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Author |
Richard, J.M.; Valcarce, A.; Vijande, J. |
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Title |
Hall-Post inequalities: Review and application to molecules and tetraquarks |
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Journal Article |
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Year |
2020 |
Publication |
Annals of Physics |
Abbreviated Journal |
Ann. Phys. |
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Volume |
412 |
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Pages |
168009 - 32pp |
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Keywords |
Hall-Post inequality; Few Body; Molecule; Quark model; Baryons; Tetraquark |
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Abstract |
A review is presented of the Hall-Post inequalities that give lower-bounds to the ground-state energy of quantum systems in terms of energies of smaller systems. New applications are given for systems experiencing both a static source and inner interactions, as well as for hydrogen-like molecules and for tetraquarks in some quark models. In the latter case, the Hall-Post inequalities constrain the possibility of deeply-bound exotic mesons below the threshold for dissociation into two quark-antiquark mesons. We also emphasize the usefulness of the Hall-Post bounds in terms of 3-body energies when some 2-body subsystems are ill defined or do not support any bound state. |
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Address |
[Richard, Jean-Marc] Univ Lyon, Inst Phys Deux Infinis, IN2P3, CNRS,UCBL, 4 Rue Enrico Fermi, F-69622 Villeurbanne, France, Email: j-m.richard@ipnl.in2p3.fr; |
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Academic Press Inc Elsevier Science |
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0003-4916 |
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WOS:000509419600017 |
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no |
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yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4262 |
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Author |
Granero, D.; Vijande, J.; Ballester, F.; Rivard, M.J. |
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Title |
Dosimetry revisited for the HDR Ir-192 brachytherapy source model mHDR-v2 |
Type |
Journal Article |
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Year |
2011 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
38 |
Issue |
1 |
Pages |
487-494 |
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Keywords |
Ir-192; brachytherapy; dosimetry; TG-43; PSS model; MCNP5; PENELOPE2008; GEANT4 |
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Abstract |
Purpose: Recently, the manufacturer of the HDR Ir-192 mHDR-v2 brachytherapy source reported small design changes (referred to herein as mHDR-v2r) that are within the manufacturing tolerances but may alter the existing dosimetric data for this source. This study aimed to (1) check whether these changes affect the existing dosimetric data published for this source; (2) obtain new dosimetric data in close proximity to the source, including the contributions from 192Ir electrons and considering the absence of electronic equilibrium; and (3) obtain scatter dose components for collapsed cone treatment planning system implementation. Methods: Three different Monte Carlo (MC) radiation transport codes were used: MCNP5, PENELOPE2008, and GEANT4. The source was centrally positioned in a 40 cm radius water phantom. Absorbed dose and collision kerma were obtained using 0.1 mm (0.5 mm) thick voxels to provide high-resolution dosimetry near (far from) the source. Dose-rate distributions obtained with the three MC codes were compared. Results: Simulations of mHDR-v2 and mHDR-v2r designs performed with three radiation transport codes showed agreement typically within 0.2% for r >= 0.25 cm. Dosimetric contributions from source electrons were significant for r<0.25 cm. The dose-rate constant and radial dose function were similar to those from previous MC studies of the mHDR-v2 design. The 2D anisotropy function also coincided with that of the mHDR-v2 design for r >= 0.25 cm. Detailed results of dose distributions and scatter components are presented for the modified source design. Conclusions: Comparison of these results to prior MC studies showed agreement typically within 0.5% for r >= 0.25 cm. If dosimetric data for r<0.25 cm are not needed, dosimetric results from the prior MC studies will be adequate. c 2011 American Association of Physicists in Medicine. |
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Address |
[Granero, Domingo] Hosp Gen Univ, Dept Radiat Phys, ERESA, E-46014 Valencia, Spain, Email: dgranero@eresa.com |
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Amer Assoc Physicists Medicine Amer Inst Physics |
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English |
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0094-2405 |
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Notes |
ISI:000285769800050 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
557 |
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Author |
Granero, D.; Perez-Calatayud, J.; Vijande, J.; Ballester, F.; Rivard, M.J. |
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Title |
Limitations of the TG-43 formalism for skin high-dose-rate brachytherapy dose calculations |
Type |
Journal Article |
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Year |
2014 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
41 |
Issue |
2 |
Pages |
021703 - 8pp |
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Keywords |
HDR; brachytherapy; skin; Monte Carlo; Geant4; Co-60; Ir-192; Yb-169 |
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Abstract |
Purpose: In skin high-dose-rate (HDR) brachytherapy, sources are located outside, in contact with, or implanted at some depth below the skin surface. Most treatment planning systems use the TG-43 formalism, which is based on single-source dose superposition within an infinite water medium without accounting for the true geometry in which conditions for scattered radiation are altered by the presence of air. The purpose of this study is to evaluate the dosimetric limitations of the TG-43 formalism in HDR skin brachytherapy and the potential clinical impact. Methods: Dose rate distributions of typical configurations used in skin brachytherapy were obtained: a 5 cm x 5 cm superficial mould; a source inside a catheter located at the skin surface with and without backscatter bolus; and a typical interstitial implant consisting of an HDR source in a catheter located at a depth of 0.5 cm. Commercially available HDR Co-60 and Ir-192 sources and a hypothetical Yb-169 source were considered. The Geant4Monte Carlo radiation transport code was used to estimate dose rate distributions for the configurations considered. These results were then compared to those obtained with the TG-43 dose calculation formalism. In particular, the influence of adding bolus material over the implant was studied. Results: For a 5 cm x 5 cm Ir-192 superficial mould and 0.5 cm prescription depth, dose differences in comparison to the TG-43 method were about -3%. When the source was positioned at the skin surface, dose differences were smaller than -1% for Co-60 and Ir-192, yet -3% for Yb-169. For the interstitial implant, dose differences at the skin surface were -7% for Co-60, -0.6% for Ir-192, and -2.5% for Yb-169. Conclusions: This study indicates the following: (i) for the superficial mould, no bolus is needed; (ii) when the source is in contact with the skin surface, no bolus is needed for either Co-60 and Ir-192. For lower energy radionuclides like Yb-169, bolus may be needed; and (iii) for the interstitial case, at least a 0.1 cm bolus is advised for Co-60 to avoid underdosing superficial target layers. For Ir-192 and Yb-169, no bolus is needed. For those cases where no bolus is needed, its use might be detrimental as the lack of radiation scatter may be beneficial to the patient, although the 2% tolerance for dose calculation accuracy recommended in the AAPM TG-56 report is not fulfilled. |
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[Granero, Domingo] Hosp Gen Univ, ERESA, Dept Radiat Phys, Valencia 46014, Spain, Email: dgranero@eresa.com |
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Amer Assoc Physicists Medicine Amer Inst Physics |
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English |
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0094-2405 |
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Notes |
WOS:000331213300006 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1704 |
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Author |
Ballester, F.; Tedgren, A.C.; Granero, D.; Haworth, A.; Mourtada, F.; Fonseca, G.P.; Zourari, K.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.L.; Thomson, R.M.; Verhaegen, F.; Vijande, J.; Ma, Y.Z.; Beaulieu, L. |
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Title |
A generic high-dose rate Ir-192 brachytherapy source for evaluation of model-based dose calculations beyond the TG-43 formalism |
Type |
Journal Article |
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Year |
2015 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
42 |
Issue |
6 |
Pages |
3048-3062 |
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Keywords |
Ir-192; HDR brachytherapy; Monte Carlo methods; model-based dose calculation; TG-186 |
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Abstract |
Purpose: In order to facilitate a smooth transition for brachytherapy dose calculations from the American Association of Physicists in Medicine (AAPM) Task Group No. 43 (TG-43) formalism to model-based dose calculation algorithms (MBDCAs), treatment planning systems (TPSs) using a MBDCA require a set of well-defined test case plans characterized by Monte Carlo (MC) methods. This also permits direct dose comparison to TG-43 reference data. Such test case plans should be made available for use in the software commissioning process performed by clinical end users. To this end, a hypothetical, generic high-dose rate (HDR) Ir-192 source and a virtual water phantom were designed, which can be imported into a TPS. Methods: A hypothetical, generic HDR Ir-192 source was designed based on commercially available sources as well as a virtual, cubic water phantom that can be imported into any TPS in DICOM format. The dose distribution of the generic Ir-192 source when placed at the center of the cubic phantom, and away from the center under altered scatter conditions, was evaluated using two commercial MBDCAs [Oncentra (R) Brachy with advanced collapsed-cone engine (ACE) and BrachyVision AcuRos (TM)]. Dose comparisons were performed using state-of-the-art MC codes for radiation transport, including ALGEBRA, BrachyDose, GEANT4, MCNP5, MCNP6, and pENELopE2008. The methodologies adhered to recommendations in the AAPM TG-229 report on high-energy brachytherapy source dosimetry. TG-43 dosimetry parameters, an along-away dose-rate table, and primary and scatter separated (PSS) data were obtained. The virtual water phantom of (201)(3) voxels (1 mm sides) was used to evaluate the calculated dose distributions. Two test case plans involving a single position of the generic HDR Ir-192 source in this phantom were prepared: (i) source centered in the phantom and (ii) source displaced 7 cm laterally from the center. Datasets were independently produced by different investigators. MC results were then compared against dose calculated using TG-43 and MBDCA methods. Results: TG-43 and PSS datasets were generated for the generic source, the PSS data for use with the ACE algorithm. The dose-rate constant values obtained from seven MC simulations, performed independently using different codes, were in excellent agreement, yielding an average of 1.1109 +/- 0.0004 cGy/(h U) (k = 1, Type A uncertainty). MC calculated dose-rate distributions for the two plans were also found to be in excellent agreement, with differences within type A uncertainties. Differences between commercial MBDCA and MC results were test, position, and calculation parameter dependent. On average, however, these differences were within 1% for ACUROS and 2% for ACE at clinically relevant distances. Conclusions: A hypothetical, generic HDR Ir-192 source was designed and implemented in two commercially available TPSs employing different MBDCAs. Reference dose distributions for this source were benchmarked and used for the evaluation of MBDCA calculations employing a virtual, cubic water phantom in the form of a CT DICOM image series. The implementation of a generic source of identical design in all TPSs using MBDCAs is an important step toward supporting univocal commissioning procedures and direct comparisons between TPSs. |
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Address |
[Ballester, Facundo] Univ Valencia, Dept Atom Mol & Nucl Phys, E-46100 Burjassot, Spain, Email: Facundo.Ballester@uv.es |
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Amer Assoc Physicists Medicine Amer Inst Physics |
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English |
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0094-2405 |
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Notes |
WOS:000356998300031 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2315 |
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Author |
Candela-Juan, C.; Vijande, J.; Garcia-Martinez, T.; Niatsetski, Y.; Nauta, G.; Schuurman, J.; Ouhib, Z.; Ballester, F.; Perez-Calatayud, J. |
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Title |
Comparison and uncertainty evaluation of different calibration protocols and ionization chambers for low-energy surface brachytherapy dosimetry |
Type |
Journal Article |
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Year |
2015 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
42 |
Issue |
8 |
Pages |
4954-4964 |
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Keywords |
x-ray beams; electronic brachytherapy; surface applicators; dosimetry; uncertainty |
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Abstract |
Purpose: A surface electronic brachytherapy (EBT) device is in fact an x-ray source collimated with specific applicators. Low-energy (<100 kVp) x-ray beam dosimetry faces several challenges that need to be addressed. A number of calibration protocols have been published for x-ray beam dosimetry. The media in which measurements are performed are the fundamental difference between them. The aim of this study was to evaluate the surface dose rate of a low-energy x-ray source with small field applicators using different calibration standards and different small-volume ionization chambers, comparing the values and uncertainties of each methodology. Methods: The surface dose rate of the EBT unit Esteya (Elekta Brachytherapy, The Netherlands), a 69.5 kVp x-ray source with applicators of 10, 15, 20, 25, and 30 mm diameter, was evaluated using the AAPM TG-61 (based on air kerma) and International Atomic Energy Agency (IAEA) TRS-398 (based on absorbed dose to water) dosimetry protocols for low-energy photon beams. A plane parallel T34013 ionization chamber (PTW Freiburg, Germany) calibrated in terms of both absorbed dose to water and air kerma was used to compare the two dosimetry protocols. Another PTW chamber of the same model was used to evaluate the reproducibility between these chambers. Measurements were also performed with two different Exradin A20 (Standard Imaging, Inc., Middleton, WI) chambers calibrated in terms of air kerma. Results: Differences between surface dose rates measured in air and in water using the T34013 chamber range from 1.6% to 3.3%. No field size dependence has been observed. Differences are below 3.7% when measurements with the A20 and the T34013 chambers calibrated in air are compared. Estimated uncertainty (with coverage factor k = 1) for the T34013 chamber calibrated in water is 2.2%-2.4%, whereas it increases to 2.5% and 2.7% for the A20 and T34013 chambers calibrated in air, respectively. The output factors, measured with the PTW chambers, differ by less than 1.1% for any applicator size when compared to the output factors that were measured with the A20 chamber. Conclusions: Measurements using both dosimetric protocols are consistent, once the overall uncertainties are considered. There is also consistency between measurements performed with both chambers calibrated in air. Both the T34013 and A20 chambers have negligible stem effect. Any x-ray surface brachytherapy system, including Esteya, can be characterized using either one of these calibration protocols and ionization chambers. Having less correction factors, lower uncertainty, and based on measurements, performed in closer to clinical conditions, the TRS-398 protocol seems to be the preferred option. |
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Address |
[Candela-Juan, C.; Perez-Calatayud, J.] La Fe Univ, Dept Radiat Oncol, Valencia 46026, Spain, Email: ccanjuan@gmail.com |
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Amer Assoc Physicists Medicine Amer Inst Physics |
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English |
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0094-2405 |
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Notes |
WOS:000358933000051 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2323 |
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Author |
Candela-Juan, C.; Niatsetski, Y.; van der Laarse, R.; Granero, D.; Ballester, F.; Perez-Calatayud, J.; Vijande, J. |
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Title |
Design and characterization of a new high-dose-rate brachytherapy Valencia applicator for larger skin lesions |
Type |
Journal Article |
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Year |
2016 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
43 |
Issue |
4 |
Pages |
1639-1648 |
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Keywords |
skin applicator; Valencia applicator; HDR brachytherapy; dosimetry; Monte Carlo |
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Abstract |
Purpose: The aims of this study were (i) to design a new high-dose-rate (HDR) brachytherapy applicator for treating surface lesions with planning target volumes larger than 3 cm in diameter and up to 5 cm in size, using the microSelectron-HDR or Flexitron afterloader (Elekta Brachytherapy) with a Ir-192 source; (ii) to calculate by means of the Monte Carlo (MC) method the dose distribution for the new applicator when it is placed against a water phantom; and (iii) to validate experimentally the dose distributions in water. Methods: The PENELOPE2008 MC code was used to optimize dwell positions and dwell times. Next, the dose distribution in a water phantom and the leakage dose distribution around the applicator were calculated. Finally, MC data were validated experimentally for a 192Ir mHDR-v2 source by measuring (i) dose distributions with radiochromic EBT3 films (ISP); (ii) percentage depth-dose (PDD) curve with the parallel-plate ionization chamber Advanced Markus (PTW); and (iii) absolute dose rate with EBT3 films and the PinPoint T31016 (PTW) ionization chamber. Results: The new applicator is made of tungsten alloy (Densimet) and consists of a set of interchangeable collimators. Three catheters are used to allocate the source at prefixed dwell positions with preset weights to produce a homogenous dose distribution at the typical prescription depth of 3 mm in water. The same plan is used for all available collimators. PDD, absolute dose rate per unit of air kerma strength, and off-axis profiles in a cylindrical water phantom are reported. These data can be used for treatment planning. Leakage around the applicator was also scored. The dose distributions, PDD, and absolute dose rate calculated agree within experimental uncertainties with the doses measured: differences of MC data with chamber measurements are up to 0.8% and with radiochromic films are up to 3.5%. Conclusions: The new applicator and the dosimetric data provided here will be a valuable tool in clinical practice, making treatment of large skin lesions simpler, faster, and safer. Also the dose to surrounding healthy tissues is minimal. |
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Address |
[Candela-Juan, C.; Perez-Calatayud, J.] La Fe Univ & Polytech Hosp, Dept Radiat Oncol, Valencia 46026, Spain, Email: ccanjuan@gmail.com |
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Amer Assoc Physicists Medicine Amer Inst Physics |
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English |
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0094-2405 |
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Conference |
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Notes |
WOS:000373711000007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2620 |
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Author |
Granero, D.; Candela-Juan, C.; Vijande, J.; Ballester, F.; Perez-Calatayud, J.; Jacob, D.; Mourtada, F. |
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Title |
Technical Note: Dosimetry of Leipzig and Valencia applicators without the plastic cap |
Type |
Journal Article |
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Year |
2016 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
43 |
Issue |
5 |
Pages |
2087 - 4pp |
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Keywords |
Leipzig applicators; Valencia applicators; skin brachytherapy; Monte Carlo; dosimetry |
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Abstract |
Purpose: High dose rate (HDR) brachytherapy for treatment of small skin lesions using the Leipzig and Valencia applicators is a widely used technique. These applicators are equipped with an attachable plastic cap to be placed during fraction delivery to ensure electronic equilibrium and to prevent secondary electrons from reaching the skin surface. The purpose of this study is to report on the dosimetric impact of the cap being absent during HDR fraction delivery, which has not been explored previously in the literature. Methods: GEANT4 Monte Carlo simulations (version 10.0) have been performed for the Leipzig and Valencia applicators with and without the plastic cap. In order to validate the Monte Carlo simulations, experimental measurements using radiochromic films have been done. Results: Dose absorbed within 1 mm of the skin surface increases by a factor of 1500% for the Leipzig applicators and of 180% for the Valencia applicators. Deeper than 1 mm, the overdosage flattens up to a 10% increase. Conclusions: Differences of treating with or without the plastic cap are significant. Users must check always that the plastic cap is in place before any treatment in order to avoid overdosage of the skin. Prior to skin HDR fraction delivery, the timeout checklist should include verification of the cap placement. (C) 2016 American Association of Physicists in Medicine. |
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Address |
[Granero, D.] Hosp Gen Univ, Dept Radiat Phys, ERESA, Valencia 46014, Spain, Email: dgranero@eresa.com |
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Amer Assoc Physicists Medicine Amer Inst Physics |
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English |
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0094-2405 |
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Notes |
WOS:000378924200010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2753 |
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Author |
Fernandez-Carames, T.; Valcarce, A.; Vijande, J. |
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Title |
Charged charmonium molecules |
Type |
Journal Article |
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Year |
2010 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
82 |
Issue |
5 |
Pages |
054032 - 5pp |
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Abstract |
We make use of a self-consistent quark-model based study of four-quark charmonium-like states to interpret recent charmonium experimental data. We conclude that there exists a D*(D) over bar* meson-meson molecule with quantum numbers (I-G) J(PC) = (1(-))2(++). Our study confirms the presence of charged charmonium-like resonances on the excited charmonium spectrum. We find support from recent experimental data by the Belle Collaboration [R. Mizuk et al. (Belle Collaboration), Phys. Rev. D 78, 072004 (2008)]. Confirmation of the experimental data by the Belle Collaboration and the determination of the quantum numbers of the new structures would help in discriminating among different theoretical models and would give further support to the theoretical analysis of T. Fernandez-Carames, A. Valcarce, and J. Vijande [Phys. Rev. Lett. 103, 222001 (2009)]. |
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Address |
[Carames, T. F.; Valcarce, A.] Univ Salamanca, Dept Fis Fundamental, E-37008 Salamanca, Spain |
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Publisher |
Amer Physical Soc |
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English |
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1550-7998 |
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Notes |
ISI:000282271100006 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ elepoucu @ |
Serial |
366 |
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| Permanent link to this record |
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Author |
Vijande, J.; Valcarce, A.; Richard, J.M. |
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Title |
Stability of hexaquarks in the string limit of confinement |
Type |
Journal Article |
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Year |
2012 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
85 |
Issue |
1 |
Pages |
014019 - 6pp |
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Keywords |
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Abstract |
The stability of systems containing six quarks or antiquarks is studied within a simple string model inspired by the strong-coupling regime of quantum chromodynamics and used previously for tetraquarks and pentaquarks. We discuss both six-quark (q(6)) and three-quark-three-antiquark (q(3)($) over bar (3)) states. The quarks are assumed to be distinguishable and thus not submitted to antisymmetrization. It is found that the ground state of (q(6)) is stable against dissociation into two isolated baryons. For the case of (q(3)($) over bar (3)), our results indicate the existence of a bound state very close to the threshold. The investigations are extended to (q(3)Q(3)) and (Q(3) ($) over bar (3)) systems with two different constituent masses, and their stability is discussed as a function of the mass ratio. |
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Address |
[Vijande, J.] Univ Valencia, Dept Fis Atom Mol & Nucl, Valencia, Spain, Email: javier.vijande@uv.es |
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Corporate Author |
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Thesis |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1550-7998 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000299293600006 |
Approved |
no |
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| |
Is ISI |
yes |
International Collaboration |
yes |
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| |
Call Number |
IFIC @ pastor @ |
Serial |
883 |
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| Permanent link to this record |
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Author |
Vijande, J.; Valcarce, A.; Richard, J.M. |
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Title |
Adiabaticity and color mixing in tetraquark spectroscopy |
Type |
Journal Article |
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Year |
2013 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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| |
Volume |
87 |
Issue |
3 |
Pages |
034040 - 5pp |
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Keywords |
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Abstract |
We revisit the role of color mixing in the quark model calculation of tetraquark states, and compare simple pairwise potentials to more elaborate string models with three-and four-body forces. We attempt to disentangle the improved dynamics of confinement from the approximations made in the treatment of the internal color degrees of freedom. |
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Address |
[Vijande, J.] Univ Valencia, Dept Fis Atom Mol & Nucl, E-46100 Valencia, Spain, Email: javier.vijande@uv.es; |
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Corporate Author |
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Thesis |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1550-7998 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000315484000002 |
Approved |
no |
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| |
Is ISI |
yes |
International Collaboration |
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Call Number |
IFIC @ pastor @ |
Serial |
1350 |
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| Permanent link to this record |
