Abstract: Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range.

Abstract: In modular invariant models of flavor, observables must be modular invariant. The observables discussed so far in the literature are functions of the modulus tau and its conjugate, (tau) over bar. We point out that certain combinations of observables depend only on tau , i.e. are meromorphic, and in some cases even holomorphic functions of tau. These functions, which we dub “invariants” in this Letter, are highly constrained, renormalization group invariant, and allow us to derive many of the models' features without the need for extensive parameter scans. We illustrate the robustness of these invariants in two existing models in the literature based on modular symmetries, Gamma(3) and Gamma(5). We find that, in some cases, the invariants give rise to robust relations among physical observables that are independent of tau. Furthermore, there are instances where additional symmetries exist among the invariants. These symmetries are relevant phenomenologically and may provide a dynamical way to realize symmetries of mass matrices.

Abstract: We analyze the modifications that a dense nuclear medium induces in the D-s0*(2317)(+/-) and D-s1(2460)(+/-). In the vacuum, we consider them as isoscalar D-(*K-) and (D) over bar (()*())(K) over bar S-wave bound states, which are dynamically generated from effective interactions that lead to different Weinberg compositeness scenarios. Matter effects are incorporated through the two-meson loop functions, taking into account the self energies that the D-(*()), (D) over bar (()*()), K, and (K) over bar develop when embedded in a nuclear medium. Although particle-antiparticle [D-s0,s1(()*())(2317,2460)(+) versus D-s0,s1(()*())(2317,2460)(-)] lineshapes are the same in vacuum, we find extremely different density patterns in matter. This charge-conjugation asymmetry mainly stems from the very different kaon and antikaon interaction with the nucleons of the dense medium. We show that the in-medium lineshapes found for these resonances strongly depend on their D-(*()), K/(D) over bar (()*()), K molecular content, and discuss how this novel feature can be used to better determine/constrain the inner structure of these exotic states.

Abstract: Lifetime measurements of low-lying excited states in the semimagic ( N = 50) nucleus 95 Rh have been performed by means of the fast -timing technique. The experiment was carried out using gamma -ray detector arrays consisting of LaBr 3 (Ce) scintillators and germanium detectors integrated into the DESPEC experimental setup commissioned for the Facility for Antiproton and Ion Research ( FAIR ) Phase -0, Darmstadt, Germany. The excited states in 95 Rh were populated primarily via the /3 decays of 95 Pd nuclei, produced in the projectile fragmentation of a 850 MeV / nucleon 124 Xe beam impinging on a 4 g / cm 2 9 Be target. The deduced electromagnetic E2 transition strengths for the gamma -ray cascade within the multiplet structure depopulating from the isomeric I pi = 21 / 2 + state are found to exhibit strong deviations from predictions of standard shell model calculations which feature approximately conserved seniority symmetry. In particular, the observation of a strongly suppressed E2 strength for the 13 / 2 + -> 9 / 2 + ground state transition cannot be explained by calculations employing standard interactions. This remarkable result may require revision of the nucleon-nucleon interactions employed in state-of-the-art theoretical model calculations, and might also point to the need for including three-body forces in the Hamiltonian.

Abstract: An amplitude analysis of the B-0 -> K*(0) mu(+)mu(-) decay is presented using a dataset corresponding to an integrated luminosity of 4.7 fb(-1) of pp collision data collected with the LHCb experiment. For the first time, the coefficients associated to short-distance physics effects, sensitive to processes beyond the standard model, are extracted directly from the data through a q(2)-unbinned amplitude analysis, where q(2) is the mu(+)mu(-) invariant mass squared. Long-distance contributions, which originate from nonfactorizable QCD processes, are systematically investigated, and the most accurate assessment to date of their impact on the physical observables is obtained. The pattern of measured corrections to the short-distance couplings is found to be consistent with previous analyses of b- to s-quark transitions, with the largest discrepancy from the standard model predictions found to be at the level of 1.8 standard deviations. The global significance of the observed differences in the decay is 1.4 standard deviations.