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Author |
Hueso-Gonzalez, F.; Vijande, J.; Ballester, F.; Perez-Calatayud, J.; Siebert, F.A. |
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Title |
A simple analytical method for heterogeneity corrections in low dose rate prostate brachytherapy |
Type |
Journal Article |
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Year |
2015 |
Publication  |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
60 |
Issue |
14 |
Pages |
5455-5469 |
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Keywords |
brachytherapy; low dose rate; heterogeneities; prostate; calcifications |
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Abstract |
In low energy brachytherapy, the presence of tissue heterogeneities contributes significantly to the discrepancies observed between treatment plan and delivered dose. In this work, we present a simplified analytical dose calculation algorithm for heterogeneous tissue. We compare it with Monte Carlo computations and assess its suitability for integration in clinical treatment planning systems. The algorithm, named as RayStretch, is based on the classic equivalent path length method and TG-43 reference data. Analytical and Monte Carlo dose calculations using Penelope2008 are compared for a benchmark case: a prostate patient with calcifications. The results show a remarkable agreement between simulation and algorithm, the latter having, in addition, a high calculation speed. The proposed analytical model is compatible with clinical real-time treatment planning systems based on TG-43 consensus datasets for improving dose calculation and treatment quality in heterogeneous tissue. Moreover, the algorithm is applicable for any type of heterogeneities. |
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Address |
[Hueso-Gonzalez, Fernando; Vijande, Javier; Ballester, Facundo] Univ Valencia, Dept Atom Mol & Nucl Phys, E-46100 Burjassot, Spain, Email: Javier.Vijande@uv.es |
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Publisher |
Iop Publishing Ltd |
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English |
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ISSN |
0031-9155 |
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Conference |
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Notes |
WOS:000357620400009 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2296 |
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Author |
Solevi, P.; Magrin, G.; Moro, D.; Mayer, R. |
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Title |
Monte Carlo study of microdosimetric diamond detectors |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
60 |
Issue |
18 |
Pages |
7069-7083 |
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Keywords |
ion-beam therapy; microdosimetry; diamonds; GATE |
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Abstract |
Ion-beam therapy provides a high dose conformity and increased radiobiological effectiveness with respect to conventional radiation-therapy. Strict constraints on the maximum uncertainty on the biological weighted dose and consequently on the biological weighting factor require the determination of the radiation quality, defined as the types and energy spectra of the radiation at a specific point. However the experimental determination of radiation quality, in particular for an internal target, is not simple and the features of ion interactions and treatment delivery require dedicated and optimized detectors. Recently chemical vapor deposition (CVD) diamond detectors have been suggested as ion-beam therapy microdosimeters. Diamond detectors can be manufactured with small cross sections and thin shapes, ideal to cope with the high fluence rate. However the sensitive volume of solid state detectors significantly deviates from conventional microdosimeters, with a diameter that can be up to 1000 times the height. This difference requires a redefinition of the concept of sensitive thickness and a deep study of the secondary to primary radiation, of the wall effects and of the impact of the orientation of the detector with respect to the radiation field. The present work intends to study through Monte Carlo simulations the impact of the detector geometry on the determination of radiation quality quantities, in particular on the relative contribution of primary and secondary radiation. The dependence of microdosimetric quantities such as the unrestricted linear energy L and the lineal energy y are investigated for different detector cross sections, by varying the particle type (carbon ions and protons) and its energy. |
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Address |
[Solevi, Paola; Magrin, Giulio; Mayer, Ramona] EBG MedAustron, A-2700 Wiener Neustadt, Austria, Email: paola.solevi@ovgu.de |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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ISSN |
0031-9155 |
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Conference |
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Notes |
WOS:000361124000004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2379 |
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Author |
Olmo, G.J.; Rubiera-Garcia, D. |
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Title |
Brane-world and loop cosmology from a gravity-matter coupling perspective |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
740 |
Issue |
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Pages |
73-79 |
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Keywords |
Modified gravity; Palatini formalism; f(R) theories; Gravity-matter coupling; Quadratic cosmology |
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Abstract |
We show that the effective brane-world and the loop quantum cosmology background expansion histories can be reproduced from a modified gravity perspective in terms of an f (R) gravity action plus a g(R) term non-minimally coupled with the matter Lagrangian. The reconstruction algorithm that we provide depends on a free function of the matter density that must be specified in each case and allows to obtain analytical solutions always. In the simplest cases, the function f (R) is quadratic in the Ricci scalar, R, whereas g(R) is linear. Our approach is compared with recent results in the literature. We show that working in the Palatini formalism there is no need to impose any constraint that keeps the equations second order, which is a key requirement for the successful implementation of the reconstruction algorithm. |
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Address |
[Olmo, Gonzalo J.] Univ Valencia, CSIC, Ctr Mixto, Dept Fis Teor, E-46100 Valencia, Spain, Email: gonzalo.olmo@csic.es; |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0370-2693 |
ISBN |
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Conference |
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Notes |
WOS:000347046200013 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2099 |
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Author |
Wang, E.; Alvarez-Ruso, L.; Nieves, J. |
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Title |
Single photon events from neutral current interactions at MiniBooNE |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
740 |
Issue |
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Pages |
16-22 |
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Keywords |
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Abstract |
The MiniBooNE experiment has reported results from the analysis of v(e) and (v) over bar (e) appearance searches, which show an excess of signal-like events at low reconstructed neutrino energies, with respect to the expected background. A significant component of this background comes from photon emission induced by (anti) neutrino neutral current interactions with nucleons and nuclei. With an improved microscopic model for these reactions, we predict the number and distributions of photon events at the MiniBooNE detector. Our results are compared to the MiniBooNE in situ estimate and to other theoretical approaches. We find that, according to our model, neutral current photon emission from single-nucleon currents is insufficient to explain the events excess observed by MiniBooNE in both neutrino and antineutrino modes. |
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Address |
[Wang, En; Alvarez-Ruso, Luis; Nieves, Juan] Univ Valencia, Ctr Mixto CSIC, Inst Fis Corpuscular IFIC, Inst Invest Paterna, E-46071 Valencia, Spain, Email: luis.alvarez@ific.uv.es |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0370-2693 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000347046200003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2094 |
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| Permanent link to this record |
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Author |
ATLAS Collaboration (Aad, G. et al); Cabrera Urban, S.; Castillo Gimenez, V.; Costa, M.J.; Ferrer, A.; Fiorini, L.; Fuster, J.; Garcia, C.; Garcia Navarro, J.E.; Gonzalez de la Hoz, S.; Hernandez Jimenez, Y.; Higon-Rodriguez, E.; Irles Quiles, A.; Kaci, M.; King, M.; Lacasta, C.; Lacuesta, V.R.; Marti-Garcia, S.; Mitsou, V.A.; Moles-Valls, R.; Oliver Garcia, E.; Pedraza Lopez, S.; Perez Garcia-Estañ, M.T.; Romero Adam, E.; Ros, E.; Salt, J.; Sanchez Martinez, V.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valero, A.; Valladolid Gallego, E.; Valls Ferrer, J.A.; Vos, M. |
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Title |
Search for s-channel single top-quark production in proton-proton collisions at root s=8 TeV with the ATLAS detector |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
740 |
Issue |
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Pages |
118-136 |
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Keywords |
ATLAS; Top quark; Electroweak production; s-Channel |
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Abstract |
This Letter presents a search at the LHC for s-channel single top-quark production in proton-proton collisions at a centre-of-mass energy of 8 TeV. The analyzed data set was recorded by the ATLAS detector and corresponds to an integrated luminosity of 20.3 fb(-1). Selected events contain one charged lepton, large missing transverse momentum and exactly two b-tagged jets. A multivariate event classifier based on boosted decision trees is developed to discriminate s-channel single top-quark events from the main background contributions. The signal extraction is based on a binned maximum-likelihood fit of the output classifier distribution. The analysis leads to an upper limit on the s-channel single topquark production cross-section of 14.6 pb at the 95% confidence level. The fit gives a cross-section of sigma(s) = 5.0 +/- 4.3 pb, consistent with the Standard Model expectation. |
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Address |
[Jackson, P.; Lee, L.; Leone, S.; Soni, N.; White, M. J.] Univ Adelaide, Dept Phys, Adelaide, SA, Australia |
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Corporate Author |
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Thesis |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0370-2693 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000347046200017 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2095 |
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