Abstract: Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range.

Abstract: We present a detailed study of the lowest-lying 1/2(-) and 3/2(-) Lambda Q resonances both in the heavy 2 2 quark (bottom and charm) and the strange sectors. We have paid special attention to the interplay between the constituent quark-model and chiral baryon-meson degrees of freedom, which are coupled using a unitarized scheme consistent with leading-order heavy quark symmetries. We show that the Lambda(b)(5912) [J(P) = 1/2(-)], Lambda(b)(5920) [J(P) = 3/2(-)] and the Lambda(c)(2625) [J(P) = 3/2-], and the Lambda(1520) [J(P) = 3/2(-)] admitting larger breaking corrections, are heavyquark spin-flavor siblings. They can be seen as dressed quark-model states with Sigma Q(()*()) pi molecular components of the order of 30%. The J(P)=1(-) Lambda(2595) has, however, a higher molecular 2 probability of at least 50%, and even values greater than 70% can be easily accommodated. This is because it is located almost on top of the threshold of the Sigma(c)pi pair, which largely influences its properties. Although the light degrees of freedom in this resonance would be coupled to spin-parity 1(-) as in the Lambda(b)(5912), Lambda(b)(5920) and Lambda(c)(2625), the Lambda(c)(2595) should not be considered as a heavy-quark spin-flavor partner of the former ones. We also show that the Lambda(1405) chiral two-pole pattern does not have analogs in the 1 – charmed and bottomed sectors, because the 2 N D-(*()) and N (B) over bar (()*()) channels do not play for heavy quarks the decisive role that the N (K) over bar does in the strange sector, and the notable influence of the bare quark-model states for the charm and bottom resonances. Finally, we predict the existence of two Lambda(b)(6070) and two Lambda(c)(2765) heavy-quark spin and flavor sibling odd parity states.

Abstract: A measurement of the charge asymmetry in top-quark pair (tt¯) production in association with a photon is presented. The measurement is performed in the single-lepton tt¯ decay channel using proton-proton collision data collected with the ATLAS detector at the Large Hadron Collider at CERN at a centre-of-mass-energy of 13 TeV during the years 2015-2018, corresponding to an integrated luminosity of 139 fb−1. The charge asymmetry is obtained from the distribution of the difference of the absolute rapidities of the top quark and antiquark using a profile likelihood unfolding approach. It is measured to be AC=−0.003±0.029 in agreement with the Standard Model expectation.

Abstract: This Letter presents the measurement of the fiducial and differential cross-sections of the electroweak production of a Zγ pair in association with two jets. The analysis uses 140 fb−1 of LHC proton-proton collision data taken at s√=13 TeV recorded by the ATLAS detector during the years 2015-2018. Events with a Z boson candidate decaying into either an e+e− or μ+μ− pair, a photon and two jets are selected. The electroweak component is extracted by requiring a large dijet invariant mass and a large rapidity gap between the two jets and is measured with an observed and expected significance well above five standard deviations. The fiducial pp→Zγjj cross-section for the electroweak production is measured to be 3.6 ± 0.5 fb. The total fiducial cross-section that also includes contributions where the jets arise from strong interactions is measured to be 16.8+2.0−1.8 fb. The results are consistent with the Standard Model predictions. Differential cross-sections are also measured using the same events and are compared with parton-shower Monte Carlo simulations. Good agreement is observed between data and predictions.

Abstract: The CP properties of the coupling between the Higgs boson and the top quark are investigated using 139 fb(-1) of proton-proton collision data recorded by the ATLAS experiment at the LHC at a centre-of-mass energy of root s = 13 TeV. The CP structure of the top quark-Higgs boson Yukawa coupling is probed in events with a Higgs boson decaying into a pair of b-quarks and produced in association with either a pair of top quarks, t (t) over barH or a single top quark, tH. Events containing one or two electrons or muons are used for the measurement. Multivariate techniques are used to select regions enriched in t (t) over barh and tH events, where dedicated SP-sensitive observables are exploited. In an extension of the Standard Model (SM) with a CP-odd admixture in the top-Higgs Yukawa coupling, the mixing angle between CP-even and CP-odd couplings is measured to be alpha = 11 degrees(+52 degrees)(-73 degrees) compatible with the SM prediction corresponding to alpha = 0.