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Author Ma, Y.Z.; Vijande, J.; Ballester, F.; Tedgren, A.C.; Granero, D.; Haworth, A.; Mourtada, F.; Fonseca, G.P.; Zourari, K.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.; Chamberland, M.J.P.; Thomson, R.M.; Verhaegen, F.; Beaulieu, L.
Title A generic TG-186 shielded applicator for commissioning model-based dose calculation algorithms for high-dose-rate Ir-192 brachytherapy Type Journal Article
Year 2017 Publication (up) Medical Physics Abbreviated Journal Med. Phys.
Volume 44 Issue 11 Pages 5961-5976
Keywords Ir-192; HDR brachytherapy; model based dose calculation; Monte Carlo methods; shielded applicator; TG-186
Abstract PurposeA joint working group was created by the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) with the charge, among others, to develop a set of well-defined test case plans and perform calculations and comparisons with model-based dose calculation algorithms (MBDCAs). Its main goal is to facilitate a smooth transition from the AAPM Task Group No. 43 (TG-43) dose calculation formalism, widely being used in clinical practice for brachytherapy, to the one proposed by Task Group No. 186 (TG-186) for MBDCAs. To do so, in this work a hypothetical, generic high-dose rate (HDR) Ir-192 shielded applicator has been designed and benchmarked. MethodsA generic HDR Ir-192 shielded applicator was designed based on three commercially available gynecological applicators as well as a virtual cubic water phantom that can be imported into any DICOM-RT compatible treatment planning system (TPS). The absorbed dose distribution around the applicator with the TG-186 Ir-192 source located at one dwell position at its center was computed using two commercial TPSs incorporating MBDCAs (Oncentra((R)) Brachy with Advanced Collapsed-cone Engine, ACE, and BrachyVision ACUROS) and state-of-the-art Monte Carlo (MC) codes, including ALGEBRA, BrachyDose, egs_brachy, Geant4, MCNP6, and Penelope2008. TPS-based volumetric dose distributions for the previously reported source centered in water and source displaced test cases, and the new source centered in applicator test case, were analyzed here using the MCNP6 dose distribution as a reference. Volumetric dose comparisons of TPS results against results for the other MC codes were also performed. Distributions of local and global dose difference ratios are reported. ResultsThe local dose differences among MC codes are comparable to the statistical uncertainties of the reference datasets for the source centered in water and source displaced test cases and for the clinically relevant part of the unshielded volume in the source centered in applicator case. Larger local differences appear in the shielded volume or at large distances. Considering clinically relevant regions, global dose differences are smaller than the local ones. The most disadvantageous case for the MBDCAs is the one including the shielded applicator. In this case, ACUROS agrees with MC within [-4.2%, +4.2%] for the majority of voxels (95%) while presenting dose differences within [-0.12%, +0.12%] of the dose at a clinically relevant reference point. For ACE, 95% of the total volume presents differences with respect to MC in the range [-1.7%, +0.4%] of the dose at the reference point. ConclusionsThe combination of the generic source and generic shielded applicator, together with the previously developed test cases and reference datasets (available in the Brachytherapy Source Registry), lay a solid foundation in supporting uniform commissioning procedures and direct comparisons among treatment planning systems for HDR Ir-192 brachytherapy.
Address [Ma, Yunzhi; Beaulieu, Luc] CHU Quebec, Dept Radio Oncol & Axe Oncol, Ctr Rech, Quebec City, PQ G1R 2J6, Canada, Email: yunzhi.Ma@crchuq.ulaval.ca
Corporate Author Thesis
Publisher Wiley Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0094-2405 ISBN Medium
Area Expedition Conference
Notes WOS:000414970800039 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3370
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Author ANTARES Collaboration (Albert, A. et al); Barrios-Marti, J.; Hernandez-Rey, J.J.; Illuminati, G.; Lotze, M.; Tönnis, C.; Zornoza, J.D.; Zuñiga, J.
Title Search for high-energy neutrinos from bright GRBs with ANTARES Type Journal Article
Year 2017 Publication (up) Monthly Notices of the Royal Astronomical Society Abbreviated Journal Mon. Not. Roy. Astron. Soc.
Volume 469 Issue 1 Pages 906-915
Keywords acceleration of particles; neutrinos; gamma-ray burst: individual: GRB 080916C; gamma-ray burst: individual: GRB 110918A; gamma-ray burst: individual: GRB 130427A; gamma-ray burst: individual: GRB 130505A
Abstract Gamma-ray bursts are thought to be sites of hadronic acceleration, thus neutrinos are expected from the decay of charged particles, produced in p gamma interactions. The methods and results of a search for muon neutrinos in the data of the ANTARES neutrino telescope from four bright GRBs (GRB 080916C, GRB 110918A, GRB 130427A and GRB 130505A) observed between 2008 and 2013 are presented. Two scenarios of the fireball model have been investigated: the internal shock scenario, leading to the production of neutrinos with energies mainly above 100 TeV, and the photospheric scenario, characterized by a low-energy component in neutrino spectra due to the assumption of neutrino production closer to the central engine. Since no neutrino events have been detected in temporal and spatial coincidence with these bursts, upper limits at 90 per cent confidence level on the expected neutrino fluxes are derived. The non-detection allows for directly constraining the bulk Lorentz factor of the jet Gamma and the baryon loading f(p).
Address [Albert, A.; Drouhin, D.; Racca, C.] Univ Haute Alsace, GRPHE, Inst Univ Technol Colmar, 34 Rue Grillenbreit BP 50568, F-68008 Colmar, France, Email: silvia.celli@gssi.infn.it
Corporate Author Thesis
Publisher Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0035-8711 ISBN Medium
Area Expedition Conference
Notes WOS:000402825000062 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3159
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Author Moline, A.; Sanchez-Conde, M.A.; Palomares-Ruiz, S.; Prada, F.
Title Characterization of subhalo structural properties and implications for dark matter annihilation signals Type Journal Article
Year 2017 Publication (up) Monthly Notices of the Royal Astronomical Society Abbreviated Journal Mon. Not. Roy. Astron. Soc.
Volume 466 Issue 4 Pages 4974-4990
Keywords galaxies: haloes; cosmology: theory; dark matter
Abstract A prediction of the standard Lambda cold dark matter cosmology is that dark matter (DM) haloes are teeming with numerous self-bound substructure or subhaloes. The precise properties of these subhaloes represent important probes of the underlying cosmological model. We use data from Via Lactea II and Exploring the Local Volume in Simulations N-body simulations to learn about the structure of subhaloes with masses 10(6)-10(11) h(-1) M circle dot. Thanks to a superb subhalo statistics, we study subhalo properties as a function of distance to host halo centre and subhalo mass, and provide a set of fits that accurately describe the subhalo structure. We also investigate the role of subhaloes on the search for DM annihilation. Previous work has shown that subhaloes are expected to boost the DM signal of their host haloes significantly. Yet, these works traditionally assumed that subhaloes exhibit similar structural properties than those of field haloes, while it is known that subhaloes are more concentrated. Building upon our N-body data analysis, we refine the substructure boost model of Sanchez-Conde & Prada (2014), and find boosts that are a factor 2-3 higher. We further refine the model to include unavoidable tidal stripping effects on the subhalo population. For field haloes, this introduces a moderate (similar to 20-30 per cent) suppression. Yet, for subhaloes like those hosting dwarf galaxy satellites, tidal stripping plays a critical role, the boost being at the level of a few tens of percent at most. We provide a parametrization of the boost for field haloes that can be safely applied over a wide halo mass range.
Address [Moline, Angeles] Univ Tecn Lisboa, CFTP, Inst Super Tecn, Av Rovisco Pais 1, P-1049001 Lisbon, Portugal, Email: angeles.moline@gmail.com;
Corporate Author Thesis
Publisher Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0035-8711 ISBN Medium
Area Expedition Conference
Notes WOS:000402849400088 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3164
Permanent link to this record
 

 
Author ANTARES and HESS Collaborations (Petroff, E. et al); Barrios-Marti, J.; Hernandez-Rey, J.J.; Illuminati, G.; Lotze, M.; Tönnis, C.; Zornoza, J.D.; Zuñiga, J.
Title A polarized fast radio burst at low Galactic latitude Type Journal Article
Year 2017 Publication (up) Monthly Notices of the Royal Astronomical Society Abbreviated Journal Mon. Not. Roy. Astron. Soc.
Volume 469 Issue 4 Pages 4465-4482
Keywords polarization; methods: data analysis; surveys; ISM: structure
Abstract We report on the discovery of a new fast radio burst (FRB), FRB 150215, with the Parkes radio telescope on 2015 February 15. The burst was detected in real time with a dispersion measure (DM) of 1105.6 +/- 0.8 pc cm(-3), a pulse duration of 2.8(-0.5)(+1.2) ms, and a measured peak flux density assuming that the burst was at beam centre of 0.7(-0.1)(+0.2) Jy. The FRB originated at a Galactic longitude and latitude of 24.66 degrees, 5.28 degrees and 25 degrees away from the Galactic Center. The burst was found to be 43 +/- 5 per cent linearly polarized with a rotation measure (RM) in the range -9 < RM < 12 rad m(-2) (95 per cent confidence level), consistent with zero. The burst was followed up with 11 telescopes to search for radio, optical, X-ray, gamma-ray and neutrino emission. Neither transient nor variable emission was found to be associated with the burst and no repeat pulses have been observed in 17.25 h of observing. The sightline to the burst is close to the Galactic plane and the observed physical properties of FRB 150215 demonstrate the existence of sight lines of anomalously low RM for a given electron column density. The Galactic RM foreground may approach a null value due to magnetic field reversals along the line of sight, a decreased total electron column density from the Milky Way, or some combination of these effects. A lower Galactic DM contribution might explain why this burst was detectable whereas previous searches at low latitude have had lower detection rates than those out of the plane.
Address [Petroff, E.; Rowlinson, A.] Netherlands Inst Radio Astron, ASTRON, Postbus 2, NL-7990 AA Dwingeloo, Netherlands
Corporate Author Thesis
Publisher Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0035-8711 ISBN Medium
Area Expedition Conference
Notes WOS:000406837900051 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3241
Permanent link to this record
 

 
Author LHCb Collaboration (Aaij, R. et al); Garcia Martin, L.M.; Martinez-Vidal, F.; Oyanguren, A.; Remon Alepuz, C.; Ruiz Valls, P.; Sanchez Mayordomo, C.
Title Measurement of matter-antimatter differences in beauty baryon decays Type Journal Article
Year 2017 Publication (up) Nature Physics Abbreviated Journal Nat. Phys.
Volume 13 Issue 4 Pages 391-396
Keywords
Abstract Differences in the behaviour of matter and antimatter have been observed in K and B meson decays, but not yet in any baryon decay. Such differences are associated with the non-invariance of fundamental interactions under the combined chargeconjugation and parity transformations, known as CP violation. Here, using data from the LHCb experiment at the Large Hadron Collider, we search for CP-violating asymmetries in the decay angle distributions of A(b)(0) baryons decaying to p pi(-)pi(+)pi(-) and p pi-K+K- final states. These four-body hadronic decays are a promising place to search for sources of CP violation both within and beyond the standard model of particle physics. We find evidence for CP violation in A(b)(0) to p pi(-)pi(+)pi(-) decays with a statistical significance corresponding to 3.3 standard deviations including systematic uncertainties. This represents the first evidence for CP violation in the baryon sector.
Address
Corporate Author Thesis
Publisher Nature Publishing Group Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1745-2473 ISBN Medium
Area Expedition Conference
Notes WOS:000398262900020 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3170
Permanent link to this record