| Records |
| Author |
Lerendegui-Marco, J.; Balibrea-Correa, J.; Babiano-Suarez, V.; Ladarescu, I.; Domingo-Pardo, C. |
| Title |
Towards machine learning aided real-time range imaging in proton therapy |
Type |
Journal Article |
| Year |
2022 |
Publication  |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
| Volume |
12 |
Issue |
1 |
Pages |
2735 - 17pp |
| Keywords |
|
| Abstract |
Compton imaging represents a promising technique for range verification in proton therapy treatments. In this work, we report on the advantageous aspects of the i-TED detector for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that have been specifically designed for neutron-capture nuclear physics experiments, which are characterized by gamma-ray energies spanning up to 5-6 MeV, rather low gamma-ray emission yields and very intense neutron induced gamma-ray backgrounds. Our developments to cope with these three aspects are concomitant with those required in the field of hadron therapy, especially in terms of high efficiency for real-time monitoring, low sensitivity to neutron backgrounds and reliable performance at the high gamma-ray energies. We find that signal-to-background ratios can be appreciably improved with i-TED thanks to its light-weight design and the low neutron-capture cross sections of its LaCl3 crystals, when compared to other similar systems based on LYSO, CdZnTe or LaBr3. Its high time-resolution (CRT similar to 500 ps) represents an additional advantage for background suppression when operated in pulsed HT mode. Each i-TED Compton module features two detection planes of very large LaCl3 monolithic crystals, thereby achieving a high efficiency in coincidence of 0.2% for a point-like 1 MeV gamma-ray source at 5 cm distance. This leads to sufficient statistics for reliable image reconstruction with an array of four i-TED detectors assuming clinical intensities of 10(8) protons per treatment point. The use of a two-plane design instead of three-planes has been preferred owing to the higher attainable efficiency for double time-coincidences than for threefold events. The loss of full-energy events for high energy gamma-rays is compensated by means of machine-learning based algorithms, which allow one to enhance the signal-to-total ratio up to a factor of 2. |
| Address |
[Lerendegui-Marco, Jorge; Balibrea-Correa, Javier; Babiano-Suarez, Victor; Ladarescu, Ion; Domingo-Pardo, Cesar] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: jorge.lerendegui@ific.uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Nature Portfolio |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
|
| ISSN |
2045-2322 |
ISBN |
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Medium |
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| Area |
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Expedition |
|
Conference |
|
| Notes |
WOS:000757537100018 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
5136 |
| Permanent link to this record |
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| Author |
Tortajada, S.; Albiol, F.; Caballero, L.; Albiol, A.; Leganes-Nieto, J.L. |
| Title |
A portable geometry-independent tomographic system for gamma-ray, a next generation of nuclear waste characterization |
Type |
Journal Article |
| Year |
2023 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
| Volume |
13 |
Issue |
1 |
Pages |
12284 - 10pp |
| Keywords |
|
| Abstract |
One of the main activities of the nuclear industry is the characterisation of radioactive waste based on the detection of gamma radiation. Large volumes of radioactive waste are classified according to their average activity, but often the radioactivity exceeds the maximum allowed by regulators in specific parts of the bulk. In addition, the detection of the radiation is currently based on static detection systems where the geometry of the bulk is fixed and well known. Furthermore, these systems are not portable and depend on the transport of waste to the places where the detection systems are located. However, there are situations where the geometry varies and where moving waste is complex. This is especially true in compromised situations.We present a new model for nuclear waste management based on a portable and geometry-independent tomographic system for three-dimensional image reconstruction for gamma radiation detection. The system relies on a combination of a gamma radiation camera and a visible camera that allows to visualise radioactivity using augmented reality and artificial computer vision techniques. This novel tomographic system has the potential to be a disruptive innovation in the nuclear industry for nuclear waste management. |
| Address |
[Tortajada, Salvador; Albiol, Francisco; Caballero, Luis] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46980 Paterna Valencia, Spain, Email: s.tortajada@ific.uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Nature Portfolio |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
2045-2322 |
ISBN |
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Medium |
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| Area |
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Expedition |
|
Conference |
|
| Notes |
WOS:001041587900052 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
5612 |
| Permanent link to this record |
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| Author |
Penas, J.; Alejo, A.; Bembibre, A.; Apiñaniz, J.I.; Garcia-Garcia, E.; Guerrero, C.; Henares, J.L.; Hernandez-Palmero, I.; Mendez, C.; Millan-Callado, M.A.; Puyuelo-Valdes, P.; Seimetz, M.; Benlliure, J. |
| Title |
Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source |
Type |
Journal Article |
| Year |
2024 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
| Volume |
14 |
Issue |
1 |
Pages |
11448 - 12pp |
| Keywords |
|
| Abstract |
Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range. |
| Address |
[Penas, Juan; Alejo, Aaron; Bembibre, Adrian; Benlliure, Jose] Univ Santiago de Compostela, Inst Galego Fis Altas Enerxias IGFAE, Santiago De Compostela 15782, Spain, Email: j.benlliure@usc.es |
| Corporate Author |
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Thesis |
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| Publisher |
Nature Portfolio |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
2045-2322 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:001228252900017 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
6143 |
| Permanent link to this record |
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| Author |
LHCb Collaboration (Aaij, R. et al); Garcia Martin, L.M.; Henry, L.; Jashal, B.K.; Martinez-Vidal, F.; Oyanguren, A.; Remon Alepuz, C.; Ruiz Vidal, J.; Sanchez Mayordomo, C. |
| Title |
Search for the doubly charmed baryon Xi(+)(cc) |
Type |
Journal Article |
| Year |
2020 |
Publication |
Science China-Physics Mechanics & Astronomy |
Abbreviated Journal |
Sci. China-Phys. Mech. Astron. |
| Volume |
63 |
Issue |
2 |
Pages |
221062 - 15pp |
| Keywords |
charmed baryons; limits on production of particles; charmed quarks; experimental tests |
| Abstract |
A search for the doubly charmed baryon.+ cc is performed through its decay to the.+ c K- p+ final state, using proton-proton collision data collected with the LHCb detector at centre-of-mass energies of 7, 8 and 13 TeV. The data correspond to a total integrated luminosity of 9 fb-1. No significant signal is observed in the mass range from 3.4 to 3.8 GeV/c2. Upper limits are set at 95% credibility level on the ratio of the.+ cc production cross-section times the branching fraction to that of.+ c and.++ cc baryons. The limits are determined as functions of the.+ cc mass for di fferent lifetime hypotheses, in the rapidity range from 2.0 to 4.5 and the transverse momentum range from 4 to 15 GeV/c. |
| Address |
[Bediaga, I.; Cruz Torres, M.; De Miranda, J. M.; Gomes, A.; Massafferri, A.; dos Reis, A. C.; Soares Lavra, L.; Tourinho Jadallah Aoude, R.] CBPF, Rio De Janeiro, Brazil, Email: maria.vieites.diaz@cern.ch |
| Corporate Author |
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Thesis |
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| Publisher |
Science Press |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1674-7348 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000526889100001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
4376 |
| Permanent link to this record |
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| Author |
LHCb Collaboration (Aaij, R. et al); Jashal, B.K.; Martinez-Vidal, F.; Oyanguren, A.; Remon Alepuz, C.; Ruiz Vidal, J. |
| Title |
Search for the doubly charmed baryon Omega(+)(cc) |
Type |
Journal Article |
| Year |
2021 |
Publication |
Science China-Physics Mechanics & Astronomy |
Abbreviated Journal |
Sci. China-Phys. Mech. Astron. |
| Volume |
64 |
Issue |
10 |
Pages |
101062 - 12pp |
| Keywords |
charmed baryons; limits on production of particles; charmed quarks; experimental tests |
| Abstract |
A search for the doubly charmed baryon Omega(+)(cc) with the decay mode Omega(+)(cc) -> Xi K-+(c)-pi(+) is performed using proton-proton collision data at a centre-of-mass energy of 13 TeV collected by the LHCb experiment from 2016 to 2018, corresponding to an integrated luminosity of 5.4 fb(-1). No significant signal is observed within the invariant mass range of 3.6 to 4.0GeV/c(2). Upper limits are set on the ratio R of the production cross-section times the total branching fraction of the Omega(+)(cc) -> Xi K-+(c)-pi(+) decay with respect to the Xi(++)(cc) -> Lambda K-+(c)-pi(+)pi(+) decay. Upper limits at 95% credibility level for R in the range 0.005 to 0.11 are obtained for different hypotheses on the Omega(+)(cc) mass and lifetime in the rapidity range from 2.0 to 4.5 and transverse momentum range from 4 to 15 GeV/c. |
| Address |
[Baptista Leite, J.; Bediaga, I; Cruz Torres, M.; De Miranda, J. M.; dos Reis, A. C.; Gomes, A.; Massafferri, A.; Machado, D. Torres] Ctr Brasileiro Pesquisas Fis CBPF, Rio De Janeiro, Brazil |
| Corporate Author |
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Thesis |
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| Publisher |
Science Press |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
|
Edition |
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| ISSN |
1674-7348 |
ISBN |
|
Medium |
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| Area |
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Expedition |
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Conference |
|
| Notes |
WOS:000694853300003 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
4971 |
| Permanent link to this record |
