momentum transferred squared, Q(2). It is obtained by measuring the kinematics of recoiling nucleons with kinetic energy greater than 50 MeV which are readily detected in MiniBooNE. This differential cross-section distribution is fit with fixed nucleon form factors apart from an axial mass M-A that provides a best fit for M-A = 1.39 +/- 0.11 GeV. Using the data from the charged-current neutrino interaction sample, a ratio of neutral-current to charged-current quasielastic cross sections as a function of Q(2) has been measured. Additionally, single protons with kinetic energies above 350 MeV can be distinguished from neutrons and multiple nucleon events. Using this marker, the strange quark contribution to the neutral-current axial vector form factor at Q(2) – 0, Delta s, is found to be Delta s = 0.08 +/- 0.26.
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MiniBooNE Collaboration(Aguilar-Arevalo, A. A. et al), & Sorel, M. (2010). Event Excess in the MiniBooNE Search for (nu)over-bar(mu) -> (nu)over-bar(e) Oscillations. Phys. Rev. Lett., 105(18), 181801–5pp.
Abstract: The MiniBooNE experiment at Fermilab reports results from a search for (nu) over bar (mu) -> (nu) over bar (e) oscillations, using a data sample corresponding to 5.66 x 10(20) protons on target. An excess of 20.9 +/- 14.0 events is observed in the energy range 475 < E-nu(QE) < 1250 MeV, which, when constrained by the observed <(nu)over bar>(mu) events, has a probability for consistency with the background-only hypothesis of 0.5%. On the other hand, fitting for (nu) over bar (mu) -> (nu) over bar (e) oscillations, the best-fit point has chi(2) probability of 8.7%. The data are consistent with (nu) over bar (mu) -> (nu) over bar (e) oscillations in the 0.1 to 1.0 eV(2) Delta m(2) range and with the evidence for antineutrino oscillations from the Liquid Scintillator Neutrino Detector at Los Alamos National Laboratory.
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